Let's Go! Brings a Liposomal BHB Gel to the Exogenous Ketone Category

Let's Go!

Let's Go! puts 4,000mg goBHB into a liposomal gel sachet -- a format the exogenous ketone category hasn't seen before. Caffeine-free, no mixing, and built for brain fuel when it counts most.

Let's Go! enters the exogenous ketone space with a format the category hasn't really seen before: a liposomal BHB gel in a single-serve sachet. Where most BHB products come as powders, capsules, or beverages, Let's Go! wraps 4000mg of goBHB in a phospholipid delivery system designed to improve how your body takes up ketones, with no shaker required, no caffeine, and none of the usual powder aftertaste.

That versatility is by design. Let's Go! is built for anyone running a high-demand life: athletes, professionals, as well as women navigating hormonal transitions who may find their brain's ability to efficiently use glucose as fuel diminishes over time. BHB offers an alternative fuel source the brain can use directly, and the emerging science around ketones and cognitive resilience is one of the reasons this ingredient has drawn serious research interest beyond sports nutrition.

If you're new to exogenous ketones, our BHB Supplements: The Ultimate Guide to Exogenous Ketones lays out why beta-hydroxybutyrate has become one of the more interesting ingredients in sports nutrition. We've also got a fresh round of BHB research we'll be covering soon, including some new studies with meaningful implications for athletes and anyone interested in metabolic performance. Stay tuned for that.

Let's get into Let's Go, starting with BHB, the new research, and then explore how phosphatidylcholine-based liposomes serve a dual purpose in this wildly unique and usefulp product:

Let's Go! Ingredients

Each 15mL sachet keeps the panel tight: two active ingredients, a modest electrolyte load, and a clean list of other ingredients. Here's what's in it.

• goBHB® (as Sodium Beta-Hydroxybutyrate and Beta-Hydroxybutyrate Acid) - 4,000mg

  goBHB is Ketone Labs' trademarked form of beta-hydroxybutyrate, the body's predominant circulating ketone. Unlike most energy ingredients that work through stimulant pathways, BHB functions as a direct fuel substrate. Your cells take it up and oxidize it via acetyl-CoA to generate ATP in the mitochondria, bypassing the glycolytic steps that glucose requires.^[1] This makes BHB a clean, fast-access energy source available regardless of your current diet or metabolic state.

  At 4,000mg per sachet, Let's Go! delivers a clinically relevant dose. Research has shown that doses in this range reliably elevate circulating BHB into the nutritional ketosis range, giving your brain and muscles access to ketone fuel within roughly 30 to 60 minutes of consumption.^[2]

  BHB is also more than a fuel molecule. It acts as a signaling metabolite that inhibits class I histone deacetylases (HDACs), driving expression of oxidative stress-resistance genes.^[3] Separately, BHB activates receptors on immune and adipose cells, suppressing the inflammasome and reducing pro-inflammatory cytokines.^[4] These receptor-level effects are separate from its caloric value and likely explain much of the broader research interest in BHB supplementation. For a comprehensive overview of the science, our BHB Supplements: The Ultimate Guide to Exogenous Ketones is worth bookmarking.

  

  Exogenous BHB is now for everyone—from athletes needing endurance to those boosting brain function. Offering clean, lasting energy, BHB is proving versatile and backed by research.

  The Ketone + Brain + Longevity Connection

  One area drawing additional attention is the brain's fuel flexibility across the lifespan. Research suggests that as women age and estrogen levels shift, cerebral glucose metabolism (the brain's primarily-used energy pathway) can become less efficient, creating a potential energy gap that may affect mood, cognition, and mental resilience.^[5] BHB bypasses this issue entirely because it enters the brain through a separate transporter pathway, offering an alternative fuel that doesn't depend on glucose metabolism working optimally. This is the science behind the product's emphasis on brain health: not as a limitation to that audience, but as a concrete example of who benefits most from metabolic flexibility.

  Let's Go! combines both sodium BHB and BHB free acid in its formula. The salt form provides palatability and fast buffering of the acid load, while the free acid maximizes the molar dose of actual BHB delivered per gram, a thoughtful approach to hitting an effective dose in a small 15mL sachet.

  What New Research Is Telling Us (2025-2026)

  A productive stretch of BHB research has published over the past year and a half, and the results are worth covering in some detail:

  • Body Composition and Lean Mass

    

    A 2025 randomized controlled trial out of Brigham Young University ran 51 overweight adults through eight weeks of caloric restriction with or without BHB salt supplementation twice daily.^[6]

    Within the BHB group, fat mass dropped approximately 2kg (p<0.05 vs. baseline), body fat percentage improved (p<0.01), and the lean-to-fat mass ratio shifted favorably (p<0.05). The placebo group did not show significant changes in any of these measures. Notably, lean mass was largely preserved in the BHB group with no decline in resting metabolic rate, and LDL cholesterol decreased within the BHB group. These are within-group improvements, but the pattern is meaningful in a population where caloric restriction typically erodes both fat and muscle.^[6] The researchers also noted the translational relevance of these findings for people using GLP-1 medications, where lean mass loss can make up 40% of total weight lost.

  • Sleep Quality

    A 2025 double-blind, placebo-controlled trial tested D-BHB supplementation at 1.5g and 2.9g per day over 14 days in 90 healthy adults with poor baseline sleep scores. Both doses improved self-reported scores for alertness on rising and dream quality versus placebo. The lower dose also improved sleep initiation and maintenance, while the higher dose improved feelings of refreshment upon waking.^[7]

    We covered this study in more depth in Sleep Deeper with D-BHB: Research Confirms Ketone Supplement Improves Sleep Quality.

  • Cognitive Vigilance

    A 2026 randomized controlled trial from Nova Southeastern University enrolled 136 healthy young adults and gave them a single 2g dose of D-BHB, L-BHB, or placebo.^[8] Both BHB groups showed fewer attentional lapses than placebo (p=0.004). The L-BHB group also showed significantly faster reaction time compared to placebo (p=0.029). Exploratory within-group analyses showed small but consistent improvements in both BHB arms with no change in the placebo group.^[8] These results are preliminary at this dose and population but support the mechanistic rationale for BHB's cognitive focus claims.

  • Hepatic Safety of BHB Salts

    

    Research shows BHB ketones can significantly improve sleep quality! Study found 1.5-2.9g of D-BHB taken before bed enhanced multiple sleep parameters including easier falling asleep and feeling more refreshed upon waking.^[9]

    Two recent preclinical papers have clarified an important distinction in the ketone category. A 2025 study by Ari and D'Agostino at the University of South Florida compared chronic administration of ketone salts, ketone esters, and 1,3-butanediol (BD) in rats over four weeks. Ketone salts preserved near-normal liver architecture, maintained low inflammatory markers (TNF-α), and showed the lowest fat droplet accumulation. Ketone esters and BD induced steatosis, vascular congestion, and elevated inflammatory cytokines.^[10]

    A 2026 study from Brigham Young University extended this picture with acute and short-term hepatic data: both D-BHB and L-BHB increased liver ATP acutely while maintaining control-level mitochondrial function, inflammation, and lipid content across eight days of daily administration. BD, in contrast, caused ATP depletion, oxidative damage, and significant triglyceride accumulation.^[11] Together, these two studies make a strong case for BHB salts (the form used in goBHB) as the safest available exogenous ketone source for regular use.

  Given Let's Go!'s format as a daily supplement, this distinction matters. You're not choosing between equal options, and the current evidence points clearly to salt-based BHB as the appropriate choice for consistent, ongoing use.

• Liposomal Micelle Matrix - 2,000mg

  

  This is what makes Let's Go! different. Phosphatidylcholine (PC) is the principal structural phospholipid in human cell membranes and the foundation of Let's Go!'s liposomal delivery matrix. Sourced from sunflower lecithin, it forms the bilayer spheres that encapsulate goBHB, creating structures that closely mimic cell membranes to support passage through the GI tract and uptake into circulation.

  Beyond its delivery role, PC is a dietary source of choline, which the body uses to synthesize acetylcholine and maintain membrane integrity throughout the nervous system. Research has also examined PC's relationship with liver function: a 24-week observational study across 2,843 patients found that polyenylphosphatidylcholine (PPC) adjunctive therapy was associated with improved liver echogenicity in 68.3% of participants (p<0.05 vs. baseline).^[12] Those were NAFLD patients receiving PC alongside standard care, so the findings don't extend directly to healthy users, but they do reflect meaningful biological activity at comparable doses.

  How Liposomal Delivery Works

  Liposomes are phospholipid bilayer spheres that encapsulate water-soluble ingredients like BHB, shielding them from the digestive environment and enabling uptake through the intestinal wall via endocytosis rather than passive diffusion. Because the structure mirrors cell membranes, it bypasses much of the first-pass degradation that limits conventional oral delivery.

  

  The evidence is building across numerous nutrient classes (although no studies directly on BHB yet). A 2022 randomized crossover trial found liposomal mineral delivery produced meaningfully higher plasma concentrations than non-liposomal forms.^[13] A 2023 pharmacokinetic analysis confirmed superior absorption profiles for liposomal vs. non-liposomal multivitamin/mineral products.^[14] BHB-specific liposomal data is still emerging, but the delivery mechanism isn't nutrient-dependent: the bilayer physics apply regardless of cargo.

  At 2,000mg, this is a substantive inclusion. It's the structural backbone of the entire formula, and it works in direct concert with the D-alpha tocopherol below, which protects the phospholipid matrix from oxidative breakdown.

• Vitamin E (as D-alpha Tocopherol) - 8mg

  At 8mg (50% DV), Vitamin E in its D-alpha tocopherol form is a functional inclusion, not a headline ingredient. The "D-alpha" designation matters: it's the natural stereoisomer, which research shows is absorbed and retained by the body more efficiently than the synthetic dl-alpha form found in lower-quality supplements.^[15]

  

  Marc Lobliner, President of Ketone Labs, joins the PricePlow Podcast to explain why goBHB will become bigger than creatine, discussing applications from concussion protocols to evening pre-workouts on Episode #186.

  Its role here is tied directly to the liposomal matrix. Tocopherol is a chain-breaking antioxidant that interrupts lipid peroxidation in phospholipid membranes, which makes it a natural fit in a phospholipid-based delivery system where oxidative degradation is the primary stability concern. At this dose, it's doing a specific job (protecting the matrix) rather than serving as a standalone antioxidant supplement.

• Electrolytes: Sodium - 500mg

  Sodium is the body's primary extracellular cation, governing fluid distribution between compartments and supporting normal nerve and muscle signaling. Sweat losses during exercise can deplete it at 1.4g to 4.8g per hour depending on intensity and individual variation, and replacing that deficit matters: sodium in ingested fluids maintains vasopressin levels and improves fluid retention compared to plain water, directly supporting rehydration.^[16]

  At 500mg (20% DV) per sachet, Let's Go! delivers a practical electrolyte dose alongside its BHB payload. The sodium comes directly from the sodium BHB salt, so this is an efficient inclusion: one ingredient carries both the ketone molecule and the electrolyte load.

How to Use Let's Go!

Take 1 to 2 sachets daily. The brand identifies four useful timing windows:

• Morning: kick off the day with ketone fuel before your brain has to shift gears
• Pre-workout: BHB can serve as an accessible fuel source that works alongside carbohydrates
• Midday slump: when afternoon fatigue hits and you'd rather not add more caffeine
• Before key moments: presentations, interviews, big meetings, or any situation where you need focused, clean energy

The sachet format makes this practical in a way capsules and powders aren't. It's 15mL, it's ready to go, and it doesn't require any mixing.

Who It's For

Let's Go! is a good fit for high-performers who've maxed out on stimulants or want energy support that doesn't interfere with sleep. That includes competitive athletes in-season, entrepreneurs or parents managing high-demand days, and anyone who's used to reaching for caffeine but needs a cleaner afternoon option. The M.O.M. (Mind On Mission) brand identity behind Let's Go! is purpose-built for this kind of user.

Women navigating perimenopause or other hormonal transitions may also find BHB useful, given the emerging evidence that shifting hormones can reduce the brain's efficiency with glucose as a primary fuel. The caffeine-free format also matters here: it supports mood stability without the cortisol spike that stimulants can trigger during hormonally sensitive phases.

Research suggests ketones may provide crucial brain protection in contact sports. goBHB supplementation offers an alternative energy source when glucose metabolism is impaired after impact. Could this be the next frontier in athlete brain safety?

Stacks Well With

Let's Go! is caffeine-free by design, which gives it a lot of flexibility as an add-on:

• Pre-workouts or energy drinks for athletes who want ketone substrate alongside their stimulant stack
• Nootropic stacks targeting focus and cognitive load without additional stimulants
• Electrolyte drinks if you need more hydration support around long training sessions or endurance work

Flavors Available

Let's Go! currently comes in two flavors: Tangy Citrus and Sour Watermelon. Both are available individually or as a combination box. Below is an up-to-date list of flavors seen by the PricePlow machine:

Conclusion: A Novel Format for a Maturing Ingredient

Could BHB become as universal as creatine? This cellular energy compound delivers clean mental focus without stimulation, actually improves sleep quality, and supports metabolic health. goBHB from Ketone Labs is leading the bulk powder revolution that makes therapeutic doses accessible.

The supplement industry has spent years proving out BHB's utility as an energy and cognitive ingredient. What Let's Go! adds is a delivery format that's genuinely new: liposomal gel in a portable sachet, with a clean label and no caffeine. At 4000mg goBHB per serving, the dose is serious, and the phospholipid delivery system is a meaningful differentiator in a category that's mostly competed on flavor and convenience of powders.

For a deeper look at goBHB's research history and how it compares to traditional supplement staples, check out our pieces on BHB Supplements: The Ultimate Guide to Exogenous Ketones and Is goBHB the Next Creatine?. And keep an eye on PricePlow for updates as new flavors and the upcoming BHB science coverage rolls out.

Bonnie Barber built Let's Go! around a real problem: the energy and cognitive gaps that busy, high-performing women often hit, especially as hormonal shifts change how the brain handles fuel. The science backs her up, and the format finally makes the solution convenient enough to fit the life she's describing.