Pre workouts are like dress shirts. You can have a different one for every day of the week. Some days you’re really feeling a certain flavor and go in one direction, other times you’ll need a huge hit of energy just to get moving and pick a different one.
With the wide range of options available, sometimes it can be dizzying to figure out which one to go for. When you come to a crossroads like this, it’s time to reach into the cupboard and choose a pre workout that hits all the right notes when it comes to energy, focus, endurance, and pumps.
Pre-Rx 2.0 is the brand new pre workout from Proccor that is a massive upgrade from its predecessor and looks to deliver on ALL fronts. But will it land a spot on our Top 10 Pre Workouts list?
We’ll reveal the panel below, but first, make sure to check the best deal and sign up for PricePlow alerts:
Pre-Rx 2.0 Ingredients
Pre-Rx 2.0 contains a hefty 21g scoop made up of 13 fully dosed ingredients including goodies like Betaine, Creatine, and Beta Alanine. You can also see the exact amounts of all the other ingredients thanks to the completely open label:
CliniForm® Performance Blend
Citrulline Malate (6g)
This is how you start of a performance blend, with a nice full dose of citrulline malate. This is a dual-headed monster when it comes to pumps and performance.
Most associate it with being a superior arginine/nitric oxide (NO) booster, but that only scratches the surface. Citrulline reduces fatigue and soreness while improving your overall training capacity.[2,3] This enables you to workout harder for longer periods of time, which ultimately leads to better gains.
Beta Alanine (3.2g)
When looking to improve your endurance, strength, and sports performance, there’s no better place to turn to than Beta Alanine. Once ingested, it binds to histidine in muscle cells to form carnosine.
Carnosine buffers the accumulation of lactic acid in skeletal muscle which helps reduce the “burn” you feel when doing high volume training or endurance sports.
Pre-Rx 2.0 contains the full clinical dose of 3.2g which will help you increase power output, strength, muscular growth, and most importantly endurance and stamina.[5,6,7]
Creatine MagnaPower® (3g)
Developed by Albion Nutrition, Creatine MagnaPower is a patented from a creatine also known as magnesium creatine chelate. Here, creatine monohydrate is chelate bonded to a magnesium salt to improve absorption and bioavailability in the body.
While the current research MCC isn’t any more effective than monohydrate, we support its inclusion due to the additional magnesium it contributes to the diet. Most of us simply don’t get enough of this essential mineral in our diets. It’s one of the main reason ZMA works so well for a wide range of people.
More people are seeing a solid reason for using betaine, as studies have repeatedly shown it to improve power, endurance, and muscle protein synthesis.[10,11,12]
Additional research also shows betaine reduces muscle soreness and potentially enhances the body’s production of creatine. Like every other ingredient so far in Pre-Rx 2.0, we get the full clinical dose of 2.5g.
Taurine is a conditionally essential amino acid that’s stored predominantly in the brain, heart, and skeletal muscle of the body. It’s acts as a cell volumizer in the body, helping to pull additional water and nutrients into the muscle cells, which sets the stage for some pretty nice “water-based’” pumps.
Additionally, taurine may improve mental focus since such a vast amount is stored in the brain. We’ve noticed more and more pre workouts including this ingredient as of late and are beginning to think they’re on to something when using a strong dose like the one here.
Our last performance enhancer, and another cell volumizer, is the patented high-yield glycerol known as HydroMax®. Regular glycerol monostearate contains only 25% glycerol by weight whereas this form contains 65%. Basically you get more of what you want (glycerol) and less of what you don’t (saturated fat).
HydroMax® turns your muscles into a super-absorbent sponge that sucks up extra water to store. This creates a state of “hyperhydration” that leads to increased endurance[18,19] and further fuels those water-based pumps we just mentioned.
Make sure to drink plenty of water when using HydroMax pre workout (at least 16 oz of water) to get the most from this ingredient.
Focus, Pump, & Stim Blend
Tyrosine is a non-essential amino acid widely used to enhance focus during your workouts. It increases the production of dopamine and noradrenaline, two highly important neurotransmitters in the body. In addition to improving focus and overall cognition, tyrosine also helps reduce symptoms of stress and anxiety.[20,21]
VitaCholine® is a patented form of choline bitartrate manufactured by Balchem. Most associate choline products with improving cognition, since it forms the backbone of the “learning transmitter” acetylcholine. However, choline also imparts performance benefits for athletes.
During intense physical activity or sporting event, choline levels become rapidly depleted which can lead to impaired performance.[24,25] Supplementing with choline prior to your workout or competition will bolster your choline reserves and enable you to continue to perform at your peak output.
To boost your overall mood, Pre-Rx 2.0 contains PhenylThin®, a patented form of Phenethylamine (PEA). This molecule functions as a neuromodulator in the central nervous system. It’s naturally found in nature, but more often it’s supplemented increasing levels of the “feel good” neurotransmitter dopamine.
The only drawback to PEA is that its effects last rather briefly, as it’s quickly broken down by your MAO enzymes.[27,28]
Not much research has been performed on PEA in terms of enhancing exercise performance, but the increase in catecholamines should give you an extra boost in motivation to get in the gym.
PurCaf® is a patented form of caffeine that’s 90% organic pure caffeine extract derived from water-extracted green coffee beans.
Natural caffeine confers all the same energy-boosting and performance-enhancing qualities that more conventional synthetic forms of the stim offer. However, should you be a non-GMO fanatic, you can sleep sound at night knowing your caffeine source it’s naturally sourced.
L-theanine has become increasingly popular in pre workouts to smooth out the harsh kick from high doses of caffeine and other stimulants, that some users experience. However, theanine does much more than that…
It also enhances the cognitive effects of caffeine,thereby improving focus, and helps reduce fatigue, stress, and anxiety.[31,32]
Typically, we find a 3:1 caffeine:theanine ratio to be the sweet spot, and Pre-Rx 2.0 hits it right on the money.
Synephrine HCl (50mg)
Synephrine is a naturally occurring alkaloid found in the Citrus Aurantium plant. It’s a potent Beta-2 and Beta-3 adrenergic receptor agonist[33,34] that liberates stored triglycerides and releases them into the bloodstream, a process known as “lipolysis”. This enables your body to essentially “burn fat” for fuel and save your glycogen stores for high intense activities.
Huperzine A (50mcg)
While choline supplements help to directly increase production of acetylcholine, Huperzine A indirectly increases it. This molecule inhibits acetylcholinesterase, the enzyme responsible for the breakdown the acetylcholine. Negating the effects of acetylcholinesterase means more acetylcholine is available which ultimately leads to better focus.
Another interesting tidbit about huperzine, is that it protects against the “neuron death molecule” glutamine, and possibly help create new brain cells thereby making it “neurogenerative.”
With such a hefty scoop size chock full of ingredients, your body’s going to need some help absorbing each and every gram of performance enhancing goodness. Pre-Rx 2.0 contains the patented black pepper extract BioPerine® to improve the bioavailability and absorption of all the other compounds.
Pre-RX 2.0 will be come in 20 servings tubs. At the moment, though, there is only one flavor: Jolly Green Apple. Hopefully more options will roll out once the product makes its full launch at the end of this week.
When you’re suffering from pre workout indecision, there’s only one prescription to cure your ailments and it’s Preccor’s Pre-Rx 2.0. Whether you need a stiff kick in the pants, a boost in power, or just looking for a bad ass pump, Pre-Rx 2.0 delivers the goods on every front.
This is quite the comprehensive profile, and provided it is priced competitively, could be a HUGE seller on the market. You can fully expect to see this one popping up on our Best Pre Workout guide soon!
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- Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
- Perez-Guisado; Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.; Department of Medicine, University of Córdoba; 2010; Retrieved fromhttp://www.ncbi.nlm.nih.gov/pubmed/20386132
- Hickner, R; L-citrulline reduces time to exhaustion and insulin response to a graded exercise test.; Human Performance Laboratory, East Carolina University; 2006; Retrieved fromhttp://www.ncbi.nlm.nih.gov/pubmed/16679980
- Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
- Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
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- Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
- Lee EC, et al. Ergogenic effects of betaine supplementation on strength and power performance. J Int Soc Sports Nutr. (2010)
- Effect of betaine supplementation on power performance and fatigue
- del Favero S, et al Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance . Amino Acids. (2012)
- holewa, J; Effects of betaine on body composition, performance, and homocysteine thiolactone.; Department of Kinesiology, Recreation, and Sport Studies, Coastal Carolina University; 2013
- Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise.
- Hoffmann, E.K., I.H. Lambert, and S.F. Pedersen, Physiology of cell volume regulation in vertebrates. Physiol Rev, 2009. 89(1)
- Alford, C., H. Cox, and R. Wescott, The effects of red bull energy drink on human performance and mood. Amino Acids, 2001. 21(2)
- Glanbia Nutritionals, Inc; HydroMax: a better glycerol for sports nutrition; NewHope360; 2014
- van Rosendal, S; Guidelines for glycerol use in hyperhydration and rehydration associated with exercise.; School of Human Movement Studies, The University of Queensland; 2010
- Wingo, J; Influence of a Pre-Exercise Glycerol Hydration Beverage on Performance and Physiologic Function During Mountain-Bike Races in the Heat; University of Connecticut, Department of Sport, Leisure, & Exercise Science; 2004
- Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
- Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
- Buchman AL, Jenden DJ, Roch M. Plasma free, phospholipid-bound and urinary free choline all decrease during a marathon run and may be associated with impaired performance. J Am Coll Nutr 1999;18(6):598-601.
- Conlay LA, Wurtman RJ, Blusztajn JK, Lopez-Coviella I, Maher TJ, Evoniuk GE. Decreased plasma choline concentrations in marathon runners. NEJM 1986 October 2;315:892.
- Narang, D; Trace Amines and Their Relevance to Psychiatry and Neurology: A Brief Overview; Department of Pharmacology, University of Alberta; February 20, 2011; Retrieved fromhttp://www.psikofarmakoloji.org/pdf/21_1_13.pdf
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- Shannon, H; Physiologic effects and plasma kinetics of beta-phenylethylamine and its N-methyl homolog in the dog.; J Pharmacol Exp Ther. 1982 Oct;223(1):190-6.; Retrieved fromhttp://www.ncbi.nlm.nih.gov/pubmed/7120117
- Giesbrecht, Timo, et al; “The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness”; Nutritional Neuroscience; 2010
- Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. (2007)
- Owen GN, et al. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. (2008)
- Zhao, Q; Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; 2002
- Ved, H; Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.; Division of Biochemistry, Walter Reed Army Institute of Research; 1997
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