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APS Mesomorph – DMAA Removed!!!

APS Mesomorph

With the fate of DMAA still in question, APS and Hi-Tech have reformulated Mesomorph to now contain Senegalia Berlandieri and Isopropylnorsynephrine.

For a long time, DMAA was taboo in pre workouts due to ongoing litigation between the U.S. Government and the supplement companies themselves. Then Hi-Tech took up the people’s fight and got DMAA back in pre workouts, but once again the dark side has re-emerged and temporarily banned the wonder stim from dietary supplements.

As sad and depressed as that may make some of you, all hope is not lost, because just when things looked their bleakest Hi-Tech and APS Nutrition went back to the drawing board and came up with a revamped (and possibly more intense) version of the strongest pre workout on the market —  Mesomorph

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Mesomorph Ingredients

Mesomorph uses 3 different proprietary blends to get you amped up for your impending lift session. Although APS / Hi-Tech have been forced to remove DMAA, they’ve added in two other potent stimulants to up the intensity and feel good effects of this top pre workout.

  • Synthenox-Carnosine / Nitric Oxide Complex (6.5g)

  • Mesoswell-Cell Volumizing ATP Matrix (4.5mg)

    • Di-Creatine Malate

      Creatine Solubility

      Many think creatine nitrate is better than monohydrate due to its higher solubility, but there are no studies validating its effectiveness over mono.

      Creatine Malate is a novel form of creatine that binds the compound to malic acid, similar to citrulline malate. This is done to help improve the bioavailability of creatine ensuring it is readily absorbed by the muscles and not broken down in the stomach to the useless byproduct, creatinine.

      Creatine malate claims to confer all the strength and power benefits of creatine supplementation[11,12] with none of the “bloat” that’s sometimes seen with monohydrate use. Malic acid also helps improve endurance by acting as a buffer in your muscles, similar to what occurs with citrulline malate.[13]

    • Taurine

      Taurine is an incredibly abundant amino acid in the body that’s mainly stored in the muscles, heart, and brain. Typically, there are usually ample amounts of taurine in the body, but during periods of intense exercise, the body can’t produce enough to meet demand, thus making it “conditionally essential.”

      Taurine helps pull water and nutrients, thereby acting as a cell volumizer.[14] Overall, you’ll experience better pumps and reduced delayed onset muscle soreness when supplementing with it.[15]

    • Creatine Nitrate

      Here we have another creatine hybrid that further improves pumps due to its nitrate component. A lot of the bros in the community believe creatine nitrate to be superior monohydrate due to its increased water solubility, which theoretically yields better absorption.

      If you’re here, you’re probably here for the extreme energy and focus, and you sure are going to get it with Mesomorph. Game over.

      However, no current studies on creatine nitrate exist showing it superior to monohydrate in terms of strength, body composition, or athletic performance.

      With that said, the nitrate portion of this molecule will definitely lead to increased pumps – especially since we know it’s at least 300mg worth, a great start for a nitrate compound. Creatine Nitrate is roughly 67.5% creatine, 32.5% nitrate.

      Nitrate synergy with arginine

      To top it off, the nitrate will definitely work very well alongside the arginine up above, making the nitric oxide boost last longer too.[35,36]

    • Ascorbic Acid (300mg Vitamin C)

      More commonly known as Vitamin C, ascorbic acid is a water-soluble vitamin and powerful antioxidant in the body. While early research showed that high doses of antioxidant decreased athletic performance,[16,17] there is so other research that paints a different picture.

      Vitamin C can actually improve overall performance when taken pre workout.[18] Another study suggests Vitamin C augments nitric oxide production,[19] by preserving the mechanisms of the Nitric Oxide Synthase enzyme (eNOS). Basically this improves overall NO production in the body further increasing pumps and vascularity.

      It’s also synergistic with the nitrates in creatine nitrate above.

      Note: Some labels online are out of date – they should state that there is 300mg Vitamin C from this product, as confirmed by APS.

    • Creatinol-O-Phosphate

      APS Mesomorph Stack

      With so many flavor options of Mesomorph available, which will you choose?

      Creatinol-O-Phosphate (COP) is a great ingredient for increasing athletic performance and endurance that acts as a lactic acid buffer, similar to beta alanine. Additionally, COP contributes a phosphate-group back to the ATP process, which increases creatine’s effects.

      Unfortunately, there isn’t a ton of research confirming the benefits of COP currently.  Hopefully this changes soon, as more products coming to market seem to, be including this endurance maximizer.

    • Agmatine Sulfate

      Amatine sulfate is another well-known nitric oxide booster and neurotransmitter in the body that inhibits the breakdown of NO in the body.[20] Since it’s also a neurotransmitter and neuromodulator, Agmatine Sulfate can also aid with focus and during your gym sessions.[21]

      The usual dose in a pre workout is 500mg, but we’re not quite sure how much is in Mesomorph. However, the combination of Citrulline Malate, Taurine, Creatine Nitrate, AAKG, and Agmatine should deliver some very respectable pumps.

  • Neuromorph-Neuro Energized Stimulant Matrix (1.87g)

    • Glucuronolactone

      Glucuronolactone is a metabolite of glucose that helps regulate the formation of glycogen in the body. It’s included in nearly every energy drink, and quite a few pre workouts, but has very little, if any research on it, and makes us wonder why it’s used so frequently.

      After talking with APS, we got some clarification on why they chose to include it in Mesomorph:

      “Most people think it has an energy component but we use it with the vitamin C as an exercise enhancer to improve people’s overall performance and recovery due to its anti-oxidant value.”

      One study has been published showing glucuronolactone to be an ergogenic ingredient. While the study was conducted on animals, the human equivalent dose (1-2g) should improve endurance capacity.[37]

      The amount included in Mesomorph is 1.3g, whereas the standard can of Red Bull only contains roughly 600mg of the compound.

    • Caffeine Anhydrous (300mg)

      Here’s a real energy booster all pre workouts should contain. Caffeine has been shown over and over and over to improve mood, focus, performance, and endurance.[22,23]

      Mesomorph packs a robust 300mg caffeine anhydrous per scoop, which is quite a hit of caffeine for most, but minuscule for others addicted to energy drinks, coffee, and pre workouts. Whatever your caffeine tolerance, Mesomorph’s litany of other stimulants definitely adds extra “oomph” so that you’ll never need more than a full scoop.

    • Senegalia Berlandieri

      Acacia Rigidula Research

      On its own, 250mg Acacia Rigidula outperforms 30mg ephedrine in VO2 testing. Senegalia Berlandieri is extremely similar to this acacia.

      The first of the two ingredients added into the updated version of Mesomorph to replace DMAA is Senegalia Berlandieri, an extract extremely similar to Acacia Rigidula. Senegalia extract is standardized to provide 200mg worth of several PEA alkaloids including N-Phenethyldimethylamine, B-Phenylethylamine, and N-Methyl-B-Phenylethylamine.

      This mood-boosting ingredient promotes greater dopamine and adrenaline levels in the body which should substantially enhance energy too. Research using acacia extract (which this basically is) demonstrates that it boasts the same fat-burning, energy boosting effects as 30mg of ephedrine.[27,28]

    • Theobromine

      Theobromine comes from cocoa and often associated with that quintessential “feel-good” sensation many experience when eating dark chocolate. Aside from improving your mood, it also imparts a mild stimulatory effect, similar to caffeine, but has a smoother more prolonged effect.[24]

      When combined with caffeine and the other stims still to come, theobromine helps smooth out any crash or “bottoming out” some experience when ingesting high amounts of caffeine. Basically, you can stay energized longer and enjoy a smooth ride down from the energy high in the ensuing hours.

    • Naringin

      APS Mesomorph King

      For a long time, Mesomorph has reigned supreme as the King of Pre workouts, but now that DMAA is gone, will it still rate at the top?

      Naringin is a compound found in grapefruits that’s gained notoriety as being beneficial for diabetics and lowering blood pressure.[25,26]

      There is some thought that it may improve energy levels and weight loss, but the research is mixed. We’ve seen great success with it in a few fat burners, but haven’t always felt it. It does, however, seem to come along with the next ingredient quite frequently:

    • Isopropylnorsynephrine

      The final ingredient of the new edition of Mesomorph is an isopropyl derivative of a well known fat loss agent present in citrus aurantium, synephrine. Isopropylnorsynephrine is an incredibly potent fat loss agent.[33] Studies note the compound is “active at 1 μg/ml and reproducing more than 60% of isoprenaline maximal effect in human adipocytes”.[33]

      In fact, this novel stimulant is so potent that it’s been touted by some as the strongest stimulant on a mg/mg basis ever!

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APS Mesomorph with DMAA Review: CJ and Amin’s Video Review on YouTube

CJ and Amin had the great experience of testing this high-energy pre workout and totally loved it. CJ ended up liking a full scoop, whereas Amin, after a few more uses, settles on 2/3-3/4 scoop like Mike does:

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Flavors Available

Each tub of APS Mesomorph packs 25 servings and is available in 10 flavors:

APS Mesomorph Tutti Frutti

Remember that Tutti Frutti gum flavor growing up? Now you can get it for the first time ever — only in the #1 pre workout supplement!!

  • Tropical Punch
  • Grape
  • Pineapple
  • Rocket Pop
  • Watermelon
  • Tutti Frutti
  • Carnival Cotton Candy
  • Pink Lemonade
  • Green Apple Candy
  • Snow Cone

Takeaway

Mesomorph is a well-rounded, crazy high-powered pre workout that will give you all the energy and focus that you could ask for – and then some!

APS Nutrition claims Mesomorph as the “King” of pre workout products on the market with full clinical-doses of the ingredients included in it. We just have to wonder why they only use proprietary blends if there’s nothing to hide?

Either way, if you’re here, you’re probably here for the extreme energy and focus, and you sure are going to get it with Mesomorph. But is it as good as the DMAA version? We’ll have to wait and see!

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Posts are sponsored in part by the retailers and/or brands listed on this page.

References

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References

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  2. Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training
  3. Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
  4. Wilson GJ1, Layman DK, Moulton CJ, Norton LE, Anthony TG, Proud CG, Rupassara SI, Garlick PJ. Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats. Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1236-42
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  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010 May;24(5):1215-22.
  7. Osowska S, Duchemann T, Walrand S, Paillard A, Boirie Y, Cynober L, Moinard C. Citrulline modulates muscle protein metabolism in old malnourished rats. Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E582-6.
  8. Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
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  10. http://www.ncbi.nlm.nih.gov/pubmed/19033611
  11. Bemben, M; The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.; Neuromuscular Lab, Dept. Health & Exercise Science, U. Oklahoma; 2010
  12. Chilibeck, P; Effect of creatine ingestion after exercise on muscle thickness in males and females.; College of Kinesiology, University of Saskatchewan; 2004
  13. Giannesini B., et. al.; European Journal of Pharmacology; “Citrulline malate supplementation increases muscle efficiency in rat skeletal muscle;” September 2011
  14. Hoffmann, E.K., I.H. Lambert, and S.F. Pedersen, Physiology of cell volume regulation in vertebrates. Physiol Rev, 2009. 89(1)
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  16. http://www.ncbi.nlm.nih.gov/pubmed/23878368
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  18. Paschilis, V. et al. Low vitamin C values are linked with decreased physical performance and increased oxidative stress: reversal by vitamin C supplementation Eur J Nutr (2014)
  19. Heller R, et al L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells . J Biol Chem. (1999)
  20. Demady, D; Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme.; Department of Pharmacology, The University of Michigan Medical School; 2001
  21. Lu Y, Christian K, Lu B; BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory . Neurobiol Learn Mem. (2008)
  22. Backhouse, SH, et. al; Appetite; “Caffeine ingestion, affect and perceived exertion during prolonged cycling;” August 2011
  23. Hurley, CF; Journal of Strength and Conditioning Research; “The effect of caffeine ingestion on delayed onset muscle soreness;” November 2013
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  26. http://www.ncbi.nlm.nih.gov/pubmed/19153985
  27. Jacobs, Patrick, PhD; “The Acute Metabolic, Hemodynamic, and Psychological Effects of Fastin-XR, a Commercial Weight Loss Product”; Retrieved from http://origin-qps.onstreammedia.com/origin/multivu_archive/ENR/Acacia-Fastin-XR-study.pdf (backed up at http://www.webcitation.org/6cZhHyG6V)
  28. Jacobs, Patrick; “The Acute Physiological Effects of Acacia Rigidula”; Presentation at the 2012 Arnold Sports Festival; March 2012; Retrieved from http://origin-qps.onstreammedia.com/origin/multivu_archive/ENR/TheAcutePhysiologicalEffectsofAcaciaRigidula.pdf(backed up at http://www.webcitation.org/6e8bE22ix)
  29. Removed
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  33. https://www.ncbi.nlm.nih.gov/pubmed/21336650
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  37. http://www.ncbi.nlm.nih.gov/pubmed/5302458
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