Tim Muriello is one of the most widely recognized faces in the supplement, gaining popularity for the thousands of videos he put together while working with I’llPumpYouUp. However, Tim has parted ways with the e-commerce store and ventured out on his own to build a brand and establish himself as a true force in the industry.
Spazmatic is the first product released by Tim’s new company, and it’s a rather well-dosed pre workout compared to what we’ve seen from other YouTube personalities recently.
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Spazmatic is a fully loaded pre workout that brings energy, focus, and pumps. The DMHA is a bit on the light side compared to other pre workouts we’ve tried, but all in all, if you like high caffeine, pump heavy pre workouts, this one will appeal to you!
Total SPAZ Energy Squad
Spazmatic isn’t messing around with raw energy. It packs a total of 400mg caffeine / scoop in the form of 300mg caffeine anhydrous + 100mg caffeine from Green Tea.
Anhydrous provides the immediate slap you in the face energy to get you moving, while the 100mg of caffeine from green tea provides a more sustained, smoother energy release during your workout.
Slow or fast, you’re still getting hit with 400mg caffeine in total, so if you’re stim-sensitive, we’d suggest you start with ⅓-½ scoop your first few times running Spazmatic.
Also known as DMHA, Kigelia Africana extract, and 2-amino-6-methylheptane, 2-Aminoisoheptane is the most popular next-gen stim these days that used in lieu of DMAA. Similar to DMAA, DMHA is an aliphatic amine that enhances dopamine and noradrenaline (norepinephrine) production in the body.[2,3] This gives the user a significant increase in energy, alertness and mood.
The dose here is OK, but we’ve seen higher amounts used in several other pre workouts, so if you’re new to DMHA, this might be a good way to test out the stimulant if you’re still relatively new to it.
Normally, we’ve been seeing DMHA paired with different forms of PEA, such as eria jarensis extract. This is not the case in Spazmatic — so if you don’t like the quick up-and-down PEA strike, then Spazmatic may be the one for you!
Higenamine HCl (30mg)
Higenamine, a.k.a. norcoclaurine, is a beta-2 receptor agonist (similar to Synephrine) that ramps up production of noradrenaline, which stimulates the “fight or flight” response furthering your motivation, focus, and drive during training.
This stimulant also cultivates fatty acids from stored body fat reserves to be used for energy during training, thus sparing your glycogen stores to be used for the really intense moments of training.
Hordenine HCl (30mg)
Much like the previous ingredient, Hordenine is another beta-receptor agonist that stimulates lipolysis in the body. More importantly though, hordenine functions as an MAO inhibitor and noradrenaline (norepinephrine) reuptake inhibitor.[7,8] This means Hordenine prevents noradrenaline from being taken up in the body, prolonging its effects, resulting in significantly greater focus, alertness, and attention.
Eliminate Distractions Focus Duo
To kick off the focus portion of Spazmatic, Tim has included the more effective form of Tyrosine in L-Tyrosine. We’ve settled the debate of L-Tyrosine vs N-Acetyl L-Tyrosine before in our mega post: L-Tyrosine vs. N-Acetyl L-Tyrosine: A Tale of Two Tyrosines, so you can head over there if you want the full story.
Suffice it to say we’re glad to see L-Tyrosine included at a very nice dose, which should pay dividends for you at improving focus, mood, and reducing stress.[9,10]
Huperzine 1% (200mcg)
The other half of Spazmatic’s focus-boosting duo is the acetylcholine-sustaining nootropic, huperzine A. Also known as Toothed Clubmoss, Huperzine inhibits acetylcholinesterase, the enzyme which degrades acetylcholine, which accomplished the effect of indirectly boosting acetylcholine levels.
This translates in greater focus during your workouts and it also offers you some neuroprotective benefits as well.[11,12,13]
Clutch Spazoid Pump Team
Now, the part most of you have been waiting for…the pump portion of Spazmatic. Tim goes with one of the premier N.O. boosters in the market in L-Citrulline. It’s significantly more effective than L-Arginine, and the dose here is top notch.
4.5g worth of pure L-Cit will set you up for some major pumps and vascularity during your training sessions. Plus, you’ll also get some endurance and performance benefits from the ingredient as well — allowing for more productive training sessions.
Normally, we’ve been seeing these pre workouts top out at 4g of L-Citrulline — but like any good fitness celebrity, Tim had to one-up his competition with even more!
Norvaline is included to sustain the nitric oxide-elevating effects of Citrulline. We say that because Norvaline inhibits the enzyme the degrades arginine in the body, arginase. Doing so indirectly boosts nitric oxide levels by preserving and prolonging its effects in the body, translating to bigger, long-lasting pumps and vascularity.
Tim’s brand has just launched, so flavors are minimal at the moment for Spazmatic, as there is only one — Watermelon Taffy, which is truly a delicious flavor! We’ve been using it and enjoying it since our interview with Tim.
If the product catches on, as we expect it to, and really sell, we expect to see more flavors rolling out in the coming months.
And how can you not love this labeling, which is everything that personifies Tim!!
Don’t miss Mike’s interview with Tim!
After Spazmatic released, Mike and Tim did a Skype interview together, and it was a damn good time. Check it out as they talk about everything from this supplement to Tim’s career to travel and women!
Are you ready to go full SPAZ with Tim Muriello?!
Spazmatic is a solid offering from one of the most recognizable faces in the business. One that offers energy, focus, and pumps — provided you can handle the 400mg of caffeine. This is just what Tim’s fans were asking for, and he delivered.
We’re not sure when Tim is planning to release his other products, but if Spazmatic is any indication of what’s in store, we’ll need to keep our eye on him a bit closer.
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- Rasmussen, N., & Keizers, P; “History Full Circle: Novel sympathomimetics in supplements” Drug testing and analysis; 2015; Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/dta.1852/abstract
- Millan, M; “The role of monoamines in the actions of established and novel antidepressant agents: a critical review”; European Journal of Pharmacology; 500(1): 371-384; 2004. Retrieved from http://www.sciencedirect.com/science/article/pii/S0014299904007472
- Fleckenstein, A., Volz, T., Riddle, E., Gibb, J., & Hanson, G; “New Insights into Mechanism of Action of Amphetamines”; Annual review of Pharmacology and Toxicology; 47: 681-698; 2007. Retrieved from http://www.annualreviews.org/doi/abs/10.1146/annurev.pharmtox.47.120505.105140
- Wise, R., & Bozarth, M; “Brain Mechanism of Drug Reward and Euphoria”; Journal of Psychiatric Medicine, 3(4): 445-460; 1985. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/2893431
- Frank M, et al; Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse; Equine Vet J. (1990)
- Barwell C.; School of Pharmacy; “Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat;” 1989
- Nedergaard O.; British Journal of Pharmacology; “Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig;” November 1968
- Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
- Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
- Zhao, Q; Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; 2002
- Ved, H; Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.; Division of Biochemistry, Walter Reed Army Institute of Research; 1997
- Ma, T; Huperzine A promotes hippocampal neurogenesis in vitro and in vivo.; State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University; 2013
- Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007. http://www.ncbi.nlm.nih.gov/pubmed/17693747