Performax Labs HyperMax EXTREME Pre Workout: Downright LOADED

It’s here, and it’s extreme. We’re talking about the next generation pre workout supplement from Performax Labs, HyperMax Extreme.

Performax Labs HyperMax Extreme

The company that takes things to the max is now taking it to the Extreme with HyperMax Extreme!

The HyperMax pre workout series has been through a couple revisions over the years, starting with HyperMax XT and then changing to just “HyperMax” in late 2017, which should remain on the market. But that was nothing like what we have here!

Performax Labs Goes Extreme

After a solid round of beta testing, we can attest that Performax Labs now has their most aggressive and well-dosed pre workout supplement yet. This is the brand who takes things to the max, and they’ve done just that in all the right areas — yet none of the ‘wrong’ ones — with this formula, which comes in the “20/40 2-scoop/1-scoop split”.

The quick HyperMax Extreme notes (in the two-scoop serving):

  • 400mg caffeine!
  • 300mg VASO-6 alongside a monster citrulline dose
  • Quick-hitting PEA + Tyrosine blend
  • Performax Labs

    Performax Labs is not fooling around with this formula. Can you two-scoop it though?!

    Smaller dose of Alpha Yohimbine

The launch is at NaturalBodyInc in New York, and my beta test review and ingredient discussion are below, but first you can check out PricePlow’s prices and sign up for Performax Labs news and deal alerts since the brand slowly and steadily puts out rock star supplements:

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Mike’s official HyperMax Extreme Review

We did a Beta Test (video down below) but you know that we need production tubs for an official review. This one passed with flying colors, and the Orange Mango flavor is the one for sweet tooth lovers:

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Performax Labs’ Best-Tasting Supplement So Far

The taste! This is definitely Performax Labs’ best flavor system job – consider it nearly all raspberry over “Raspberry Lemonade”, which I loved (not a citrus guy). With all the stimulants they use, this is no simple feat and they’ve been getting better and better with it.

However, in the review above, Orange Mango beat even our impressions of raspberry lemonade!! Two great choices depending on if you want it aggressively sweet or more mild.

The Hypermax Labs Extreme Ingredients

As mentioned in the intro, this is a 2-scoop serving with 20 full servings per container. Each scoop weighs 8.5g, so you have a 17g serving size. Due to the stimulant dosage, many will land at 1.5 scoops, but that’s up to how extreme you want to take things:

  • Extreme Pumps and NO

    • L-Citrulline (6g)

      Performax Labs HyperMax Extreme Ingredients

      The Performax Labs HyperMax Extreme Ingredients have a serious amount of stim and a serious amount of pump!

      Wow! No messing around with “citrulline malate” here, Performax Labs hypes the pump machine up with a whopping 6g dose of straight L-Citrulline!!

      Citrulline is a precursor to arginine – ingesting the former gives you more of the latter. And that’s important because arginine leads to nitric oxide production. And as we’ve discussed several times on this site, citrulline supplementation beats arginine supplementation because arginine has poor bioavailability and gets broken down by arginase in the gastrointestinal tract.[1] You can skip that with L-citrulline!

      So we get a ton more NO production here — what’s the point? Well this most excellent molecule relaxes the vasculature and allows more blood to flow… and you know what that means — pumps! In turn (and possibly from other beneficial mechanisms), this may improve recovery, increase nutrient uptake, improve oxygen utilization during exercise, reduce fatigue, and even reduce soreness.[2-5]

      VASO-6 Vasodilation

      Oh it’s coming…. stay tuned for the next-generation pump ingredient in HyperMax Extreme!

      As for the dose.. yeah we’re starting with a bang here. 3g of citrulline and 6g of citrulline malate are the clinical doses, which means we are at double clinical here and if you want to just do a single scoop to keep caffeine (and costs) lower, you’re still in excellent pump territory here!!

      Now that’s how you start a supplement off.

    • Agmatine Sulfate (1g)

      Not done with pumps yet… not even close. To keep nitric oxide levels elevated, Performax Labs prolongs the pumps with agmatine sulfate.

      We like to call this “playing defense” with nitric oxide, since this one is a bit more indirect — agmatine prevents the breakdown of arginine since it inhibits the enzyme responsible for arginine breakdown known as arginase.[6,7]

      As for the dose, another fantastic one. 500mg is the ‘starter dose’, and we get that in just one scoop.

    • VASO6 (gallete-enhanced oligomers) (300mg)

      Now it’s time for the new member of the Performax Labs family: none other than VASO-6! Sold by Compound Solutions, VASO-6 is an extraction of six components from green tea leaves (also found in grape seed) that yield one epic nitric oxide booster, leading to the benefits discussed above.

      VASO-6 HyperMax Extreme

      Two of our favorite companies getting together? A match made in heaven!

      One of those benefits is of course enhanced blood flow, but there’s also data showing it may improve glucose uptake and even muscle protein synthesis due to those NO-boosting benefits![8,9]

      It gets better. VASO-6 could improve recovery via interactions with nitric oxide synthase, which is the protein responsible for your own nitric oxide production (endogenous NO). VASO-6 also includes epicatechins, which could lead to enhanced recovery from some epicatechin content,[10-13] although it’s important to note that this ingredient has a unique galloylated form of them. This is the process where gallic acid is added (galloylation), and this apparently boosts the biological activity!

      Long story short, one study showed that these constituents improved relaxation of the vasculature (endothelial-dependent) 15% more than a control group.[14,15] When it comes to blood flow, 15% is a huge number.

  • Extreme Performance and Endurance

    • Beta Alanine (3.2g)

      Most users will know beta alanine at this point, but what’s funny is that a full scoop of the regular HyperMax had 3g — just short of the typical clinical daily dose of 3.2g. Performax Labs takes it EXTREME with the extra 0.2g to get us to daily clinical doses!*

      Beta Alanine Boosts Exercise Performance

      Beta Alanine Boosts Exercise Performance when taken 3.2g per day (but that was split amongst four separate doses)

      Beta alanine increases of skeletal muscle carnosine concentration, and thanks to that, it has demonstrated an increase in athletic performance,[16] increased work capacity,[17] reduced fatigue,[18] and increased peak power output.[19]

      The carnosine produced protects from lactic acid build-up — it acts as a buffer during exercise bouts,[20] especially in the bouts that are about 1-4 minutes long. This makes it a muscular endurance-enhancer,[20,21] and if you’re hitting enough volume, we posit that it can indirectly help you reduce body fat thanks to more training capacity.[22]

      *Note that in the studies cited, those doses were typically spread throughout the day, so there is some discrepancy, but we just like to keep things at saturation and slamming 3.2g per day seems like a convenient and viable way to do that.

    • Betaine Anhydrous (2.5g)

      Trimethylglycine

      From the MEN’s study: The arms don’t lie! Here’s one place where placebo doesn’t rule: arm size! Betaine built bigger arms… in trained subjects![25]

      Another clinical dose! Betaine is popular in many pre workouts, and on top of the muscle gains, strength boost, and fat loss studies we’re about to cite, we posit that it helps with pumps as well!

      Betaine is an osmolyte, which means it helps your body transfer water between cells. This leads to endurance and power output based benefits.[23] We believe that you’ll feel added pumps if you drink plenty of water with this as well.

      But it goes beyond water — betaine has also been shown to increase muscle protein synthesis![24] This works in a manner similar to creatine, but we still recommend getting both in to be sure.

      Fat loss effects too

      A study performed by Jason Cholewa showed clinical gains in men at 2.5g per day,[25] and more recently in 2018, he published a follow-up study showing fat loss and performance increases in women too![26]

  • Extreme Focus and Mood

    Note: Because of the next three ingredients, HyperMax Extreme should never be used with prescription drugs such as SSRIs. As always, speak to your doctor before starting any new diet or supplementation program!

    • B-Phenylethylamine HCl (400mg)

      Performax Labs StimMax Coming Soon

      If this isn’t enough stims for you, we’re not sure what to do, but StimMax could be the answer!

      Here’s our first form of PEA, straight Beta-Phenylethylamine. This is the kickstarter for the feel-good, euphoric effects in HyperMax Extreme, and is a fantastic “engine starter” inside. When you take PEA, it quickly helps the body release more catecholamines, providing a feel-good sensation.[27]

      The major issue is that it wears off quickly (your monoamine oxidase (MAO) enzyme will cleave it off the dopamine receptor and quickly break it down). Good news – there are two counters to that here, and they’re in the form of the next two ingredients, an advanced form of PEA and hordenine, which will prolong the PEA rush.

    • N,N-Dimethylphenethylamine Citrate (250mg)

      To augment the straight PEA trace amine above, We have N,N-Phenethyldimethylamine Citrate, an “advanced” form PEA. This feel-good stimulant adds to the mood boost that we experienced when taking HyperMax Extreme, which is unsurprising given this is what PEA type molecules do.[27]

      Compare:

      PEA 2D Structure has no receptor protection

      The PEA molecule offers practically no physical protection for the amine (N), so MAO has no problem “cleaving” it into less relevant components

      N-Phenethyldimethylamine 2D Receptor with Protection Highlighted

      N-Phenethyldimethylamine is like a PEA molecule, but with an N,N’ Alkyl section that also prevents MAO from cleaving it… meaning a longer-lasting euphoric ‘buzz’ than regular PEA

      Where it’s different is that it has two alkyl groups attached to the PEA backbone, which physically keeps it from getting broken down as quickly by the aforementioned MAO enzyme. This keeps the ‘pop’ going longer and stronger, and when it’s combined with PEA above, we get a crazy good two-phase burst.

      If you’re a fan of Performax Labs stimulant-based supplements, then you’re no doubt a fan of this ingredient, because it’s in nearly every stim-based product here. So there’s zero surprise they’ve included it. Performax does not add other ‘exotic’ stimulants on top of it – they’ve been riding the “NDPEA” train since nearly the beginning!

    • Hordenine HCl (60mg)

      Performax Labs Get Hyped

      Get Hyped!

      As alluded to above, we need something to keep our PEA-based boost going a bit longer. Can we “downtune” the MAO enzyme?

      The answer is yes, with hordenine. This is an ingredient that works on multiple angles, and as you can imagine, the first is that it acts as an MAO inhibitor.[29,30] By inhibiting the MAO enzyme, it prolongs the mood-boosting PEA compounds up above. This can turn into even more increased “sense of wellness”, mood, and general good vibes!

      But to top it off, it also behaves like a beta-2 adrenergic receptor agonist,[31] which means it may free fatty acids that your body can use as a fuel source. Fat burning, energy, and ingredient enhancement? Perfect.

      50mg is usually the standard dose of hordenine, but Performax Labs of course had to go a bit extreme here!

  • Extreme Energy and Drive

    • L-Tyrosine (1g)

      Tyrosine Plasma Elevations

      Fig.3A-D. Increased neurotransmitter biosynthesis in five PKU patients after supplementation of unrestricted diet with tyrosine. Dietary tyrosine supplement increases plasma tyrosine (A), which in turn increases CSF tyrosine (B). Enhancements of dopamine bio-synthesis as estimated fi’om HVA concentration in CSF correlate with CSF tyrosine (C), Increases in the biosynthesis of dopamine and serotonin as measured by increased CSF concentrations of HVA and 5-HIAA correlate with dietary tyrosine supplement (D). (0) unrestricted diet; (~) unrestricted diet supplemented with tyrosine.

      More euphoria and focus? Yes! Tyrosine is a precursor to the catecholamines,[32] which include ‘energetic’ neurotransmitters such as epinephrine, dopamine, and norepinephrine.

      We have a one-two punch coming here — tyrosine boosts catecholamine production, and then caffeine also encourages the system to release more of them into into systemic circulation. This means more production and more release. Ultimately you’re left with yet another feel-good combo,[33] something Performax Labs is great at.

      What’s ironic given the profile above is that some research showed a reduction in stress from it![34] So for whatever reason, tyrosine seems to help very stressed individuals… perhaps they’re just not getting enough and need added catecholamine production.

      1g is no slouch of a dose either!

    • Caffeine Anhydrous (400mg)

      And now for the legendary stimulant, none other than caffeine. 400mg is a serious dose, and will likely be what controls you between one and two scoops. We landed at just under 1.5 scoops, consistent with the 250-300mg caffeine we enjoy taking (and there were still plenty of pumps there).

      Caffeine Energy Expenditure

      Caffeine increases energy expenditure by roughly an extra .15 calories per minute. Not huge, but we’ll take it!

      As to the research, there’s a ton of it with caffeine, but it can increase energy expenditure and lipolysis, so you may get a bit of fat burning from it when training. To top it off, it also helps oxidize fatty acids.[35-37]

      Now at this dose, if you can handle two or so scoops, we may be able to see strength gains, as there’s been clinical differences shown at around 5-6mg caffeine per kg body weight![38,39] Extreme!

    • Synephrine HCl (50mg)

      Synephrine is another beta agonist with some similar properties to Hordenine above, but it seems to be stronger with those regards. It’s found in Bitter Orange, and actually has a similar structure to ephedrine! However, due to its differences, it’s been proven to be much milder (and thus more safely tolerated) at similar doses.[40]

      It actually acts as both a Beta-2 and Beta-3 adrenergic receptor agonist, which means it helps free stored fatty acids and gets them released into the bloodstream for use — which is why it’s great to take preworkout![41]

    • Rauwolfia Vomitoria Extract (2mg)

      HyperMax Extreme

      This bad boy’s so extreme, we need more flames

      And last but certainly not least, Rauwolfia Vomitoria Extract, standardized for Alpha Yohimbine. The label doesn’t state such, but usually this is a 90% extract, so we’re thinking this is really a bit less than 2mg in the two scoop dose. This is actually less than the original HyperMax, which we think is a smart play – this dose range is closer to where we like it.

      “Alpha Yo”, as we affectionately call it is an alkaloid that brings an intense adrenaline-releasing effect, and getting the dose right is key. We landed on 1.5 scoops mainly because of this ingredient, where the positive effects were felt but none of the anxiousness that can come when taking too much.

      This ingredient is like yohimbine… but “enhanced”. Its molecule has a different orientation than yohimbine,[42] and seems to bind better. It acts as an alpha-2 antagonist, reducing the effects of this pathway. By blocking these receptors, you may get fat loss because it helps the body remove fat from adipocytes and prevents further storage.[43]

      What a way to go out!

Now that’s a formula!

Initial Launch Flavors

Performax Labs HyperMax Extreme Preview

Mike got a sneak peak here, and fell in love with the strong raspberry side of this one!

As mentioned in the intro and review, Performax Labs is starting HyperMax Extreme off with Raspberry Lemonade and Orange Mango, two flavors they’re well known for in their latest few releases.

The raspberry lemonade flavor is very heavy on the raspberry side of things, which we personally liked a lot. But in the official review above, it was Orange Mango that had the wow factor!

Mike’s Beta Test HyperMax Extreme Review: Euphoric

Before knowing all of the ingredients, I was honored to be able to participate in Performax Labs’ beta test, and came away with some intense workouts. But the thing I noticed most was the euphoria coming from Hypermax Extreme:

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The PEA blend acts in well under 10 minutes, and I was hit with a wave of quality mood and energy support that got me fired up to train on a low-sleep day. The pumps are exactly what you’d expect from this label – fantastic – but it’s the mood and energy burst that I kept coming back for — consistent with Performax Labs’ other supplements, by the way.

Stacking

You seriously think you need to stack something here?! If anything, you could add some CreMax for the creatine support… but outside of that, you’re looking really good. A good combination to add could be choline and carnitine, but you should be eating plenty of red meat and eggs, and if you are, then you don’t need to worry about those as much.

We honestly don’t think you need much more in the way of pumps either. But if you’re nuts, you can always go with VasoMax, which actually provides plenty of GlycerPump glycerol (not in HyperMax Extreme) as well as choline from Alpha-GPC, also not in here. GlycerMax is another cost-effective option that’s just GlycerPump solo.

Performax Labs Goes Extreme

What an aggressive pre workout supplement. As always, Performax Labs takes things to the max, and basically goes as hard as you can go without using DM*A ingredients.

We are huge fans of StimMax, which puts us at “perfect cruising altitude”, and HyperMax Extreme takes much of the intense stimulation from that and adds a whole truckload of pumps, endurance boosters, and ergogenics. What more could you ask for?

Performax Labs

See all of Performax Labs‘ well-formulated products. This is a brand with brains, and that’s why we love them.

The biggest question is where you’ll land dosage-wise. We ended up at 1.5, but if you can rock out two whole scoops, you’re going to be training on another planet, with strength gains from even the caffeine, let alone everything else like a ridiculous citrulline dose or VASO-6.

Performax Labs lives up to their name, and executed extremely well on an “Extreme”-themed supplement. Are you extreme enough to handle it?

Performax Labs HyperMax Extreme - Deals and Price Drop Alerts

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Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is a biohacker with extensive experience in supplementation and dietary modification, whose personal expertise stems from several "n=1" experiments done on himself.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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