Revive MD Men’s Health: Not Your Traditional Testosterone Supplement

Revive MD

Supplements formulated to optimize your health! See them all on our Revive MD page on PricePlow.

Revive MD has been one of the most promising and intelligent supplement brands to watch, given their incredibly well-formulated health-specific supplements. We’ve recently covered Revive MD’s BRAIN+ daily focus enhancer, their GI+ gut health supplement, and many more listed on our Revive MD news page.

But now it’s time to get back to the team’s bread and butter: men’s health.

Revive MD Men’s Health: A well-rounded men’s formula

When we interviewed Revive’s co-founder Dr. Domenic Iacovone in Episode #042 of the PricePlow Podcast, he explained how they were going to bring a major focus to lab work and results. He came through with a free blood testing initiative for Revive MD customers, and alongside Matt Jansen, the team is now adding to their arsenal of supplements to improve that blood work – with the approval of Chris Bumstead right on the bottle.

Revive MD Men's Health

More than just a testosterone booster – it’s Revive MD Men’s Health, and it’s only two capsules to add to your multi!

With Revive MD Men’s Health, you get a well-rounded, doctor-formulated that can help with testosterone, but doesn’t only focus on it. This supplement can improve the following metrics:

  • Healthy testosterone increase
  • Male sexual health
  • Better estrogen metabolism
  • Efficient prostate function

It can be stacked with any number of Revive MD’s other supplements, depending on your current health situation. New in Men’s Health is an ingredient named Tesnor, based upon pomegranate and cocoa extracts.

We get into the details and the research behind the six ingredients below, but after our PricePlow-driven deals and Revive MD alert sign ups:

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Revive MD Men’s Health Ingredients

Revive’s Men’s Health only requires two capsules to get the following:

  • Tesnor [proprietary blend of pomegranate extract (peel) and cocoa extract (bean)] – 400 mg

    Revive MD Men's Health Ingredients

    Revive MD Men’s Health Ingredients – a solid boost in just two capsules!

    We’ve long known that there are several benefits to both pomegranate and cocoa, ranging from improved recovery from pomegranate[1] to numerous metabolic and physical improvements in cocoa (even myostatin inhibition).[2] The question is, what you extract from these plants, and what properties you want to exert.

    While we don’t know the exact constituents of Tesnor, a proprietary blend of pomegranate peel and cocoa bean extracts, we do have some internal human trials from the manufacturer.

    Tesnor is marketed as a standardized testosterone-boosting extract that boosts in-cell testosterone production while inhibiting aromatase activity. Internal studies from the manufacturer have shown it both improving muscle growth in young males while significantly improving age-related metrics in older males.

    Below we cover the two studies on the ingredient, but it’s worth noting that we don’t yet see them published in any peer-reviewed journal:

    • Study 1: 200mg and 400mg Tesnor improve free testosterone in young males

      Researchers split 120 young males (21-35 years old) into three groups, giving them the following doses for 56 days:[3]

      • 200 mg Tesnor
      • 400 mg Tesnor
      • Placebo
      Tesnor Testosterone

      Towards the end of the trial, Tesnor really started kicking in, especially at 400 mg.[3] This means you may need to run two bottles of Men’s Health.

      Both Tesnor groups had significant increases in free testosterone, grip strength, and muscle growth.[3] The researchers postulated that the ingredient lowered cortisol levels and reduced conversion of testosterone to estradiol.

      They saw no significant changes in vital signs or other concerning biochemical markers and the ingredient was well-tolerated.

      If these results can be replicated, this is incredible news, because boosting testosterone in men that aren’t elderly or unhealthy is a far greater challenge!

    • Study 2: 200mg and 400mg Tesnor improve free and total testosterone in older males

      Another randomized, double-blinded, placebo-controlled study was performed on 120 healthy middle-aged males (aged 36-55) for 56 days. They were again split into three groups:[3]

      • 200 mg Tesnor
      • 400 mg Tesnor
      • Placebo

      ‍ After 56 days, both Tesnor groups had increased free and total testosterone levels and “enhanced anabolic changes”.[3]

    While we would love to see these trials published in public journals, we are believers in both cocoa and pomegranate extracts, and think this could be a solid up-and-coming ingredient when a bit more information is shared. Our theory is that the cocoa is providing blood flow improvements, while the pomegranate is providing the hormonal modulation – making for a solid one-two punch.

  • Saw Palmetto extract (berry) 4:1 – 320 mg

    Revive MD Free Blood Testing

    Revive MD is now offering free blood tests to customers!

    Saw Palmetto is a type of palm tree found in the southern US, and its berries are often used for prostate support supplements, thanks to the great research behind their components.

    Scientifically known as Serenoa repens, it contains a high (95% or more) content of sterols and fatty acids like beta-sitosterol, caprylic acid (C8 MCT), oleic acid, and palmitic acid, as well as many lipases, carotenoids, and tannins that yield great health benefits.[4] We have a solid 4:1 extract here as well.

    Several studies consistently show that supplementing saw palmetto extract can support prostate health (what it’s most known for), but it can also improve urinary tract issues, slow hair loss, increase testosterone levels, and functions as an anti-inflammatory agent.[4-6]

    Saw palmetto meta analysis on 18 studies

    There have been enough studies on saw palmetto that we have access to a very well-performed meta-analysis that combined 18 randomized controlled trials with a total of nearly 3,000 men, ultimately finding that saw palmetto significantly lowers urinary tract symptoms, nighttime urination, and consistently improves peak urinary flow.[7] Going further, when compared to the pharmaceutical drug finasteride, saw palmetto yields similar improvements in urinary tract symptoms and urinary flow — yet with fewer adverse effects reported![7]

    Avoid losing testosterone to DHT!

    Beyond the prostate support, saw palmetto is a potent 5-alpha reductase inhibitor, which is important because this enzyme converts testosterone into DHT (dihydrotestosterone).[4] Not only do we not want to lose our testosterone, but also realize that DHT is largely to blame for hair loss!

    Revive MD Prostate

    Need more prostate support? Revive MD Prostate has three essential minerals to optimize prostate health.

    With saw palmetto, we can do a bit to keep testosterone around and DHT at bay — it’s not bulletproof, but those of us fighting the long (and ultimately losing) fight with hair loss will take any edge we can get for as long as we can before it’s game over.

    Back to urinary tract support, what’s interesting is that the mechanism isn’t fully understood, but it seems rather consistent in terms of getting fewer urinary tract infections.[4] However, there are mixed results on urinary flow,[5] while most are happy that it does reduce nighttime urination.[7]

    Finally, early research suggests that saw palmetto may help reduce prostate cancer cell growth while lowering the severity of benign prostatic hyperplasia (enlarged prostate) symptoms.[5,6] It’s theorized that saw palmetto does this by modulating Cox-2 expression, which is linked to increased prostate cancer risk. However, it’s important to remind you that if you suffer from such conditions, get to your doctor immediately or contact Revive MD to find a clinic.

    If you’re here because you’re interested in prostate support, also see the extraordinarily well-rounded supplement for that very purpose, Revive MD Prostate.

  • Green tea decaffeinated extract (std. to 98% polyphenols) – 200 mg

    Green tea extract is such a well-known metabolic-enhancing ingredient that we sometimes pigeonhole too much into weight loss supplements. Revive MD is wisely pulling it out, since it can act as a “catch all” that provides a slew of benefits relevant to everyone — not just dieters — and it can ultimately lead to improved male performance if diet isn’t too dirty.

    In addition, there are some mechanisms that may interact with our hormones, but they’re not as well-researched as the diet side of the equation.

    Green tea extract: the metabolic catch-all

    Green Tea Catechins

    Green Tea offers multiple powerful catechins, including EGCG. We consider it a “metabolic catch-all” but it may also support hormones a touch too.

    There’s almost too much research to cover it all, but we’ve seen several studies and meta-analyses on green tea drinkers and green tea extracts with following benefits:

    • Increased fat oxidation / decreased fat mass[8]
    • Improved blood flow[9]
    • Better insulin sensitivity[10,11]
    • Lower blood pressure[12]
    • Improved general well-being[12]

    No matter what, these are health improvements that we’ll always take — especially the improved blood flow and insulin sensitivity, which lead to many other health and performance benefits.

    There are several other benefits, but some of the human studies were performed only on women and this is a men’s supplement, so we’re not citing them. On that note, can it help with testosterone? Maybe:

    Green tea’s interactions with hormones

    It’s possible that green tea can inhibit the conversion of testosterone to testosterone glucuronide, leading to more active testosterone at hand.[13] Another animal study showed aromatase inhibition,[14] but the effects don’t seem strong enough for us to really rally around that cry here.

    The long story short is that even if you’re not dieting, you shouldn’t sleep on green tea. There are too many benefits, and it’s a cheap and easy addition.

  • Shoden Ashwagandha (Withania somnifera) extract (root & leaf) (35% withanolides) – 120 mg

    Revive MD Men's Health

    Men’s Health is just for men!

    If you’re looking for a different, stronger ashwagandha extract, then you need to check this one out.

    Also known as withania somnifera, ashwagandha is a popular adaptogenic herb that helps us regulate, adapt, and overcome physical and mental stress through a series of powerful biological mechanisms. But it can do far more than adapt:

    Numerous research trials have concluded that ashwagandha has potent mood-enhancement and cortisol-reduction properties,[15-18] which is great for any man whose stress is keeping them off their game.

    Other extracts need larger doses

    With a plethora of research, mostly relating to its cortisol reduction, ashwagandha has become an extremely popular ingredient in the overall supplement industry. There are several well-known extracts, the most common one being KSM-66. In fact, Revive MD already has Revive MD Ashwagandha, a standalone supplement that has a 600mg clinical dose of KSM-66.

    In our article titled Revive MD Ashwagandha: Combat Stress with KSM-66, we focus on an impressive study that was performed on young and healthy males (not elderly, infertile, hypogonadal, or otherwise unwell individuals), and they still got a 15% boost in testosterone in just eight weeks with 600mg ashwagandha![19]

    KSM-66, however, has 2.5 and 5% standardizations. With less space in a multi-ingredient supplement like Men’s Health, can we go stronger? The answer is yes.

    In the world of ashwagandha, there’s a new contender taking the industry by storm: Shoden.

    Shoden: 35% extract standardization?!

    Shoden is a powerful and unique ashwagandha extract standardized to an impressive 35 withanolides[15] – the highest standardization we’ve seen!

    The Shoden study

    In 2019, researchers published a double-blinded, randomized, placebo-controlled, crossover study using Shoden to test hormones, vigor, and fatigue in men 40-70 years old.[15]

    PricePlow Podcast Dr. Domenic Iacovone Revive MD

    Revive MD comes out swinging in 2021!

    After 16 weeks, the researchers found that Shoden significantly increased both testosterone and DHEA-S levels compared to placebo.[15] Low testosterone levels have a plethora of health consequences, including decreased metabolism, less muscle mass, lower bone density, poor sexual function, deteriorating cardiovascular function, worse brain health, and even increased morbidity. Ashwagandha has consistently shown to improve these areas, and Shoden may just be the most powerful way to do it yet.

    If you want more Ashwagandha, you can always get it from Revive – but for many of us, this is all you need.

  • DIM (Diindolylmethane) – 100 mg

    We often see 3,3′ diindolylmethane (DIM) in both men’s and women’s health formulas because of its hormonal balance benefits – DIM is used to suppress elevated levels of estrogen.

    Realize that this isn’t an “estrogen blocker” – that is only true to an extent. Diindolylmethane doesn’t completely eradicate estrogen from the body, but it does ensure that estrogen levels don’t get too high. DIM mainly functions as an aromatase inhibitor as well as a 5a-reductase inhibitor, and both of these enzymes are involved in the production of estrogen.[20]

    Balancing “good” and “bad” estrogen

    Research has shown that DIM can reduce levels of 16-alpha-hydroxy estrone (“bad estrogen”) while enhancing estradiol 2-hydroxylase (EH) levels (“good estrogen”).[21] This balancing can yield several beneficial effects in terms of mood and physical disposition.

    I3C / DIM Estrogen Metabolites

    Estrogen metabolites. Image courtesy HLHT

    On top of mood problems, when males are faced with too much estrogen, they can deal with gynecomastia, infertility, and erectile dysfunction. Estrogen is necessary, and we’re not trying to knock it to zero, but we do want to keep it under control.

    Finally, there is a series of research showing that diindolylmethane’s anti-estrogenic effects may also reduce the risk of thyroid proliferative disease and breast cancer (which is obviously more common in women but worth stating here).[22,23] In 2016, a systematic review was published showing DIM’s cancer-combating properties, and the researchers attributed that to its estrogen metabolism improvements, the ability to alter apoptosis, and a better oxidative stress response.[23]

  • Boron (as boron glycinate) – 10 mg

    To top off the Men’s Health formula, we have 10mg boron coming from boron glycinate, a simple and easy add-on that shouldn’t be overlooked by men. Boron is critical for bone growth/maintenance, cognition, and wound healing… but more importantly, it enhances the body’s production and utilization of hormones such as testosterone, vitamin D, and estrogen.[24]

    Free testosterone increase!

    3,3'-Diindolylmethane (DIM)

    Balance your estrogen? Even the diindolylmethane (DIM) molecule is balanced!

    In 2011, researchers published a study that showed boron significantly boosted free testosterone levels and also reduced estrogen levels.[25] It’s worth noting that the study was small, with just 8 participants, and we always want more data. On the other hand, there’s no reason not to include it in a men’s formula.

    In addition, boron can help prevent vitamin D deficiency, and it does this by lengthening the vitamin’s half-life and improving magnesium absorption.[25]

    We’ll leave it with the researcher who titled her paper, “Nothing Boring About Boron”.[24]

Dosing

Just two capsules taken once daily. You can take it whenever you take your multivitamin or other supplements.

Men’s Health: for the middle aged guys but Chris Bumstead Approved

Men's Health Chris Bumstead

Men’s Health is Chris Bumstead approved!

Last month, we covered another testosterone-boosting supplement, Raw TEST, made by Revive MD’s “brother brand” Raw Nutrition. That formula had a few more aggressive, cutting-edge ingredients with less human clinical research (alongside several trusted ingredients like ashwagandha). That can be stacked together with Men’s Health here, just note that there would be some overlap in ingredients like boron.

However, for men looking for a more refined, tested, and well-rounded men’s supplement that’s not just for testosterone and libido, Men’s Health is the Revive MD way of doing things. We’re excited to see a new ingredient in Tesnor, and love the effects of Shoden.

One last thing worth noting is that we have the blue “CBum” checkmark and signature, which marks that this is a Chris Bumstead approved supplement. We interviewed Chris last year and definitely worth a read, so click the link above. If Chris is down, then that’s a great sign!

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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References

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  2. Roberto, Mike; “Epicatechin – The Dark Force Behind Dark Chocolate”; The PricePlow Blog; January 8, 2015; https://blog.priceplow.com/epicatechin
  3. Gencor; “Tesnor Herbal Testosterone Boosting Formulation”; https://web.archive.org/web/20210618105704/
  4. Murugusundram S.; “Serenoa Repens: Does It have Any Role in the Management of Androgenetic Alopecia?”;J Cutan Aesthet Surg. 2009;2(1):31–32; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840915/
  5. Gerber GS, et al.; “Randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms.”; Urology. 2001;58(6):960‐965. doi:10.1016/s0090-4295(01)01442-x; https://pubmed.ncbi.nlm.nih.gov/11744467/
  6. Goldmann WH, et al.; “Saw palmetto berry extract inhibits cell growth and Cox-2 expression in prostatic cancer cells.”; Cell Biol Int. 2001;25(11):1117‐1124. doi:10.1006/cbir.2001.0779; https://pubmed.ncbi.nlm.nih.gov/11913955/
  7. Wilt TJ, et al.; “Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review.”; [published correction appears in JAMA 1999 Feb 10;281(6):515]. JAMA. 1998;280(18):1604‐1609. doi:10.1001/jama.280.18.1604; https://pubmed.ncbi.nlm.nih.gov/9820264/
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  9. Ras, Rouyanne T., et al. “Tea Consumption Enhances Endothelial-Dependent Vasodilation; a Meta-Analysis.” PLoS ONE, vol. 6, no. 3, 4 Mar. 2011, p. e16974, 10.1371/journal.pone.0016974; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048861/
  10. Hsu, Chung-Hua, et al. “Does Supplementation with Green Tea Extract Improve Insulin Resistance in Obese Type 2 Diabetics? A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial.” Alternative Medicine Review: A Journal of Clinical Therapeutic, vol. 16, no. 2, 1 June 2011, pp. 157–163; https://pubmed.ncbi.nlm.nih.gov/21649457/ (full text PDF)
  11. Venables, Michelle C, et al. “Green Tea Extract Ingestion, Fat Oxidation, and Glucose Tolerance in Healthy Humans.” The American Journal of Clinical Nutrition, vol. 87, no. 3, 1 Mar. 2008, pp. 778–784, 10.1093/ajcn/87.3.778; https://academic.oup.com/ajcn/article/87/3/778/4633440
  12. Brown, A. Louise, et al. “Effects of Dietary Supplementation with the Green Tea Polyphenol Epigallocatechin-3-Gallate on Insulin Resistance and Associated Metabolic Risk Factors: Randomized Controlled Trial.” British Journal of Nutrition, vol. 101, no. 6, 19 Aug. 2008, pp. 886–894, 10.1017/s0007114508047727; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819662/
  13. Jenkinson, Carl, et al. “Dietary Green and White Teas Suppress UDP-Glucuronosyltransferase UGT2B17 Mediated Testosterone Glucuronidation.” Steroids, vol. 77, no. 6, May 2012, pp. 691–695, 10.1016/j.steroids.2012.02.023; https://pubmed.ncbi.nlm.nih.gov/22429924/
  14. Satoh, K., et al. “Inhibition of Aromatase Activity by Green Tea Extract Catechins and Their Endocrinological Effects of Oral Administration in Rats.” Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, vol. 40, no. 7, 1 July 2002, pp. 925–933, 10.1016/s0278-6915(02)00066-2; https://pubmed.ncbi.nlm.nih.gov/12065214/
  15. Lopresti, Adrian L et al. “An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.”; Medicine vol. 98,37 (2019): e17186; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/
  16. Chandrasekhar, K et al. “A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.” Indian journal of psychological medicine vol. 34,3 (2012): 255-62; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/
  17. Andrade C, Aswath A, Chaturvedi SK, et al. “A double-blind, placebo-controlled evaluation of the anxiolytic efficacy of an ethanolic extract of withania somnifera”; Indian J Psychiatry 2000;42:295–301; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958355/
  18. Auddy B, Hazra J, Mitra A, et al. A standardized Withania Somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study. J Am Nutraceut Assoc 2008;11:50–6; https://www.semanticscholar.org/paper/A-Standardized-Withania-Somnifera-Extract-Reduces-A-Auddy-Hazra/46bdaebfcf4f00730ad217fd6bb88228964e4c2e
  19. Wankhede, Sachin, et al. Nov. 2015. “Examining the Effect of Withania Somnifera Supplementation on Muscle Strength and Recovery: A Randomized Controlled Trial.” Journal of the International Society of Sports Nutrition vol. 12 43; 25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658772/
  20. Balunas, M. et al. Aug. 2008. “Natural Products as Aromatase Inhibitors.” Anti-cancer Agents in Medicinal Chemistry vol. 8,6; 646-82. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074486/
  21. Jellinck, P. et al. Mar. 1993. “Ah Receptor Binding Properties of Indole Carbinols and Induction of Hepatic Estradiol Hydroxylation.” Biochemical Pharmacology vol. 45,5; 1129-36. https://pubmed.ncbi.nlm.nih.gov/8384853
  22. Rajoria, S. et al. Mar. 2011. “3,3′-Diindolylmethane Modulates Estrogen Metabolism in Patients with Thyroid Proliferative Disease: A Pilot Study.” Thyroid vol. 21,3; 299-304. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048776/
  23. Thomson, C. et al. July 2016. “Chemopreventive Properties of 3,3′-Diindolylmethane in Breast Cancer: Evidence From Experimental and Human Studies.” Nutrition Reviews vol. 74,7; 432-43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059820/
  24. Pizzorno, L.; “Nothing Boring About Boron”; Integrative medicine (Encinitas, Calif.) vol. 14,4 (2015): 35-48; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
  25. Naghii MR, et al. “Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines.”; J Trace Elem Med Biol. 2011;25(1):54-58. doi:10.1016/j.jtemb.2010.10.001; https://pubmed.ncbi.nlm.nih.gov/21129941/

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