Ghost Focus: Christian Guzman’s Stim-Free Nootropic

It’s collab season at Ghost, and they industry-leading brand is kicking it off with not just one, but three Christian Guzman fronted supplements:

Ghost Focus

Christian Guzman is here to boost your focus, and he’s doing it with a lot of high-quality choline!

Need a great nootropic… without the stims?!

As one of the busiest “athletepreneurs” in the business, Christian loves his nootropics. That’s why his fourth installment of Legend linked above had double doses of the three main focus ingredients, along with more energy than Ghost has ever used.

But what to take when you’re looking for that focus and want to keep it stim-free or just drink it alongside an energy drink or coffee?

The answer is Ghost Focus, with Christian Guzman’s legendary Lemon flavor.

This article digs into the ingredients of this new Ghost supplement, and is the second installment of our 2021 Christian Guzman Ghost collab series. As always, sign up for PricePlow’s Ghost news alerts, since there’s always something new around the corner:

Ghost Focus Stim-Free – Deals and Price Drop Alerts

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Ghost Focus Stim-Free Ingredients

Ghost Focus’ formula is quite similar to a lighter, stimulant-free version of Ghost Gamer, without the gaming-specific ingredients.

The label has both one and two scoop breakdowns — our listings are based upon two scoops. We’ll also focus on the cognitive effects of these ingredients, although most of them are multifaceted:

  • Acetyl-L-Carnitine HCl – 2000mg

    Ghost Focus Stim-Free Ingredients

    Stay focused without the stims, just like CG!

    Also known as ALCAR, Acetyl L-Carnitine is the form of supplemental L-carnitine that can cross the blood-brain barrier, which is why we prefer to see it in nootropic supplements.[1]

    Rewinding a touch, we often see various forms of carnitine in fat burners (Ghost Burn has two forms, half of it being ALCAR), since it helps with fatty acid transport to the mitochondria,[2] the cell’s “powerhouses”. Even without thinking about weight loss, this is still very positive, since we need to transport lipids in our brain as well. We always emphasize that carnitine’s best results come in those who are deficient – vegans, vegetarians, elderly, and exhausted athletes.[3,4]

    Getting back to our nootropic purposes, research has shown that ALCAR supplementation exhibits neuroprotective, neurotrophic, and antidepressant effects.[5] Additional studies have been published reporting a reduction in cognitive decline and an enhancement in brain synaptic response and overall learning capabilities.[6,7]

    ALCAR’s synergy with choline

    When talking about weight loss, we often cite several studies that show improved synergy with choline through increased carnitine retention,[8-11] and choline is a nutrient that’s dosed extremely well (covered later). That research still stands, but there’s additional synergy worth noting on a simple chemistry level:

    ALCAR Choline Acetylcholine Synthesis

    More synergy! If you’re low on acetyl groups, your choline may not get to the acetylcholine that you want. ALCAR (Acetyl L-Carnitine) listed above helps with that bottleneck.

    In the choline sections below, we’ll discuss acetylcholine, our “learning neurotransmitter” that’s released by the nervous system for inter-cell communication. In order to produce more, we need both portions of it – the choline and the acetyl groups. ALCAR provides those acetyl groups, and does so in a way that crosses the blood-brain-barrier discussed above.[1]

    With plenty of choline alongside, we’re set to have far fewer bottlenecks in generating this neurotransmitter, which will be great for anyone trying to avoid nasty brain fog.

    So there are two reasons why the choline + ALCAR combination is a slam dunk in a powdered nootropic.

  • L-Tyrosine (Vegan Fermented) – 1500mg

    Ghost Focus Christian Guzman

    Get it done

    L-Tyrosine is no stranger to nootropic formulas either. This non-essential amino acid is used for various purposes, but the two we’re zeroing in on today is neurotransmitter production and sleep deprivation support.

    Tyrosine is a chemical precursor to several important catecholamine neurotransmitters, including dopamine, epinephrine, and norepinephrine — all used to signal cellular communication and fire things up. Dopamine increases focus, cognition, motor function, and motivation.[12,13] Epinephrine (adrenaline) and norepinephrine (noradrenaline) activate our flight-or-fight response, boosting lipolysis and heart rate when we need them.[14,15]

    Sleep deprivation support from tyrosine

    Exhausted social media stars who run businesses like Christian Guzman are no stranger to lack of sleep. While we never recommend poor sleep hygiene, it does happen, and is important to understand how to best perform in its wake.

    Over the years, we’ve learned that there’s an incredible string of research showing that L-Tyrosine significantly boosts performance in sleep deprived individuals.[16,17] This has been performed over a half-dozen times, with research looking at tyrosine’s effects when exposed to low-sleep, stressful situations, and they’ve all shown success![16]

    Ghost legend Christian Guzman V4

    The fourth installment of the legendary Christian Guzman limited edition series of Ghost Legend is here, and it looks incredible – especially if you don’t want beta alanine or rauwolfia!

    There’s even enough data to have a systematic review on the matter, and one that was performed on members of the military states the following: “Nonetheless, we suggest that tyrosine or caffeine could be used in healthy young adults in a military context to enhance cognitive performance when personnel are sleep-deprived.”[17]

    Again – turn off your phone and get some sleep. But if you’re having a rough day after a rough night, consider some Ghost Focus with that L-Tyrosine included. The 1500mg dosage, by the way, is above average – we’re usually happy to get one gram.

  • Taurine – 1000mg

    Another ingredient with several uses, we often talk about taurine because of its incredible endurance enhancement, which has been shown by several studies in a meta-analysis, confirming that it works after just one use.[18] However, its benefits span the entire body, and that includes neuroprotection.

    Ghost Chips Ahoy Christian Guzman

    But can it top Chips Ahoy?!

    Taurine is an organic acid that works as an osmolyte, modulating water transfer and calcium concentrations throughout the body. It’s one of the most abundant amino acids in the brain, muscle, retina, and various organs, serving several roles in the central nervous system.[19,20]

    Despite taurine being a “conditional amino acid”, since our bodies can produce it but benefit from more, a great deal of information can be learned from a published review titled “Taurine: A ‘very essential’ amino acid”,[19] which shows the author’s insistence that it’s actually extremely essential to get enough of.

    The issue is that insufficient levels are linked to several health consequences, including neuron damage, development abnormalities, renal dysfunction, and cardiomyopathy.[19] It’s also critical for eye health, since it’s crucial for photoreceptor development.

    Taurine Benefits

    Taurine’s Benefits (endurance-wise) can be seen after a single use![18]

    Researchers are humble enough to admit that we don’t fully understand all of its mechanisms of action,[19] but we’re learning that one of its many cognitive improvements comes from the restoration of GABA receptors and taurine transporters.[20] This leads to reduced oxidative stress and neuroinflammation along with stimulated mitochondrial biogenesis and synaptic function.[20]

    In addition, research has shown taurine to be an important component in neurotransmission, and inadequate amounts (or inadequate intake) can lead to very poor memory and learning capabilities.[21]

    In general, this “conditionally essential amino acid” seems more and more “essential” with each passing year, especially given the poor quality of our food and agriculture these days.

  • Choline Blend (1100mg): Alpha-GPC (Alpha-Glyceryl Phosphoryl Choline 50%) – 600mg and Cognizin Citicoline – 500mg

    Now it’s back to the choline ingredients we referenced in the carnitine section – Ghost included two high-quality forms in Focus, making a blend that we absolutely love.

    The basics behind choline supplementation

    Ghost Gamer Sour Patch Kids Blue Raspberry

    Want focus with just a bit of stim? Then check out Ghost Gamer!

    In general, choline is a critical nutrient in the class of B-vitamins that helps maintain cell membrane structure and integrity.[22] And for our cognitive needs, it’s also the precursor to acetylcholine, which we always call “the learning neurotransmitter”, as it’s found in high concentrations in neuromuscular junctions, is of critical importance to the brain’s synapses, and is highly involved in cell-to-cell communication.[23]

    With more acetylcholine, we get improved memory, learning, attention, alertness, and even better balance and coordination.[24,25] When discussing pre workout supplements, we often talk about the “mind-muscle” connection it provides.

    On the opposite side of the coin, there are serious health issues that can arise when there’s a choline deficiency, ranging from general brain fog all the way to fatty liver disease and damage to organs and muscle.[26]

    So there’s no question choline is insanely important. Question for supplement formulators is, what type do you include?

    Christian Guzman’s answer? Both.

    • Alpha-GPC: Highly bioavailable, crossing the blood brain barrier

      Alpha-GPC is the first form, with a clinical dose of 600 mg provided in two scoops of Ghost Focus. This super-bioavailable form of supplemental choline is also known as alpha-glycerylphosphorylcholine and is quickly absorbed. But more importantly, Alpha-GPC is able to cross the blood brain barrier,[27] making it a fantastic partner with the acetyl L-carnitine listed above, as it can help your brain synthesize more acetylcholine.

      Acetylcholine

      Improved acetylcholine utilization provides for an ‘anti-blurring’ effect so that new and old memories do not get confused

      Beyond this ability, we’ve also seen some incredibly research in terms of power and performance at this dose,[28-31] and have already touched on the weight loss synergy with carnitine above.[8-11]

      This is already more choline than most supplements use. But Ghost and Guzman aren’t nearly done yet:

    • Citicoline: boost dopamine and norepinephrine!

      To top off choline stores even more, we have citicoline, scientifically known as Cytidine 5′-Diphosphocholine and CDP-Choline. This is a phenomenal feel-good choline source because citicoline can boost norepinephrine and dopamine levels, and has been shown to boost dopamine receptor density too![32]

      We’ve gone on the record countless times discussing how much we enjoy choline blends. There are many ways to do it, and this is likely the most expensive, but it’s also probably the hardest-hitting.

  • Aquamin (trace minerals derived from Red Marine Algae) – 500mg

    There may not be any direct evidence for cognition support here, but there are still benefits worth discussing. Aquamin is a naturally-sourced marine-based mineral complex that’s derived from red algae (Lithothamnion spp) – it’s a great source of calcium.[33]

    Ghost Energy Citrus

    Alternatively… stack it with Ghost Energy!

    Research has shown that Aquamin helps with bone and joint support,[33,34] so that’s generally the primary benefit. We’re supporters of the trace minerals inside, as we’re trying to alleviate any mineral deficiencies without adding a massive amount of added ingredients.

  • Raw Coconut (Cocos nucifera) Water Powder – 500mg

    On top of supporting flavor, coconut water powder can help enhance hydration status, which is critical to all aspects of health, not just the brain’s.

    Multiple studies have linked impaired cognition, mental fatigue, and brain fog with simple dehydration![35,36] Along with Aquamin, coconut water powder may help you keep your hydration status, including important electrolytes along with the water.

    One research study found that coconut water was just as good as a carbohydrate-electrolyte drink in terms of whole-body rehydration.[37] This is why we see it in several supplements, ranging from Ghost Amino (taken during workouts) to Ghost Gamer.

  • AstraGin (Astragalus membranaceus and Panax notoginseng) Root Extracts – 50mg

    The industry’s favorite absorption-enhancing ingredient, AstraGin is a unique blend of plant extracts made by NuLiv Science. In our article titled Astragalosides and Ginsenosides: Differentiating NuLiv Science’s Ingredients, we recently dug deep into the science behind the benefits of its constituents.

    The long story short is that AstraGin is best known for its ability to increase the absorption of other ingredients by the activation of transporters in your small intestines.[38] This has been tested on several different amino acids often taken by athletes. In addition, AstraGin may improve gut health by reducing inflammation and promoting integrity of the GI lining.[38]

  • Added Vitamins

    Ghost Focus Stim-Free has a blend of added vitamins that include Vitamin C, Vitamin E, Niacin, Vitamin B6, and Vitamin B12.

    Of these, the two we want to point out are Pyridoxal-5-Phosphate (P5P) as vitamin B6 and methylcobalamin as Vitamin B12, which we like far more than the pyridoxine and cyanocobalamin (respectively) that’s used in cheaper formulas. Reasons below:

    • P5P over Pyridoxine

      Vitamin B6 Pyridoxine Cell Death

      What’s the deal with Pyridoxine causing all of that cell death?! It’s probably best not to supplement it. In this chart, higher is WORSE![39]

      Pyridoxal-5′-phosphate (PLP or P5P) is the body’s preferred form of B6, and is easily dephosphorylated and absorbed.[40] Consider pyridoxal to be the animal form, whereas pyridoxine is the plant-based form. More often than not, the form closer to what’s found in animal tissue is the form that’s more readily bioavailable, and that’s the case here.

      Even more important is the fact that research has found too much supplemental B6 in the form of pyridoxine to potentially cause severe sensory neuropathy![41] This has not been found in food-derived or animal-sourced B6 that’s higher in pyridoxal. What’s happening is actually quite ironic: a 2017 study found that supplemental vitamin B6 from pyridoxine inhibits B6-dependent enzymes in the body, and competitively limits P5P absorption![39]

    • Methylcobalamin vs. Cyanocobalamin

      Meanwhile, Ghost has opted for methylcobalamin, the active form of vitamin B12, as opposed to the cheaper cyanocobalamin, which is inactive. This is our litmus test for whether a supplement company really cares, because it’s more expensive and not a ton of people look this closely at the label. Reason being, in order to “activate” the cheaper cyanocobalamin form, the body must remove cyanide from it in order to convert it to methylcobalamin![42]

      Ghost Legend Lemon

      Legend

      In addition, to carry out the above process with cyanocobalamin, the body must provide a valuable methyl group,[43] adding another tax to your body! In general, researchers have concluded that it’s less effective than methylcobalamin,[44,45] which isn’t surprising.

      So why do we still see cyanocobalamin instead of methylcobalamin? You can probably guess why – but Christian Guzman and Team Ghost aren’t having it.

Ghost Focus Flavors

At launch, Christian Guzman’s Lemon flavor is the only flavor, but in case others come out in the future, see the list below:

    Watch the Team Talk about Focus

    The team first introduces Focus in season 7 episode 19 of their Building the Brand YouTube Series titled “Five Legendary Years”:

    Subscribe to PricePlow on YouTube!

    They also go further in the episode titled “CG SZN FOUR” (S7:E20):

    Subscribe to PricePlow on YouTube!

    Stim-Free Focus: How Christian Guzman Keeps Going

    Ghost Focus

    These tubs are very unlike Ghost, but they’re also very slick.

    You can’t drink caffeine all the time. And even if you could, sometimes you want a coffee, fat burner, or energy drink instead of Ghost Gamer or that insanely well-formulated Ghost Legend V4 Christian Guzman collab.

    When you need a blast of choline, carnitine, tyrosine, and taurine… but want to keep the stimulants away, this is where to go. Fight through the brain fog of dieting or sleep deprivation and stay true to your path — just like CG has stayed true to his — with Ghost’s Stim-Free Focus.

    We sound like a broken record at this point, but anytime we see well-dosed choline blends, we get excited, because we know it’s going to feel good for us. We’re confident it will for you too, and we’re happy to see Ghost (and Guzman) paying attention to the details with the quality forms of B-Vitamins and natural mineral sources.

    A stim break doesn’t need to mean a total focus break. Focus should help you keep the lights (and the lemon) on even without the caffeine.

    Ghost Focus Stim-Free – Deals and Price Drop Alerts

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    Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

    Posts are sponsored in part by the retailers and/or brands listed on this page.

    About the Author: Mike Roberto

    Mike Roberto

    Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

    Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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    References

    1. Parnetti, L, et al; “Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type”; Eur J Clin Pharmacol. 1992; 42(1):89-93; https://pubmed.ncbi.nlm.nih.gov/1541322
    2. Karlic, Heidrun, and Alfred Lohninger. “Supplementation of L-Carnitine in Athletes: Does It Make Sense?” Nutrition, vol. 20, no. 7-8, July 2004, pp. 709–715, 10.1016/j.nut.2004.04.003; https://pubmed.ncbi.nlm.nih.gov/15212755/
    3. Lombard, K A, et al. “Carnitine Status of Lactoovovegetarians and Strict Vegetarian Adults and Children.” The American Journal of Clinical Nutrition, vol. 50, no. 2, 1 Aug. 1989, pp. 301–306, 10.1093/ajcn/50.2.301; https://pubmed.ncbi.nlm.nih.gov/2756917/
    4. Novakova, Katerina, et al. “Effect of L-Carnitine Supplementation on the Body Carnitine Pool, Skeletal Muscle Energy Metabolism and Physical Performance in Male Vegetarians.” European Journal of Nutrition, vol. 55, no. 1, 23 Jan. 2015, pp. 207–217, 10.1007/s00394-015-0838-9; https://pubmed.ncbi.nlm.nih.gov/25612929/
    5. Ando, S. et al. Oct. 2001. “Enhancement of Learning Capacity and Cholinergic Synaptic Function by Carnitine in Aging Rats.” Journal of Neuroscience Research vol. 66,2. 266-71. https://pubmed.ncbi.nlm.nih.gov/11592123/
    6. Traina, G. June 2016. “The Neurobiology of Acetyl-L-Carnitine.” Frontiers in Bioscience vol.1, 21. 1314-29. https://pubmed.ncbi.nlm.nih.gov/27100509
    7. Passeri, M., et al. 1990. “Acetyl-L-Carnitine in the Treatment of Mildly Demented Elderly Patients.” International Journal of Clinical Pharmacology Research vol. 10,1-2.75-9. https://pubmed.ncbi.nlm.nih.gov/2201659
    8. Elsawy G, Abdelrahman O, Hamza A. Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes. Journal of Human Kinetics. 2014;40:77-82. doi:10.2478/hukin-2014-0009. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096089/
    9. Dodson WL, Sachan DS. Choline supplementation reduces urinary carnitine excretion in humans. Am J Clin Nutr. 1996;63(6):904-910. https://www.ncbi.nlm.nih.gov/pubmed/8644685
    10. Hongu N, Sachan DS. Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. J Nutr. 2003;133(1):84-89. http://jn.nutrition.org/content/133/1/84.long
    11. Daily JW 3rd, Sachan DS. Choline supplementation alters carnitine homeostasis in humans and guinea pigs. J Nutr. 1995;125(7):1938-1944. https://www.ncbi.nlm.nih.gov/pubmed/7616311
    12. Attipoe, Selasi, et al. “Tyrosine for Mitigating Stress and Enhancing Performance in Healthy Adult Humans, a Rapid Evidence Assessment of the Literature.” Military Medicine, vol. 180, no. 7, July 2015, pp. 754–765, 10.7205/milmed-d-14-00594. https://academic.oup.com/milmed/article/180/7/754/4160625#101253256
    13. Mishra, Akanksha, et al. “Physiological and Functional Basis of Dopamine Receptors and Their Role in Neurogenesis: Possible Implication for Parkinson’s Disease.” Journal of Experimental Neuroscience, vol. 12, Jan. 2018, p. 117906951877982, 10.1177/1179069518779829. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985548/
    14. Rajeev Dalal, and Dejan Grujic. “Epinephrine.” Nih.gov, StatPearls Publishing, 2 Apr. 2019. https://www.ncbi.nlm.nih.gov/books/NBK482160/
    15. Smith, Matthew D, and Christopher V Maani. “Norepinephrine.” Nih.gov, StatPearls Publishing, 23 July 2019. https://www.ncbi.nlm.nih.gov/books/NBK537259/
    16. Attipoe, Selasi, et al. “Tyrosine for Mitigating Stress and Enhancing Performance in Healthy Adult Humans, a Rapid Evidence Assessment of the Literature.” Military Medicine, vol. 180, no. 7, July 2015, pp. 754–765, 10.7205/milmed-d-14-00594; https://academic.oup.com/milmed/article/180/7/754/4160625
    17. Pomeroy, Diane E., et al. “A Systematic Review of the Effect of Dietary Supplements on Cognitive Performance in Healthy Young Adults and Military Personnel.” Nutrients, vol. 12, no. 2, 20 Feb. 2020, p. 545, 10.3390/nu12020545; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071459/
    18. Waldron, Mark, et al. “The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis.” Sports Medicine, vol. 48, no. 5, 15 Mar. 2018, pp. 1247–1253, 10.1007/s40279-018-0896-2. https://pubmed.ncbi.nlm.nih.gov/29546641/
    19. Ripps, Harris, and Wen Shen. “Review: Taurine: A ‘Very Essential’ Amino Acid.” Molecular Vision, vol. 18, 12 Nov. 2012, pp. 2673–2686. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501277/
    20. Chen, C., et al. Aug. 2019. “Roles of Taurine in Cognitive Function of Physiology, Pathologies and Toxication.” Life Sciences vol. 15,231. https://pubmed.ncbi.nlm.nih.gov/31220527/
    21. Roysommuti, S., Wyss, JM. 2015. “Chapter 22 – The Effects of Taurine Exposure on the Brain and Neurological Disorders, from: Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease.” Prevention and Therapy. 207-213. https://www.sciencedirect.com/science/article/pii/B9780124114623000229
    22. Sanders LM, Zeisel SH; “Choline: Dietary Requirements and Role in Brain Development;” Nutrition today; 2007;42(4):181-186; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518394/
    23. Purves D, Augustine GJ, Fitzpatrick D, et al.; “Neuroscience;” 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Acetylcholine. https://www.ncbi.nlm.nih.gov/books/NBK11143/
    24. Hasselmo ME; “The role of acetylcholine in learning and memory;”Curr Opin Neurobiol. 2006;16(6):710–715; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659740/
    25. Jones BE; “From waking to sleeping: neuronal and chemical substrates”. Trends Pharmacol. Sci.; 2005; 26 (11): 578–86; https://www.ncbi.nlm.nih.gov/pubmed/16183137
    26. Ueland, P. M.; “Choline and betaine in health and disease;” Journal of Inherited Metabolic Disease; 2010; 34(1), 3–15; https://onlinelibrary.wiley.com/doi/abs/10.1007/s10545-010-9088-4
    27. Marcus L, et al; “Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance;” J Int Soc Sports Nutr; 2017;14:39; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629791/
    28. Bellar D, LeBlanc NR, Campbell B; “The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength”; J Int Soc Sports Nutr. 2015; 12(1):42; http://www.jissn.com/content/12/1/42
    29. Ziegenfuss T, Landis J, Hofheins J. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Journal of the International Society of Sports Nutrition. 2008;5(Suppl 1):P15. doi:10.1186/1550-2783-5-S1-P15; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313098/
    30. De Jesus Moreno Moreno M; Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial . Clin Ther. (2003); https://linkinghub.elsevier.com/retrieve/pii/S0149291803900233
    31. Parnetti L, Amenta F, Gallai V; Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: an analysis of published clinical data . Mech Ageing Dev. (2001); https://linkinghub.elsevier.com/retrieve/pii/S0047637401003128
    32. Secades, JJ; “Citicoline: pharmacological and clinical review, 2016 update;” Rev Neurol; 2017; https://www.researchgate.net/profile/Julio_Secades/publication/317167480_Citicoline_pharmacological_and_clinical_review_2016_update/links/59280785a6fdcc444353790e/Citicoline-pharmacological-and-clinical-review-2016-update.pdf
    33. Frestedt JL, Kuskowski MA, Zenk JL; “A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: a randomised, placebo controlled pilot study”; Nutr J. 2009; 8:7; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642861/
    34. Brennan O. et al; “Incorporation of the natural marine multi-mineral dietary supplement Aquamin enhances osteogenesis and improves the mechanical properties of a collagen-based bone graft substitute”; J Mech Behav Biomed Mater. 2015 Jul; 47:114-123; https://www.ncbi.nlm.nih.gov/pubmed/25884141
    35. Wilson, M., Morley, J. “Impaired cognitive function and mental performance in mild dehydration”; Eur J Clin Nutr 57, S24–S29 (2003); https://www.nature.com/articles/1601898#article-info
    36. Pross, N. “Effects of Dehydration on Brain Functioning: A Life-Span Perspective”; Ann Nutr Metab 2017; 70(suppl 1):30-36; https://www.karger.com/Article/Fulltext/463060
    37. Saat, Mohamed, et al; “Rehydration after Exercise with Fresh Young Coconut Water, Carbohydrate-Electrolyte Beverage and Plain Water”; Journal of Physiological Anthropology and Applied Human Science; U.S. National Library of Medicine; Mar. 2002; https://www.ncbi.nlm.nih.gov/pubmed/12056182
    38. NuLiv Science; AstraGin Product Dossier; https://docdro.id/rA01t9O
    39. Vrolijk, Misha F, et al; “The Vitamin B6 Paradox: Supplementation with High Concentrations of Pyridoxine Leads to Decreased Vitamin B6 Function.”; Toxicology in Vitro : an International Journal Published in Association with BIBRA; U.S. National Library of Medicine; Oct. 2017; https://www.ncbi.nlm.nih.gov/pubmed/28716455
    40. McCormick D. Vitamin B6. In: Bowman B, Russell R, eds. Present Knowledge in Nutrition. 9th ed. Washington, DC: International Life Sciences Institute; 2006; https://www.scirp.org/(S(i43dyn45teexjx455qlt3d2q))/reference/ReferencesPapers.aspx?ReferenceID=559786
    41. Schaumburg, H, et al; “Sensory Neuropathy from Pyridoxine Abuse. A New Megavitamin Syndrome.”; The New England Journal of Medicine; U.S. National Library of Medicine; 25 Aug. 1983; https://www.ncbi.nlm.nih.gov/pubmed/6308447
    42. Herbert, V; “Vitamin B-12: Plant Sources, Requirements, and Assay”; Am J Clin Nutr September 1988; vol. 48 no. 3 852-858; http://ajcn.nutrition.org/content/48/3/852.long
    43. Bottiglieri, T; “Folate, vitamin B₁₂, and S-adenosylmethionine”; Psychiatr Clin North Am. 2013 Mar;36(1):1-13; http://www.ncbi.nlm.nih.gov/pubmed/23538072
    44. Obeid, R., Fedosov, S. N. and Nexo, E. (2015), “Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency”; Mol. Nutr. Food Res., 59: 1364–1372; http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201500019/full
    45. Adams, J; “Absorption of cyanocobalamin, coenzyme B 12 , methylcobalamin, and hydroxocobalamin at different dose levels”; Scand J Gastroenterol. 1971;6(3):249-52; http://www.ncbi.nlm.nih.gov/pubmed/5560708

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