Olympus Labs Ep1logue: An EPIC Dose of Muscle-Building Epicatechin

Olympus Labs has dropped yet another natural muscle builder with their new formulation named EP1logue. Rising above its competition, EP1LOGUE has three fully disclosed, natural ingredients… one of which has an epic dosage. The question of the hour is: will it help lifters make more gains, and if so,how do we best fit it into an athlete’s Olympus Labs stack?

Olympus Labs Ep1logue

Olympus Labs Ep1logue has the most epic dose of Epicatechin we’ve seen!

Like MASSACR3 before it, EP1LOGUE is a product designed to help natural lifters get more gains. Since it’s designed for natural lifters, Olympus Labs stuck with naturally-derived compounds. EP1LOGUE contains a triad of ingredients, making it a tried-and-true “minimalist” formula, which we appreciate for stacking purposes.

The most epic epicatechin supplement to date… with a stacking twist

As our dedicated following may note, EP1LOGUE and MASSACR3 actually have two of the same ingredients! Reason being, Olympus Labs designed these two separate anabolic products that can build on one another in a powerful stack, but you can also pick one over the other if on a budget. By stacking both agents, lifters are given a megadose of the mutual ingredients while also getting to experience the unique characteristics of both formulae.

We break down the ingredients and stacking situation below, but first, take a minute to compare prices and sign up for our Olympus Labs News Alerts with PricePlow:

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EP1LOGUE is a capsule based product, and Olympus Labs got away with a two capsule serving size because of the powerfully-extracted formulation. This means that lifters that take both products discussed above only have to take four capsules a day for their muscle stack, which is nothing compared to some of the stuff non-natty guys have to take!

Now that we know what we’re looking at, let’s get into the science to see if the release of EP1LOGUE is the epilogue of the natural anabolic market.

Olympus Labs Ep1logue Ingredients

  • PhytoFUSE™ Epicatechin – 600mg

    Olympus Labs Ep1logue Ingredients

    Two of these ingredients are the same as in Massacr3, with a monster 600mg epicatechin being the difference. Can you see the super stack?!

    Before we get to the PhytoFUSE™ system, we’ll explain why epicatechin is worth an entire product designed around it. Epicatechin is a molecule found in dark chocolate and green tea, and it turns out that this is one of the major constituents responsible for those news stories talking about the health benefits of dark chocolate. EP1LOGUE derives its epicatechin from green tea. Regarding the health benefits — the best part is that the research has Olympus’ back!

    Epicatechin’s benefits

    Epicatechin may improve strength and muscle building, improve glucose tolerance, produce greater endurance, and may even bolster nitric oxide production.[1-5] You read that correctly — this is a muscle builder that also helps you get a better pump! And if you need even more convincing, VASO-6, perhaps our favorite pump innovation in years, uses a different form of epicatechin below too!

    Beyond the preliminary research, there is a growing body of literature showing that epicatechin may inhibit myostatin.[1,6] Myostatin is the traffic cop of muscle building — it enforces a speed limit for growth. Epicatechin may inhibit myostatin by increasing follistatin. Follistatin is myostatin’s arch nemesis — so more follistatin means less myostatin.[6]

    What is PhytoFUSE?

    How Epicatechin Affects Myostatin Levels

    Epicatechin dropping myostatin! Will it translate to GAINS with hard training? We believe so.

    Now we can discuss PhytoFUSE™ — a powerful system designed to rev up the bioavailability of products. PhytoFuse is based on a compound called soy phosphatidylcholine, a lipid. Soy phosphatidylcholine encapsulation is equivalent to wrapping an extract around in a layer of easy-absorbed fat. As we know (sometimes unfortunately), the intestine loves to absorb lipids, so it absorbs the ingredient hidden in the lipid coat in twine. It’s called a “liposome”, and you can consider it like a “Trojan Horse” method to get more of a non-soluble ingredient into our collective bloodstreams.

    This enhanced bioavailability, when combined with the massive 600mg dose, likely renders EPILOGUE the most effective epicatechin product on the market. We just don’t see doses like this, and definitely not with a liposomal wrapper like this! You heard it here first.

  • VASO-6 (300mg)

    Olympus Labs Ep1logue Benefits

    The Olympus Labs Ep1logue Benefits

    VASO-6 is a complex of six ingredients all derived from green tea leaves. It’s an incredible nitric oxide booster that has to be experienced to be believed. Nitric oxide is a compound we talk about ad nauseam at PricePlow, and for a good reason — it’s the best way to get massive pumps when weight training (and it’s incredibly healthy for cardiovascular function).

    When the body has higher levels of nitric oxide, blood vessels dilate. A dilated vessel allows more blood to flow through it at a time — leading to the great pumps lifters report upon VASO-6 supplementation. The enhanced blood flow may also improve glucose uptake and muscle protein synthesis.[7-8] The boost in blood flow is substantial, with one investigation reporting a 15% increase in endothelial dependent vascular relaxation. 15% is a big number for the vascular system, so the pumps are for real.

    VASO-6 may work by acting on nitric oxide synthase, the enzyme responsible for nitric oxide production in the body. This interaction may lead to heightened recovery — but we wouldn’t be surprised if the recovery benefits come from the epicatechins present in VASO-6. While VASO-6 is at its best before a gym session, the enhanced blood flow on rest days will improve the delivery of the other compounds present in MASSACR3 and EP1LOGUE.

  • UroBolin (150mg)

    VASO-6 Vasodilation

    Charts like this always make us put our skeptical hat on, but after enough use, we’re believers!

    UroBolin, or Urolithin B, is a metabolite of ellagic acid. This is the wild card that we’re so excited about in 2019 and moving forward.

    Urolithin B may improve growth and differentiation of C2C12 myotubes via an increase in protein synthesis. While this sounds like scientific mumbo-jumbo, just know this mechanism of UroBolin suggests it may improve muscle hypertrophy.[9] The same investigation showed that Urolithin B could prevent muscular atrophy. The researchers postulated that urolithin B may change the androgen receptor, and a pathway known as MTORC1, but this connection has yet to be solidified by further investigations.[9]

    UroBolin is a promising ingredient that may be the latest and greatest in terms of muscle building. However, the current research is in vivo and urolithin B has yet to undergo a convincing human trial. Put us down as “optimistically spiteful” about UroBolin’s future.

Dosage, Scheduling, Stacking, And Nit-Picking

Olympus Labs Ep1logue Label

The dosage instructions for Ep1logue are above the facts

Once again supporting out stacking theory, Olympus Labs recommends lifters take EP1LOGUE 30-45 minutes before a workout — just like with MASSACR3. That makes sense, given the nitric oxide boosting capabilities of epicatechin and VASO-6.

On rest days, Olympus Labs recommend that lifters take it on an empty stomach. Taking EL1MINATE on an empty stomach method is there to improve digestion, so we’d take the advice.

Stacking?

Now let‘s talk about some anabolic combinations. The most obvious stack comprises EP1LOGUE and MASSACR3 together, where you’ll get “unheard of” doses of VASO-6 and UroBolin, but also full doses of epicatechin and laxogenin too! The stack would produce some insane pumps — especially if paired with a citrulline-heavy pre workout like I Am Suprem3 Black Magic.

Those that limit their growth because of poor appetite may want to throw K1NGS SLAYER into the mix, as you gotta eat to grow. Remember: eat what you are — muscle tissue. So go to the butcher and get yourself some healthy meat.

Conclusion: The Best Epicatechin Supplement on the Market?

Olympus Labs Ep1logue Features

Not just epic epicatechin, but incredible delivery of these two other ingredients!

EP1LOGUE is now in the running for the best epicatechin formulation on the market. Not only does it seem like a fantastic muscle-builder, but its an incredible workout enhancer and even cardioprotective supplement too!

While Ep1logue does epicatechin better than its competition — it also delivers massive pumps through VASO-6 and even more potential gains through UroBolin, two things we think any epicatechin lover would want to try.

If you’re a natural lifter looking for more gains without turning to prohormones or other more hardcore alternatives (be them legal or not), you’ve come to the EP1LOGUE of your search.

Olympus Labs Ep1logue - Deals and Price Drop Alerts

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Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is a biohacker with extensive experience in supplementation and dietary modification, whose personal expertise stems from several "n=1" experiments done on himself.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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References

  1. Gutierrez-Salmean, G., Ciaraldi, T. P., Nogueira, L., Barboza, J., Taub, P. R., Hogan, M. C., Ramirez-Sanchez, I. (2014); “Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation”; The Journal of Nutritional Biochemistry, 25(1), 91-94; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857584/
  2. Barnett, Christopher F et al; “Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers”; Food & function vol. 6,3 (2015): 824-33; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357542/
  3. Grassi, D; “Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons”; Department of Internal Medicine and Public Health, University of L’Aquila; 2005 http://www.ncbi.nlm.nih.gov/pubmed/15755830
  4. Nogueira, L., Ramirez-Sanchez, I., Perkins, G. A., Murphy, A., Taub, P. R., Ceballos, G., Villarreal, F. J., Hogan, M. C. and Malek, M. H. (2011); “(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle”; The Journal of Physiology, 589: 4615–4631; http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2011.209924/full
  5. Fraga CG, Litterio MC, Prince PD, Calabró V, Piotrkowski B, Galleano M; “Cocoa flavanols: effects on vascular nitric oxide and blood pressure. Journal of Clinical Biochemistry and Nutrition”; 2011; 48(1):63-67; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022066/
  6. Rodino-Klapac, Louise R et al; “Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease”; Muscle & nerve vol. 39,3 (2009): 283-96; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717722/
  7. Lorenz M, Wessler S, Follmann E, et al; “A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation”; J Biol Chem; 2004; 279(7):6190-6195; http://www.jbc.org/content/279/7/6190.full.pdf+html
  8. Kim JA, Formoso G, Li Y, et al; “Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn”; J Biol Chem. 2007; 282(18):13736-13745; http://www.jbc.org/content/282/18/13736.full.pdf+html
  9. Rodriguez J, Pierre N, Naslain D, et al; “Urolithin B, a newly identified regulator of skeletal muscle mass”; J Cachexia Sarcopenia Muscle. 2017;8(4):583-597; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566634/

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