Unmatched Supps Longevity Multi: Kris Gethin's Revolutionary 7-Formula Health System

When most supplement companies talk about "complete health support", they usually mean cramming everything into a few overcrowded capsules. Unmatched Supps Longevity Multi takes a radically different approach: seven distinct, targeted formulas that work synergistically to address the fundamental pillars of long-term health and vitality.

Unmatched Supps Longevity Multi+ is a 7-packet daily system that makes your average multivitamin look like child's play. We're talking clinical doses of everything from Spectra antioxidants to spermidine for cellular longevity.

You've seen vita-packs... now it's time to meet a longevity-inspired one from Unmatched!

This clearly isn't just another multivitamin. It's a comprehensive daily health system that reflects founders Kris Gethin and Doug Miller's philosophy of optimizing both immediate performance and long-term health span. Just as their 2SHRED AM/PM System revolutionized weight management with targeted morning and evening formulas, and Longevity Test addressed hormonal optimization from multiple angles, the Longevity Multi tackles the complexity of total-body wellness with surgical precision.

Each component serves a specific purpose: foundational nutrition, cognitive enhancement, joint support, liver optimization, gut health, cardiovascular wellness, and cellular longevity. Rather than compromising on dosages or effectiveness, this system ensures that each area receives the clinical attention it deserves.

True to the Unmatched commitment to transparency and quality, every ingredient is included at meaningful dosages, sourced from premium suppliers, and formulated without artificial sweeteners or unnecessary fillers. This is supplementation for those who refuse to settle for mediocrity in their health optimization journey.

Before we dive into the comprehensive breakdown, sign up for PricePlow's Unmatched Supps news alerts and check current pricing below:

Longevity Multi: Seven Pillars of Complete Health

The Longevity Multi system addresses the fundamental areas that determine both immediate vitality and long-term health span through seven targeted formulas:

Multi-Vitamin & Mineral Foundation

The cornerstone of the system provides essential vitamins and minerals in their most bioavailable forms, enhanced with a premium antioxidant blend:

Key Highlights:

• Vitamin D3 at 2500 IU (500% DV) for immune and bone health
• Methylated B-vitamins including B12 as methylcobalamin and folate as Quatrefolic for optimal absorption
• Chelated minerals like zinc citrate and magnesium malate for enhanced bioavailability
• Spectra ORAC Blend (100mg) - a comprehensive antioxidant complex from whole food sources

• Vitamin D3 at 2500 IU (500% DV)

  Vitamin D3 stands as one of the most crucial yet commonly deficient nutrients in modern society, making its generous inclusion here a cornerstone of the foundation formula. At 2500 IU, this dose provides substantial support without approaching excessive levels, sitting comfortably within the safe upper limit of 4000 IU daily established by regulatory agencies.^[1]

  The benefits extend far beyond the traditional bone health focus. While vitamin D3 does regulate calcium absorption in the intestines and supports bone mineralization through its conversion to the active hormone calcitriol, emerging research has revealed its critical role in immune system modulation.^[2] Vitamin D receptors are found throughout immune cells, where adequate levels help shift immune function toward a more balanced, tolerogenic state that supports healthy inflammatory responses.

  The 2500 IU dosing hits the sweet spot for most adults -- sufficient to correct deficiency and maintain optimal 25-hydroxyvitamin D blood levels between 30-50 ng/mL without requiring individual monitoring.^[3] This is a practical, evidence-based approach to one of the most fundamental nutritional gaps in the modern diet.



• Quatrefolic (5-MTHF) - The Superior Folate Form - 400mcg DFE (100% DV)

  Rather than using synthetic folic acid, the Longevity Multi includes Quatrefolic, a premium form of 5-methyltetrahydrofolate (5-MTHF) - the naturally occurring, bioactive form of folate found in the body. This choice is a significant upgrade in bioavailability and effectiveness. Unlike folic acid, which requires conversion through the enzyme dihydrofolate reductase, 5-MTHF bypasses this rate-limiting step and is immediately available for cellular processes.^[4]

  The Quatrefolic form offers enhanced absorption even when gastrointestinal pH is altered and provides superior benefits for individuals with MTHFR gene polymorphisms, which affect up to 55% of the population and reduce the body's ability to convert synthetic folic acid into its active form.

• Zinc Citrate - 25mg (227% DV)

  Zinc citrate provides this essential mineral in a highly bioavailable chelated form that's superior to basic zinc oxide. As the second-most abundant trace mineral in the body, zinc plays critical roles in immune function, wound healing, and protein synthesis.^[5] The citrate chelation enhances absorption by protecting the zinc from interference by other minerals and dietary compounds that can block uptake.

  At 25mg, this dosage provides optimal support without approaching the 40mg upper limit (we don't suggest going any higher without normal blood tests), making it ideal for daily maintenance of zinc status. Zinc deficiency is surprisingly common, especially in those following plant-based diets or high-intensity training regimens, where this mineral becomes depleted more rapidly. Beyond immune support, zinc is essential for maintaining healthy testosterone levels, supporting cognitive function, and facilitating the thousands of enzymatic reactions that keep cellular metabolism running smoothly.

• Spectra ORAC Blend - 100mg

  

  Spectra provides antioxidant supplementation, delivering a comprehensive blend of over 29 fruit, vegetable, and herbal extracts standardized to provide broad-spectrum cellular protection. Unlike isolated antioxidants that target specific free radicals, this whole-food complex provides synergistic compounds including quercetin, chlorogenic acids from coffee fruit, catechins from green tea, and curcuminoids from turmeric that work together to support your body's natural defense systems.^[6]

  Clinical research demonstrates that Spectra significantly reduces both cellular and mitochondrial reactive oxygen species (ROS) generation while simultaneously increasing bioavailable nitric oxide levels and supporting healthy inflammatory responses. At 100mg, this dose provides the clinically studied amount that delivers measurable improvements in cellular vitality and oxidative stress markers within hours of consumption.

Nootropic Cognitive Support

Brain health becomes increasingly crucial as we age, and this formula addresses multiple aspects of cognitive function:

• Citicoline (Cognizin) - 125mg

  Citicoline stands as the premium choline source in this cognitive support formula, delivering both choline and cytidine in a single compound that crosses the blood-brain barrier efficiently. Unlike ordinary choline supplements, citicoline provides the building blocks for phosphatidylcholine synthesis - a critical phospholipid that makes up cellular membranes throughout the brain.^[7]

  The Cognizin name represents the clinically studied form of citicoline, manufactured by Kyowa Hakko under stringent quality standards. This compound functions as a precursor to acetylcholine, the neurotransmitter essential for learning and memory processes, while simultaneously supporting brain energy metabolism through enhanced mitochondrial function. Research demonstrates that citicoline helps maintain healthy neurotransmitter levels, supporting not only acetylcholine but also dopamine and norepinephrine pathways that influence focus and cognitive performance.

  

  At 125mg, this dosage provides the foundation for daily cognitive support, helping to maintain phospholipid metabolism in the brain and supporting healthy brain cell signaling. The dual-action mechanism makes citicoline uniquely effective - it delivers both the choline needed for neurotransmitter synthesis and the cytidine required for optimal membrane health, creating the conditions for sustained cognitive function throughout the day.

• Bacopa Monnieri Extract - 150mg (50% Bacosides)

  Bacopa monnieri has been treasured in Ayurvedic medicine for centuries as a brain tonic, and modern research validates its cognitive-enhancing properties. Standardized to 50% bacosides -- the primary bioactive compounds -- this extract supports memory formation, learning, and overall cognitive performance through multiple neurological pathways.

  The herb's mechanisms extend beyond simple neurotransmitter support. Bacopa enhances neuroplasticity by supporting brain-derived neurotrophic factor (BDNF) expression, promotes synaptic function, and provides neuroprotective effects through its antioxidant and anti-inflammatory actions.^[8] At 150mg, this dose provides the foundation for sustained cognitive enhancement, supporting both immediate mental clarity and long-term brain health as part of the comprehensive nootropic formula.

• Sabroxy (Oroxylum indicum Extract) - 100mg

  Sabroxy provides a standardized extract of Oroxylum indicum bark containing 10% oroxylin A, a bioactive flavonoid that supports cognitive function through multiple pathways. This Ayurvedic botanical has gained attention for its ability to enhance neuroplasticity and support brain-derived neurotrophic factor (BDNF) expression, a key protein involved in neuronal growth and memory formation.^[9]

  

  Clinical research demonstrates that Sabroxy supplementation can improve episodic memory, enhance working memory performance, and accelerate learning processes. The extract's primary compound, oroxylin A, appears to modulate GABA receptors and support healthy inflammatory responses in brain tissue, creating optimal conditions for cognitive enhancement and long-term neurological health.

• Huperzine A - 100mcg from 10mg toothed clubmoss extract

  Huperzine A serves as a natural acetylcholinesterase inhibitor derived from 10mg of Huperzia serrata (toothed clubmoss) extract standardized to 1% Huperzine A. This compound works by blocking the enzyme that breaks down acetylcholine, allowing the crucial neurotransmitter to remain active longer in synapses for enhanced learning and memory processes.^[10]

  Beyond its cholinergic effects, research demonstrates that Huperzine A provides multifaceted neuroprotection through antioxidant activity, mitochondrial support, and healthy inflammatory responses in brain tissue. The standardized extract ensures consistent potency while delivering this time-tested cognitive enhancer in a precise, effective dose.

Joint & Mobility Support

Movement quality directly impacts quality of life, making joint health a cornerstone of longevity:

• Turmeric Extract (95% Curcuminoids) - 350mg

  Turmeric extract standardized to 95% curcuminoids provides potent anti-inflammatory support that directly targets joint comfort and mobility. The primary bioactive compounds - curcumin, demethoxycurcumin, and bisdemethoxycurcumin - work synergistically to modulate inflammatory pathways, supporting healthy inflammatory responses throughout connective tissues.^[11]

  

  At 350mg of 95% standardized extract, this dosage delivers approximately 332mg of active curcuminoids -- a clinically meaningful amount that provides the foundation for daily joint health maintenance. The inclusion of BioPerine black pepper extract ensures optimal absorption of these powerful compounds, maximizing their bioavailability and therapeutic potential for long-term joint comfort and mobility support.

• BioPerine Black Pepper Extract - 10mg

  BioPerine is a standardized extract of Piper nigrum containing 95% piperine, the alkaloid responsible for black pepper's pungency and bioenhancement properties. While 10mg may seem modest, this precise dose delivers maximum absorption benefits without unnecessary excess. Piperine works by inhibiting glucuronidation enzymes in the liver and intestines, significantly enhancing the bioavailability of curcumin and other nutrients.^[12] Research demonstrates that piperine can increase curcumin absorption by up to 2000% in humans, transforming the turmeric extract from a poorly absorbed compound into a highly bioavailable therapeutic agent. This synergistic relationship ensures you receive the full anti-inflammatory benefits that make this joint support formula effective.

  Additionally, there's MSM (Methylsulfonylmethane) - 300mg supplies bioavailable sulfur compounds that support connective tissue health and recovery.

Liver Detoxification Support

The liver processes everything from environmental toxins to metabolic waste, making its optimization crucial for longevity:

• N-Acetyl Cysteine (NAC) - 600mg

  N-Acetyl Cysteine serves as the cornerstone of this liver support formula, functioning as a direct precursor to glutathione - your body's most powerful endogenous antioxidant and detoxification system. At 600mg, this dose provides clinically meaningful support for phase II liver detoxification pathways that process everything from environmental toxins to metabolic waste products.^[13]

  

  NAC works through dual mechanisms: it directly scavenges free radicals while simultaneously replenishing intracellular glutathione levels that become depleted through daily toxic exposure and metabolic stress. This combination makes NAC uniquely effective for supporting your liver's natural ability to neutralize harmful compounds and maintain optimal cellular health as part of your longevity optimization strategy.

• Milk Thistle Extract - 300mg

  Milk thistle extract provides 300mg of Silybum marianum seed extract, delivering silymarin compounds that have supported liver health for centuries. The active flavonolignans in silymarin work through multiple hepatoprotective mechanisms, including antioxidant activity, membrane stabilization, and support for healthy inflammatory responses in liver tissue.^[14]

  Modern research demonstrates that silymarin undergoes enterohepatic recirculation, concentrating specifically in liver cells where it supports phase II detoxification pathways and helps maintain healthy liver enzyme levels. At 300mg daily, this dosage provides meaningful support for liver regeneration and protection against oxidative stress, making it an ideal complement to NAC's glutathione-supporting effects in this comprehensive liver optimization formula.

• Ubiquinol - 30mg

  Ubiquinol provides the reduced, bioactive form of CoQ10 that delivers superior absorption compared to standard ubiquinone. This cellular powerhouse supports mitochondrial energy production while functioning as a potent antioxidant that protects against oxidative stress.^[15] The 30mg dose provides meaningful support for liver detoxification pathways, where optimal mitochondrial function becomes crucial for processing toxins and maintaining cellular health throughout the body's primary detoxification organ.

Gut Health & Digestion

Digestive health forms the foundation of nutrient absorption and immune function:

• Digestive Enzyme Blend (DigeSEB Super) - 100mg

  

  DigeSEB Super provides a comprehensive enzyme complex featuring amylase for carbohydrate breakdown, multiple proteases for protein digestion, lipase for fat metabolism, and specialized enzymes like cellulase and lactase for enhanced nutrient liberation. This blend addresses the reality that digestive capacity often declines with age and stress, leading to incomplete nutrient absorption despite quality food choices.^[16] The 100mg dose delivers meaningful support for optimizing digestion of proteins, fats, and carbohydrates, ensuring your body can fully utilize the nutrients from both food and the other components in this longevity system.

• Probiotic Blend - 10 Billion CFU

  The Probiotic Blend delivers 10 billion colony-forming units across 14 carefully selected strains spanning the Lactobacillus, Bifidobacterium, and Streptococcus genera. This multi-strain approach provides superior benefits compared to single-strain formulations through synergistic mechanisms that enhance pathogen inhibition, strengthen intestinal barrier function, and support immune modulation.^[17]

  The diverse strain profile includes key players like L. acidophilus for competitive exclusion of harmful bacteria, Bifidobacterium breve for supporting healthy inflammatory responses, and L. rhamnosus for strengthening gut barrier integrity. This comprehensive blend works alongside the digestive enzymes and prebiotic inulin to create optimal conditions for digestive health and immune function.

• Inulin (Fructooligosaccharides) - 200mg

  Inulin provides prebiotic fiber that serves as fuel for beneficial bacteria in the gut, supporting the growth of Bifidobacteria and Lactobacilli while promoting the production of beneficial short-chain fatty acids. This fermentable compound helps maintain optimal gut barrier function and supports healthy inflammatory responses throughout the digestive tract.^[18] At 200mg, this dose provides meaningful prebiotic support that complements the probiotic blend for comprehensive digestive health optimization.

Omega-3 Cardiovascular Support

Essential fatty acids support heart health, brain function, and systemic inflammation control:

• Fish Oil - 700mg (360mg EPA, 240mg DHA)

  

  Fish oil provides the essential omega-3 fatty acids EPA and DHA from pure Peruvian anchovy oil, delivering cardiovascular and cognitive support in an optimal 1.5:1 EPA-to-DHA ratio. The 360mg EPA primarily supports healthy inflammatory responses and cardiovascular function, while the 240mg DHA concentrates in brain tissue to support cognitive performance and neuronal health.^[19] Natural tocopherols are included to protect these delicate fatty acids from oxidation, ensuring maximum potency and bioavailability for long-term cardiovascular and brain health optimization.

  Natural Tocopherols are also included for antioxidant protection of the delicate omega-3 fatty acids.

  The 1.5:1 EPA to DHA ratio supports both cardiovascular health and cognitive function, making this an ideal daily maintenance dose for most adults.

Cellular Longevity Complex

The most advanced component targets cellular aging at its source:

• Setria Glutathione - 250mg

  Setria Glutathione provides 250mg of reduced L-glutathione, the body's master antioxidant and primary cellular defense molecule. This premium form from Kyowa Hakko is the first glutathione clinically demonstrated to raise blood glutathione levels through oral supplementation.^[20]

  Glutathione functions as the cornerstone of cellular detoxification, neutralizing free radicals while supporting immune system function through enhanced T-cell lymphocyte activity and natural killer (NK) cell production. At 250mg daily, this dose provides meaningful support for cellular longevity and oxidative stress defense, making it the foundation of this comprehensive cellular health formula.

• MitoPrime L-Ergothioneine - 5mg

  

  MitoPrime delivers L-ergothioneine, an amino acid antioxidant that functions as a targeted mitochondrial protector with unique storage capabilities. Unlike other antioxidants that work temporarily, ergothioneine accumulates in tissues via specialized OCTN1 transporters and remains on standby until cellular stress demands intervention.^[21] Research demonstrates that ergothioneine accumulates specifically in mitochondria, where it scavenges reactive oxygen species while supporting cellular energy production and protecting mitochondrial DNA from oxidative damage. At 5mg, this dose provides meaningful daily support for cellular longevity and mitochondrial health optimization as part of this comprehensive longevity system.

• Yüth Spermidine - 3mg

  Spermidine serves as the cellular longevity catalyst in this advanced formula, delivering 3mg of this naturally-occurring polyamine that declines with age. Unlike fasting protocols that can be difficult to maintain, spermidine supplementation provides a practical approach to activating autophagy, which is the cellular cleanup process that removes damaged components and promotes cellular renewal.^[22]

  This compound works through epigenetic mechanisms, inhibiting histone acetyltransferases to promote the expression of autophagy-related genes while supporting healthy inflammatory responses throughout the body. Research demonstrates that spermidine extends lifespan across multiple species while improving age-related functional decline, making it a cornerstone ingredient for those seeking to optimize cellular health and longevity at the most fundamental level.

  PQQ (Pyrroloquinoline Quinone) - 20mg supports mitochondrial biogenesis and energy production at the cellular level.

  Now that's a vitamin pack!

How to Use Longevity Multi

Unmatched Supps Longevity Test targets testosterone optimization through 8 clinically-dosed ingredients. KSM-66 Ashwagandha, Furosap, Tongkat Ali, and apigenin work together to support natural test production while managing cortisol and estrogen.

The Longevity Multi system is designed for daily use with your morning routine:

Take one packet (7 capsules/softgels total) with water and food for optimal absorption. The system is formulated to be taken together, allowing the various components to work synergistically throughout the day.

Important Notes:

• Take with food to enhance absorption and minimize any potential digestive upset
• The B-vitamins may cause bright yellow urine - this is normal and expected
• If you're sensitive to supplements, you may start by using half of the packet in the morning, and the other half at night
• Store in a cool, dry place to maintain potency

Consistency is key for long-term benefits. While some effects may be noticed within days to weeks, the full spectrum of longevity benefits develops over months of consistent use.

Conclusion: The Future of Comprehensive Health Support

The Unmatched Supps Longevity Multi is a nuclear bomb compared to what we normally see in daily multivitamin supplementation. Rather than accepting the limitations of single-capsule multivitamins, this system provides the space and specificity needed for truly effective dosing across all major health categories.

The Unmatched 2SHRED System offers stimulant-free 24-hour weight management with separate AM/PM formulas. Founded by Kris Gethin and Doug Miller, this system works around the clock without artificial ingredients.

This massive formulation approach aligns perfectly with the Unmatched philosophy we've seen in their other recent products. Just as Longevity Test addressed hormonal optimization through multiple pathways, and the 2SHRED system revolutionized weight management with targeted AM/PM formulas, the Longevity Multi tackles the complexity of total wellness with the attention to detail that effective supplementation demands.

For those serious about optimizing both immediate performance and long-term health span, this system provides the foundation that makes everything else possible. When your cellular health, cognitive function, joint mobility, liver detoxification, digestive health, cardiovascular system, and foundational nutrition are all optimized, you create the conditions for sustained vitality and longevity.

As Kris Gethin and Doug Miller continue to push the boundaries of what's possible in sports nutrition and longevity, the Longevity Multi stands as their most ambitious and comprehensive offering yet. This is supplementation for those who refuse to compromise on their health optimization journey.