Unmatched Supps Dileucine: DL185® Peptide Technology for Muscle Protein SyntheKris

Unmatched Supps Dileucine features 2g DL185® dipeptide that reaches plasma 185% faster than free leucine. Research shows 60% greater muscle protein synthesis and significant strength gains. Superior anabolic support through dedicated peptide transporters.

Leucine has long been recognized as the primary trigger for muscle protein synthesis, but what if there's a more efficient way to deliver its anabolic signal? Unmatched Supps Dileucine brings DL185®, a breakthrough dipeptide composed of two leucine molecules bonded together. Far more than just "regular leucine repackaged", dileucine is a functionally different compound that leverages your body's specialized peptide transport systems to deliver faster, stronger muscle-building signals.

Dileucine: A Top-Selling Muscle Building Peptide

The formula features DL185 from NNB Nutrition, one of the supplement industry's most innovative ingredient developers. NNB has built their reputation on creating novel compounds backed by rigorous research (many of which are used throughout the Unmatched line), and DL185 is their latest advancement in amino acid technology. At 2g per serving, Dileucine joins the ranks of Unmatched's bestselling products like ElectraShred and CreGAAtine, delivering clinical doses of cutting-edge ingredients that actually move the needle on performance and recovery.

True to Unmatched's philosophy showcased in products like BH2K Pre-Workout, Dileucine is formulated without artificial additives. This is muscle-building support designed for athletes who refuse to compromise on ingredient quality. In fact, Kris Gethin and Doug Miller's formulas work so well, we're renaming muscle protein synthesis to "muscle protein syntheKris". If you know, you know.

Let's get into the science below, but first, subscribe to PricePlow's Unmatched Supps news and check availability:

Unmatched Supps Dileucine Ingredients

Each 4-capsule serving provides the following:

• DL185® Dileucine - 2000mg

  Dileucine is a dipeptide composed of two leucine molecules bonded together, but this isn't just leucine in a different package. The dipeptide structure allows dileucine to use specialized intestinal transport systems that free amino acids can't access, delivering leucine to muscle tissue faster and more efficiently than standard leucine supplementation.^[1]

  The Dipeptide Advantage

  Your intestines absorb dipeptides through the PepT1 transporter, which moves small peptides across the intestinal wall intact.^[2] This transport system operates independently of free amino acid transporters, meaning dileucine enters circulation through a separate, dedicated pathway. Research demonstrates constituent amino acids absorb faster when presented as dipeptides compared to their free forms.^[2]

  In practical terms, dileucine reaches peak plasma concentrations 185% faster than free leucine, while delivering the same total leucine content.^[3] This rapid delivery may help maximize the anabolic window following training.

  Supporting Muscle Protein Synthesis

  Leucine activates the mTORC1 pathway, which regulates muscle protein synthesis at the ribosomal level.^[3] When you ingest dileucine, it appears to trigger this pathway more effectively than equivalent doses of free leucine.

  A controlled trial comparing 2g of dileucine to 2g of free leucine showed dileucine increased muscle protein synthesis rates by approximately 60%, while free leucine produced no significant change.^[3] Both treatments similarly activated downstream signaling proteins including Akt, rpS6, and p70S6K, yet only dileucine translated those signals into measurable increases in protein synthesis.

  

  Testing DL185: Performance Outcomes

  In a 10-week training study with resistance-trained men, 2g of daily dileucine supplementation produced significant improvements in lower body strength and endurance compared to both leucine and placebo groups.^[4]

  The dileucine group increased leg press 1RM by approximately 40kg more than placebo and showed greater increases in repetitions to failure compared to free leucine.^[4] These weren't untrained beginners experiencing "newbie gains" but experienced lifters following a structured program.

  Dosing and Context

  The 2g dose in Unmatched Supps Dileucine matches the amounts used in research showing enhanced protein synthesis and performance improvements. This dose delivers the leucine content of approximately 3-4g of free leucine but through the more efficient dipeptide pathway.

  For those serious about maximizing training adaptations, dileucine offers a research-backed approach to supporting muscle protein synthesis and recovery. The dipeptide structure isn't just clever chemistry but a functional advantage that human studies have validated.

  Learn more in our articles, DL185 Dileucine: NNB Nutrition's Exclusive Muscle Building Peptide and New Dileucine Research: 2024 Study Shows NNB Nutrition's DL185 Improves Strength.

How to Use

• When to take it: Take 4 capsules after exercise, or in the morning on non-training days for continuous muscle protein synthesis support.
• Timing flexibility: While post-workout is ideal for maximizing the anabolic window, you can take Dileucine anytime to support recovery and muscle preservation.
• Daily limit: Do not exceed 4 capsules in a 24-hour period.

Stacks Well With

• ElectraShred: The hydration and metabolism support from ElectraShred complements Dileucine's muscle-building focus, creating a complete intra-workout or post-workout stack.
• CreGAAtine: Pair Dileucine's enhanced protein synthesis with CreGAAtine's superior creatine delivery for comprehensive anabolic support.

  Alternatively, you can use the following pre-workout, which contains it:

• BH2K Pre-Workout: Start your training with BH2K's energy and pump support, then follow with Dileucine post-workout to maximize recovery and growth.
• INTRA Intra-Workout: For extended training sessions, INTRA's Vitargo and EAAs sustain performance during your workout, while Dileucine handles the recovery phase afterward.

Who It's For

• Serious muscle builders: If you're training hard and want every advantage for hypertrophy, Dileucine's superior activation of muscle protein synthesis delivers measurable results.
• Athletes in calorie deficit: When you're cutting or maintaining low body weight, Dileucine helps preserve lean mass by promoting a positive protein balance even with reduced caloric intake.
• Anyone training fasted: Empty stomach workouts create additional recovery demands. Dileucine's rapid absorption and efficient protein synthesis support make it ideal for these scenarios.
• Those unable to train consistently: Injury, illness, or travel can disrupt your training schedule. Dileucine can help maintain muscle mass during these challenging periods by supporting protein synthesis even with less training stimulus.

Conclusion: Next-Generation Anabolic Support

Unmatched Supps Dileucine is a significant evolution in amino acid supplementation. By partnering with NNB Nutrition to expand DL185's market presence, Unmatched has secured access to one of the most promising muscle-building ingredients backed by clinical research showing superior protein synthesis compared to standard leucine.

ElectraShred Knockout Punch combines hydration with metabolism support. 750mg+ electrolytes, Chromax chromium, taurine & ALCAR in an all-natural formula from Unmatched Supps x Cristy "Code Red" Nickel.

The 2g dose delivers the anabolic benefits that typically require 3-4g of free leucine, making it an efficient addition to any serious training program. Whether you're stacking it with INTRA for complete workout nutrition or using it standalone for targeted recovery support, Dileucine provides the precise muscle-building signal your body needs when it matters most.

This launch continues Unmatched's pattern of bringing innovative, research-backed ingredients to athletes who demand more from their supplements. From CreGAAtine's breakthrough approach to creatine delivery to ElectraShred's comprehensive hydration formula, Unmatched consistently delivers formulas that bridge performance and health without compromise.

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