ProSupps Infinite Pre-Workout: Moderate on Caffeine, Big on Everything Else

Published on November 4, 2024 by PricePlow Staff | No Comments

ProSupps is a brand that has earned a reputation for novel and exciting formulas. They’re not afraid of pushing the envelope and using new, promising ingredients in their supplements. After all, the brand targets the serious athlete, and the serious athlete needs to find an edge beyond what everyone else is doing.

ProSupps Infinite Pre-Workout: Moderate on Caffeine, But Big on Everything Else

ProSupps Infinite Pre-Workout keeps caffeine moderate at 280 mg, but goes big with Aura Scientific’s advanced ingredients like EndoFlo and NeuroRush. Backed by a double yohimbe blend, this formula pushes limits with a unique mix designed to enhance performance.

We’ve covered a few of the legendary brand’s formulas in the past, like the ProSupps Thermo fat burner and their new lower-stim Jekyll pre-workout. In both formulas, the brand included ingredients from Aura Scientific – an ingredient manufacturer on the cutting edge of performance formulation.

Whereas Jekyll was a moderate, balanced pre-workout option for those who didn’t want to get over-stimmed, ProSupps also has a high-octane pre-workout built around the same heavy-hitting ingredients – plus, well, a lot more. And this one is not named “Hyde”!

Pro Supps Pro Series: Infinite Pre Workout

Infinite Pre is part of ProSupps’ Pro Series – a line built for professionals in partnership with sponsored bodybuilder Andrei Deiu. This is fitting, as Infinite is loaded. With ingredients like EndoFlo, NeuroRush, Cognizin, Zynamite, and RipFACTOR, the formula is impressive.

Interestingly, the total caffeine content is 280 milligrams, which is a moderate dose, but it’s backed by a double yohimbe blend. In other words, you’ll definitely be feeling it.

We’ll dive into how ProSupps Infinite Pre Workout works, but first, let’s check PricePlow for good ProSupps deals and watch our video review of the new flavor:

Pro Supps Pro Series Infinite Pre-Workout – Deals and Price Drop Alerts

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ProSupps Infinite Pre Workout Ingredients

Each 2 scoop (15.88g) serving of Infinite Pre contains the following ingredients:

ProSupps Infinite Pre-Workout Ingredients

  • L-Citrulline – 6g

    Citrulline, a conditionally essential amino acid, plays a key role in enhancing nitric oxide (NO) production,[1] which is crucial during intense training or metabolic stress. Citrulline converts efficiently into arginine, boosting NO levels.[2,3] This leads to vasodilation, improving blood flow, oxygen, and nutrient delivery to tissues while removing metabolic byproducts, which enhances athletic performance, endurance, and recovery.[4-6]

    Research shows that citrulline supplementation can increase power,[7] prolong exercise endurance,[8] reduce muscle soreness,[8] boost growth hormone secretion,[9] and promote muscle synthesis.[10,11] It also helps minimize amino acid breakdown during exercise.

    6 grams is quite a nice dose – the lowest clinically-supported dose is 2.4 grams, and we’re well beyond that. Most athletes are happy with 4 grams or more, but the Pro Series demands more.

  • Beta Alanine – 3.2g

    Beta-alanine is a popular endurance-boosting supplement that works by increasing carnosine levels in muscle tissue. Carnosine helps neutralize lactic acid, which builds up during anaerobic activity and leads to muscle fatigue.[12] Since taking carnosine directly is ineffective due to its low bioavailability, beta-alanine supplementation is the best way to boost carnosine stores, improving endurance by delaying fatigue.[12-14] Meta-analyses of studies on beta-alanine show its effectiveness for exercises lasting 30 seconds to 10 minutes.[13,14]

  • L-Tyrosine – 1.5g

    Tyrosine is an effective anti-stress supplement with nootropic benefits, serving as a precursor to catecholamine neurotransmitters like dopamine, adrenaline, and noradrenaline,[15-17] which are vital for focus, motivation, and energy. It also supports thyroid function by boosting the production of thyroid hormones, T3 and T4, helping mitigate the stress from dieting and exercise.[18,19] Notably, research shows that tyrosine can significantly restore cognitive function in sleep-deprived individuals, making it more effective than caffeine in counteracting the negative effects of lack of sleep on mental performance.[20,21]

    • Aura Scientific

    A new novel ingredient developer named Aura Scientific has launched, with four new ingredients that include a feel-good coffeefruit extract named NeuroRush. Get the first peak here today!

  • RipFactor – 325mg

    RipFACTOR is a synergistic blend of two botanicals, Mangifera indica (mango fruit) and Sphaeranthus indicus (Indian globe thistle), developed to enhance muscle performance and hormonal balance. These extracts are recognized for their antioxidant, anti-inflammatory, and adaptogenic properties, which are critical in supporting recovery, strength, and endurance. The ingredient has been found to increase strength,[22] reduce cortisol, and even boost testosterone.[23]

    Studies highlight RipFACTOR’s effectiveness in boosting strength, endurance, and even testosterone levels, while significantly lowering cortisol. For instance, in one trial, subjects experienced a 30% improvement in grip strength and a 17% increase in free testosterone over 56 days, alongside a marked decrease in cortisol—an indicator of RipFACTOR’s stress-mitigating potential.

    This blend may work through pathways that enhance nitric oxide stability, vasodilation, and an anabolic response, thereby creating a conducive environment for muscular growth and recovery — perfect for a pre-workout supplement.

  • Caffeine Anhydrous – 250mg (of 268mg total yield)

    Caffeine is a potent methylxanthine stimulant that crosses the blood-brain barrier, exerting strong effects on the central nervous system. It enhances mood, focus, and energy by blocking adenosine receptors, which prevents the buildup of adenosine that causes fatigue.[24,25]

    Caffeine also boosts cellular metabolism by inhibiting phosphodiesterase, leading to increased levels of cAMP, which promotes energy production.[24,26,27] Additionally, caffeine is a powerful fat burner, capable of increasing fat burning by up to 50%,[28,29] and can enhance physical performance by improving strength, speed, and endurance.[25,28-30]

    • Aura Scientific EndoFlo Sample

    Just one capsule brings some solid stimulant-free bolt-on pump effects

  • EndoFlo – 250mg

    EndoFlo, developed by Aura Scientific, is a proprietary blend of four botanical extracts designed to enhance vasodilation and circulation.

    1. The first ingredient, mango fruit extract (Mangifera indica), is standardized for mangiferin, which acts as a PDE5 inhibitor, increasing cGMP levels for smooth muscle relaxation and improved blood flow.[31-36] Research also supports its cardiovascular benefits and ability to enhance blood flow to the skin,[34,35] making it a versatile and health-boosting compound. Since this is also in RipFACTOR, we’re going to get some extra mangiferin in the Infinite Pre-Workout!
    2. The second ingredient, black ginger (Kaempferia parviflora), contains the bioactive flavonoid 5,7-dimethoxyflavone (DMF), which has cardioprotective and vasodilatory effects through PDE5 inhibition.[36-39] Black ginger is also linked to improvements in muscular endurance,[40,41] strength,[42,43] and flexibility.[44] The DMF in black ginger has shown anabolic properties in preclinical trials, suggesting it may support strength gains.[43,44]
    3. The third ingredient is ginkgo biloba. Known for enhancing memory through improved cerebral blood flow,[45,46] ginkgo biloba also inhibits PDE5 and PDE4,[47] providing broad cardioprotective benefits.
    4. Pine bark extract, rich in proanthocyanidins and antioxidants, is commonly used for its vasodilatory effects and ability to reduce vessel constriction,[48,49] making it a supportive “defensive” component for overall cardiovascular health.

    EndoFlo is also in the lower-stim ProSupps Jekyll, but if you really want to learn more, see our full deep dive, “EndoFlo: Enhancing Vascular Health, Pumps, and Workout Performance“.

    • ProSupps Infinite Pre-Workout

  • Cognizin – 250mg

    Choline is essential for forming the phospholipid bilayer membranes of cells, regulating what enters and exits, and is also a precursor to acetylcholine, a neurotransmitter vital for learning and memory. Increasing acetylcholine levels enhances both cognitive and psychomotor performance. [50-52]

    Cognizin, a patented form of citicoline from Kyowa Hakko, is unique in its ability to support brain health by promoting acetylcholine and three crucial phospholipids: phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine, which are necessary for membrane synthesis.[53] Citicoline is especially important for brain function, as it is a rate-limiting factor in phosphatidylcholine production, making it more effective than other choline supplements.[54,55]

  • NeuroRush – 150mg

    ProSupps isn’t done with the Aura Scientific ingredients just yet!

    The Infinite Pre also includes NeuroRush, a coffee fruit extract offering cognitive and mental performance benefits. NeuroRush is standardized to contain 50% chlorogenic acid and 5-caffeoylquinic acid, which enhance mental energy and reduce fatigue. A 2019 study showed that 100 mg of coffee fruit extract could significantly reduce mental fatigue and maintain alertness after demanding tasks,[56] with higher doses providing even more intense effects. Coffee fruit extract is also praised for its antioxidant and anti-inflammatory properties, contributing to cognitive performance and mood improvement.[57-59]

    Chlorogenic acid, a key component of coffee fruit extracts, is known for its mood-enhancing and cognitive benefits. Research shows that chlorogenic acid helps improve focus and mental energy,[56] making it a great addition to pre-workouts or fat burners, even in low-stimulant formulas. Two additional studies have demonstrated that beverages containing chlorogenic acids provide immediate cognitive and mood enhancements.[57,58]

    Aura Scientific NeuroRush Sample

    Quick Review: It smells great, and 100 milligrams charges things up… but 200 milligrams is actually intense!

    Coffee fruit extracts like NeuroRush are backed by strong safety research, giving them broad appeal, even among cautious supplement users.[59,60]

    NeuroRush is also in ProSupps Jekyll as well as ProSupps Thermo. Notice a trend — the ProSupps resurgence is really leaning into these ingredients… and it’s working!

    We’ll have a lot more information on NeuroRush soon – word is that Aura Scientific is putting some serious money into its research!

  • Zynamite – 75mg

    Zynamite, an extract from the mango tree (Mangifera indica), contains bioactive compounds that can cross the blood-brain barrier and enhance long-term memory formation by upregulating long-term potentiation.[61] It may have synergistic effects with caffeine, improving cognition and potentially replacing caffeine’s nootropic role.[61]

    Studies also suggest that Zynamite, especially when combined with ingredients like luteolin and quercetin, can enhance athletic performance by improving VO2 max, power output, and oxygen uptake,[62-64] while also reducing muscle damage and accelerating recovery.

    • ProSupps Thermo

    ProSupps Thermo is a new fat burning powder that promises energy and appetite control with exciting new ingredients like CapsiBurn and NeuroRush from Aura Scientific!

  • Infinergy – 50mg

    Infinergy (dicaffeine malate) is a blend of caffeine and malic acid, usually in a 75:25 ratio, designed to provide a smoother, longer-lasting energy boost while reducing side effects like jitters or stomach discomfort. The malic acid acts as a buffer, slowing caffeine absorption. In contrast, caffeine anhydrous delivers a faster but shorter-lasting energy spike.

  • AstraGin – 50mg

    AstraGin is included to try to help improve the absorption of the other ingredients in the Infinite Pre formula. This is a proprietary blend of ginseng and astragalus.

  • zumXR – 25mg

    zumXR is an extended release form of caffeine to even out the stimulation curve and keep you going for longer. This isn’t a large dose, but will add another 18 milligrams of caffeine or so.

    The real zingers come next:

  • Alpha-Yohimbine (2.5mg)

    ProSupps Jekyll

    There’s a new ProSupps Jekyll formula for 2024, and this lower-stim pre-workout is absolutely stacked with four of our favorite ingredients, including two newcomers from Aura Scientific, EndoFlo and NeuroRush!

    Rauwolfia, often standardized for the stimulant alkaloid rauwolscine (also known as alpha-yohimbine or “alpha-yo”), is similar to yohimbine and acts as an alpha-2 adrenergic receptor antagonist.[61,62] By blocking these receptors, rauwolscine promotes the release of fatty acids from fat stores,[63,64] enhancing fat burning and weight loss. It has also been shown to suppress appetite[65] and boost energy availability, with some evidence suggesting it may improve focus.[66]

    Although effective, rauwolscine can cause feelings of anxiousness and increased thermogenesis in some individuals, so it’s recommended to start with a low dose to assess tolerance.

  • Yohimbine (2.5mg)

    Most of the same benefits as Alpha-Yohimbine apply for yohimbine, although yohimbine HCl is often less “aggressive” than alpha-yohimbine. Together, these serve up quite a punch — especially given the large doses!

All ProSupps Infinite Pre Workout flavors

Check out our up-to-date list of Infinite Pre flavors below:

    The ProSupps Resurgence Brings Aura Scientific to the Masses

    Aura Scientific Logo - Wide

    Some ingredients – like citrulline, beta alanine, and caffeine – have so much research behind them that it would be silly not to include them by default in a pre-workout. This doesn’t mean, however, that there isn’t room to innovate. Outfits like Aura Scientific have been doing so for years, and the fruit has been obvious in ingredients like EndoFlo and NeuroRush.

    Out there on the frontier of supplement science, the men in lab coats are creating the next generations of performance ingredients, and brands would be wise to follow in the footsteps of early movers like ProSupps.

    Pro Supps Pro Series Infinite Pre-Workout – Deals and Price Drop Alerts

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    Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

    Posts are sponsored in part by the retailers and/or brands listed on this page.

    About the Author: PricePlow Staff

    PricePlow Staff

    PricePlow is a team of supplement industry veterans that include medical students, competitive strength athletes, and scientific researchers who all became involved with dieting and supplements out of personal need.

    The team's collective experiences and research target athletic performance and body composition goals, relying on low-toxicity meat-based diets.

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    References

    1. Morita, Masahiko, et al; “Oral Supplementation with a Combination of L-Citrulline and L-Arginine Rapidly Increases Plasma L-Arginine Concentration and Enhances NO Bioavailability.”; Biochemical and Biophysical Research Communications; U.S. National Library of Medicine; 7 Nov. 2014; https://www.ncbi.nlm.nih.gov/pubmed/25445598
    2. Ochiai, Masayuki, et al; “Short-Term Effects of L-Citrulline Supplementation on Arterial Stiffness in Middle-Aged Men.”; International Journal of Cardiology; U.S. National Library of Medicine; 8 Mar. 2012; https://www.ncbi.nlm.nih.gov/pubmed/21067832
    3. Agarwal, Umang et al; “Supplemental Citrulline Is More Efficient Than Arginine in Increasing Systemic Arginine Availability in Mice.”; The Journal of nutrition; vol. 147,4; 2017; 596-602; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368575/
    4. Orozco-Gutiérrez JJ, Castillo-Martínez L, Orea-Tejeda A, Vázquez-Díaz O, Valdespino-Trejo A, Narváez-David R, Keirns-Davis C, Carrasco-Ortiz O, Navarro-Navarro A, Sánchez-Santillán R. Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction. Cardiol J. 2010;17(6):612-8. PMID: 21154265. https://journals.viamedica.pl/cardiology_journal
    5. Wong A, Alvarez-Alvarado S, Jaime SJ, Kinsey AW, Spicer MT, Madzima TA, Figueroa A. Combined whole-body vibration training and l-citrulline supplementation improves pressure wave reflection in obese postmenopausal women. Appl Physiol Nutr Metab. 2016 Mar;41(3):292-7. doi: 10.1139/apnm-2015-0465; https://cdnsciencepub.com/doi/10.1139/apnm-2015-0465
    6. Alsop P, Hauton D. Oral nitrate and citrulline decrease blood pressure and increase vascular conductance in young adults: a potential therapy for heart failure. Eur J Appl Physiol. 2016 Sep;116(9):1651-61. doi: 10.1007/s00421-016-3418-7; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983290/
    7. Bailey, Stephen J, et al; “l-Citrulline Supplementation Improves O2 Uptake Kinetics and High-Intensity Exercise Performance in Humans.”; Journal of Applied Physiology (Bethesda, Md. : 1985); U.S. National Library of Medicine; 15 Aug. 2015; https://www.ncbi.nlm.nih.gov/pubmed/26023227
    8. Pérez-Guisado, Joaquín, and Philip M Jakeman; “Citrulline Malate Enhances Athletic Anaerobic Performance and Relieves Muscle Soreness.”; Journal of Strength and Conditioning Research; U.S. National Library of Medicine; May 2010; https://www.ncbi.nlm.nih.gov/pubmed/20386132
    9. Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, Pons A. L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol. 2010 Sep;110(2):341-51. doi: 10.1007/s00421-010-1509-4; https://link.springer.com/article/10.1007/s00421-010-1509-4
    10. Jourdan M, Nair KS, Carter RE, Schimke J, Ford GC, Marc J, Aussel C, Cynober L. Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet – A pilot study. Clin Nutr. 2015 Jun;34(3):449-56. doi: 10.1016/j.clnu.2014.04.019; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309748/
    11. Bahri S, Zerrouk N, Aussel C, Moinard C, Crenn P, Curis E, Chaumeil JC, Cynober L, Sfar S. Citrulline: from metabolism to therapeutic use. Nutrition. 2013 Mar;29(3):479-84. doi: 10.1016/j.nut.2012.07.002; https://www.sciencedirect.com/science/article/abs/pii/S0899900712002584
    12. Trexler, E.T., Smith-Ryan, A.E., Stout, J.R. et al.; “International society of sports nutrition position stand: Beta-Alanine.”; J Int Soc Sports Nutr 12, 30 (2015); https://jissn.biomedcentral.com/articles/10.1186/s12970-015-0090-y
    13. Hobson, R. M., et al. “Effects of β-Alanine Supplementation on Exercise Performance: A Meta-Analysis.” Amino Acids, vol. 43, no. 1, 24 Jan. 2012, pp. 25–37, doi:10.1007/s00726-011-1200-z. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374095/
    14. Saunders, Bryan, et al. “β-Alanine Supplementation to Improve Exercise Capacity and Performance: A Systematic Review and Meta-Analysis.” British Journal of Sports Medicine, vol. 51, no. 8, 18 Oct. 2016, pp. 658–669; https://bjsm.bmj.com/content/51/8/658.long
    15. Mishra, Akanksha, et al. “Physiological and Functional Basis of Dopamine Receptors and Their Role in Neurogenesis: Possible Implication for Parkinson’s Disease.” Journal of Experimental Neuroscience, vol. 12, Jan. 2018, p. 117906951877982, 10.1177/1179069518779829. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985548/
    16. Rajeev Dalal, and Dejan Grujic. “Epinephrine.” Nih.gov, StatPearls Publishing, 2 Apr. 2019. https://www.ncbi.nlm.nih.gov/books/NBK482160/
    17. Smith, Matthew D, and Christopher V Maani. “Norepinephrine.” Nih.gov, StatPearls Publishing, 23 July 2019. https://www.ncbi.nlm.nih.gov/books/NBK537259/
    18. Mullur, Rashmi et al. “Thyroid hormone regulation of metabolism.” Physiological reviews vol. 94,2 (2014): 355-82. doi:10.1152/physrev.00030.2013; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044302/
    19. Rousset, Bernard. “Chapter 2 Thyroid Hormone Synthesis And Secretion.” Endotext. U.S. National Library of Medicine, 2 Sept. 2015; https://www.ncbi.nlm.nih.gov/books/NBK285550/
    20. Attipoe, Selasi, et al. “Tyrosine for Mitigating Stress and Enhancing Performance in Healthy Adult Humans, a Rapid Evidence Assessment of the Literature.” Military Medicine, vol. 180, no. 7, July 2015, pp. 754–765, 10.7205/milmed-d-14-00594; https://academic.oup.com/milmed/article/180/7/754/4160625
    21. Pomeroy, Diane E., et al. “A Systematic Review of the Effect of Dietary Supplements on Cognitive Performance in Healthy Young Adults and Military Personnel.” Nutrients, vol. 12, no. 2, 20 Feb. 2020, p. 545, 10.3390/nu12020545; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071459/
    22. Meher Prasanna Rokkam, et al. “A Proprietary Blend of Sphaeranthus Indicus Flower Head and Mangifera Indica Bark Extracts Increases Muscle Strength and Enhances Endurance in Young Male Volunteers: A Randomized, Double-Blinded, Placebo-Controlled Trial.” Food & Nutrition Research, vol. 67, 27 Jan. 2023, doi:10.29219/fnr.v67.8972. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899043/
    23. Salter, Dawna et al. “A botanical extract blend of Mangifera indica and Sphaeranthus indicus combined with resistance exercise training improves muscle strength and endurance over exercise alone in young men: a randomized, blinded, placebo-controlled trial.” Frontiers in nutrition vol. 11 1393917. 3 May. 2024, doi:10.3389/fnut.2024.1393917. https://www.frontiersin.org/articles/10.3389/fnut.2024.1393917/full
    24. Nehlig A, Daval JL, Debry G.; “Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects”; Brain Res Rev. 1992;17(2):139-170. https://pubmed.ncbi.nlm.nih.gov/1356551/
    25. Nehlig A, Daval JL, Debry G.; “Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects”; Brain Res Rev. 1992;17(2):139-170; https://www.sciencedirect.com/science/article/abs/pii/016501739290012B
    26. Goldstein, E.R., Ziegenfuss, T., Kalman, D. et al.; “International society of sports nutrition position stand: caffeine and performance.”; J Int Soc Sports Nutr 7, 5 (2010); https://jissn.biomedcentral.com/articles/10.1186/1550-2783-7-5
    27. Diepvens, K et al; “Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea;” American Journal of Physiology; 2007; https://journals.physiology.org/doi/full/10.1152/ajpregu.00832.2005
    28. Burke LM. Caffeine and sports performance. Appl Physiol Nutr Metab. 2008 Dec;33(6):1319-34. doi: 10.1139/H08-130; https://cdnsciencepub.com/doi/10.1139/H08-130
    29. Norager, C B, et al; “Metabolic Effects of Caffeine Ingestion and Physical Work in 75-Year Old Citizens. A Randomized, Double-Blind, Placebo-Controlled, Cross-over Study.”; Clinical Endocrinology; U.S. National Library of Medicine; Aug. 2006; https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2006.02579.x
    30. Cappelletti, Simone et al. “Caffeine: cognitive and physical performance enhancer or psychoactive drug?.” Current neuropharmacology vol. 13,1 (2015): 71-88. doi:10.2174/1570159X13666141210215655; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462044/
    31. Di Luigi, Luigi et al. “Phosphodiesterase Type 5 Inhibitors, Sport and Doping.” Current sports medicine reports vol. 16,6 (2017): 443-447. doi:10.1249/JSR.0000000000000422 https://journals.lww.com/acsm-csmr/fulltext/2017/11000/phosphodiesterase_type_5_inhibitors,_sport_and.17.aspx
    32. Blagosklonny, Mikhail V. “From rapalogs to anti-aging formula.” Oncotarget vol. 8,22 (2017): 35492-35507. doi:10.18632/oncotarget.18033 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482593/
    33. Gerstgrasser, Alexandra, et al. “In Vitro Activation of ENOS by Mangifera Indica (CarelessTM) and Determination of an Effective Dosage in a Randomized, Double-Blind, Human Pilot Study on Microcirculation.” Planta Medica, vol. 82, no. 04, 19 Nov. 2015, pp. 298–304, doi:10.1055/s-0035-1558219; https://pubmed.ncbi.nlm.nih.gov/26584454/
    34. Buchwald-Werner, Sybille, et al. “Effects of Mangifera Indica (Careless) on Microcirculation and Glucose Metabolism in Healthy Volunteers.” Planta Medica, vol. 83, no. 10, 10 Feb. 2017, pp. 824–829, doi:10.1055/s-0043-103017; https://pubmed.ncbi.nlm.nih.gov/28187466/
    35. López-Ríos, Laura, et al. “Central Nervous System Activities of Extract Mangifera Indica L.” Journal of Ethnopharmacology, vol. 260, Oct. 2020, p. 112996, doi:10.1016/j.jep.2020.112996; https://www.sciencedirect.com/science/article/pii/S0378874119345416
    36. Wattanapitayakul, Suvara K., et al. “Vasorelaxation and Antispasmodic Effects of Kaempferia Parviflora Ethanolic Extract in Isolated Rat Organ Studies.” Fitoterapia, vol. 79, no. 3, Apr. 2008, pp. 214–16. doi:10.1016/j.fitote.2007.11.017; https://www.sciencedirect.com/science/article/abs/pii/S0367326X07002663
    37. Wattanapitayakul, Suvara K., et al. “Kaempferia Parviflora Ethanolic Extract Promoted NOProduction in Human Umbilical Vein Endothelial Cells.” Journal of Ethnopharmacology, vol. 110, no. 3, Apr. 2007, pp. 559–62. doi:10.1016/j.jep.2006.09.037; https://www.sciencedirect.com/science/article/abs/pii/S0378874106005149
    38. Chaturapanich, G., et al. “Effects of Kaempferia Parviflora Extracts on Reproductive Parameters and Spermatic Blood Flow in Male Rats.” Reproduction, vol. 136, no. 4, Oct. 2008, pp. 515–22. doi:10.1530/REP-08-0069; https://rep.bioscientifica.com/view/journals/rep/136/4/515.xml
    39. Tep-areenan, Patcharin, et al. “Mechanisms of Kaempferia Parviflora Extract (KPE)- Induced Vasorelaxation in the Rat Aorta.” Asian Biomedicine, vol. 4, no. 1, Jan. 2010, pp. 103–11. doi:10.2478/abm-2010-0012; https://sciendo.com/article/10.2478/abm-2010-0012
    40. Toda, Kazuya, et al. “Black Ginger Extract Increases Physical Fitness Performance and Muscular Endurance by Improving Inflammation and Energy Metabolism.” Heliyon, vol. 2, no. 5, May 2016, p. e00115. doi:10.1016/j.heliyon.2016.e00115. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946221/
    41. Huang, Jiapeng, et al. “Black Ginger (Kaempferia Parviflora) Extract Enhances Endurance Capacity by Improving Energy Metabolism and Substrate Utilization in Mice.” Nutrients, vol. 14, no. 18, Sept. 2022, p. 3845. PubMed Central, doi:10.3390/nu14183845; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501856/
    42. Lee, Sunkyu, et al. “Standardized Kaempferia Parviflora Wall. Ex Baker (Zingiberaceae) Extract Inhibits Fat Accumulation and Muscle Atrophy in Ob/Ob Mice.” Evidence-Based Complementary and Alternative Medicine : eCAM, vol. 2018, May 2018, p. 8161042. doi:10.1155/2018/8161042; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994587/
    43. Kim, Changhee, and Jae-Kwan Hwang. “The 5,7-Dimethoxyflavone Suppresses Sarcopenia by Regulating Protein Turnover and Mitochondria Biogenesis-Related Pathways.” Nutrients, vol. 12, no. 4, Apr. 2020, p. 1079. doi:10.3390/nu12041079; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230989/
    44. Sripanidkulchai, Bungorn, et al. “Supplementation of Kaempferia Parviflora Extract Enhances Physical Fitness and Modulates Parameters of Heart Rate Variability in Adolescent Student-Athletes: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.” Journal of Dietary Supplements, vol. 19, no. 2, Mar. 2022, pp. 149–67. doi:10.1080/19390211.2020.1852356; https://www.tandfonline.com/doi/abs/10.1080/19390211.2020.1852356
    45. Mehlsen, J., et al. “Effects of a Ginkgo Biloba Extract on Forearm Haemodynamics in Healthy Volunteers.” Clinical Physiology and Functional Imaging, vol. 22, no. 6, Nov. 2002, pp. 375–78. doi:10.1046/j.1475-097x.2002.00445.x; https://pubmed.ncbi.nlm.nih.gov/12464140/
    46. Silva, Henrique, and Filipe Gazalho Martins. “Cardiovascular Activity of Ginkgo Biloba—An Insight from Healthy Subjects.” Biology, vol. 12, no. 1, Dec. 2022, p. 15. doi:10.3390/biology12010015; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855530/
    47. Campos-Toimil, M., et al. “Inhibition of Type 4 Phosphodiesterase by Rolipram and Ginkgo Biloba Extract (EGb 761) Decreases Agonist-Induced Rises in Internal Calcium in Human Endothelial Cells.” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 20, no. 9, Sept. 2000, pp. E34-40. doi:10.1161/01.atv.20.9.e34; https://www.ncbi.nlm.nih.gov/pubmed/10978267
    48. de la Iglesia, Rocío, et al. “Healthy Properties of Proanthocyanidins.” BioFactors, vol. 36, no. 3, 2010, pp. 159–68. doi:10.1002/biof.79; https://iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.79
    49. Rauf, Abdur, et al. “Proanthocyanidins: A Comprehensive Review.” Biomedicine & Pharmacotherapy, vol. 116, Aug. 2019, p. 108999. doi:10.1016/j.biopha.2019.108999; https://www.sciencedirect.com/science/article/pii/S0753332219305359
    50. Purves D, Augustine GJ, Fitzpatrick D, et al.; “Neuroscience;” 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Acetylcholine. https://www.ncbi.nlm.nih.gov/books/NBK11143/
    51. Hasselmo ME; “The role of acetylcholine in learning and memory;”Curr Opin Neurobiol. 2006;16(6):710–715; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659740/
    52. Jones BE; “From waking to sleeping: neuronal and chemical substrates”. Trends Pharmacol. Sci.; 2005; 26 (11): 578–86; https://www.ncbi.nlm.nih.gov/pubmed/16183137
    53. Babb, S M et al. “Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study.” Psychopharmacology vol. 161,3 (2002): 248-54. doi:10.1007/s00213-002-1045-y; https://link.springer.com/article/10.1007/s00213-002-1045-y
    54. Zhou, Miao-Miao et al. “Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.” Lipids in health and disease vol. 15,1 135. 24 Aug. 2016, doi:10.1186/s12944-016-0305-5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997672/
    55. Rao, A M et al. “CDP-choline: neuroprotection in transient forebrain ischemia of gerbils.” Journal of neuroscience research vol. 58,5 (1999): 697-705; https://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-4547(19991201)58:5%3C697::AID-JNR11%3E3.0.CO;2-B
    56. Reed, Rachelle, et al. “Acute Low and Moderate Doses of a Caffeine-Free Polyphenol-Rich Coffeeberry Extract Improve Feelings of Alertness and Fatigue Resulting from the Performance of Fatiguing Cognitive Tasks.” Journal of Cognitive Enhancement, vol. 3, June 2019. doi:10.1007/s41465-018-0118-8 – https://link.springer.com/article/10.1007/s41465-018-0118-8
    57. Cropley, Vanessa, et al. “Does Coffee Enriched with Chlorogenic Acids Improve Mood and Cognition after Acute Administration in Healthy Elderly? A Pilot Study.” Psychopharmacology, vol. 219, no. 3, Feb. 2012, pp. 737–49. doi:10.1007/s00213-011-2395-0; https://pubmed.ncbi.nlm.nih.gov/21773723/
    58. Camfield, David A., et al. “A Randomised Placebo-Controlled Trial to Differentiate the Acute Cognitive and Mood Effects of Chlorogenic Acid from Decaffeinated Coffee.” PLoS ONE, vol. 8, no. 12, Dec. 2013, p. e82897. doi:10.1371/journal.pone.0082897; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857311/
    59. Saitou, Katsuyoshi, et al. “Effect of Chlorogenic Acids on Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrients, vol. 10, no. 10, 10, Oct. 2018, p. 1337. doi:10.3390/nu10101337; https://www.mdpi.com/2072-6643/10/10/1337
    60. Heimbach, J. T., et al. “Safety Studies on Products from Whole Coffee Fruit.” Food and Chemical Toxicology, vol. 48, no. 8, Aug. 2010, pp. 2517–25. doi:10.1016/j.fct.2010.06.025; https://www.sciencedirect.com/science/article/abs/pii/S0278691510003996
    61. La Marca, S., and R.W. Dunn. “The α-2 Antagonists Idazoxan and Rauwolscine but Not Yohimbine or Piperoxan Are Anxiolytic in the Vogel Lick-Shock Conflict Paradigm Following Intravenous Administration.” Life Sciences, vol. 54, no. 10, Jan. 1994, pp. PL179–PL184, doi:10.1016/0024-3205(94)00556-7; https://pubmed.ncbi.nlm.nih.gov/7906377/
    62. Perry BD, U’Prichard DC; European Journal of Pharmacology; “(3H)rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors;”1981; https://www.ncbi.nlm.nih.gov/pubmed/6276200
    63. Mauriege, P., et al. “Heterogeneous Distribution of Beta and Alpha-2 Adrenoceptor Binding Sites in Human Fat Cells from Various Fat Deposits: Functional Consequences.” European Journal of Clinical Investigation, vol. 17, no. 2, Apr. 1987, pp. 156–165, doi:10.1111/j.1365-2362.1987.tb02395.x; https://pubmed.ncbi.nlm.nih.gov/3034620/
    64. Lafontan, M., and M. Berlan. “Fat Cell Adrenergic Receptors and the Control of White and Brown Fat Cell Function.” Journal of Lipid Research, vol. 34, no. 7, 1 July 1993, pp. 1057–1091; https://pubmed.ncbi.nlm.nih.gov/8371057/ (full-text PDF)
    65. Callahan, Michael F., et al. “Yohimbine and Rauwolscine Reduce Food Intake of Genetically Obese (Obob) and Lean Mice.” Pharmacology Biochemistry and Behavior, vol. 20, no. 4, Apr. 1984, pp. 591–599, 10.1016/0091-3057(84)90309-5; https://pubmed.ncbi.nlm.nih.gov/6145164/
    66. Mizuki, Y., et al. “Differential Effects of Noradrenergic Drugs on Anxiety and Arousal in Healthy Volunteers with High and Low Anxiety.” Progress in Neuro-Psychopharmacology & Biological Psychiatry, vol. 20, no. 8, 1 Nov. 1996, pp. 1353–1367, 10.1016/s0278-5846(96)00131-5; https://pubmed.ncbi.nlm.nih.gov/9004342/

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