Unmatched Supps Peptide PRE: Four Peptide Ingredients, Zero Stimulants

Throughout 2026, bodybuilder and biohacker Kris Gethin has turned Unmatched Supps into one of the most peptide-forward brands in sports nutrition, with launches like Unmatched Supps Dileucine and Collagen Peptide-6.

Three blood flow peptides, one focus peptide, no stimulants. Unmatched Supps Peptide PRE stacks PepForm citrulline, VasoDrive-AP, and PeptiPump with the brand-new PeptiDRIVE-LNDP. Train late without the caffeine.

Now that approach comes to the pre-workout shelf with Unmatched Supps Peptide PRE, a non-stimulant pre-workout built around four peptide ingredients:

1. VasoDrive-AP®
2. PeptiDRIVE-LNDP™ (new!)
3. PeptiPump™
4. PepForm® L-Citrulline

Those peptides sit on top of a full stim-free base: 8g of total L-citrulline, 3.2g of beta-alanine, 2.5g of betaine anhydrous, 2g of taurine, 1g of L-tyrosine, pine bark extract, and three electrolytes. Three of the four peptide ingredients target blood flow, and pine bark extract adds another vascular angle, so the formula doesn't lean on citrulline alone.

Peptide PRE: Our First Product Launch with PeptiDRIVE-LNDP

The fourth peptide is the one that caught our attention. PeptiDRIVE-LNDP is a cognitive peptide from Japan's Asahi Group Foods (same as with VasoDrive-AP), and Peptide PRE is the first finished supplement we've seen use it. Better yet, Unmatched dosed it to match the amount used in human research, giving this stim-free formula a focus component that most pump products skip.

There's no caffeine anywhere on the label, so Peptide PRE fits evening sessions, caffeine breaks, or a stack with your favorite stimulant pre-workout. It also follows Unmatched's naturally flavored and sweetened standard, with three candy-inspired flavors at launch. Check the latest prices and availability below, then we'll break down the formula:

Unmatched Supps Peptide PRE Ingredients

Each one-scoop serving (24.4g to 24.8g, depending on flavor) provides the following:

• L-Citrulline (as Vegan Fermented L-Citrulline and PepForm® L-Citrulline) - 8000mg

  Peptide PRE's pump base starts with 8g of L-citrulline, an amino acid your kidneys convert into L-arginine, the substrate your blood vessels use to make nitric oxide. In one crossover trial, 6g per day of citrulline raised plasma arginine as much as the same dose of arginine, but only citrulline improved tolerance to severe-intensity cycling and total work completed.^[1] Across 12 studies, a meta-analysis found a significant benefit for citrulline on high-intensity strength and power.^[2]

  The dose lines up with some of the most relevant recent research. In a 2025 trial, resistance-trained men taking 8g of L-citrulline daily for six weeks improved upper-body repetitions to failure compared to placebo, performing similarly to a group taking 12g of citrulline malate.^[3] So realize that it's really L-citrulline driving the train if you ever see "citrulline malate" on a competitor's label.

  PepForm L-Citrulline Added

  Unmatched splits the 8g between vegan fermented L-citrulline and PepForm® L-Citrulline from Glanbia Nutritionals, though the label doesn't disclose the ratio. PepForm technology binds free-form amino acids to peptides isolated from whey, which Glanbia says improves solubility, taste, and utilization. It's more of a delivery claim than an efficacy claim, and we haven't found published human research on PepForm citrulline itself, so the research above speaks to the citrulline it carries.

  Regarding the milk allergen warning, the whey carrier is one reason Peptide PRE contains "milk" (same goes for two of the other peptide ingredients inside).

• Beta-Alanine - 3200mg

  Beta-alanine combines with histidine in muscle to form carnosine, which buffers the acidity that builds up during hard, high-rep sets. The International Society of Sports Nutrition's position stand concludes that daily beta-alanine raises muscle carnosine and improves exercise performance, with the clearest effects in efforts lasting one to four minutes.^[4] A meta-analysis reached a similar conclusion, finding benefits for exercise lasting 60 to 240 seconds but not for efforts under a minute.^[5]

  

  Since carnosine builds up over weeks, total intake matters more than any single serving. The studies in that meta-analysis used a median total of 179g of beta-alanine.^[5] At 3.2g per day, Peptide PRE reaches that total in about eight weeks of consistent use. That's below the 4g to 6g daily range the ISSN describes, and the same position stand notes that a temporary tingling sensation called paresthesia is beta-alanine's only reported side effect.^[4]

• Betaine Anhydrous (TMG) - 2500mg

  Betaine anhydrous, also called trimethylglycine, is a methyl derivative of glycine first isolated from sugar beets. Proposed mechanisms include increased creatine synthesis and cellular hydration, though researchers note the exact pathways remain unclear.^[6]

  The broadest evidence comes from a 2024 meta-analysis of 17 studies, which found that taking betaine for at least seven days improved maximal strength, especially in the lower body, along with vertical jump performance after excluding a low-quality study.^[7] It didn't find significant effects on upper-body strength, sprint power, or muscular endurance.

  Peptide PRE's 2.5g matches the dose from a six-week trial in which strength-trained men improved body composition, arm size, and bench press work capacity compared to placebo.^[8] In another trial, 14 days of twice-daily betaine increased bench throw power and isometric bench press force.^[9]

• L-Taurine - 2000mg

  Taurine is an amino sulfonic acid found in high concentrations in skeletal muscle, where it's involved in regulating ion channels, cell volume, and membrane stability.^[10] It has no chiral center, so the "L-" on many labels is a naming convention rather than a different form.

  A 2025 meta-analysis of 23 randomized trials found that a single dose of taurine was associated with small-to-moderate improvements in overall exercise performance, with benefits most apparent in aerobic endurance, strength and power, and agility tasks.^[11] The researchers found no clear dose-response pattern across the common 1g to 6g range, which includes Peptide PRE's 2g. They also rated the certainty of the evidence as low, so taurine is best viewed as a supporting ingredient here rather than a headliner.

  There's also some evidence regarding mitochondrial health^[12] osmotic support,^[10] and heat stress prevention,^[13] which further makes us like taurine, especially at a solid dose like this.

• L-Tyrosine - 1000mg

  

  L-tyrosine is the amino acid your body uses to make dopamine and norepinephrine, the catecholamine neurotransmitters behind focus and drive. A review of the cognitive research concluded that tyrosine can enhance performance in short-term stressful or mentally demanding situations, when those neurotransmitters are temporarily depleted, while its effects on physical exercise appear minimal.^[14]

  A 2024 trial shows the use case. During a stressful virtual reality training drill paired with a cognitive challenge, 2g of L-tyrosine reduced missed responses on a Stroop test compared to placebo, though it didn't change salivary stress markers.^[15] Peptide PRE's 1g is half that amount, so it's best viewed as a complement to PeptiDRIVE-LNDP, giving the formula a second focus ingredient without adding a stimulant.

  Now let's get to the new stuff everyone's been waiting on:

• PeptiDRIVE-LNDP™ (Lactononadecapeptide) - 632mg

  This is the ingredient we're most excited to try. PeptiDRIVE-LNDP™ is lactononadecapeptide (LNDP), a 19-amino-acid peptide from milk's beta-casein. Researchers identified it in Lactobacillus helveticus-fermented milk, where it was the most effective of the casein peptides they tested in a mouse memory model.^[16] Asahi Group Foods now produces it through controlled enzymatic hydrolysis of casein, and we covered its full research profile in our ingredient guide linked above.

  The dosing is on point. According to distributor Maypro, 632mg of PeptiDRIVE-LNDP delivers 2.4mg of the peptide, and human trials have used 2.1mg to 4.2mg per day.^[17] The most relevant trial for a pre-workout is an acute one, too: In healthy men aged 30 to 59 placed under a mental workload, a single dose of LNDP tablets improved composite and verbal memory compared to placebo, along with processing speed, executive function, and cognitive flexibility.^[18] Over eight weeks, a fermented milk drink that Maypro says provided 2.4mg of LNDP daily improved attention and delayed memory in healthy middle-aged adults.^[19]

  LNDP also holds up in digestion: it retained over 90% stability after two hours with gastrointestinal enzymes and crossed intestinal cell layers via the PEPT1 transporter in lab models.^[20] The research teams attribute its effects to increased BDNF expression and acetylcholine release, based largely on preclinical work. The caveat is that every LNDP trial measured cognition outside of training, mostly in Japanese adults, so in Peptide PRE it's the focus ingredient rather than a pump or strength ingredient.

  

  Read our article titled "PeptiDrive-LNDP: A New Cognitive Nootropic Peptide From Maypro Industries" for more information.

• VasoDrive-AP® (Isoleucyl-prolyl-proline (IPP) and Valyl-prolyl-proline (VPP)) (from hydrolyzed milk protein) - 254mg

  VasoDrive-AP® is a casein hydrolysate containing two lactotripeptides, IPP and VPP, that inhibit angiotensin-converting enzyme (ACE). Less ACE activity means less of the vasoconstrictor angiotensin II, which gives VasoDrive-AP a different route to blood flow than nitric oxide precursors like citrulline. In a placebo-controlled crossover trial in men with mild hypertension, one week of IPP and VPP produced about 44% higher maximum forearm blood flow than placebo, without changing blood pressure.^[21] Our VasoDrive-AP guide linked above covers its three decades of research.

  The newest research targets lifters directly. In a 2026 trial led by Asahi researchers, resistance-trained men took either 1.7mg or 3.4mg of the tripeptides daily for four weeks. The higher dose increased post-workout thigh circumference compared to placebo, increased lean mass from baseline, and improved post-exercise fatigue and next-morning training motivation scores, while the lower dose improved subjective pump ratings.^[22]

  Maypro's product literature lists 3.4mg of IPP and VPP per 508mg of VasoDrive-AP, which puts Peptide PRE's 254mg at roughly 1.7mg. That matches the trial's lower dose, which improved how the pump felt, while the measurable size changes came at twice the amount.

  Like LNDP, VasoDrive-AP traces back to Japanese research on L. helveticus-fermented milk, so Peptide PRE pairs two casein peptides from the same lineage, one for blood flow and one for focus.

• Pine Bark Extract (95% Proanthocyanidins) (Pinus pinaster) - 250mg

  French maritime pine bark extract is concentrated in procyanidins, along with smaller compounds like catechin, taxifolin, and phenolic acids. The small compounds are absorbed quickly, while gut bacteria break the larger procyanidins down into absorbable metabolites.^[23]

  

  Unmatched Supps Dileucine features 2g DL185® dipeptide that reaches plasma 185% faster than free leucine. Research shows 60% greater muscle protein synthesis and significant strength gains. Superior anabolic support through dedicated peptide transporters.

  Its vascular research is why it's here. In a crossover trial in patients with stable coronary artery disease, 200mg per day of a branded French maritime pine bark extract, improved flow-mediated dilation (a measure of endothelial function) from 5.3% to 7.0% over eight weeks while reducing a marker of oxidative stress.^[24] In rat aortas, pine bark extract relaxed blood vessels by activating endothelial nitric oxide synthase (eNOS), the enzyme that converts arginine into nitric oxide.^[25] That gives Peptide PRE a third vascular mechanism alongside citrulline's arginine supply and VasoDrive-AP's ACE pathway.

  One dose-translation caveat: the most heavily-studied branded form is standardized to 65% to 75% procyanidins.^[23] Peptide PRE uses an unbranded extract standardized to 95% proanthocyanidins instead. The 250mg dose is beyond the trials' 200mg, but results from one extract don't necessarily transfer one-to-one to another, and the human research centers on vascular function rather than exercise performance.

• PeptiPump™ Lentil Protein Hydrolysate - 200mg

  PeptiPump™ is a lentil protein hydrolysate from Nuritas, which used its AI discovery platform to identify the network of bioactive peptides inside it. Nuritas positions it as a stimulant-free pump ingredient that inhibits ACE and supports nitric oxide production, which would overlap with VasoDrive-AP's pathway from a plant source instead of milk. PricePlow readers may recognize it from C4's 2024 pre-workout lineup.

  The evidence is still early. We haven't found published human trials on PeptiPump itself, so its benefits are developer-supported rather than independently demonstrated. In Peptide PRE, it's best treated as an emerging addition to the better-studied citrulline and VasoDrive-AP rather than a primary driver of the formula.

• Calcium - 90mg (100mg in Sour Lemon Candy)

  

  Unmatched Supps BH2K isn't your typical pre-workout. CreGAAtine technology, zero artificial ingredients, and a stimulant that won't wreck your sleep. Kris Gethin and Doug Miller created something different here.

  Calcium is essential for muscle contraction. The Supplement Facts panel doesn't specify its source, and the amount varies slightly by flavor, from 90mg on the Grape Candy panel to 100mg in Sour Lemon Candy.

• Sodium (as Sodium Citrate) - 200mg

  Sodium is the main electrolyte lost in sweat, and it helps your body hold onto the fluid that supports hydration and blood volume during training. Peptide PRE provides 200mg from sodium citrate.

• Potassium (as Potassium Citrate) - 200mg

  Potassium works alongside sodium to maintain fluid balance and normal muscle and nerve function. It also supports vasodilation, which is why we love to see a solid hit of it in pump formulas. Peptide PRE includes 200mg coming from potassium citrate.

Flavors Available

Peptide PRE launched with three candy-inspired flavors: Sour Lemon Candy, Grape Candy, and Green Apple Candy. True to Unmatched's naturally flavored and sweetened standard, each uses natural flavors and stevia extract, and Sour Lemon Candy gets its color from beta carotene.

Here's an up-to-date list of all flavors of Unmatched Supps Peptide PRE:

How to Use

• When to take it: Mix one scoop with 10 to 14 fluid ounces of water and drink it about 15 to 30 minutes before training.
• Other notes: Unmatched suggests new users start with half a scoop to assess tolerance. The formula contains milk, so it isn't a fit for anyone avoiding dairy.

Stacks Well With

• Unmatched Supps BH2K (contains enfinity paraxanthine as a stimulant): Peptide PRE's label recommends stacking it with BH2K, Unmatched's all-natural pre-workout featuring CreGAAtine. Since Peptide PRE has no creatine, the pairing covers that base.

Who It's For

• Stimulant-free trainees: If you train late, take breaks from caffeine, or don't tolerate stimulants, Peptide PRE delivers full doses of pump and performance ingredients with no caffeine on the label.
• Pump chasers looking for something new: Beyond its 8g citrulline base, it adds three more vascular ingredients that work through different pathways, plus a cognitive peptide that is new on the market and we've never seen in this category yet.

Conclusion: Pumps and Focus Without the Stimulants

Peptide PRE brings the peptide-first thinking behind Unmatched products like Longevity Sleep to a stim-free pre-workout, and the result covers more ground than a typical pump formula. The base is built on established doses: 8g of L-citrulline matching recent resistance-training research, 2.5g of betaine at a research-matched dose, and 3.2g of beta-alanine for steady carnosine loading. VasoDrive-AP and pine bark extract add two more vascular mechanisms on top, with PeptiPump contributing an emerging plant-based option.

The headline, though, is PeptiDRIVE-LNDP. A cognitive peptide dosed to match its human trials is rare enough, and this is the first product we've seen carry it. Paired with L-tyrosine, it gives Peptide PRE a focus component that pump products usually skip, making it one of the few stim-free pre-workouts built for the mind as well as the muscle.

For anyone who wants pumps and focus without caffeine, or a stim-free partner for BH2K, Peptide PRE is worth a look. Check PricePlow for current prices and availability below, and sign up for Unmatched Supps news alerts so you'll hear about the next launch.