Unmatched Supps Collagen Peptide-6: Advanced Multi-Source Collagen for Men's Longevity and Performance

When did collagen become a women's-only supplement?!

When did collagen become women's-only supplement?! Unmatched Supps Collagen Peptide-6 provides 6 collagen types from 3 premium sources with PureWay-C and MitoPrime. Joint health and structural support for men who train hard and care about longevity.

Somewhere along the way, the supplement industry decided that structural protein support, joint health, and cellular resilience were feminine concerns. Meanwhile, men crushing heavy training sessions, dealing with joint wear from decades of athletics, and actually caring about their longevity got left out of the conversation.

Unmatched Supps Collagen Peptide-6 flips that script entirely. This isn't some underdosed beauty powder with a token amount of collagen and a mountain of marketing. It's a clinically-dosed longevity formula that provides six types of collagen from three premium sources:

1. Grass-fed bovine peptides,
2. Wild-caught Pure Marine fish collagen, and
3. Eggshell membrane extract.

The formula goes further with PureWay-C to support your body's natural collagen synthesis, MitoPrime ergothioneine to protect the fibroblast cells that actually produce collagen, and targeted digestive enzymes to maximize absorption.

If you're a biohacker, longevity enthusiast, or athlete who refuses to leave gains on the table because of outdated gender stereotypes, this formula deserves your attention. Just as Unmatched Longevity Test addresses hormonal optimization from multiple angles and Longevity Sleep tackles recovery as a complete system, Collagen Peptide-6 brings the same comprehensive, research-backed approach to structural protein support.

Subscribe to PricePlow's Unmatched Supps news alerts and check availability below, then let's break down the formula:

Why Men Need Collagen (Yes, Really)

Let's address the elephant in the room: collagen isn't just about skin appearance. It's the most abundant structural protein in your body, making up roughly 30% of your total protein content. Your tendons, ligaments, cartilage, bones, skin, blood vessels, and even your gut lining depend on collagen for structural integrity.

If you're training hard, you're breaking down collagen. If you're aging (which you are), your natural collagen production declines roughly 1% per year after age 25. If you've spent years or decades in the gym, playing sports, or doing manual labor, you've accumulated microtrauma that your body needs to repair. And if you care about longevity -- not just living longer but maintaining strength, mobility, and resilience as you age -- supporting collagen production isn't optional.

The research on collagen supplementation shows benefits for joint comfort, connective tissue integrity, exercise recovery, and yes, skin health. There's nothing feminine about wanting your joints to work properly or your body to recover efficiently. Too many of these products are marketed towards women. But not this one.

Collagen Peptide-6 delivers these benefits through strategic sourcing and intelligent supporting ingredients that optimize both absorption and your body's endogenous collagen production. Let's get into the formula now.

Unmatched Supps Collagen Peptide-6 Ingredients

Each serving (1 scoop, 15g) provides the following:

• Collagen Peptide-6 - 10.5g

  This is a three ingredient blend developed over 18 months by Kris Gethin, Doug Miller, and their team of experts:

  • Grass-Fed Bovine Collagen (Types I & III) - 9g

    At 9 grams per serving, this grass-fed bovine collagen delivers the two most abundant collagen types in your body. Type I makes up roughly 90% of your body's total collagen and provides the structural framework for skin, bones, tendons, and ligaments. Type III works alongside Type I in more elastic tissues like blood vessels, intestinal walls, and muscles -- important for athletes dealing with tissue repair and remodeling.

    Bovine collagen peptides are enzymatically hydrolyzed into smaller peptide chains (typically 2-10 amino acids) that your body can actually absorb and utilize. Research shows these peptides don't just provide raw amino acid building blocks, though: specific di- and tri-peptides containing hydroxyproline can signal your fibroblasts to increase endogenous collagen production.^[1] It's often about signaling more than mere substrate!

    The amino acid profile matters here: bovine collagen provides high concentrations of glycine, proline, and hydroxyproline, which are amino acids your body specifically needs for collagen synthesis but often under-consumes in modern diets focused on muscle meat. This isn't a complete protein source (it's low in essential amino acids like tryptophan), but that's not the point. You're getting this for targeted structural support, not muscle protein synthesis.

    The 9-gram dose sits well above the threshold where clinical research demonstrates benefits for joint comfort and connective tissue integrity, typically seen at 5-10 grams daily. And we're not done yet...

  • Pure Marine Fish Collagen Peptides (Types I, II, III & IV) - 1g

    

    Marine fish collagen brings something bovine collagen can't: all four structural collagen types in a single source, with superior bioavailability. While the 9-gram bovine dose handles the heavy lifting for joints and connective tissue, this 1-gram marine addition fills strategic gaps.

    Here's why it matters: marine collagen peptides absorb at roughly 60% efficiency versus 40% for bovine sources, and they're transported directly via your intestinal PepT1 receptor rather than requiring full digestion.^[2] Once absorbed, these peptides act as signaling molecules (matrikines) that bind fibroblast receptors and activate the NF-κB p65 pathway, directly upregulating your body's own collagen production.^[2]

    The research shows marine collagen peptides remain bioactive in skin tissue for over two weeks after supplementation, with clinical data demonstrating 9% increases in dermal collagen density and 7-fold improvements in tissue hydration.^[2] Beyond vanity, this is also about maintaining tissue integrity across your entire body as you age and train hard.

  • Eggshell Membrane Powder (Types V & X) - 500mg

    Eggshell membrane brings two more collagen types the other sources can't provide: Types V and X. But it's not just about filling gaps in the collagen profile. This tissue-thin membrane between the eggshell and egg white provides a complete matrix of structural proteins your joints actually need.

    The membrane naturally contains chondroitin sulfate, dermatan sulfate, hyaluronic acid, and keratan sulfate, alongside collagen and elastin. This combination mirrors the organic composition of healthy bone and cartilage tissue.^[3] Think of it as a "pre-assembled scaffold" that supports connective tissue integrity rather than just isolated amino acids.

    Clinical research demonstrates why the 500mg dose matters. An 8-week randomized trial comparing 300mg and 500mg doses found the higher dose produced significantly greater improvements in joint functionality and muscle strength alongside pain reduction.^[4] The mechanism appears to involve reducing pro-inflammatory cytokines like TNF-α and IL-1 while supporting healthy calcium metabolism.^[3]

  

  Combined with the bovine and marine sources, you're getting comprehensive collagen support across six different types rather than just high doses of a single form.

• Vitamin C (as PureWay-C [ascorbic acid & citrus bioflavonoids]) - 90mg

  Vitamin C functions as an essential cofactor for the enzymes that stabilize collagen's triple-helix structure. Without adequate vitamin C, your fibroblasts can't produce functional collagen regardless of amino acid availability. PureWay-C combines ascorbic acid with lipid metabolites (fatty acids) and citrus bioflavonoids, demonstrating 233% higher cellular retention compared to standard ascorbic acid at 30 and 45 minutes post-dose.^[5]

  The lipid metabolites help vitamin C cross cellular membranes more efficiently, while citrus bioflavonoids provide additional antioxidant protection. Research shows this enhanced bioavailability translates to superior cellular uptake in fibroblasts (the cells that produce collagen), with faster absorption across multiple time points compared to other vitamin C forms.^[6] This 90mg dose provides clinically-relevant support for collagen synthesis.

• Hyaluronic Acid (as sodium hyaluronate) - 240mg

  Hyaluronic acid (HA) works alongside collagen to maintain joint health and tissue hydration. This glycosaminoglycan is a major component of synovial fluid, where it lubricates joints and enables nearly frictionless movement.^[7]

  HA isn't absorbed intact after oral ingestion. Gut bacteria break it down into smaller oligosaccharides that are absorbed in the large intestine and distributed to joints, bones, and skin.^[8] Research using radiolabeled HA confirms these fragments reach target tissues.^[7]

  

  Oral hyaluronic acid also triggers anti-inflammatory signaling by binding to Toll-like receptor-4 in intestinal cells, which upregulates interleukin-10.^[7] This mechanism helps explain why clinical trials consistently demonstrate oral HA reduces knee pain and improves joint function. Combined with six collagen types, HA provides both structural support and joint lubrication.

• Biotin (as d-biotin) - 2,500mcg

  The large dose of biotin here provides 8,333% of your daily value, delivering far more than basic nutritional support. This B-vitamin acts as an essential coenzyme for five carboxylases, four of which operate in your mitochondria where energy production happens.^[9]

  These enzymes catalyze critical metabolic reactions: pyruvate carboxylase supports your TCA cycle and gluconeogenesis, propionyl-CoA carboxylase breaks down branched-chain amino acids like leucine and valine (the same amino acids abundant in the collagen peptides you're consuming), and acetyl-CoA carboxylases regulate fatty acid metabolism and cellular energy partitioning.^[9] The high dose ensures these metabolic pathways run efficiently while you're breaking down and rebuilding tissue during training and recovery.

• PepZyme AG (Proteases) - 50mg

  PepZyme AG is a microbial-derived acid protease (digestive enzyme for proteins) from Aspergillus niger standardized to 75,000 HUT/g that helps break down proteins during digestion. What sets this apart from typical plant-based proteases like papain or bromelain is its stability across the harsh pH conditions of the gastrointestinal tract.

  Research shows PepZyme AG improves protein digestion more effectively than plant-based alternatives. In simulated digestion studies, it increased the degree of protein hydrolysis and generated more low-molecular-weight peptides (≤6kDa) during gastric digestion -- the type that absorb faster in the intestine.^[10] The same study found it enhanced antioxidant and antidiabetic properties of digested proteins, benefits not seen with plant enzymes.

  

  Beyond energy metabolism, biotin plays a direct role in keratin formation and structural protein synthesis. Clinical research using this exact 2,500mcg dose demonstrated a 25% increase in nail thickness and reduced splitting after several months of supplementation, with scanning electron microscopy confirming improved cellular structure.^[11] Since nails (like animal hooves) are made of keratin, and biotin supports the production of both keratin and intercellular cement substance, this dose complements the collagen peptides by supporting multiple pathways of structural protein formation throughout your body.

• MitoPrime (L-Ergothioneine) - 10mg

  Here's where Collagen Peptide-6 goes beyond just providing raw materials. MitoPrime (L-ergothioneine) protects the fibroblasts themselves, which are the cells responsible for producing collagen in the first place.^[12]

  Ergothioneine works through multiple protective mechanisms. It scavenges reactive oxygen species that would otherwise damage fibroblast DNA and mitochondria, activates the Nrf2/ARE antioxidant pathway to upregulate cellular defense systems, and directly suppresses MMP-1 (matrix metalloproteinase-1), the enzyme that breaks down collagen.^[12][13]

  Research also shows ergothioneine can prevent UV-induced collagen degradation and maintain type I procollagen production in fibroblasts.^[14] Think of it this way: the collagen peptides provide building blocks, while MitoPrime protects the cellular machinery that assembles them.

  

  Unmatched Supps Longevity Multi+ is a 7-packet daily system that makes your average multivitamin look like child's play. We're talking clinical doses of everything from Spectra antioxidants to spermidine for cellular longevity.

  The 10mg dose sits in the research-validated range for cellular protection benefits. You'll find ergothioneine as a core component of Unmatched Supps Longevity Multi, where we discuss its role in The Cellular Energy Triangle: How Glutathione, Ergothioneine, and PQQ Work Together for comprehensive longevity support.

  Phenomenal addition here, and a great way to finish a novel collagen supplement. Ergothioneine is one of the most underrated ingredients in all of dietary supplements, and Unmatched knows this, using it in multiple formulas now.

Flavors Available

Here's an up-to-date list of all flavors of Unmatched Supps Collagen Peptide-6:

How to Use

• When to take it: Most users take one scoop daily, mixed with 8-12oz of water or your beverage of choice. You can take it any time of day, though many prefer post-workout or before bed to support recovery.
• Coffee creamer hack: Kris Gethin uses the unflavored version in his coffee daily as a creamer substitute. At 51, he credits consistent collagen supplementation for maintaining healthy skin and supporting joint recovery -- especially after knocking out a chunk of cartilage in his shoulder while snowboarding.
• Flexible dosing: The unflavored version mixes easily into protein shakes, smoothies, oatmeal, or cream of rice without altering taste. Flavored versions work well as standalone beverages.
• Consistency matters: Collagen supplementation works best with daily, consistent use over weeks and months rather than sporadic dosing.

Unmatched Supps Longevity Sleep features 250mg PeptiSleep™ (AI-discovered peptide from Nuritas), 3g glycine, 3g GABA, tart cherry, Senactiv, and ZMA. Multi-pathway approach helps you fall asleep faster, stay asleep longer, and wake up recovered.

Stacks Well With

• Unmatched Longevity Sleep: Collagen synthesis happens primarily during deep sleep. Pairing these two formulas creates a powerful recovery stack that addresses both the raw materials (collagen peptides) and the environment where your body rebuilds tissue (quality sleep).
• Unmatched Longevity Test: Healthy testosterone levels support muscle protein synthesis and connective tissue repair. Combined with Collagen Peptide-6's structural support, you're addressing both the hormonal environment and the building blocks for tissue maintenance.
• Unmatched Longevity Multi: The comprehensive vitamin, mineral, and cellular longevity support in Longevity Multi pairs perfectly with Collagen Peptide-6's structural focus. Together, they cover both foundational nutrition and targeted tissue support.

Who It's For

• Athletes and lifters: If you're putting serious stress on joints, tendons, and connective tissue through training, collagen provides the raw materials your body needs for repair and maintenance.
• Longevity-focused men: Maintaining structural integrity, mobility, and tissue health as you age isn't optional if you want to keep training and living actively for decades to come.
• Biohackers: If you're already optimizing sleep, hormones, and nutrition, collagen supplementation is a logical next step for comprehensive health span optimization.

Conclusion: Structural Support Without the Pinkified Marketing

Unmatched Supps Longevity Test targets testosterone optimization through 8 clinically-dosed ingredients. KSM-66 Ashwagandha, Furosap, Tongkat Ali, and apigenin work together to support natural test production while managing cortisol and estrogen.

Unmatched Supps Collagen Peptide-6 does something the supplement industry desperately needed: it treats collagen supplementation as a serious longevity and performance tool rather than a beauty product with a pink label. This isn't your typical underdosed collagen powder with token ingredients and impressive marketing.

The formula delivers six collagen types from premium sources (grass-fed bovine, wild-caught marine, eggshell membrane), then enhances the formula with intelligent supporting ingredients like PureWay-C for collagen synthesis, MitoPrime for cellular protection, and digestive enzymes for absorption. Brilliant.

This approach mirrors everything we've seen from Unmatched: comprehensive formulas that address complex biological systems rather than single-ingredient solutions that ignore context. Whether you're stacking it with Longevity Sleep for recovery optimization, Longevity Test for hormonal support, or using it standalone for joint and connective tissue health, Collagen Peptide-6 delivers the clinical dosages and premium sourcing you'd expect from Kris Gethin's longevity-focused brand.

The supplement industry spent years convincing men that collagen was someone else's concern. Unmatched just proved them wrong. Subscribe to PricePlow's Unmatched Supps news alerts below for more launches from this innovative brand, and check pricing and availability: