‘Merica Labz Napalm Red, White, & Boom Thermogenic Pre: Labor Day 2023 Revamp

This article reflects the updated 2023 version released on Labor Day 2023 (September 4th) with an additional flavor in Jalapeño Margarita.

'Merica Labz Napalm 2023

Every so often, ‘Merica Labz releases a special edition version of their flagship Red, White & Boom Pre-Workout. Napalm Red, White, & Boom was the first of this series originally launched in early 2021 with a combination of a thermogenic and pre-workout. It’s specifically formulated to increase fat metabolism while simultaneously improving focus, pumps, performance, and energy – and now it’s been updated to help you attack fat loss even harder.

Updated Formula!

For Labor Day 2023, Napalm Red White & Boom has had a little makeover – ‘Merica Labz removed eria jarensis and Cocoabuterol, while adding theobromine and yohimbine HCl. Here’s what the new formula looks like:

  • Karate-Chop Performance Blend:
    • L-citrulline
    • Beta-alanine
    • Betaine anhydrous
  • Bleeding Eyes Focus Blend:
    • L-tyrosine
    • Caffeine anhydrous (350 milligrams per serving)
    • Alpha-GPC
    • Halostachine
    • Yohimbine HCl
  • Sweat Like a Lady of the Night in Church Thermogenic Blend:
    MitoBurn

    NNB Nutrition has finally brought us a trusted and tested form of L-BAIBA, which we call an “exercise signal” that kickstarts incredible metabolic processes! It’s known as MitoBurn and it helps kick-start the ‘exercise program’!

    • Mitoburn (L-ꞵ-aminoisobutyric acid) (BAIBA) from NNB Nutrition
    • Green coffee extract
    • Theobromine HCl
    • Gamma butyrobetaine ethyl ester HCL (as ProGBB)

This revamped formula will also feature a refreshed label and brand new flavor to Napalm: Jalapeño Margarita. Keep reading to learn more about Napalm Red, White & Boom, and check out this insane teaser from the ‘Merica Labz Instagram page!

Merica Labz Napalm Red White Boom – Deals and Price Drop Alerts

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Note: This article now reflects the label launched on Labor Day 2023, but older versions of the formula may still be at retailers. Check the label at each retailer to find the one you’re looking for — MericaLabz.com will have the latest formula.

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Red, White & Boom Napalm Ingredients

Every tub of Red, White & Boom Napalm comes with 20 servings. For optimal results, ‘Merica Labz recommends taking one scoop 20 to 30 minutes before exercise. However, with 350 milligrams of caffeine per serving, and some additional exotic stimulants, start with half a serving to assess your tolerance.

Here’s what one serving (~21 grams) of Red, White & Boom Napalm contains:

'Merica Labz Napalm 2023 Ingredients

Not only is Napalm Red, White and Boom a powerful pre-workout, but it’s also a strong thermogenic!

Karate-Chop Performance Blend

  • L-Citrulline – 6000mg

    L-citrulline is a non-essential amino acid that increases nitric oxide production indirectly when it’s converted into another amino acid called L-arginine. Nitric oxide is a chemical messenger that causes blood vessel vasodilation (expansion). The increased diameter of blood vessels helps deliver oxygen-rich blood to working muscles more efficiently.[1,2]

    Moreover, the body is better able to move metabolic waste, such as lactic acid, away from working muscles. Not only does this increase performance, but it also enhances your ability to get a pump.[1,2]

    L-citrulline is also involved in the urea cycle, which is responsible for removing ammonia, a highly toxic molecule.[1,2] Therefore, the amino acid may also help with adenosine triphosphate (ATP) production. Studies have shown that supplementing with L-citrulline prior to exercise can:

    • Reduce fatigue
    • Increase performance
    • Decrease post-exercise soreness
    • Lower blood pressure[1,2]

    With a massive dose of 6 grams of L-citrulline per scoop, you’re guaranteed to get all of the benefits the amino acid has to offer.

  • Beta-Alanine – 3200mg

    'Merica Labz Napalm 2023

    Beta-alanine is also a non-essential amino acid, meaning that the body naturally produces it. Along with the essential amino acid L-histidine, beta-alanine is a direct precursor to carnosine, a dipeptide molecule found in skeletal muscle. The amino acid’s ability to increase carnosine levels is also how it boosts muscular endurance.[3] Since carnosine is a hydrogen ion buffer, it reduces the amount of lactic acid in muscles.

    Lactic acid is a metabolic waste produced by energy systems during intense exercise. Excessively high levels of lactic acid can significantly impair the body’s ability to regenerate ATP, resulting in fatigue. Carnosine can help delay the accumulation of lactic acid, leading to improved muscular endurance and performance. Several studies have shown that beta-alanine is an effective ergogenic aid, especially during activities lasting between one and four minutes.[3]

  • Betaine Anhydrous – 2500mg

    Betaine anhydrous, also known as trimethylglycine, is an organic compound that’s classified as both a methyl donor and osmolyte.

    By serving as an osmolyte, betaine draws water into muscle cells, which

    • Promotes hydration
    • Improves muscular pumps
    • Enhances cell’s resilience to external stressors[4,5]
    Betaine Benefits

    The placebo effect started strong with this group. But… the real gains obliterated placebo in due time with betaine!

    By serving as a methyl donor, betaine assists in reducing homocysteine. This is desirable because higher than normal levels of homocysteine can negatively affect several physiological functions, most notably muscle protein synthesis.[4,5]

    Moreover, high homocysteine levels are associated with heart disease. So supplementing with betaine not only improves your performance and body composition but may also improve your cardiovascular health.[6]

    Betaine carries out its effects by donating a methyl group to homocysteine, converting it back into methionine, which is then used to produce creatine. Multiple studies have shown that supplementing with 2.5 grams of betaine enhances:

    • Power output
    • Strength
    • Lean muscle mass
    • Endurance
    • Fat loss[4,5]

    Since Red, White & Boom Napalm is all about amplifying performance and fat loss, 2.5 grams of betaine is a great addition to the formula.

Bleeding Eyes Focus Blend

  • L-Tyrosine – 1000mg

    Tyrosine Derivatives

    It’s easy to see why we like tyrosine so much – its derivatives bring the intensity and focus! Image courtesy Wikimedia

    L-tyrosine is a non-essential amino acid that’s primarily used to synthesize three neurotransmitters:

    • Dopamine – contributes to motivation, memory, mood, and overall sense of well-being
    • Norepinephrine – enhances fatty acid metabolism, blood glucose levels, and respiration
    • Epinephrine – increases cardiac output and blood glucose levels

    A study published in Military Medicine found that low levels of the neurotransmitters listed above lead to a substantial reduction in cognitive and physical performance.[4] They also showed that supplementing with L-tyrosine prior to a stressful situation, such as exercise, can enhance neurotransmitter production and increase cellular firing in the brain.[4]

    Simply put, tyrosine supplementation prevents the drop-off in dopamine, norepinephrine, and epinephrine levels. Thus, enhancing mental focus, energy, and ability to adapt to stress.

  • Caffeine Anhydrous – 350 mg

    Caffeine is one of the most common ingredients in pre-workouts and thermogenic because of how safe and effective it is. Caffeine can increase both physical and mental energy by inhibiting adenosine from binding to its receptor.[5,7] Adenosine is a nucleoside that decreases neural activity, leading to fatigue and difficulty concentrating.

    In terms of fat loss, caffeine inhibits the enzyme that breaks down cyclic adenosine monophosphate (cAMP), called phosphodiesterase.[5,7] cAMP is a critical secondary messenger that assists in metabolizing fatty acids and glucose. So low levels of cAMP are not very conducive to optimizing fat burning. Moreover, caffeine can decrease pain perception, which may help you exercise for longer periods of time.[5,7]

  • Alpha-GPC 50% (L-alpha glycerylphosphorylcholine) – 300 mg

    To promote acetylcholine production, Red, White & Boom Napalm uses 300 milligrams of alpha-GPC, which is short for alpha-glyceryl phosphorylcholine. Alpha-GPC supplies the body with an exogenous source of choline, an essential nutrient that’s used for acetylcholine synthesis. Acetylcholine is a neurotransmitter that’s highly concentrated in neuromuscular gap junctions (where the central nervous system interacts with skeletal muscle). So acetylcholine is crucial for carrying out muscular contractions.

    Alpha-GPC is commonly used in various sports nutrition supplements because of its ability to increase:

    • Focus
    • Mental energy
    • Mind-to-muscle connection
    • Strength
    • Performance[8-10]
  • Halostachine – 100mg

    'Merica Labz Napalm 2023

    Halostachine is a stimulant that works as a beta adrenergic agonist.[11] When halostachine activates your beta-2 adrenoreceptors, this upregulates cyclic adenosine monophosphate (cAMP), a hormone that instructs your cells to burn sugar and fat for energy.[12]

    Halostachine can activate the fight or flight response, which causes your body to rapidly generate energy that can be used to escape or negotiate life-threatening situations. It also leads to bronchodilation, an opening of your airways that can help improve athletic performance.[13]

    That quick jolt of energy can help you push through especially challenging workouts. Just to give you an intuitive point of comparison for halostachine’s effects, it’s about 20% as powerful as adrenaline, which is also a beta adrenergic agonist.[14]

  • Yohimbine HCl – 3 mg

    Yohimbine is an alpha-2 adrenergic antagonist. It feels a lot like halostachine, which we just discussed above, because yohimbine activates adrenaline and noradrenaline receptors in the central nervous system, which enables it to imitate the action of those hormones. Specifically, yohimbine can activate your central nervous system, thus suppressing appetite,[15] speeding up weight loss,[16] and improving focus.[17]

    While yohimbine does have a good safety profile, be warned that many people experience transient anxiety symptoms after taking it.

Sweat Like a Lady of the Night in Church Thermogenic Blend

  • MitoBurn (L-ꞵ-Aminoisobutyric Acid) – 500mg

    MitoBurn PricePlow

    MitoBurn (L-BAIBA) has flipped the fat burner niche on its head by supplying more of this exercise-based signaling molecule to dieters

    ‘Merica Labz is one of the few companies to use 500 milligrams of MitoBurn in a fully loaded pre-workout! A branded ingredient from NNB Nutrition, MitoBurn is a relatively novel compound, but it has some very promising research behind it.

    As of writing this article, it’s the only form of L-ꞵ-aminoisobuytric acid (L-BAIBA) on the market. There are two types of BAIBA: L-BAIBA and D/R-BAIBA. Although they both offer some benefits, research shows that L-BAIBA has the most potential in terms of metabolic enhancement.[18-21]

    Technically, MitoBurn is classified as a myokine, which means that it’s naturally produced by skeletal muscle during exercise and carries out effects through cell signaling. Exercise releases increasing amounts of L-BAIBA, which causes a chain reaction that results in enhanced thermogenesis and fatty acid oxidation.[18-21]

    Although it’s marketed as a weight-loss supplement, MitoBurn’s benefits extend beyond that. It has been shown to:

    • Improve insulin sensitivity
    • Increase glucose tolerance
    • Prevent bone loss
    • Assist white adipose tissue (stored fat) convert to brown (produces heat)[18-21]

    So regardless of your goals (i.e. lose fat or build muscle), MitoBurn can amplify your results.

    NNB Nutrition MitoBurn

    MitoBurn from NNB Nutrition has been tested out to be a pure form of BAIBA on the market!

    Learn more about MitoBurn in our article, titled MitoBurn: β-Aminoisobutyric Acid (L-BAIBA) from NNB Nutrition, and go even deeper on L-BAIBA in another article, BAIBA: New Weight Loss Ingredient Generates Exercise in a Pill?!

  • Green Coffee Bean Extract (Coffea arabica) (50% chlorogenic acids) – 500 mg

    Green coffee bean extract (GCE) is a rich source of chlorogenic acid (CGA), a polyphenol that expresses several beneficial properties, such as:

    • Anti-inflammatory
    • Antidiabetic
    • Anti-obesity
    • Antioxidant
    • Anti-carcinogenic[22]

    'Merica Labz Napalm 2023

    Research shows that CGA helps regulate lipid and glucose metabolism.[22] A systematic review published in the journal Gastroenterology Research and Practice revealed that GCE reduced glucose absorption in the intestine and hepatic triglycerides accumulation. Researchers hypothesized that GCE downregulates fatty acid and cholesterol synthesis while boosting fatty acid oxidation.[22]

    Another study published in the journal Phytotherapy Research found that CGAs help free fatty acids from human adipose tissue with or without the presence of caffeine. Based on this finding, GCE may assist in weight loss by increasing fatty acid oxidation and regulating blood glucose levels.[23]

  • Theobromine HCl – 200 mg

    Theobromine is, like caffeine, a stimulant methylxanthine. It occurs naturally in tea and coffee, in small amounts – chocolate is a much more abundant source of theobromine.[24]

    Like caffeine, theobromine downregulates an enzyme called phosphodiesterase, which is responsible for degrading cyclic adenosine monophosphate (cAMP), one of your body’s “make energy now” hormones.[25] A rise in cAMP means faster cellular metabolism, and ultimately, more calories burned.

    Upregulating cAMP can also activate a protein called peroxisome proliferator-activated receptor-γ coactivator (PGC-1α),[26] which causes fat browning, a process in which metabolically inactive white adipose tissue (WAT) gets converted to metabolically active brown adipose tissue (BAT).

    By this and other mechanisms, theobromine converts WAT to BAT so significantly that it’s considered a thermogenic substance.[27]

    This matters because BAT is part of your body’s mechanism for maintaining its core temperature – BAT burns calories for heat in a process called thermogenesis. This is just more extra calories burned, which can accelerate weight loss assuming caloric intake is held constant.

  • Gamma Butyrobetaine Ethyl Ester HCl (ProGBB) – 25 mg

    ProGBB

    Looking for trusted, lab-tested GBB? Then it’s SYNMR’s ProGBB! Click the image or read more below

    If you’re not a fan of sweating, then steer clear of this ingredient! ProGBB is a trademarked form of gamma butyrobetaine (GBB) ethyl ester HCL. It’s developed by SYNMR Biotechnologies. We like to call ProGBB the “super carnitine that makes you sweat,” since it significantly elevates metabolism.[28]

    Gamma-butyrobetaine is an intermediate that the body uses to create L-carnitine via the gamma-butyrobetaine dioxygenase (BBD) enzyme.[28] Carnitine is essential for fat loss because it’s responsible for transporting fatty acids into the mitochondria to be used for ATP production. Without a sufficient amount of L-carnitine available, fat loss will come to a screeching halt. Studies show that supplementing with GBB is an effective way to increase your body’s L-carnitine stores, which helps facilitate fat loss.[28]

Red, White & Boom Napalm V1 Flavors

Here’s an updated list of all Red, White & Boom Napalm flavors:

    The 2023 Napalm Announcement

    ‘Merica Labz: Never Big Enough

    'Merica Labz F'n Pump'd Non-Stim Pre-workout

    Lookin to add some more pump to Napalm? Check out F’n Pump’d!

    ‘Merica Labz has been on fire lately (pun intended), showcasing their powerhouse formulating with their recent new pre-workout Z-Bomb, and now this revamped Napalm to crank the heat up a notch.

    Since day one, ‘Merica Labz’ motto has been “Never big enough.” It means making effective supplements that are borderline over the top — in a good way. We’ve seen far too many companies cut corners by underdosing ingredients. We’ve never seen that problem with a supplement by ‘Merica Labz.

    So set your alarms for Labor Day 2023 and be on the lookout for the new and improved Napalm Thermogenic Pre-Workout!

    Merica Labz Napalm Red White Boom – Deals and Price Drop Alerts

    Get Price Alerts

    No spam, no scams.

    Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

    Posts are sponsored in part by the retailers and/or brands listed on this page.

    About the Author: Mike Roberto

    Mike Roberto

    Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

    Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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    References

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    2. Bailey, S. et al. Aug. 2015. “L-Citrulline Supplementation Improves O2 Uptake Kinetics and High-Intensity Exercise Performance in Humans.” Journal of Applied Physiology vol. 119,4; 385-95. https://journals.physiology.org/doi/full/10.1152/japplphysiol.00192.2014
    3. Hobson, RM. et al. Jan. 2012. “Effects of β-alanine Supplementation on Exercise Performance: A Meta-Analysis.” Amino Acids vol. 43,1: 25-37. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374095/
    4. Attipoe, S., et al. July 2015. “Tyrosine for Mitigating Stress and Enhancing Performance in Healthy Adult Humans, a Rapid Evidence Assessment of the Literature.” Military Medicine vol. 180, 7. 754-65. https://academic.oup.com/milmed/article/180/7/754/4160625#101253256
    5. Trexler, E. et al. Sept. 2017. “Effects of Coffee and Caffeine Anhydrous on Strength and Sprint Performance.” European Journal of Sports Science vol. 16,6; 702-10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803635/
    6. Ganguly P, Alam SF. Role of homocysteine in the development of cardiovascular disease. Nutr J. 2015 Jan 10;14:6. doi: 10.1186/1475-2891-14-6. PMID: 25577237; PMCID: PMC4326479. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326479/
    7. Grgic, J. et al. Mar. 2018. “Effects of Caffeine Intake on Muscle Strength and Power: A Systematic Review and Meta-Analysis.” Journal of The International Society of Sports Nutrition vol. 15,11. https://jissn.biomedcentral.com/articles/10.1186/s12970-018-0216-0
    8. Bellar, D. et al. Nov. 2015. “The Effect of 6 Days of Alpha Glycerylphosphorylcholine on Isometric Strength.” Journal of the International Society of Sports Nutrition vol. 12, 42. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/
    9. Ziegenfuss T. et al. Sep. 2008. “Acute Supplementation with Alpha-Glycerylphosphorylcholine Augments Growth Hormone Response to, and Peak Force Production During, Resistance Exercise.” Journal of the International Society of Sports Nutrition. 5,1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313098/
    10. Parker, AG. et al. Sep. 2015. “The Effects of Alpha-Glycerylphosphorylcholine, Caffeine or Placebo on Markers of Mood, Cognitive Function, Power, Speed, and Agility.” Journal of the International Society of Sports Nutrition vol. 12,1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595381/
    11. Yao, Xiaojie, et al. “Coupling Ligand Structure to Specific Conformational Switches in the β 2 -Adrenoceptor.” Nature Chemical Biology, vol. 2, no. 8, 1 Aug. 2006, pp. 417–422; https://www.nature.com/articles/nchembio801z (archived at med.stanford.edu)
    12. Xiao RP, Hohl C, Altschuld R, Jones L, Livingston B, Ziman B, Tantini B, Lakatta EG. Beta 2-adrenergic receptor-stimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation. J Biol Chem. 1994 Jul 22;269(29):19151-6; https://pubmed.ncbi.nlm.nih.gov/8034672/
    13. Johnson, M. “Beta2-Adrenoceptors: Mechanisms of Action of Beta2-Agonists.” Paediatric Respiratory Reviews, vol. 2, no. 1, 2001, pp. 57–62; 10.1053/prrv.2000.0102; https://pubmed.ncbi.nlm.nih.gov/16263481/
    14. Liapakis, George, et al. “Synergistic Contributions of the Functional Groups of Epinephrine to Its Affinity and Efficacy at the β2 Adrenergic Receptor.” Molecular Pharmacology, vol. 65, no. 5, 1 May 2004, pp. 1181–1190; 10.1124/mol.65.5.1181; https://molpharm.aspetjournals.org/content/65/5/1181.long
    15. Lafontan, M., et al. “Alpha-2 Adrenoceptors in Lipolysis: Alpha 2 Antagonists and Lipid-Mobilizing Strategies.” The American Journal of Clinical Nutrition, vol. 55, no. 1 Suppl, 1 Jan. 1992, pp. 219S227S, 10.1093/ajcn/55.1.219s; https://pubmed.ncbi.nlm.nih.gov/1345885/
    16. Callahan, Michael F., et al. “Yohimbine and Rauwolscine Reduce Food Intake of Genetically Obese (Obob) and Lean Mice.” Pharmacology Biochemistry and Behavior, vol. 20, no. 4, Apr. 1984, pp. 591–599, 10.1016/0091-3057(84)90309-5; https://pubmed.ncbi.nlm.nih.gov/6145164/
    17. Mizuki, Y., et al. “Differential Effects of Noradrenergic Drugs on Anxiety and Arousal in Healthy Volunteers with High and Low Anxiety.” Progress in Neuro-Psychopharmacology & Biological Psychiatry, vol. 20, no. 8, 1 Nov. 1996, pp. 1353–1367, 10.1016/s0278-5846(96)00131-5; https://pubmed.ncbi.nlm.nih.gov/9004342/
    18. Tanianskii, D. et al. Feb. 2019. “Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid Metabolism.” Nutrients vol. 11,3; 524. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470580/
    19. Kitase, Y. et al. Feb. 2018. “β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor.” Cell Reports vol. 22,6; 1531-44. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832359/
    20. Roberto, M. Nov. 2019. “BAIBA: New Weight Loss Ingredient Generates Exercise in a Pill?!” PricePlow Blog. https://blog.priceplow.com/supplement-research/baiba
    21. Roberto, M. Dec. 2019. “MitoBurn: β-Aminoisobutyric Acid (L-BAIBA) from NNB Nutrition.” PricePlow Blog. https://blog.priceplow.com/supplement-ingredients/mitoburn
    22. Onakpoya, I. et al. 2011. “the Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.”Gastroenterology Research and Practice vol. 2011. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943088/
    23. Flanagan, J. et al. 2014.”Lipolytic Activity of Svetol, a Decaffeinated Green Coffee Bean Extract.” Phytotherapy Research, vol. 28,6; 946-8. https://pubmed.ncbi.nlm.nih.gov/24338784/
    24. “Theobromine – an Overview | ScienceDirect Topics.” ScienceDirect; https://www.sciencedirect.com/topics/neuroscience/theobromine
    25. ‌Sugimoto, Naotoshi, et al. “Chronic Administration of Theobromine Inhibits MTOR Signal in Rats.” Basic & Clinical Pharmacology & Toxicology, vol. 124, no. 5, 12 Dec. 2018, pp. 575–581, 10.1111/bcpt.13175 ; https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.13175
    26. Liang, Huiyun, and Walter F Ward. “PGC-1alpha: A Key Regulator of Energy Metabolism.” Advances in Physiology Education, vol. 30, no. 4, 2006, pp. 145–51; https://journals.physiology.org/doi/full/10.1152/advan.00052.2006
    27. ‌Jang, Myeong & Kang, Nam & Mukherjee, Sulagna & Yun, Jong Won. (2018). Theobromine, a Methylxanthine in Cocoa Bean, Stimulates Thermogenesis by Inducing White Fat Browning and Activating Brown Adipocytes. Biotechnology and Bioprocess Engineering. 23. 10.1007/s12257-018-0434-y; https://www.researchgate.net/publication/329990151_Theobromine_a_Methylxanthine_in_Cocoa_Bean_Stimulates_Thermogenesis_by_Inducing_White_Fat_Browning_and_Activating_Brown_Adipocytes
    28. Roberto, M. Feb. 2019. “ProGBB: The Gamma Butyrobetaine Supplement that Enhances Carnitine.” PricePlow Blog. https://blog.priceplow.com/supplement-ingredients/progbb

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