A hard lifter’s dream! Juggernaut Nutrition Irate Extreme gets the job done and beyond – even for the biggest of lifters
That’s because today, we’re looking at their intense Irate Extreme pre workout, with an impressive label that is heavily stimulant based, but also doesn’t forget to add in the other pre workout necessities. This is the first product we’ve reviewed from Juggernaut Nutrition, and it most likely won’t be the last, because it’s a damn good one.
Before we break down this intense stimulant-driven panel, be sure to sign up for PricePlow’s coupon driven deals to make sure you’re getting the best prices, and sign up for Juggernaut Nutrition alerts to stay up to date with all that is happening with this rapidly-growing brand:
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Irate Ingredients
We love a good stimmed up supplement here at PricePlow, and with a label like this, Irate Extreme is sure to deliver. We’re getting a “moderate” 275mg caffeine here, from anhydrous and fast-acting citrate, but we say “moderate” in quotes because we’re also getting some PEA, DMHA, and just enough alpha yohimbine to make things exciting.
Mind and Focus Blend
Let’s get the energy and focus started:
N-Acetyl L-Tyrosine (500mg)
Two forms of caffeine, DMHA, PEA, ‘super synephrine’, and alpha-yo? And that’s not even getting into the pump formula?! Get ready to get wowed
L-Tyrosine is an organic amino acid, which is the body’s precursor to the catecholamines, which are energetic and mood boosting chemicals, including epinephrine, norepinephrine, and dopamine.[1] By increasing levels of these catecholamines, you get a focus and mood boost, but the effects can even go further. Tyrosine has been shown to minimize stress and anxiety interestingly enough.[2,3] While the N-Acetyl version was originally touted to be more bioavailable, the straight L-Tyrosine form was seen as the better form more recently.[4] Regardless, we always enjoy seeing some tyrosine to help with our focus.
Caffeine Anhydrous (200mg)
Perhaps the most well-known preworkout ingredient, we have our first stimulant as caffeine anhydrous. Caffeine is a central nervous system stimulant, which gives you a feeling of alertness and helps clear out the brain fog when you’re feeling tired.
In addition to helping you wake up, caffeine does have some clinical research behind it in terms of strength. At doses of 5-6mg per kg of body weight, we actually have clinical strength gains shown.[5,6] For reference, a 70kg (154lbs) individual would need a dose of 350-420mg of caffeine. While we happen to be a bit short of that here, we do have another caffeine source up next to help close the gap between that.
Another interesting note about caffeine is it’s lipolytic effects, allowing you to burn more fat by oxidizing fatty acids.[7,8,9]
Caffeine is a substance that your body builds a tolerance to rather quickly. To minimize these effects, try cycling off from time to time to prevent becoming too tolerant to caffeine’s effects.
Caffeine Citrate (150mg)
On top of caffeine anhydrous, we also have caffeine as caffeine citrate, which is caffeine bound to a citrate molecule. Anecdotally, we find this caffeine to hit a bit quicker than the usual anhydrous version.
Due to the nature of this ingredient, only 50% of the actual mass is caffeine, meaning 75mg of caffeine is yielded. This brings our total caffeine amount up to 275mg. But if that isn’t enough for you, we have plenty of stims to go.
DMHA (2-amino-5-methylhexane) (150mg)
DMHA, also known as 2-aminoisoheptane, is the most hardcore stimulant legally available right now. DMHA belongs to a class of substances known as aliphatic amines.[10] These chemicals give a strong focus boost and intense euphoria by releasing catecholamines, similarly to tyrosine, while simultaneously slowing the reuptake of those same neurotransmitters. We have 150mg of this strong stimulant here, so expect some serious energy and focus coming from just this ingredient alone.
We’re left to believe that this is the 2-amino-5-methylheptane form of DMHA, which is also the stronger one. 150mg of this is no joke, especially when paired with the next two ingredients!
N-Phenethyl Dimethylamine (120mg)
Up next is a form of PEA, known as N-Phenethyl Dimethylamine. This ingredient is known for its mood boosting properties, as PEAs generally are.[11] The issue with straight PEA is that it’s usually broken down fairly quick by the MAO enzyme, but this form has some protection against that. Two alkyl groups are attached to the PEA section of this molecule, offering a resistance to being quickly broken down.
N-Phenethyldimethylamine is like a PEA molecule, but with an N,N’ Alkyl section that also prevents MAO from cleaving it… meaning a longer-lasting euphoric ‘buzz’ than regular PEA
This causes our euphoric sensations and some serious mood boosting to be prominent for much longer than usual. 120mg is an awesome dose, and especially with the DMHA, you can expect some serious mood boosting.
If you feel Irate kick in a bit shorter than the average pre workout, it’s because of this ingredient.
Isopropylnorsynephrine (10mg)
The void left by the exit of various PEA-backboned stimulants from the market allowed new ingredients to come to the forefront of the market. One of these is the ingredient isopropylnorsynephrine. Synephrine may look familiar to you from bitter orange extract, but this isopropyl version is substantially more potent.[12]
Isopropylnorsynephrine gets its effects from its ability as a lipolytic, which means it frees up fatty acids for the body to use as energy.[13] This is definitely one of the stronger stimulants out there, so be cautious starting with a full scoop with this product.
Rauwolscine (2mg)
Perhaps the most controversial ingredient over time at PricePlow, Rauwolscine, or also known as Alpha-Yohimbine. Alpha-Y, as it’s sometimes called, is an intense alkaloid that causes quite the impressive adrenaline releasing effect.[14] Similar to regular yohimbine, but with a different molecular orientation, it is a alpha-2 antagonist, which means it blocks this pathway. This may help in fat loss by helping the body remove fat and helping prevent fat storage in the future.[15]
Since this is a 90% dose, the actual Alpha-Y dose is slightly below 2mg (1.8mg), which should be tolerated by most. But, some people experience intense effects with this ingredient, such as anxiousness or cold sweats.
Speaking personally, we typically enjoy ~1.5mg as our preferred dose here, so we’ll often end up at just under a full scoop. As always with any hardcore pre workout, use half a scoop to assess dosage and slowly work your way up until you hit your peak! No reason to full scoop it right away – this product is strong.
Pump and Power
If you were worried that this was simply a stim bomb, you can rest assured that Juggernaut Nutrition also took some other things into account. We have some daily ergogenics as well as some pump enhancers thrown in here.
Citrulline Malate (5,000mg)
The staple pump ingredient that we love to see for nitric oxide production is good old fashioned citrulline malate. We have a 2:1 ratio here, giving us just over 3 grams of actual citrulline here, which is where we start to clinically see pump enhancing effects come into play.
Citrulline entered the market as an improvement over the amino acid arginine, due to the extremely low bioavailability of arginine. We quickly found out that arginine was nearly completely destroyed by the digestive tract when supplemented orally, giving us a minimal nitric oxide boost when using reasonable doses. Higher doses could have been used to remedy this issue, but the dose necessary would have been extremely large, and would cause gastrointestinal issues for many users. To remedy these issues, we now have citrulline.
Thankfully, citrulline avoids being broken down in the gastrointestinal tract, which allows it to enter the bloodstream, and get converted to arginine. These boosted arginine levels then boost nitric oxide production, giving us vasodilation, and therefore, bigger pumps.[16] This plays especially well with another ingredient we have coming up soon as well.
Citrulline also does more than just enhance your pumps, it also has a practical application as well. Citrulline can reduce your post-workout soreness, increase your overall training capacity, and help reduce fatigue.[17,18]
Beta Alanine (2,500)
Another common pre workout ingredient, beta alanine is the ingredient responsible for the tingly sensation that some users experience when using pre workout. This harmless tingling sensation can be bothersome at higher doses, but shouldn’t be unbearable here. Beta alanine works by bonding with the amino acid histidine, forming a substance known as carnosine. This carnosine acts as a lactic acid buffer in your muscle cells, which comes with a whole slew of benefits associated with it. Supplementing with beta alanine has been shown to increase work capacity, increase peak power output, reduce fatigue, and improve overall athletic performance.[19-22]
Beta alanine functions best during exercises lasting from 1-4 minutes, making it a sort of muscular endurance enhancer.[23,24] By allowing you to do more overall work, especially in high rep ranges, beta alanine supplementation can indirectly help with fat loss as well.[25]Beta Alanine Boosts Exercise Performance when taken 3.2g per day (but that was split amongst four separate doses)
The clinical study with beta alanine used 3.2g, which is 700mg more than we have here, but split doses throughout the day. What this means is that to reach the total dose used in those studies, in may be a good idea to get some other forms of beta alanine supplementation elsewhere during the day in addition to taking this preworkout.
Creatine HCl (1,500mg)
Creatine HCl is perhaps the most popular alternative form of creatine, and has been touted as superior due to its chemical properties. Creatine works by acting as a phosphate group donor to ADP. When we exercise, our bodies use ATP to contract our muscles. When the ATP is used, it becomes ADP and must be regenerated through our metabolic pathways.
All smiles with this pre! As a thank you for using Taylor’s picture, use her TAY15 coupon if buying direct!
What creatine does is give ADP a phosphate group, regenerating it into ATP, essentially acting as an energy bank for our muscles. While creatine monohydrate is certainly the most popular and research backed form, creatine HCl may have better solubility in water due to the inclusion of the hydrochloride group. Regardless, there isn’t much to back this up, and the doses needed of either form should be very similar.
Creatine HCl does have one other advantage though, which is that users tend to experience less bloating and GI distress as compared to using monohydrate, which has been known to be upsetting to some stomachs.
Unfortunately, we only have 1.5g here, which is about half of what we would like to see minimally for creatine doses daily, so you’ll still want to snag a bit more creatine elsewhere in the day… or just eat a ton of beef like we do and you’re good to go!
Agmatine Sulfate (500mg)
If citrulline is the offensive side of the nitric oxide battle, agmatine sulfate is the defensive side. Our bodies love homeostasis, so when we boost up our nitric oxide levels, our bodies want to bring them back down. To do so, we produce the enzyme known as arginase, which breaks down arginine in the bloodstream, something we simply do not want while we are trying to maintain max blood flow in the gym.[26,27]
This is where agmatine comes in. Agmatine acts as an inhibitor to the arginase, which lowers the amount of arginase available to break down the arginine in the bloodstream. This allows us to keep our nitric oxide levels boosted longer than usual. An ingredient like this plays especially well when combined with a nitric oxide promoter, like citrulline.
500mg is the minimal beginner dose we like to see for preworkouts, but it should make a nice addition to the pump section, which isn’t the main focus of this preworkout anyway.
Absorption
Get your ingredients in:
Black Pepper Extract (5mg)
Our last ingredient is black pepper extract, which enhances the bioavailability of the substances in a supplement, giving us the best absorption of the ingredients, making sure we utilize all of them as best as our body can.
The flavors
Below is a list of flavors, but you may need to head direct to JuggernautSupplements.com linked below if they’re not showing up in stock:
Brock tells us that they take their flavoring seriously, and with the one flavor we’ve tried (Braxton’s Sour Pals), we agree!
Final Thoughts
Juggernaut Nutrition has put together not only a respectable stim profile, but quite a hardcore one at that. With some exotic stimulants coupled with a two-pronged caffeine attack, Irate is certainly not to be messed with in the realm of hardcore preworkouts. As for flavors, you have some unique options that sound absolutely delicious, like Sour Pals and Rainbow Drops. We look forward to reviewing how this product goes, and whether the effects live up to the label.
Juggernaut Nutrition Irate Extreme - Deals and Price Drop Alerts
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Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.
Posts are sponsored in part by the retailers and/or brands listed on this page.
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