APS Mesomorph – Bringing DMAA Back to Pre Workouts!

APS Mesomorph

APS Mesomorph is a high-energy, focus heavy pre workout that brings DMAA back to the masses! Hang on for the ride!

Next to protein powders and fat burners, pre workout supplements are the most popular products in the sports nutrition game. And for a while, they were dominated by the focus-enhancing CNS stimulant ingredient, DMAA, or 1,3 dimethylamylamine.

However, for a long time, DMAA was taboo in pre workouts due to ongoing litigation between the U.S. Government and the supplement companies themselves.

Well, DMAA has made its glorious return to the land of pre workouts with several offerings. After discussing Hi-Tech’s Jack’d Up earlier last year, the next to cover is APS Mesomorph.

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Mesomorph Ingredients

Mesomorph uses 3 different proprietary blends to get you amped up for your impending lift session. Let’s see what it’s got in store, but first, note that this is a max one-scoop serving, and we actually like to keep it at ½ to ¾ scoop, as well explain below:

  • Synthenox-Carnosine / Nitric Oxide Complex (6.5g)

  • Mesoswell-Cell Volumizing ATP Matrix (4.5mg)

    • Di-Creatine Malate

      Creatine Solubility

      Many think creatine nitrate is better than monohydrate due to its higher solubility, but there are no studies validating its effectiveness over mono.

      Creatine Malate is a novel form of creatine that binds the compound to malic acid, similar to citrulline malate. This is done to help improve the bioavailability of creatine ensuring it is readily absorbed by the muscles and not broken down in the stomach to the useless byproduct, creatinine.

      Creatine malate claims to confer all the strength and power benefits of creatine supplementation[11,12] with none of the “bloat” that’s sometimes seen with monohydrate use. Malic acid also helps improve endurance by acting as a buffer in your muscles, similar to what occurs with citrulline malate.[13]

    • Taurine

      Taurine is an incredibly abundant amino acid in the body that’s mainly stored in the muscles, heart, and brain. Typically, there are usually ample amounts of taurine in the body, but during periods of intense exercise, the body can’t produce enough to meet demand, thus making it “conditionally essential.”

      Taurine helps pull water and nutrients, thereby acting as a cell volumizer.[14] Overall, you’ll experience better pumps and reduced delayed onset muscle soreness when supplementing with it.[15]

    • Creatine Nitrate

      Here we have another creatine hybrid that further improves pumps due to its nitrate component. A lot of the bros in the community believe creatine nitrate to be superior monohydrate due to its increased water solubility, which theoretically yields better absorption.

      If you’re here, you’re probably here for the extreme energy and focus, and you sure are going to get it with Mesomorph. Game over.

      However, no current studies on creatine nitrate exist showing it superior to monohydrate in terms of strength, body composition, or athletic performance.

      With that said, the nitrate portion of this molecule will definitely lead to increased pumps – especially since we know it’s at least 300mg worth, a great start for a nitrate compound. Creatine Nitrate is roughly 67.5% creatine, 32.5% nitrate.

      Nitrate synergy with arginine

      To top it off, the nitrate will definitely work very well alongside the arginine up above, making the nitric oxide boost last longer too.[35,36]

    • Ascorbic Acid (300mg Vitamin C)

      More commonly known as Vitamin C, ascorbic acid is a water-soluble vitamin and powerful antioxidant in the body. While early research showed that high doses of antioxidant decreased athletic performance,[16,17] there is so other research that paints a different picture.

      Vitamin C can actually improve overall performance when taken pre workout.[18] Another study suggests Vitamin C augments nitric oxide production,[19] by preserving the mechanisms of the Nitric Oxide Synthase enzyme (eNOS). Basically this improves overall NO production in the body further increasing pumps and vascularity.

      It’s also synergistic with the nitrates in creatine nitrate above.

      Note: Some labels online are out of date – they should state that there is 300mg Vitamin C from this product, as confirmed by APS.

    • Creatinol-O-Phosphate

      This image was posted to APS Instagram account. Could this be new labeling for the newly high-powered Mesomorph?

      This image was posted to APS Instagram account. Could this be new labeling for the newly high-powered Mesomorph?

      Creatinol-O-Phosphate (COP) is a great ingredient for increasing athletic performance and endurance that acts as a lactic acid buffer, similar to beta alanine. Additionally, COP contributes a phosphate-group back to the ATP process, which increases creatine’s effects.

      Unfortunately, there isn’t a ton of research confirming the benefits of COP currently.  Hopefully this changes soon, as more products coming to market seem to be including this endurance maximizer.

    • Agmatine Sulfate

      Amatine sulfate is another well-known nitric oxide booster and neurotransmitter in the body that inhibits the breakdown of NO in the body.[20] Since it’s also a neurotransmitter and neuromodulator, Agmatine Sulfate can also aid with focus and during your gym sessions.[21]

      The usual dose in a pre workout is 500mg, but we’re not quite sure how much is in Mesomorph. However, the combination of Citrulline Malate, Taurine, Creatine Nitrate, AAKG, and Agmatine should deliver some very respectable pumps.

  • Neuromorph-Neuro Energized Stimulant Matrix (1.87g)

    • Glucuronolactone

      Glucuronolactone is a metabolite of glucose that helps regulate the formation of glycogen in the body. It’s included in nearly every energy drink, and quite a few pre workouts, but has very little, if any research on it, and makes us wonder why it’s used so frequently.

      After talking with APS, we got some clarification on why they chose to include it in Mesomorph:

      “Most people think it has an energy component but we use it with the vitamin C as an exercise enhancer to improve people’s overall performance and recovery due to its anti-oxidant value.”

      One study has been published showing glucuronolactone to be an ergogenic ingredient. While the study was conducted on animals, the human equivalent dose (1-2g) should improve endurance capacity.[37]

      The amount included in Mesomorph is 1.3g, whereas the standard can of Red Bull only contains roughly 600mg of the compound.

    • Caffeine Anhydrous (300mg)

      Here’s a real energy booster all pre workouts should contain. Caffeine has been shown over and over and over to improve mood, focus, performance, and endurance.[22,23]

      While we don’t know the dose, the combination of caffeine and our next ingredient should be all the energy you need. It may be prudent to even start with a ½ scoop to assess reaction right out of the gate.

      It’s not on the label, but we’ve received confirmation that there’s 300mg caffeine in a full scoop of Mesomorph.

      The 300mg caffeine / 65mg DMAA is basically the perfect amount of energy for most advanced athletes – but if you need less, running 2/3 scoop is a good idea.

    • Theobromine

      Theobromine comes from cocoa and often associated with that quintessential “feel-good” sensation many experience when eating dark chocolate. Aside from improving your mood, it also imparts a mild stimulatory effect, similar to caffeine, but has a smoother more prolonged effect.[24]

      When combined with caffeine and the other stims still to come, theobromine helps smooth out any crash or “bottoming out” some experience when ingesting high amounts of caffeine. Basically, you can stay energized longer and enjoy a smooth ride down from the energy high in the ensuing hours.

    • Naringin

      Naringin is a compound found in grapefruits that’s gained notoriety as being beneficial for diabetics and lowering blood pressure.[25,26]

      There is some thought that it may improve energy levels and weight loss, but the research is mixed. We’ve seen great success with it in a few fat burners, but haven’t always felt it. It does, however, seem to come along with the next ingredient quite frequently:

    • Geranaburn (providing 65mg DMAA)

      Rocket Pop is the newest flavor for Mesomorph...will it taste like everyone's favorite treat from the Ice Cream Man?

      Rocket Pop is the newest flavor for Mesomorph… and we can confirm that it does taste like everyone’s favorite popsicle from the old ice cream truck!

      Geranium Oil Extract, a.k.a. DMAA (1,3 dimethylamylamine), has made its glorious return to the land of pre workouts and fat burners.

      Bringing the focus, athletic prowess, and endurance

      The good news is that this potent CNS stimulant gives unstoppable focus, energy, athletic endurance, and even appetite suppression for dieters. It was most well-known for its use in Jack3d, OxyELITE Pro, and the Lipodrene fat burner. Over the years, USPLabs commissioned seven safety studies showing its effectiveness and safety in healthy individuals.[27,28,29,30,31,32,33]

      The most important thing to note that at a 75mg dose, it also increases blood pressure without raising heart rate,[34] which is one reason why we personally love this ingredient in the 25-50mg dose.

      Although the energy complex used in Mesomorph is a proprietary blend, the APS disclosed that there is 65mg per scoop. This is a fairly hefty dose, especially for beginners. So, as we mentioned above, it’d be wise to start with ½-¾ scoop if this is your first time using DMAA and caffeine together in a pre workout, and watch your socks get knocked off by this stuff!

      More info on 1,3

      You can see the full DMAA Supplement List, which is dominated by Hi-Tech Pharmaceuticals and APS Nutrition. If you’re interested in the entire legal saga, with updates from 2015, see the ongoing lawsuit updates here.

      The short story is that Hi-Tech claims that it is a legal and compliant dietary supplement found in geranium plants, and that the FDA’s warning letters (which were ironically never sent to Hi-Tech) do not constitute “final agency action” — warning letters do NOT equal a true “ban” on a legal substance!

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APS Mesomorph Review: CJ and Amin’s Video Review on YouTube

CJ and Amin had the great experience of testing this high-energy pre workout and totally loved it. CJ ended up liking a full scoop, whereas Amin, after a few more uses, settles on 2/3-3/4 scoop like Mike does:

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Flavors Available

APS Mesomorph Tutti Frutti

Remember that Tutti Frutti gum flavor growing up? Now you can get it for the first time ever — only in the #1 pre workout supplement!!

Each tub of APS Mesomorph packs 25 servings and is available in 6 flavors:

  • Tropical Punch
  • Grape
  • Pineapple
  • Rocket Pop
  • Watermelon
  • Pink Lemonade
  • Tutti Frutti

Since its release, Rocket Pop has been the best seller (by far), but the June 2016 release of Tutti Frutti has been one of the best and most exciting ever — tutti frutti may give rocket pop a run for its money! Try both on your next run!

Takeaway

Mesomorph is a well-rounded, crazy high-powered pre workout that will give you all the energy and focus that you could ask for – and then some!

APS Nutrition claims Mesomorph as the “King” of pre workout products on the market with full clinical-doses of the ingredients included in it. We just have to wonder why they only use proprietary blends if there’s nothing to hide?

Either way, if you’re here, you’re probably here for the extreme energy and focus, and you sure are going to get it with Mesomorph. Game over.

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Donating to research in October 2015

APS Mesomorph Contest

APS is donating serious money to breast cancer research too, with a weekly contest to give away two free tubs each Friday in October!

In case you didn’t know, APS is donating $1.00 per bottle sold for breast cancer research when they ran their batch of the new Pink Lemonade flavor in October of 2015 – and they’re planning on running a batch well into the thousands!

See the image to the side, where they’re running contests every Friday on PricePlow in October 2015 to give away two free pink lemonade tubs at a time!!

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References

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  2. Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training
  3. Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
  4. Wilson GJ1, Layman DK, Moulton CJ, Norton LE, Anthony TG, Proud CG, Rupassara SI, Garlick PJ. Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats. Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1236-42
  5. Bailey SJ, Blackwell JR, Lord T, Vanhatalo A, Winyard PG, Jones AM. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans. J Appl Physiol (1985). 2015 Aug 15;119(4):385-95
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010 May;24(5):1215-22.
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  8. Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
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  11. Bemben, M; The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.; Neuromuscular Lab, Dept. Health & Exercise Science, U. Oklahoma; 2010
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  14. Hoffmann, E.K., I.H. Lambert, and S.F. Pedersen, Physiology of cell volume regulation in vertebrates. Physiol Rev, 2009. 89(1)
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  18. Paschilis, V. et al. Low vitamin C values are linked with decreased physical performance and increased oxidative stress: reversal by vitamin C supplementation Eur J Nutr (2014)
  19. Heller R, et al L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells . J Biol Chem. (1999)
  20. Demady, D; Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme.; Department of Pharmacology, The University of Michigan Medical School; 2001
  21. Lu Y, Christian K, Lu B; BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory . Neurobiol Learn Mem. (2008)
  22. Backhouse, SH, et. al; Appetite; “Caffeine ingestion, affect and perceived exertion during prolonged cycling;” August 2011
  23. Hurley, CF; Journal of Strength and Conditioning Research; “The effect of caffeine ingestion on delayed onset muscle soreness;” November 2013
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  29. Farney TM, McCarthy, CG, Canale R et al.; “Hemodynamic and Hematologic Profile of Healthy Adults Ingesting Dietary Supplements Containing 1,3-Dimethylamylamine and Caffeine”; Nutrition and Metabolic Insights; 2012:5 1-12; Available at https://blog.priceplow.com/wp-content/uploads/hemodynamic-and-hematologic-profile-of-healthy-adults-ingesting-dietary-supplements-containing-1-3-dimethylamylamine-and-caffeine.pdf
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  • Tom00436

    I tried contacting APS to find out the Creatine content. Unfortunately I did not hear back from them. I really don’t like the prop. label, but it’s worked well enough for me to stick with Mesomorph. I want to add creatine to it, but was wondering how much total creatine in all its forms was in it to begin with. Do you think you could reach out to them, Mike? It seems like they gave you some info with some of the amounts when you emailed them in the past.

  • demardorsey

    I remember back 4 years ago with Jack3d and ACG3, those Pre-workouts would get me in the zone. I was a little skeptical with Mesomorph because I hadn’t had any DMAA in my system in almost 4 years, so I took a half a scoop, then 5 minutes later another half…Didn’t really feel anything. Today I went with a full scoop, and feel the same. Not sure if there’s 64mg of DMAA per scoop. In fact, it’s 8:32 am on a Sunday, I’m going to go back to sleep

    • Did you buy the older “V2” version without DMAA?

      • demardorsey

        I have the rocket pop flavor, and the last ingredient says “gernaburn (1.3 dymethalalnine HCL)”

      • Right, that’s definitely got DMAA. Everyone else is loving it, not sure what’s up for you. Not everyone likes the ingredient… maybe something’s changed for you?

  • Ross80

    I don’t get a pump from this product using 1 scoop, at all. I use the DMAA Rocketpop flavor. I got a pump from White Rapids, but not White Pipes. I also get a pump from old Hypermax XT with 2 scoops. I’d like to try the new Hypermax XT.