The first published study on NeuroRush shows that 150mg can enhance working memory accuracy, processing speed, and well-being in healthy adults within hours of consumption.
First peer-reviewed study validates NeuroRush cognitive benefits! 150mg of this coffee arabica extract significantly improved working memory, processing speed & well-being in healthy adults. Coffee's brain power without the jitters.
The supplement industry has been eagerly awaiting peer-reviewed research on NeuroRush, Aura Scientific's coffee arabica extract that's been making waves in nootropics and pre-workout formulas. That wait is finally over.
A new study published in the Journal of Exercise and Nutrition provides the first peer-reviewed validation of NeuroRush's cognitive benefits. The randomized, double-blind, placebo-controlled crossover trial demonstrated that a single 150mg dose can enhance cognitive performance and improve subjective well-being in healthy adults.[1]
This article digs into the study's design, results, and real-world implications. Before heading in, make sure you're signed up for PricePlow's Aura Scientific and NeuroRush news alerts so that you don't miss any other breaking news:
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The Study: Rigorous Research Design Meets Real-World Application
Researchers from Nova Southeastern University conducted a sophisticated crossover trial with 19 healthy adults (mean age 27.8 years) to evaluate NeuroRush's acute effects on cognitive function and mood.[1] The crossover design meant each participant served as their own control, receiving both NeuroRush (150mg) and placebo (150mg maltodextrin) on separate testing visits with a minimum one-week washout period.
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The study employed three validated cognitive tests:
- The Stroop test (measuring attention and cognitive inhibition)
- The N-Back test (evaluating working memory and decision-making)
- The Go/No-Go test (assessing response inhibition)
Participants also completed visual analog scales for mood assessment at baseline and 1, 2, and 3 hours post-ingestion.[1]
The 150mg dose aligns with Aura Scientific's minimum recommended formulation amount and matches what's used in products like ProSupps' Mr. HYDE Infinite, making these findings directly applicable to real-world supplement use.
Key Findings: NeuroRush Delivers Measurable Cognitive Enhancement
The results went well, which isn't surprising to anyone who's used the ingredient:
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Working Memory Gets a Significant Boost
The most impressive results came from the N-Back test, which measures working memory (the cognitive system responsible for temporarily holding and manipulating information). NeuroRush delivered substantial improvements with enhanced accuracy, especially at 1 hour (p = 0.008) but also still going a bit 3 hours post-ingestion (p = 0.091).[1]
Treatment with WCCE significantly improved reaction times and accuracy on cognitive tests.[2]
The 1-hour time point showed a "large effect size" according to Cohen's standards, indicating not just statistical significance but practical relevance. Participants also attempted more responses and processed information faster, suggesting NeuroRush enhances both the speed and accuracy of working memory operations.[1]
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Processing Speed and Attention Benefits
The Stroop test revealed significant improvements in overall cognitive processing. Participants showed enhanced total scores (p = 0.016) and faster reaction times (p = 0.013) across all time points.[1] These improvements indicate better attentional control and cognitive inhibition -- the ability to suppress irrelevant information while focusing on the task at hand.
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Response Time Improvements
The Go/No-Go test showed a trend toward faster overall reaction times in the NeuroRush group (p = 0.080), suggesting improved response efficiency without compromising accuracy.[1]
Mood and Well-Being: The Feel-Good Factor
Beyond cognitive performance, NeuroRush significantly enhanced subjective well-being. At the 3-hour mark, participants reported significantly greater well-being compared to placebo (p = 0.047, effect size d = 0.64).[1]
Notably, well-being scores continued to improve over time within the NeuroRush group, peaking at 3 hours post-ingestion. This time-dependent enhancement suggests that NeuroRush's mood benefits build throughout the day, rather than providing just an immediate boost.
Safety Profile: Well-Tolerated with Cardiovascular Benefits
NeuroRush demonstrated an excellent safety profile throughout the study. All vital signs remained within normal clinical ranges, and the supplement was well-tolerated by all participants.[1]
Interestingly, the NeuroRush group showed some cardiovascular benefits, including lower systolic blood pressure at 1 hour compared to placebo (p = 0.044). These findings align with previous research showing that chlorogenic acids can support healthy blood pressure levels.[1]
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The Science Behind the Results
The researchers attribute NeuroRush's cognitive benefits to its rich content of chlorogenic acids (approximately 53%) and other polyphenols, with minimal caffeine content. This unique profile allows users to experience coffee's cognitive benefits without caffeine-related side effects like jitters or sleep disruption.
Chlorogenic acids cross the blood-brain barrier and provide neuroprotection through multiple mechanisms: reducing oxidative stress, modulating inflammation, and potentially supporting neurotransmitter function. The researchers specifically noted that CGA may enhance cognitive function by lowering reactive oxygen species production and supporting mitochondrial function in the brain.
Clinical Significance: What This Means for Supplement Users
This study provides crucial validation for an ingredient that's been gaining traction in the supplement industry based on promising preliminary data and positive user experiences. The 150mg dose used in the study represents the minimum effective amount recommended by Aura Scientific, suggesting that NeuroRush delivers meaningful cognitive benefits even at conservative doses.
Quick Review: It smells great, and 100 milligrams charges things up... but 200 milligrams is actually intense!
For supplement formulators, these results support NeuroRush's versatility as both a standalone cognitive enhancer and as a synergistic partner with caffeine in pre-workout and nootropic formulations. The ingredient provides an affordable alternative to more expensive cognitive enhancers while delivering measurable benefits.
The study's findings also validate the experiential reports from NeuroRush users who have reported enhanced focus and improved well-being. The time course of effects -- with benefits apparent at 1 hour and continuing through 3 hours -- makes it well-suited for various applications, from morning nootropics to pre-workout supplements.
Study Limitations and Future Research
The researchers acknowledge several limitations: the study was acute (single dose), had a modest sample size of 19 participants, and used a crossover design that may have been affected by practice effects on cognitive tasks.
The authors recommend future studies examine different dosing strategies, including chronic administration and higher doses, to better understand NeuroRush's full potential. Longer-term research will help determine whether these cognitive and mood benefits can be maintained with regular use.
Conclusion: Peer-Reviewed Validation for Coffee's Cognitive Benefits
This first published study on NeuroRush provides excellent evidence that Aura Scientific's coffee seed extract can deliver meaningful cognitive and mood benefits at a practical 150mg dose. The research validates what supplement users have been experiencing: NeuroRush offers a unique way to harness coffee's cognitive benefits without unwanted stimulant effects.
For the supplement industry, this peer-reviewed validation represents a significant milestone for an ingredient that pairs effectively with caffeine while remaining cost-effective compared to other cognitive enhancers. As researchers noted, NeuroRush deserves further research and development -- and based on these promising results, it's likely to get it.
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