Podium Nutrition FUSE 2025: Performance Pre-Workout Takes a New Twist

Every year, we see supplement brands come and go… but we don’t always see single brands commit to annual innovation with their own products. Yet that’s exactly what Podium Nutrition is doing with the launch of their new FUSE 2025 Pre-Workout, which we’re proud to announce today.

Podium Nutrition FUSE 2025 Pre-Workout offers 20% more active ingredients at a lower cost. This NSF Certified for Sport formula includes Cognizin citicoline and KSM-66 for enhanced focus while maintaining 200mg caffeine for clean energy.

This isn’t just another formula update; it’s the start of a yearly innovation cycle aimed at keeping athletes ahead of the curve with cutting-edge formulations backed by the latest nutritional science.

FUSE 2025: Podium Nutrition Makes Changes, and Isn’t Afraid to Make More

FUSE 2025 represents a significant evolution from its predecessor (the FUSE Legacy pre-workout), enhancing cognitive function while maintaining the performance-driving ingredients that serious athletes demand. With the “2025” designation, Podium isn’t just dating this formula — they’re making a statement that each year will bring thoughtful updates reflecting the latest advancements in sports nutrition research.

NSF Certified for Sport: Ingredients You Can Trust

While Podium has built a strong reputation within the functional fitness community, FUSE 2025 signals the brand’s expanded focus on supporting athletes across all training modalities. This broader vision doesn’t mean compromising on quality, though: FUSE 2025 is still NSF Certified for Sport, giving athletes at all levels complete confidence that what’s on the label is exactly what’s in the bottle, without banned substances or contaminants.

Same 200mg Caffeine, Now with 250mg Cognizin Citicoline

With 20% more active ingredients than the legacy formula at a lower cost per serving, FUSE 2025 delivers exceptional value alongside enhanced performance benefits. The upgraded cognitive support stack featuring Cognizin® citicoline and KSM-66® ashwagandha extract perfectly complements the physical performance drivers like citrulline, beta-alanine, and betaine anhydrous.

Backed by numerous high-profile sponsored athletes (with exciting new additions on the horizon), Podium continues to demonstrate their commitment to supporting those who demand the best from their bodies… and their supplements. FUSE 2025 launches April 15th, marking the beginning of what promises to be an exciting new chapter for this forward-thinking brand.

Want to experience the next evolution in pre-workout performance? Sign up for PricePlow’s Podium Nutrition alerts and check our deals below, then let’s dig into the label:

Podium FUSE 2025 Ingredients

In a single 17.3-gram scoop (25 servings per container), you get the following:

Podium Performance

• L-Citrulline – 4,000 mg

  Podium FUSE 2025 delivers a classic 4-gram dose of L-citrulline, positioning it as a cornerstone of the formula’s performance-enhancing, pump-inducing effects. This non-essential amino acid is one of the most reliable nitric oxide (NO) boosting ingredients in sports nutrition.

  How L-Citrulline Works

  L-citrulline functions as a precursor to L-arginine in the body, which ultimately leads to increased nitric oxide production.^[1]

  What makes citrulline better than L-arginine itself is its superior bioavailability. When you take L-arginine directly, much of it gets broken down by the enzyme arginase before reaching your bloodstream. L-citrulline, however, bypasses this first-pass metabolism and more effectively raises plasma arginine levels, leading to better sustained NO production.^[2]

  The Benefits for Athletes

  The 4-gram dose in FUSE 2025 is right in the clinical sweet spot where we start seeing meaningful benefits:

  • Enhanced Blood Flow: L-citrulline promotes vasodilation, improving oxygen and nutrient delivery to working muscles.^[3]
  • Reduced Fatigue: By supporting the clearance of ammonia through the urea cycle, citrulline helps buffer exercise-induced fatigue.^[4]
  • Improved Endurance: Research shows citrulline can enhance time to exhaustion and overall work capacity during intense exercise.^[5]
  • Better Recovery: The increased blood flow may help with the removal of metabolic waste products, potentially supporting faster recovery between training sessions.^[6]

  At 4 grams, FUSE 2025 provides an effective clinical dose that sits right in the range shown to deliver measurable performance benefits without reaching the point of diminishing returns (or excessive pumps that make athleticism difficult) seen at higher doses. This makes it an efficient addition to the formula, working synergistically with the other ingredients to maximize your training potential.



• Beta-Alanine – 3,200 mg

  Podium Nutrition didn’t cut corners when it came to beta-alanine in FUSE 2025, providing the clinically-effective (and now standard) dose of 3,200 mg.

  What is Beta-Alanine?

  Beta-alanine is a non-essential amino acid that, when supplemented, combines with histidine in your body to form carnosine, a dipeptide that acts as an important pH buffer in skeletal muscle.^[7]

  This buffering capability is why beta-alanine has become a staple ingredient in high-quality pre-workout formulas like this one. When you’re training hard, especially in the 1-4 minute high-intensity range, your muscles produce hydrogen ions that increase acidity and contribute to fatigue. Carnosine helps buffer these ions, potentially delaying fatigue and enhancing performance.^[8]

  Performance Benefits

  The research on beta-alanine is impressive, showing particular benefits for:

  • High-Intensity Exercise Performance

    Multiple studies demonstrate that beta-alanine supplementation can improve performance in high-intensity exercise lasting between 1-4 minutes, which aligns perfectly with many CrossFit workouts and HIIT training sessions.^[9] Another meta analysis found that beta-alanine supports endurance in exercises lasting from 30 seconds to 10 minutes!^[10] This is especially relevant for Podium’s target audience of functional fitness athletes.

  • Exercise Capacity

    Beta-alanine shows the most pronounced effects on exercise capacity tests rather than fixed-endpoint performance tests, meaning it may help you push harder when you’re going all-out to failure.^[10]

  • Delayed Neuromuscular Fatigue

    Research shows beta-alanine can attenuate neuromuscular fatigue, helping you maintain power output longer during intense training.^[11]

  

  Optimal Dosing

  FUSE 2025’s 3,200 mg dose hits the sweet spot for daily supplementation. Research indicates that 3.2-6.4 g of beta-alanine daily for at least 2-4 weeks increases muscle carnosine levels by 40-60%, with continued increases up to 12 weeks.^[12]

  So while you’ll feel the characteristic tingling sensation (paresthesia) immediately, the performance benefits accumulate over time with consistent use, making FUSE 2025 an ideal daily training partner.

• Betaine Anhydrous – 2,500 mg

  Betaine (trimethylglycine) is a powerful osmolyte and methyl donor that the sports nutrition world continues to frequently use, and Podium has included a clinical 2.5 gram dose in FUSE 2025.

  Originally discovered in sugar beets (hence the name), betaine is found naturally in foods like spinach, wheat, and shellfish, though supplementation provides more consistent dosing.^[13]

  This powerhouse ingredient supports performance through multiple mechanisms. As an osmolyte, betaine helps maintain optimal cellular hydration during intense exercise, protecting proteins and enzymes from stress-induced damage.^[14,15]

  The research on betaine’s benefits is impressive. Studies show that 2.5g daily (exactly what’s in FUSE 2025) can significantly improve power output during sprint cycling, enhance muscle endurance during resistance training, and boost both upper and lower body force production.^[16]

  What sets betaine apart is its ability to work synergistically with other ingredients in the formula. When combined with citrulline and beta-alanine, betaine helps create a comprehensive performance package that addresses multiple aspects of training intensity.

  

  Beyond acute performance, betaine supplementation has been linked to favorable body composition changes. A six-week study found betaine supplementation increased lean mass while reducing fat mass in resistance-trained men.^[14,15] There’s additional research specifically with women showing improved body composition as well.^[17]

  More recent research suggests betaine may enhance the body’s natural testosterone response post-workout and improve recovery markers, making it valuable for supporting long-term training adaptations.^[18]

  The 2.5g dose in FUSE 2025 is spot-on with the research, ensuring you get enough to experience betaine’s full range of benefits for power, endurance, and recovery support, without unnecessary fillers or underdosed ingredients. This demonstrates Podium’s commitment to science-backed formulation for serious athletes.

• Taurine – 1,000 mg

  Taurine is one of the most abundant amino acids in the body, found in high concentrations in muscle tissue, the brain, and heart where it performs numerous essential functions.^[19]

  While often overshadowed by more hyped ingredients, taurine delivers impressive performance benefits that make it a perfect addition to FUSE 2025’s performance matrix. This conditionally essential amino acid is a powerful cell volumizer that helps maintain proper hydration and electrolyte balance during intense training.^[20]

  Performance Enhancement

  Research shows taurine significantly improves endurance performance by enhancing fatigue resistance. A comprehensive meta-analysis found that oral taurine supplementation improves endurance performance with a notable effect size of 0.4, making it as effective as caffeine for extending exercise capacity.^[21]

  

  When it came to reaction time and mental accuracy, CAF*TAU absolutely crushed CAF, TAU, and the placebo.^[22]

  The 1,000 mg dose in FUSE 2025 is right in the research-backed sweet spot, with studies showing doses between 1-6g effectively improve performance outcomes. Interestingly, single acute doses (like what you’ll get pre-workout) are just as effective as chronic loading protocols.^[21]

  Cognitive Enhancement

  Beyond its physical performance benefits, taurine also supports brain function and cognitive performance. It acts as a neuromodulator that can enhance focus during workouts while simultaneously providing neuroprotective effects against exercise-induced stress.^[20]

  Combined with the citicoline, tyrosine, and other cognitive enhancers in FUSE 2025, taurine helps create a comprehensive mental performance stack that keeps you locked in throughout your workout.

Podium Focused Energy

Pumps and endurance are great, but this is where the actual “fuse” is:

• L-Tyrosine – 2,000 mg

  Podium FUSE 2025 contains a hefty 2,000 mg dose of L-Tyrosine, a powerful amino acid that serves as a building block for dopamine and norepinephrine – critical neurotransmitters that regulate focus, mood, and mental performance during intense training sessions.^[23]

  What makes L-Tyrosine especially valuable in a pre-workout formula is its ability to maintain cognitive performance when you’re pushing through stressful situations – like that final grueling set or when you’re training in a sleep-deprived state.^[24]

  

  Unlike many cognitive ingredients, L-Tyrosine doesn’t just work theoretically – it’s been used successfully during physical stress and exhaustion. Research shows it can help preserve mental performance during cold exposure, sleep deprivation, and other challenging conditions that would typically degrade focus and mental clarity.^[25]

  The 2,000 mg dose in FUSE 2025 represents a significant upgrade from many competing pre-workouts, which often include smaller, less effective amounts. This clinical dose ensures you’re getting enough L-Tyrosine to support heightened focus throughout your entire training session – preventing the mid-workout mental fatigue that can sabotage performance.^[26]

  L-Tyrosine works synergistically with caffeine and Cognizin in this formula, creating a comprehensive cognitive enhancement stack that delivers both immediate mental energy and sustained focus without the crash associated with stimulants alone.

• Cognizin® (Citicoline) – 250 mg

  Podium’s FUSE 2025 formula includes Cognizin®, a patented and trademarked form of citicoline made by Kyowa Hakko. This premium nootropic ingredient represents a significant upgrade in the pre-workout’s cognitive support stack.

  Citicoline is more than just an ordinary choline source – it’s the chemical combination of choline and cytidine (a nucleotide molecule). Scientifically known as cytidine diphosphate-choline (CDP-choline), citicoline serves as both a choline donor and contributes to the biosynthesis of phospholipids for neuronal membranes.^[27]

  

  Cognizin® Citicoline is dubbed the The Brain Choline not just because it provides choline, but because it also supplies cytidine, which is also needed for the synthesis of phosphatidylcholine

  What makes Cognizin awesome here is that at this 250mg dose here in FUSE 2025, research shows it helps improve focus and attention and helps support concentration. For athletes, this means sharper mental performance during training sessions when you need it most.^[28]

  Cognizin works by supporting acetylcholine levels, a neurotransmitter crucial for cognitive function, while also supporting brain energy utilization.^[29]

  In a randomized, double-blind, placebo-controlled study, participants who received 250mg of Cognizin daily for 28 days showed significantly better attention performance compared to placebo, making fewer omission and commission errors on attention tests.^[30]

  Athletes will appreciate the dual benefits Cognizin offers – not only does it help maintain focus during intense training sessions, but it also supports overall brain health and phospholipid metabolism, providing both immediate cognitive enhancement and long-term brain support.^[31]

  With 250mg of Cognizin, FUSE 2025 provides the clinically-effective dose shown to support mental performance – a perfect complement to the physical performance drivers in this comprehensive pre-workout formula.

• KSM-66 Ashwagandha Extract – 200 mg

  Podium Nutrition took a twist and included the popular KSM-66 ashwagandha extract in FUSE 2025. KSM-66 is a full-spectrum root extract standardized to contain at least 5% withanolides, bioactive compounds responsible for many of this ancient herb’s impressive benefits.^[32]

  For athletes, KSM-66 delivers a trifecta of performance-enhancing benefits. First, it acts as an adaptogen that helps the body manage stress and maintain hormonal balance during intense training.^[33] This stress-buffering effect is crucial since elevated cortisol levels can sabotage training progress and recovery.

  

  Second, research shows KSM-66 supplementation can significantly increase muscle strength and recovery rates. A landmark 8-week study found that subjects taking ashwagandha experienced substantial improvements in bench press and leg extension strength compared to placebo, with gains up to 138% greater than the control group.^[32]

  Third, KSM-66 has been shown to boost cardiorespiratory endurance, with studies demonstrating improved VO₂ max in subjects taking ashwagandha versus placebo.^[34]

  This section is just focusing on the athletic benefits we’ve seen with ashwagandha (there’s even a meta-analysis supporting the findings).^[35] Beyond these benefits, however, there’s a treasure trove of research supporting reduced cortisol, stress, anxiety, sleep, and so much more when taking larger doses of the herb.^[36,37]

  By including ashwagandha in FUSE 2025, Podium offers athletes a clinically backed ingredient that works synergistically with caffeine and L-tyrosine to enhance mental focus while simultaneously supporting physical performance and recovery. This makes KSM-66 a smart addition to a comprehensive pre-workout formula, addressing both psychological and physiological aspects of training performance.

• Caffeine Anhydrous – 200 mg

  Podium has perfectly dosed the caffeine in FUSE 2025, maintaining the ideal 200mg sweet spot that provides powerful performance benefits without excessive stimulation. This moderate dose hits the balance that most athletes need: enough to significantly boost performance but not so much that it leads to jitters or sleep disturbances.

  Research consistently shows that caffeine at doses of 3-6 mg/kg body weight (about 200-400mg for most athletes) significantly enhances various aspects of exercise performance.^[38] For a 150-pound athlete, 200mg puts you right in that optimal range at about 3mg/kg.

  

  What makes caffeine such a powerful pre-workout ingredient? It works through multiple mechanisms, with the primary one being adenosine receptor antagonism in the central nervous system.^[39] This reduces perceived exertion during training, making your workout feel less challenging while actually performing better.^[40]

  For strength athletes, caffeine has been shown to improve maximal muscle strength, with a systematic review finding significant effects on upper body strength.^[41] Endurance athletes also benefit substantially, with caffeine consistently improving performance by 2-4% across numerous studies.^[42]

  The 200mg dose in FUSE 2025 pairs perfectly with the theobromine (100mg) to create a smoother, more sustained energy curve compared to caffeine alone. This thoughtful combination delivers clean energy without the crash that often accompanies higher-dose caffeine products.

• Theobromine – 100 mg

  Theobromine, a primary methylxanthine in cocoa beans, provides many benefits that go beyond traditional stimulation. Unlike its cousin caffeine, theobromine delivers a smoother, longer-lasting energy profile without the jitters or crash often associated with stimulants.^[43]

  Where theobromine truly shines is in its cardiovascular benefits. Research shows that it can effectively decrease blood pressure while increasing heart rate, making it an ideal component for exercise performance.^[44] Additionally, theobromine demonstrates impressive effects on lipid metabolism, increasing HDL cholesterol while reducing LDL cholesterol.^[45]

  Recent studies have also revealed theobromine’s role in thermogenesis by inducing white fat “browning” and activating brown adipocytes, potentially offering metabolic benefits for those seeking to optimize body composition.^[46]

  

  FUSE 2025’s precise theobromine dose works synergistically with its other ingredients to deliver sustained energy, improved focus, and enhanced metabolic support without overstimulation.

Added Vitamins

• Vitamin C (as Ascorbic Acid) – 90mg (100% DV)

  Vitamin C is a powerhouse antioxidant that provides critical support during intense training sessions. At 90mg (100% DV), FUSE 2025 delivers the perfect daily amount to support immune function when your body is under physical stress. Research shows vitamin C plays a crucial role in collagen synthesis for healthy joints and connective tissue, while also acting as a potent free radical scavenger to combat exercise-induced oxidative stress.^[47]

  Additionally, vitamin C enhances the absorption of non-heme iron, potentially improving oxygen delivery to working muscles. For athletes, this vitamin may help reduce exercise-induced cortisol levels and support faster recovery between training sessions.^[48] Vitamin C also works synergistically with many ingredients in FUSE 2025, making it a smart addition to this comprehensive pre-workout formula.

• Vitamin B6 (as Pyridoxine HCl) – 0.4mg (25% DV)

  Vitamin B6 serves as a crucial cofactor in over 100 enzyme reactions involved in protein metabolism and energy production — exactly what you need during intense training. This essential vitamin helps convert stored glycogen to glucose for immediate energy and assists in the formation of hemoglobin, improving oxygen transport to working muscles.

  B6 also plays a supporting role in neurotransmitter synthesis, working alongside the cognitive enhancers in FUSE 2025 to maintain mental clarity and focus during your most challenging workouts. For athletes looking to maximize both physical output and recovery, this strategic addition to the vitamin matrix provides foundational nutritional support, but certainly not too much of it.

• Folic Acid – 385mcg DFE (100% DV)

  

  Folic acid (vitamin B9) may not get the spotlight like stimulants or pump ingredients, but its presence in FUSE 2025 at 385mcg DFE (100% DV) delivers serious benefits for hard-training athletes. This essential B vitamin plays a critical role in DNA synthesis and repair, especially important during periods of intense training when cellular turnover increases.

  Folic acid works synergistically with vitamin B12 to support red blood cell formation and hemoglobin production, enhancing oxygen transport to working muscles during high-intensity exercise. Additionally, it contributes to proper homocysteine metabolism, supporting cardiovascular health under physical stress. By including the full daily value of this metabolic cornerstone, Podium ensures athletes get comprehensive nutritional support beyond just immediate performance enhancement, addressing both acute training needs and long-term recovery processes in this thoughtfully formulated pre-workout.

• Vitamin B12 – 35mcg (1460% DV)

  At a substantial 35mcg (1460% DV), the vitamin B12 content in FUSE 2025 provides far more than just baseline nutrition — it’s strategically dosed to support energy metabolism during peak performance. B12 is essential for converting carbohydrates into glucose, providing the rapid energy needed during high-intensity training.

  As mentioned above, this crucial vitamin also plays a vital role in red blood cell formation, nerve function, and DNA synthesis, all of which impact athletic performance and recovery. The generous dose addresses the increased metabolic demands of serious training while working synergistically with caffeine and other energizing ingredients to optimize both aerobic and anaerobic energy systems.

Flavors Available

Here’s the current list of Podium FUSE 2025 flavors, with Podium stating on social media that “Your favorite flavors are getting an upgrade”:

How to Stack FUSE 2025

FUSE 2025 is designed to be a comprehensive pre-workout on its own, but for those looking to maximize specific aspects of their training, strategic stacking can take your performance to the next level.

For the ultimate pump experience, pair FUSE 2025 with Podium PUMP. While FUSE delivers the energy, focus, and endurance components with ingredients like caffeine, L-tyrosine, and beta-alanine, Podium PUMP can amplify the nitric oxide production from FUSE’s citrulline. This combination is ideal for training sessions where you want both intense focus and maximum vasodilation.

The stim-free nature of Podium PUMP makes it the perfect complement to FUSE 2025, allowing you to enhance blood flow without increasing the stimulant load. For those intense training days when you need every advantage, this stack delivers comprehensive coverage of all pre-workout bases: energy, focus, endurance, and blood flow.

For those focused on long-term performance and recovery, consider adding Podium Creatine Monohydrate to your daily regimen. While not necessarily taken simultaneously with FUSE 2025, daily creatine supplementation pairs perfectly with the acute benefits of your pre-workout, supporting strength, power output, and cellular hydration over time.

Conclusion: Podium’s Yearly Innovation Promise Begins with FUSE 2025

Podium Nutrition PUMP is a non-stim pre-workout for hybrid athletes, powered primarily by a combination of Nitrosigine and L-citrulline

With FUSE 2025, Podium Nutrition makes a bold statement about their commitment to evolving with the science of sports nutrition. The “2025” in the name isn’t just a year marker — it’s a promise that each year will bring updated formulations incorporating the latest research and ingredient technologies.

This approach shows Podium’s dedication to supporting athletes across the spectrum of functional fitness, from CrossFit boxes to traditional strength training environments and beyond. By focusing on both cognitive and physical performance enhancements, FUSE 2025 acknowledges that elite performance requires both mental sharpness and physical capability.

The formula upgrades, especially the inclusion of Cognizin, KSM-66 and increased L-tyrosine, deliver a more complete pre-workout experience at a better value. With 20% more active ingredients than the legacy formula and a lower cost per serving, FUSE 2025 sets a new standard for what athletes should expect from their pre-workout supplements.

As Podium expands its focus beyond any single fitness methodology to embrace the broader world of functional training and sports performance, FUSE 2025 represents the first step in what promises to be an exciting innovation journey. For athletes serious about their training, this commitment to yearly improvement means your supplement stack will continue evolving alongside your own progress.

Ready to experience the next evolution in pre-workout performance? Grab FUSE 2025 below using PricePlow, and sign up for our Podium news, since there’s a lot more on the way: