5% Nutrition Digestive Defender: A 2-in-1 Gut Health Supplement Kit

If you’re gunning to be anywhere near the size of legendary bodybuilder and modern renaissance man Rich Piana, then you’re going to need to eat a lot of food. An absurd amount – and have a training regimen to follow.

However, your body can’t utilize what it can’t absorb. Regardless of the Kill It-inspired level 9000 training intensity and ten-ingredient creatine supplements like Crea-TEN, if your body’s gut isn’t doing well or can’t properly break down and digest proteins… you’re not going to maximize your potential.

5% Nutrition Digestive Defender

5% Nutrition Digestive Defender is actually two supplements in one kit, all built to protect gut health for those massive Rich Piana style meals!

5% Nutrition has a new kit that’s actually a pair of supplements to help with your gut health and digestion:

5% Nutrition’s Digestive Defender: Two Supplements in One Package

Meet the unique Digestive Defender package from 5% Nutrition, which actually contains two different products:

  • Probio-75 – A probiotic supplement with a massive 75 Billion CFU dosage
  • Diges-TEN – A digestive enzyme supplement

In this article, we break down both supplements in two different sections. 5% Nutrition’s kept us busy, so before we get into the details, check our coupon-powered prices below and sign up for our 5% Nutrition news:

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Digestive Defender: Two Supplements in One Package

5% Nutrition Digestive Defender

Two supplements in one!

Again, Digestive Defender is two different products:

Both come in two capsule servings and are meant to be taken once daily, with or without food. They are covered individually below:

5% Nutrition Probio-75 Ingredients

5% Nutrition’s probiotic + prebiotic + gut health blend brings the following in two capsules:

  • SL14 Probiotics Blend – 75 Billion CFU

    SL14 is a probiotic blend that includes a long list of strains: Lactobacillus acidophilus, Bifidobacterium breve, Lactobacillus fermentum, Lactobacillus rhamnosus, Lactobacillus gasseri, Lactobacillus plantarum, Bifidobacterium lactis, Lactobacillus casei, Lactobacillus paracasei, Lactobacillus salivarius, Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium infantis, and Streptococcus thermophilus.

    5 Percent Nutrition Probio-75 Ingredients

    Probio-75 has a huge 75 Billion CFU dose of probiotics!

    While we can’t dig into the research on every last component, we can comment on their general effects. First, it’s important to define probiotics as living microorganisms that consist of healthy bacteria and help restore beneficial bacteria levels in the gut.[1] Different strains have different metabolisms of their own, leading to different benefits inside of your gut.

    The measurement unit “CFU” stands for colony forming units, which tells us the total number of viable cells inside at the time of manufacturing.[2,3] As always with 5% Nutrition, Rich Piana’s brand has a “go big or go home” attitude, with a massive number of viable cells that’s 3-4x larger than the average supplement we see!

    Probio-75 primarily includes two of the most common families of probiotics, Lactobacillus and Bifidobacterium.[1]

    • Lactobacillus

      The lactobacillus family treats numerous conditions, including (but not limited to):

      • Assists with digestive disorders like IBS, ulcerative colitis, and Crohn’s disease[4-7]
      • Immune system improvements[8,9]
      • Increases ATP generation (better cellular energy)[10]
      • Improves antioxidant status[11]
      • Cholesterol reduction[12]
      • Lung and inflammation conditions[13]
      • Improved dental health[14]
      • Skin condition improvements[15]
    • Bifidobacterium

      Rich Piana Livin the Dream

      “You gotta eat big to get big!”

      The bifidobacterium family has been shown to help more specific gut issues:

      • Reduction of diarrhea, gas, IBS, and allergies[16,17]
      • Less bloating and reduced abdominal discomfort[18]
      • Better overall digestion and mineral uptake[19,20]
      • Useful against ulcerative colitis[21,22]
      • Immunity support[23]
      • Helps treat lung infections (and other inflammatory problems)[13,24]
    • Streptococcus thermophilus

      Finally, there’s also Streptococcus thermophilus, which has been demonstrated to be effective against severe colorectal diseases.[25]

    All in all, this is a fantastic blend at a huge dosage.

  • Prebiotic Blend

    Alongside the probiotics are the prebiotics, which provide fuel for the gut bacteria to utilize.[26] 5% Nutrition includes the following:

    • Fructooligosaccharides (NUTRAFLORA FB P-95) – 400mg

      Fructooligosaccharides (also known as oligofructose or FOS) are non-digestible carbohydrates with unique structural properties that help the gut generate more short-chain fatty acids,[27] which are massively important to gut health.

      Rich Piana Whatever It Takes

      Whatever it takes to keep your gut healthy!

      In addition, they help improve mineral absorption,[28-31] which can greatly increase other areas of health such as bone mineral density.[28,32] In terms of gut health, it’s the method that’s useful — FOS reduce colon pH.

      In general, FOS has been shown to improve blood sugar levels, lipid profiles, and lower general disease risk.[27]

    • Xylooligosaccharide (PreticX 95%)

      PreticX is a unique xylooligosaccharide (XOS) prebiotic supplement ingredient that also helps feed the existing probiotic bacteria to promote a better and more balanced gut microflora.[33] Animal models have shown that XOS also increases short-chain fatty acids, concluding that “XOS can alleviate colonic inflammation by regulating gut microbial composition and enhancing SCFA content in the gut.”[34]

  • Gut Health Blend

    Probio-75 doesn’t only have prebiotics and probiotics, there are also some traditional herbal dietary supplement ingredients included as well!

    • Ginger Root Extract (5% Gingerols) – 50 mg

      Long used to treat gut issues (and used by Mom in the form of ginger ale), ginger actually works incredibly well in treating nausea.[35-45]

      Ginger Supplements

      We’ve long known about ginger’s anti-nausea, anti-inflammatory benefits

      It works by speeding up the gastric transit of food in the digestive system,[46] helping nauseous users get over their sickness more quickly. Additionally, ginger often helps lower flatulence (gas) by breaking up the gas and reducing pressure in the lower esophageal sphincter.[47]

    • Licorice Root Extract 4:1 – 50 mg

      Licorice root is another herbal ingredient that’s traditionally used to treat gastrointestinal issues. It has been demonstrated to improve digestion and reduce nausea,[48] reduce gut-born infections,[49] and even reduce ulcers.[50]

    • Peppermint Powder – 25 mg

      The third in the trio of traditional ingredients in Probio-75, peppermint has been used to treat IBS and abdominal pain,[51,52] making for a perfect final addition to the supplement. It may also improve the smell of the capsules, which is never a bad thing.

Diges-TEN Ingredients

In two caps, you get the following digestive support complex:

  • Dynamic Digestion Blend

    • Betaine Hydrochloride – 100 mg

      5% Nutrition Diges-TEN Ingredients

      Diges-TEN is no standard digestive enzyme supplement, but has many of nature’s best ingredients too!

      Far different from the betaine anhydrous you see in ergogenic pre-workout supplements, betaine hydrochloride is used for the “re-acidification” of the gastrointestinal system by lowering gastric pH.[53] Betaine HCl is very acidic, and this is a good thing – indigestion often occurs when acid is too low, although too many treat it as if it feels too high.

      Hydrochloric acid (HCl) is an acid produced in the stomach naturally that activates pepsin.[54] This keeps a healthy gut flora balance, and you don’t want to be low on this critical molecule.

    • Ox Bile (Bovine) – 100 mg

      Ox bile is used to help the gallbladder with the processing of fats (and this is actually a critical supplement that many take if they’ve had their gallbladder removed).[55]

      There are numerous types of animal bile, but ox bile has always been an easily-harvested and readily-available source that works incredibly well in humans.

  • Protein Breakdown Blend

    We often see protease in digestive enzyme blends, but 5% Nutrition takes it further with the following collection of four different types:

    • Proteases – 152 mg

      The “standard” protein digestive enzymes used to improve protein breakdown, digestion, and absorption. They even can help reduce the damaging effects from hard exercise and muscle soreness, improving recovery.[56,57]

    • Bromelain – 150 mg

      Protease Post Workout

      Could Protease help with post workout soreness and recovery? Research indicates it can!

      Bromelain is an enzyme found in pineapples that helps assist protein digestion (this is often why pineapple is paired with meat in native / traditional cooking in warm climates). It allows for better absorption through the intestines and helps improve antioxidant absorption and activity.[58,59]

      You often see it in anti-inflammatory supplements since it’s been shown to reduce knee pain,[60] and it’s also in allergy supplements since it can help with sinus issues as well.[61]

    • Pancreatin – 65 mg

      Pancreatin is actually a mixture of amylases, proteases, and lipases made by the pancreas when digesting food.[62] It includes a protease named trypsin, which is good for hydrolyzing additional types of proteins.

    • Papain – 65 mg

      Another fruit-borne protease in Diges-TEN, papain is most commonly found in papaya, another fruit that’s used to cook meat. It has numerous uses (including teeth whitening[63] and drug-test adulteration![64]) but for our case, it greatly assists protein digestion (especially with certain types of ulcers) and is also known as papaya proteinase I.[65]

  • Carbohydrate Breakdown – Amylase – 108 mg

    Rich Piana Cereal

    Never miss a meal!

    Amylase is an enzyme that breaks down carbohydrates, and it’s actually found in the saliva where it immediately begins to cleave starches into more simple sugars.[66] Although it’s also found in the intestine, it goes to show that digestion begins in your mouth, so chew your food properly!

  • Fat Breakdown – Lipase – 70 mg

    Working with the ox bile is lipase, the digestive enzyme that assists with lipid digestion.[67]

  • Fiber Breakdown – Cellulase – 26 mg

    Plant fibers such as cellulose are often difficult to digest, and cellulase assists with those. They break the cellulose molecule down into monosaccharides, which are simple sugars.

  • Milk Sugar (Lactose) Breakdown – Lactase – 43 mg

    Anyone who’s lactose sensitive knows that adding some lactase, the digestive enzyme that breaks down lactose, can greatly reduce GI issues, as lactose intolerance is sometimes caused simply by lactase deficiency.[68]

    This may help you digest dairy far better, although it likely won’t help those who are strongly or severely lactose intolerant.

  • Digest Best Blend – 190 mg

    The Digest Best Blend includes Ginger Root, Turmeric Powder, Organic Apple Cider Vinegar, Cayenne Pepper Fruit Extract, and Artichoke Leaf Powder.

    We covered ginger in the Probio-75 section, and it’s great to see more of it included. Apple cider vinegar is often used for its acidic content, helpful alongside betaine HCl when acid levels are too low.

    Every time we write about artichoke leaf extract, we come away impressed. It’s been shown to improve lipid levels by safely increasing HDL cholesterol (where pharmaceuticals have failed), but also has long-standing use for digestive and bowel problems.[69]

5% Nutrition Digestive Defender Ingredients

A recap of both labels


As mentioned above, both supplements come in their own bottles, and each is a two capsule serving. You can take them all at once, but if you do AM/PM supplement dosing, you could also consider splitting them into one capsule of each at a time.

Digestive Defender Hits all Angles

Rich Piana Freak Show

Love carbs and need to drive them home? Then join the FREAK SHOW

As always, 5% Nutrition employs the “go big or go home” route, with a massively dosed probiotic supplement in Probio-75. Too many of these supplements ignore digestive enzymes, or underdose them, but Diges-TEN brings them in a big way by adding additional natural ingredients like papain and bromelain, which we’re not seeing too frequently in the plethora of gut health supplements released lately.

As covered in our 5% Nutrition news page, this brand is insanely busy, and we repeatedly state that Rich Piana would be incredibly proud — and we absolutely mean that.

You can’t absorb and utilize what you can’t digest, so if you don’t think you’re getting the most from your diet, then consider going all in with the 5% Nutrition’s Digestive Defender to hit prebiotics, probiotics, digestive enzymes, and everything in between.

Rich Piana 5% Nutrition Digestive Defender – Deals and Price Drop Alerts

Get Price Alerts

No spam, no scams.

Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public. Mike is currently experimenting with a low Vitamin A diet.

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  1. National Center for Complementary and Integrative Health. “Probiotics: What You Need to Know.” NCCIH, Aug. 2019; https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know
  2. National Institutes of Health; Office of Dietary Supplements; “Probiotics”; https://ods.od.nih.gov/factsheets/Probiotics-HealthProfessional/
  3. United States Food and Drug Administration; “Policy Regarding Quantitative Labeling of Dietary Supplements Containing Live Microbials: Guidance for Industry”; September 2018; https://web.archive.org/web/20210303020741/https://www.fda.gov/media/115730/download
  4. María Remes Troche, José, et al. “Lactobacillus Acidophilus LB: A Useful Pharmabiotic for the Treatment of Digestive Disorders.” Therapeutic Advances in Gastroenterology, vol. 13, 24 Nov. 2020, 10.1177/1756284820971201; https://journals.sagepub.com/doi/10.1177/1756284820971201
  5. Rönkä, Elina, et al. “Probiotic and Milk Technological Properties of Lactobacillus Brevis.” International Journal of Food Microbiology, vol. 83, no. 1, May 2003, pp. 63–74, 10.1016/s0168-1605(02)00315-x; https://pubmed.ncbi.nlm.nih.gov/12672593/
  6. Oberhelman, Richard A., et al. “A Phase One Safety Study of Lactobacillus Reuteri Conducted in the Peruvian Amazon: Observations from the Field.” The American Journal of Tropical Medicine and Hygiene, vol. 90, no. 4, 2 Apr. 2014, pp. 777–780, 10.4269/ajtmh.13-0639; https://www.ajtmh.org/view/journals/tpmd/90/4/article-p777.xml
  7. Oliveira, Manuel, et al. “Lactobacillus Paracasei Reduces Intestinal Inflammation in Adoptive Transfer Mouse Model of Experimental Colitis.” Clinical and Developmental Immunology, vol. 2011, 2011, pp. 1–13, 10.1155/2011/807483; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145352/
  8. Goto, Hiroaki, et al. “Anti-Influenza Virus Effects of Both Live and Non-Live Lactobacillus Acidophilus L-92 Accompanied by the Activation of Innate Immunity.” The British Journal of Nutrition, vol. 110, no. 10, 1 Nov. 2013, pp. 1810–1818, 10.1017/S0007114513001104; https://pubmed.ncbi.nlm.nih.gov/23594927/
  9. Mu, Q, et al; “Role of Lactobacillus reuteri in Human Health and Diseases”; Front. Microbiol., 19 April 2018; https://www.frontiersin.org/articles/10.3389/fmicb.2018.00757/full
  10. Pessione, Enrica. “Lactic Acid Bacteria Contribution to Gut Microbiota Complexity: Lights and Shadows.” Frontiers in Cellular and Infection Microbiology, vol. 2, 2012, 10.3389/fcimb.2012.00086; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417654/
  11. Wang, Jing, et al. “Lactobacillus Plantarum Exhibits Antioxidant and Cytoprotective Activities in Porcine Intestinal Epithelial Cells Exposed to Hydrogen Peroxide.” Oxidative Medicine and Cellular Longevity, vol. 2021, 2021, 10.1155/2021/8936907; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349292/
  12. Mishra, V, and D Prasad. “Application of in Vitro Methods for Selection of Strains as Potential Probiotics.” International Journal of Food Microbiology, vol. 103, no. 1, 15 Aug. 2005, pp. 109–115, 10.1016/j.ijfoodmicro.2004.10.047; https://pubmed.ncbi.nlm.nih.gov/16040148/
  13. Sagar, Seil, et al. “Bifidobacterium Breve and Lactobacillus Rhamnosus Treatment Is as Effective as Budesonide at Reducing Inflammation in a Murine Model for Chronic Asthma.” Respiratory Research, vol. 15, no. 1, 2014, p. 46, 10.1186/1465-9921-15-46; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029990/
  14. Mayanagi, Gen, et al. “Probiotic Effects of Orally AdministeredLactobacillus SalivariusWB21-Containing Tablets on Periodontopathic Bacteria: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial.” Journal of Clinical Periodontology, vol. 36, no. 6, June 2009, pp. 506–513, 10.1111/j.1600-051x.2009.01392.x; https://pubmed.ncbi.nlm.nih.gov/19453574/
  15. Holowacz, S., et al. “Lactobacillus SalivariusLA307 AndLactobacillus RhamnosusLA305 Attenuate Skin Inflammation in Mice.” Beneficial Microbes, vol. 9, no. 2, 27 Feb. 2018, pp. 299–309, 10.3920/bm2017.0084; https://pubmed.ncbi.nlm.nih.gov/29409331/
  16. Guglielmetti, S., et al. “Randomised Clinical Trial: Bifidobacterium Bifidum MIMBb75 Significantly Alleviates Irritable Bowel Syndrome and Improves Quality of Life — a Double-Blind, Placebo-Controlled Study.” Alimentary Pharmacology & Therapeutics, vol. 33, no. 10, 21 Mar. 2011, pp. 1123–1132, 10.1111/j.1365-2036.2011.04633.x; https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2011.04633.x
  17. Brenner, Darren M., and William D. Chey. “Bifidobacterium Infantis 35624: A Novel Probiotic for the Treatment of Irritable Bowel Syndrome.” Reviews in Gastroenterological Disorders, vol. 9, no. 1, 2009, pp. 7–15; https://pubmed.ncbi.nlm.nih.gov/19367213/
  18. Ringel-Kulka, Tamar, et al. “Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Evaluate the Benefit of the Probiotic Bifidobacterium Infantis 35624 in Non-Patients with Symptoms of Abdominal Discomfort and Bloating.” American Journal of Gastroenterology, vol. 112, no. 1, Jan. 2017, pp. 145–151, 10.1038/ajg.2016.511; https://pubmed.ncbi.nlm.nih.gov/27845337/
  19. Karakan, Tarkan, et al. “Low-Dose Lactulose as a Prebiotic for Improved Gut Health and Enhanced Mineral Absorption.” Frontiers in Nutrition, vol. 8, 2021, 10.3389/fnut.2021.672925; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353095/
  20. O’Callaghan, Amy, and Douwe van Sinderen. “Bifidobacteria and Their Role as Members of the Human Gut Microbiota.” Frontiers in Microbiology, vol. 7, no. 925, 15 June 2016, 10.3389/fmicb.2016.00925; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908950/
  21. Cui, Hai-hong, et al. “[the Effects of Bifidobacterium on the Intestinal Mucosa of the Patients with Ulcerative Colitis].” Zhonghua Nei Ke Za Zhi, vol. 42, no. 8, 1 Aug. 2003, pp. 554–55; https://pubmed.ncbi.nlm.nih.gov/14505546/
  22. Tamaki, Hiroyuki, et al. “Efficacy of Probiotic Treatment with Bifidobacterium Longum 536 for Induction of Remission in Active Ulcerative Colitis: A Randomized, Double‐Blinded, Placebo‐Controlled Multicenter Trial.” Digestive Endoscopy, vol. 28, no. 1, 2 Nov. 2015, pp. 67–74, 10.1111/den.12553; https://pubmed.ncbi.nlm.nih.gov/26418574/
  23. Arunachalam, K, et al. “Enhancement of Natural Immune Function by Dietary Consumption of Bifidobacterium Lactis (HN019).” European Journal of Clinical Nutrition, vol. 54, no. 3, Mar. 2000, pp. 263–267, 10.1038/sj.ejcn.1600938; https://pubmed.ncbi.nlm.nih.gov/10713750/
  24. Natividad, Jane M. M., et al. “Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium Breve NCC2950.” Applied and Environmental Microbiology, vol. 79, no. 24, 4 Oct. 2013, pp. 7745–7754, 10.1128/aem.02470-13; https://journals.asm.org/doi/10.1128/AEM.02470-13
  25. Li, Qing, et al. “Streptococcus Thermophilus Inhibits Colorectal Tumorigenesis through Secreting β-Galactosidase.” Gastroenterology, vol. 160, no. 4, 1 Mar. 2021, pp. 1179-1193.e14, 10.1053/j.gastro.2020.09.003; https://pubmed.ncbi.nlm.nih.gov/32920015/
  26. Carlson JL, et al; “Health Effects and Sources of Prebiotic Dietary Fiber;” Curr Dev Nutr.; 2018 Jan 29;2(3); https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041804/
  27. Sabater-Molina, M, et al. “Dietary Fructooligosaccharides and Potential Benefits on Health.” Journal of Physiology and Biochemistry, vol. 65, no. 3, 2009, pp. 315–28, 10.1007/BF03180584; https://pubmed.ncbi.nlm.nih.gov/20119826/
  28. Nzeusseu, A; “Inulin and fructo-oligosaccharides differ in their ability to enhance the density of cancellous and cortical bone in the axial and peripheral skeleton of growing rats”; Bone; 38(3):394-9; 2006 Mar; https://www.ncbi.nlm.nih.gov/pubmed/16249132
  29. Ohta, A., et al. “Calcium and Magnesium Absorption from the Colon and Rectum Are Increased in Rats Fed Fructooligosaccharides.” The Journal of Nutrition, vol. 125, no. 9, 1 Sept. 1995, pp. 2417–2424, 10.1093/jn/125.9.2417; https://pubmed.ncbi.nlm.nih.gov/7666261/
  30. Delzenne, N., et al. “Effect of Fermentable Fructo-Oligosaccharides on Mineral, Nitrogen and Energy Digestive Balance in the Rat.” Life Sciences, vol. 57, no. 17, Sept. 1995, pp. 1579–1587, 10.1016/0024-3205(95)02133-4; https://pubmed.ncbi.nlm.nih.gov/7564905/
  31. Sakai, Kensuke, et al. “The Effect of Short Chain Fructooligosaccharides in Promoting Recovery from Post-Gastrectomy Anemia Is Stronger than that of Inulin.” Nutrition Research, vol. 20, no. 3, Mar. 2000, pp. 403–412, 10.1016/s0271-5317(00)00133-0; https://www.sciencedirect.com/science/article/abs/pii/S0271531700001330
  32. Kruger, Marlena C., et al. “The Effect of Fructooligosaccharides with Various Degrees of Polymerization on Calcium Bioavailability in the Growing Rat.” Experimental Biology and Medicine (Maywood, N.J.), vol. 228, no. 6, 1 June 2003, pp. 683–688, 10.1177/153537020322800606; https://pubmed.ncbi.nlm.nih.gov/12773699/
  33. Jain, Ira, et al. “Xylooligosaccharides: An Economical Prebiotic from Agroresidues and Their Health Benefits.” Indian Journal of Experimental Biology, vol. 53, no. 3, 1 Mar. 2015, pp. 131–142; https://pubmed.ncbi.nlm.nih.gov/25872243/
  34. Fei, Yanquan, et al. “Xylooligosaccharide Modulates Gut Microbiota and Alleviates Colonic Inflammation Caused by High Fat Diet Induced Obesity.” Frontiers in Physiology, vol. 10, 22 Jan. 2020, 10.3389/fphys.2019.01601; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987399/
  35. Borrelli, Francesca, et al. “Effectiveness and Safety of Ginger in the Treatment of Pregnancy-Induced Nausea and Vomiting.” Obstetrics & Gynecology, vol. 105, no. 4, Apr. 2005, pp. 849–856, 10.1097/01.aog.0000154890.47642.23; https://pubmed.ncbi.nlm.nih.gov/15802416/
  36. Fischer-Rasmussen, Wiggo, et al. “Ginger Treatment of Hyperemesis Gravidarum.” European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 38, no. 1, Jan. 1991, pp. 19–24, 10.1016/0028-2243(91)90202-v; https://pubmed.ncbi.nlm.nih.gov/1988321/
  37. Smith, Caroline, et al. “A Randomized Controlled Trial of Ginger to Treat Nausea and Vomiting in Pregnancy.” Obstetrics & Gynecology, vol. 103, no. 4, Apr. 2004, pp. 639–645, 10.1097/01.aog.0000118307.19798.ec; https://pubmed.ncbi.nlm.nih.gov/15051552/
  38. Willetts, Karen E., et al. “Effect of a Ginger Extract on Pregnancy-Induced Nausea: A Randomised Controlled Trial.” The Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 43, no. 2, Apr. 2003, pp. 139–144, 10.1046/j.0004-8666.2003.00039.x; https://pubmed.ncbi.nlm.nih.gov/14712970/
  39. Keating, Angela, and Ronald A. Chez. “Ginger Syrup as an Antiemetic in Early Pregnancy.” Alternative Therapies in Health and Medicine, vol. 8, no. 5, 1 Sept. 2002, pp. 89–91; https://pubmed.ncbi.nlm.nih.gov/12233808/
  40. Ernst, E, and M H Pittler. “Efficacy of Ginger for Nausea and Vomiting: A Systematic Review of Randomized Clinical Trials.” British Journal of Anaesthesia, vol. 84, no. 3, Mar. 2000, pp. 367–371, 10.1093/oxfordjournals.bja.a013442; https://pubmed.ncbi.nlm.nih.gov/10793599/
  41. Pillai, Anu Kochanujan, et al. “Anti-Emetic Effect of Ginger Powder versus Placebo as an Add-on Therapy in Children and Young Adults Receiving High Emetogenic Chemotherapy.” Pediatric Blood & Cancer, vol. 56, no. 2, 14 Sept. 2010, pp. 234–238, 10.1002/pbc.22778; https://pubmed.ncbi.nlm.nih.gov/20842754/
  42. Apariman, Sirirat, et al. “Effectiveness of Ginger for Prevention of Nausea and Vomiting after Gynecological Laparoscopy.” Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 89, no. 12, 1 Dec. 2006, pp. 2003–2009; https://pubmed.ncbi.nlm.nih.gov/17214049/
  43. Nanthakomon, Tongta, and Densak Pongrojpaw. “The Efficacy of Ginger in Prevention of Postoperative Nausea and Vomiting after Major Gynecologic Surgery.” Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 89 Suppl 4, 1 Oct. 2006, pp. S130-136; https://pubmed.ncbi.nlm.nih.gov/17725149/
  44. Vutyavanich, T. “Ginger for Nausea and Vomiting in Pregnancy: Randomized, Double-Masked, Placebo-Controlled Trial.” Obstetrics & Gynecology, vol. 97, no. 4, Apr. 2001, pp. 577–582, 10.1016/s0029-7844(00)01228-x; https://pubmed.ncbi.nlm.nih.gov/11275030/
  45. Chaiyakunapruk, Nathorn, et al. “The Efficacy of Ginger for the Prevention of Postoperative Nausea and Vomiting: A Meta-Analysis.” American Journal of Obstetrics and Gynecology, vol. 194, no. 1, Jan. 2006, pp. 95–99, 10.1016/j.ajog.2005.06.046; https://pubmed.ncbi.nlm.nih.gov/16389016/
  46. Wu, Keng-Liang, et al. “Effects of Ginger on Gastric Emptying and Motility in Healthy Humans.” European Journal of Gastroenterology & Hepatology, vol. 20, no. 5, May 2008, pp. 436–440, 10.1097/meg.0b013e3282f4b224; https://pubmed.ncbi.nlm.nih.gov/18403946/
  47. Lohsiriwat, Supatra, et al. “Effect of Ginger on Lower Esophageal Sphincter Pressure.” Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 93, no. 3, 1 Mar. 2010, pp. 366–372; https://pubmed.ncbi.nlm.nih.gov/20420113/
  48. Raveendra, Kadur Ramamurthy, et al. “An Extract of Glycyrrhiza Glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study.” Evidence-Based Complementary and Alternative Medicine : ECAM, vol. 2012, 2012; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123991/
  49. Hajiaghamohammadi, Ali Akbar, et al. “To Evaluate of the Effect of Adding Licorice to the Standard Treatment Regimen of Helicobacter Pylori.” The Brazilian Journal of Infectious Diseases, vol. 20, no. 6, Nov. 2016, pp. 534–538, 10.1016/j.bjid.2016.07.015; https://pubmed.ncbi.nlm.nih.gov/27614124/
  50. Nugroho, Agung Endro, et al. “Gastroprotective Effect of Combination of Hot Water Extracts of Licorice (Glycyrrhiza Glabra), Pulasari Stem Bark (Alyxia Reinwardtii), and Sembung Leaf (Blumea Balsamifera) against Aspirin-Induced Gastric Ulcer Model Rats.” Journal of Evidence-Based Complementary & Alternative Medicine, vol. 21, no. 4, 8 July 2016, pp. NP77–NP84, 10.1177/2156587216637469; https://pubmed.ncbi.nlm.nih.gov/26976086/
  51. Alammar, N., et al. “The Impact of Peppermint Oil on the Irritable Bowel Syndrome: A Meta-Analysis of the Pooled Clinical Data.” BMC Complementary and Alternative Medicine, vol. 19, no. 1, 17 Jan. 2019, 10.1186/s12906-018-2409-0; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337770/
  52. National Institutes of Health; National Center for Complementary and Integrative Health; “Peppermint Oil”; Last Updated October 2020; https://www.nccih.nih.gov/health/peppermint-oil
  53. Yago, Marc Anthony R. et al; “Gastric Re-Acidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria”; Molecular pharmaceutics 10.11 (2013): 4032–4037; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946491/
  54. Vakaliuk, P; “Significance of free hydrochloric acid and pepsin output in the study of gastric secretion”; Terapevticheskii arkhiv; 1970 Jul; 42(7):47-8; https://www.ncbi.nlm.nih.gov/pubmed/4921497
  55. Wang, D. Q; “Therapeutic uses of animal biles in traditional Chinese medicine: An ethnopharmacological, biophysical chemical and medicinal review”; World Journal of Gastroenterology, 20(29), 9952; 2014; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123376/
  56. Buford, T, et al; “Protease supplementation improves muscle function after eccentric exercise”; Medicine and Science in and Sports Exercise; 2009 Oct;41(10):1908-14; https://www.ncbi.nlm.nih.gov/pubmed/19727022
  57. Miller, P, et al; “The effects of protease supplementation on skeletal muscle function and DOMS following downhill running”; Journal of Sports Sciences; 2004 Apr;22(4):365-72; https://www.ncbi.nlm.nih.gov/pubmed/15161110
  58. Grabovac, V, et al; “Improvement of the intestinal membrane permeability of low molecular weight heparin by complexation with stem bromelain”; International Journal of Pharmaceutics; 2006 Dec 1; 326(1-2):153-9; http://www.ncbi.nlm.nih.gov/pubmed/16950580
  59. Guggi, D; “Improved paracellular uptake by the combination of different types of permeation enhancers”; International Journal of Pharmaceutics; 2005 Jan 6; 288(1):141-50; https://www.ncbi.nlm.nih.gov/pubmed/15607266
  60. Walker, A., Bundy, R., Hicks, S., & Middleton, R; “Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults”; Phytomedicine, 9(8), 681-686; 2002; https://www.ncbi.nlm.nih.gov/pubmed/12587686
  61. Braum, J., Schneider, B., & Beuth, H; “Therapeutic Use, Efficiency And Safety Of The Proteolytic Pineapple Enzyme Bromelain-POS In Children With Acute Sinusitis In Germany”; In Vivo; 2005; https://www.ncbi.nlm.nih.gov/pubmed/15796206
  62. Layer, P., and J. Keller. “Pancreatic Enzymes: Secretion and Luminal Nutrient Digestion in Health and Disease.” Journal of Clinical Gastroenterology, vol. 28, no. 1, 1 Jan. 1999, pp. 3–10, 10.1097/00004836-199901000-00002; https://pubmed.ncbi.nlm.nih.gov/9916657/
  63. Chakravarthy, P., & Acharya, S; “Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts”; Journal of Young Pharmacists, 4(4), 245-249; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573376/
  64. Burrows, David L., Andrea Nicolaides, Peter J. Rice, Michelle Dufforc, David A. Johnson, and Kenneth E. Ferslew; “Papain: A Novel Urine Adulterant*.” Journal of Analytical Toxicology 29, no. 5 (2005): 275-95; https://www.ncbi.nlm.nih.gov/pubmed/16105251
  65. Dwivedi, Amit J., et al. Digestive Diseases and Sciences, vol. 46, no. 5, 2001, pp. 1013–1015, 10.1023/a:1010701809950; https://pubmed.ncbi.nlm.nih.gov/11341642/
  66. Mandel, Abigail L., and Paul A. S. Breslin; “High Endogenous Salivary Amylase Activity Is Associated with Improved Glycemic Homeostasis Following Starch Ingestion in Adults”; The Journal of Nutrition 142.5 (2012): 853–858; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327743/
  67. Casas-Godoy, Leticia, et al. “Lipases: An Overview.” Lipases and Phospholipases, 2012, pp. 3–30, 10.1007/978-1-61779-600-5_1; https://pubmed.ncbi.nlm.nih.gov/22426709/
  68. Deng, Yanyong, et al. “Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.” Nutrients, vol. 7, no. 9, 18 Sept. 2015, pp. 8020–8035, 10.3390/nu7095380; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586575/
  69. Salem, Maryem Ben, et al. “Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits.” Plant Foods for Human Nutrition, vol. 70, no. 4, 27 Aug. 2015, pp. 441–453, 10.1007/s11130-015-0503-8; https://pubmed.ncbi.nlm.nih.gov/26310198/

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