Muscle Elements PreCre XS: Energy Upgraded!

Muscle Elements PreCre XS

Muscle Elements newest pre workout PreCre XS contains 419mg total caffeine in addition to yohimbine making for one seriously high stim pre workout!

Several weeks ago Muscle Elements announced they’d be bringing a newer, more powerful pre workout to the market. This new product is not intended to replace the original PreCre, but serve as another option for the high-stim fiends out there.

We’ve covered the original PreCre in great detail before in a blog post titled PreCre: Everything RIGHT in a Pre Workout. Clearly we love it, as it’s rated one of our top pre workouts and a product we can recommend to nearly anyone, anytime, anywhere!

Now, PreCre XS takes all that is great from its predecessor and jacks up the energy component to level 9000!

PreCre XS Long Story Short:

  • Total Caffeine dose: 419mg!
  • Same pump / ergogenic blend as PreCre Original
  • More focus ingredients
  • Yohimbine and rauwolscine added

We’ll reveal the full label below, but first make sure to sign up for price drop alerts and check the best deal:

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PreCre XS Ingredients

If you were a fan of the original PreCre, you’ll be glad to know that M.e. has carried over everything to PreCre XS. Since the two are so remarkably similar, we’re just going to cover the new components here.

For the full breakdown of the original product, head on over to our original blog post on PreCre.

Now, onto the upgraded stims!

  • Mind-Muscle Activator Elements™

    • N-Acetyl L-Tyrosine (500mg)

      Muscle Elements PreCre XS Ingredients

      PreCre XS contains all the same things you loved from the original PreCre, but with A LOT more energy crammed in!

      Our first ingredient in the new PreCre XS is a carryover from the original PreCre. Both contain 500mg of N-Acetyl L-Tyrosine (NALT) to help improve focus and cognition during your workouts.

      NALT is a more bioavailable form of the amino acid L-Tyrosine, which when supplemented increases the production of two critical neurotransmitters in the body, dopamine and noradrenaline. This helps boost mood and focus, while decreasing stress and anxiety.[1,2]

    • Caffeine Anhydrous (370mg)

      The first of many stims to come is caffeine anhydrous. The original PreCre contained 200mg straight caffeine (plus 44mg from slower sources) while PreCre XS crams in 370mg worth of pure caffeine! Keep in mind, this is only the first of more to come.

      This dose alone elevates PreCre XS into the growing category of 300+mg caffeinated pre  workouts.

      This amount may be great for the 2-3 scooper kind of guys out there. Even so, we’d still start a bit less than a scoop. All that being said, should you be able to handle this amount of caffeine, you should expect to see some great improvements in performance, mood, focus, and endurance.[3,4]

      And if you can’t handle this much caffeine… you should be looking at the Original PreCre anyway!

    • Guarana Extract (200mg)

      Guarana seeds contain roughly twice the amount of caffeine as coffee beans[5] and are typically found in all sorts of energy drinks. The particular extract here is standardized for 22% caffeine, which brings the total caffeine content so far 414mg!

    • Disodium Phosphate (200mg)

      Muscle Elements PreCre XS Unmatched

      PreCre XS boasts a stim profiled unmatched by virtually all competitors on the market. But is it too much stims?

      Much like with NALT, M.e. has kept the electrolyte blend the exact same from PreCre. Lots of electrolytes are lost during high intensity exercise, and even as little as a 2% decrease in hydration levels can lead to severe cramping, reduced performance, and impaired CNS function.[6]

      Sodium is one of the key electrolytes required by the body to perform several key physiological processes, namely muscle contraction and nerve function.

    • Dimagnesium Phosphate (200mg)

      Magnesium is another electrolyte involved in over 300 different processes in the body including protein synthesis, energy production, and muscular contraction.[7,8,9]

      Furthermore, magnesium is also the second most abundant mineral in the body, and the second most common nutrient deficiency in humans.[10,11] For athletes, it’s even more important to maintain adequate magnesium levels in order to ensure optimal performance and recovery.

    • Dicalcium Phosphate (200mg)

      Calcium is our last electrolyte carried over from PreCre XS and a vital player in bone formation and metabolism. Often times, it’s included alongside magnesium, but this may not be ideal as the two minerals compete for the same absorption pathway.

      Between this and the OG PreCre, Muscle Elements guarantees a one-scoop experience for nearly everyone.

      When dosed together, calcium absorption seems to be impaired significantly.[12]

    • DMAE (150mg)

      DMAE (Dimethyl Amino Ethanol Bitartrate) is a derivative of choline that helps prevent the buildup of the “age pigment” in the brain.[13] It’s also frequently used as a focus booster.

      It helps enhance acetylcholine production in the body as well as improve memory and cognition. DMAE really shines though when combined with caffeine and NALT, yielding a very “in the zone” type sensation during your workout.

    • Dicaffeine Malate (70mg)

      Muscle Elements PreCre XS Dark Side

      Is the profile on PreCre XS enough to get you to turn to the dark side?

      Dicaffeine malate is a combination of caffeine anhydrous and malic acid that contains roughly 73% caffeine by weight. This means we now have an additional 51-52mg of caffeine to add to the 370mg already contained in PreCre XS.

      This means that we now have a grand total of 419mg of caffeine!

    • Huperzine A 1% (5mg)

      Huperzine is another cognitive booster, also known as Toothed Clubmoss. While DMAE directly increases levels of acetylcholine, Huperzine indirectly increases it by inhibiting acetylcholinesterase.[14]

      Acetylcholinesterase is the enzyme responsible for degrading acetylcholine in the body. Inhibiting this enzyme means more acetylcholine is around in the body, leading to greater focus.

      Huperzine also prevents premature cell death instigated by the neurotoxin glutamine and may potentially even help create new brain cells, making it neurogenerative.[15,16]

    • Yohimbine HCl 99% (2mg)

      Muscle Elements Priscilla Lucci

      Muscle Elements athlete Priscilla Lucci trains with PreCre, will she step up to PreCre XS?

      Yohimbine is an alpha-2-adrenergic blocking agent derived from the Pausinystalia yohimbe tree. As an alpha receptor agonist, it increases noradrenaline release,[17] and as well as increase alertness and cognition.[18]

      Yohimbine’s best suited for enhancing lipolysis, increasing appetite control and energy expenditure.[19,20,21] Coupled with the caffeine and one additional form of Y to come means you’ll be experiencing an energy and warming overload, most likely never felt before.

    • Rauwolfia Vomitoria Extract (1mg)

      Rauwolfia, a.k.a. alpha-yohimbine, a.k.a. rauwolscine, is final ingredient (and stimulant) in PreCre XS. Whereas yohimbine is naturally found in the bark of the, Pausinystalia yohimbe tree, Rauwolfia is diastereoisomer of yohimbine, basically a slight variant of Y that function more or less the same but with some different properties.

      Much like regular Yohimbine, Alpha-Y functions primarily as an alpha-2 agonist[22], which helps liberate stored fatty acids for use as an energy source by the body.

      Furthermore, rauwolscine has a longer half-life than regular Y which means it’ll hang around longer in your body giving you an even more prolonged energy high.

      Hopefully the ride down isn’t too brutal from the combination of all these stimulants…

Put simply, between this and the OG PreCre, Muscle Elements guarantees a one-scoop experience for nearly everyone.

Initial flavors Available

Unfortunately, as we write this, PreCre XS isn’t available yet, though we do expect it to be released anytime now. Once it is released, we know that it will at least come in Cherry Limeade. As for any additional flavors, we’ll just have to wait and see.

Takeaway

Muscle Elements sure knows how to make things “XS” in terms of energy. Coming in at 470mg of caffeine seems a bit excessive in our minds, in addition to all of the other stimulants contained in PreCre XS.

Now, if you’re a stimulant junky, this may be an ideal option for you. However, if you’re more of a “regular” stim fan and like something in the 200-300mg range, your best bet is to head back to our original PreCre page.

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References

  1. Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
  2. Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
  3. Backhouse, SH, et. al; Appetite; “Caffeine ingestion, affect and perceived exertion during prolonged cycling;” August 2011
  4. Hurley, CF; Journal of Strength and Conditioning Research; “The effect of caffeine ingestion on delayed onset muscle soreness;” November 2013
  5. Lima WP, et al; Lipid metabolism in trained rats: effect of guarana (Paullinia cupana Mart.) supplementation . Clin Nutr. (2005)A quantitative method for the analysis of xanthine alkaloids in Paullinia cupana (guarana) by capillary column gas chromatography
  6. Casa, DJ., Clarkson, PM., Roberts, WO., American College of Sports Medicine Roundtable on Hydration and Physical Activity: Consensus Statements. Current Sports Medicine Reports 2005, 4:115–127
  7. Institute of Medicine (IOM). Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Washington, DC: National Academy Press, 1997.
  8. Rude RK. Magnesium. In: Coates PM, Betz JM, Blackman MR, Cragg GM, Levine M, Moss J, White JD, eds.Encyclopedia of Dietary Supplements. 2nd ed. New York, NY: Informa Healthcare; 2010:527-37.
  9. Stephenson EW, Podolsky RJ; Regulation by magnesium of intracellular calcium movement in skinned muscle fibers . J Gen Physiol. (1977)
  10. Iotti S, Malucelli E; In vivo assessment of Mg2+ in human brain and skeletal muscle by 31P-MRS . Magnes Res. (2008)
  11. Jacka FN, et al; Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study . Aust N Z J Psychiatry. (2009)
  12. Basso LE, et al; Effect of magnesium supplementation on the fractional intestinal absorption of 45CaCl2 in women with a low erythrocyte magnesium concentration . Metabolism. (2000)
  13. Nagy I, Nagy K; On the role of cross-linking of cellular proteins in aging . Mech Ageing Dev. (1980)
  14. Zhao, Q; Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; 2002
  15. http://www.ncbi.nlm.nih.gov/pubmed/9141073
  16. http://www.ncbi.nlm.nih.gov/pubmed/23454433
  17. Szemeredi K, et al; Simultaneous measurement of plasma and brain extracellular fluid concentrations of catechols after yohimbine administration in rats . Brain Res. (1991)
  18. Mizuki Y, et al; Differential effects of noradrenergic drugs on anxiety and arousal in healthy volunteers with high and low anxiety . Prog Neuropsychopharmacol Biol Psychiatry. (1996)
  19. Galitzky J, et al; Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers . Eur J Clin Invest. (1988)
  20. Callahan MF, Beales M, Oltmans GA; Yohimbine and rauwolscine reduce food intake of genetically obese (obob) and lean mice . Pharmacol Biochem Behav. (1984)
  21. Waluga M, et al; Cardiovascular effects of ephedrine, caffeine and yohimbine measured by thoracic electrical bioimpedance in obese women . Clin Physiol. (1998)
  22. Perry BD, U’Prichard DC. (3H)rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. Eur J Pharmacol. (1981)
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