Bucked Up Flow: Next-Generation Nitric Oxide Capsules with Shoden® and N.O.V8™

Bucked Up Flow: Next-Generation Nitric Oxide Capsules with Shoden® and N.O.V8™

Most pump pills rely on NOS enzymes for nitric oxide production, and NOS activity drops roughly 50% after age 40. Bucked Up Flow uses N.O.V8™, a fermented nitrite blend that bypasses that issue, paired with Shoden® ashwagandha for vascular and adaptogen support.

Bucked Up has built a serious reputation in the pre-workout space, but a dedicated pump pill has been a gap in their lineup. This category is an option for athletes who want to stack stimulant-free circulation support on top of their existing pre-workout, or just want something clean to take on off days to support the cardiovascular system. Bucked Up Flow fills that gap, and it goes well beyond the standard citrulline approach.

Even better, this is an experiential feel-good formula that does more than improve blood flow. The formula anchors itself with Shoden®, Arjuna Natural's patented ashwagandha extract standardized to 35% withanolide glycosides, the highest-concentration form on the market. We've covered Shoden in depth in our Shoden ingredient deep dive and the Arjuna Naturals podcast on Episode #171, and it's genuinely among the most exciting adaptogen innovations of the past several years.

Alongside it, Flow introduces N.O.V8™, a fermented nitric oxide metabolite matrix that approaches vasodilation from a different angle than anything Bucked Up has run before. This means it helps balance healthy blood pressure and vascular benefits while supporting adrenal glands and combating adrenal fatigue in an over-caffeinated pre-workout environment.

Six ingredients, two capsules, zero stimulants. The full breakdown is below, but first, check prices and availability and sign up for our Arjuna Natural news alerts:

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Bucked Up Flow Ingredients

Bucked Up Flow Ingredients

  • Shoden® Ashwagandha (Withania somnifera) - 60mg

    Shoden® is a brilliant way to add a unique experience to a category that's lacked innovation for the past decade. Arjuna Natural standardizes this extract to 35% withanolide glycosides by HPLC, the highest concentration of any commercial ashwagandha form, well beyond its main competitors (5-10%) by a serious margin. That gap matters more than it might first appear:

    Why Standardization Changes the Math

    A 2023 pharmacokinetics crossover trial directly compared WS-35 (the withanolide glycoside-dominant extract underlying Shoden) against a conventional 2.5% withanolide extract at matched total withanolide doses. WS-35 showed a 280-fold higher area under the plasma concentration curve, along with higher peak plasma levels and longer mean residence time.[1] That's why Shoden achieves clinical outcomes at 60mg to 120mg where most other extracts need 300mg to 600mg to approach comparable results.

    The Mechanism Behind a Pump Product

    In a circulation-focused formula, ashwagandha earns its spot through the hypothalamic-pituitary-adrenal (HPA) axis. Chronically elevated cortisol raises blood pressure and promotes vasoconstriction, working directly against the vasodilation goals of the rest of this stack. Shoden helps support healthy HPA axis function, which in turn supports the vascular environment where the other ingredients can operate most effectively.

    A 60-day randomized controlled trial in healthy adults with high stress found that 60mg and 120mg of Shoden reduced morning serum cortisol by approximately 66% and 67%, respectively, versus negligible change in the placebo group.[2] A separate 60-day placebo-controlled study using 240mg Shoden found significant reductions on the Hamilton Anxiety Rating Scale alongside significantly lower morning cortisol, with researchers pointing to HPA axis modulation as the likely mechanism.[3]

    Ashwagandha Evolution: The Rise of Glycoside-Enhanced Extracts

    Shoden brings a new era to ashwagandha supplements with 35% glycowithanolide standardization. Research shows it delivers powerful effects at just 60-120mg daily, compared to 600mg+ with traditional extracts.

    Studied to Support Sleep

    Sleep quality adds another layer. A six-week trial at 120mg Shoden in adults with non-restorative sleep found a 72% improvement in self-reported sleep quality alongside significant gains in sleep efficiency and total sleep time compared to placebo.[4] Better recovery sleep supports the hormonal and cardiovascular environment where training adaptations accumulate between sessions.

    This makes it the perfect ingredient to add to a stimulant-free stack. Whether you're stacking it with a bunch of stimulants and need to take the cortisol edge off a bit, or you're on a stimulant break and need to reset your adrenals, Shoden can help.

    At 60mg, Shoden sits within the studied range, with its exceptional bioavailability profile justifying that efficiency. For the full clinical picture, check out our Shoden ingredient deep dive.

  • L-Theanine - 200mg

    L-Theanine is a non-protein amino acid from green tea that promotes alpha-wave activity in the brain, the frequency range associated with a calm, alert mental state without sedation.[5] It modulates glutamate and GABA receptor activity, supporting a relaxed-but-focused neurological state that's distinct from sedatives or stimulants.[6] At 200mg, this matches doses studied in randomized controlled trials demonstrating improvements in sleep quality, verbal fluency, and executive function after four weeks of daily use.[7] A systematic review found that 200mg to 400mg/day may help support healthy stress management in adults under stressful conditions.[8]

    Bucked Up Flow Bottle

    In Flow, L-theanine complements Shoden's HPA axis support and Rhodiola's acute anti-fatigue activity. Where those adaptogens address physiological stress load, L-theanine adds a cognitive dimension, helping support mental clarity and attentional focus during training without stimulants.

    Also note that if you're stacking Flow with a Bucked Up pre-workout, you'll get the well-studied synergistic effects that theanine has with caffeine.[9][10]

  • Rhodiola Extract (Rhodiola rosea) - 100mg

    Rhodiola rosea at 100mg, standardized to 3% rosavins and 1% salidroside, matches the active compound ratios used in the most-cited clinical research on this adaptogen. Generic extracts with no label spec can vary widely in potency, so the explicit 3:1 rosavin-to-salidroside ratio is a meaningful quality signal.[11]

    Rhodiola's primary mechanism runs through the sympatho-adrenal system (SAS), the pathway governing your acute stress response. A single dose may produce a stimulating effect within 30 minutes that lasts 4 to 6 hours, without the addiction, tolerance, or rebound associated with conventional stimulants.[12] That's a direct complement to Shoden's longer-term HPA axis support: one adaptogen covering the acute stress response, the other the chronic, giving Flow's adaptogen stack two distinct, non-overlapping mechanisms.[13] Rhodiola also delivers benefit with consistent daily use, which makes it a natural fit for a formula you'll take on training and rest days alike.

    Now it's time to get into some pumps:

  • Grape Seed Extract (Vitis vinifera) - 100mg

    Grape Seed Extract (GSE), standardized to 95% proanthocyanidins (OPCs), kicks off the blood flow part of the formula with endothelial support that works alongside N.O.V8™ from a different mechanistic angle.

    GSE polyphenols activate the PI3K/Akt signaling pathway in endothelial cells, triggering phosphorylation of eNOS (endothelial nitric oxide synthase) and producing a dose-dependent vascular relaxation.[14] Where N.O.V8™ delivers pre-formed nitrite to sidestep NOS dependence (discussed below), GSE reinforces eNOS activity upstream while protecting the vascular tissue eNOS depends on from oxidized LDL and lipid peroxidation stress.[15]

    Bucked Up Flow Benefits

    The blood pressure data are consistent across multiple meta-analyses. A 16-trial meta-analysis found significant reductions in both systolic and diastolic blood pressure with GSE supplementation.[16] In athletes, 14 days of GSE supplementation improved flow-mediated dilation and extended time to exhaustion on a progressive cycling test -- effects the researchers attributed in part to enhanced endothelial function in active skeletal muscle.[17]

    The 100mg dose at 95% OPC standardization is consistent with dosages across the reviewed trials, making this a tightly dosed finish to the formula's cardiovascular stack.

  • N.O.V8™ (Fermented Botanical Blend) - 20mg

    N.O.V8™ is the breakout blood flow ingredient here in Bucked Up Flow. It combines fermented lettuce, fermented cabbage, and fermented garlic powders into a stabilized nitric oxide metabolite matrix.

    The mechanism differs from conventional NO ingredients. Citrulline, beet root, and arginine all require nitric oxide synthase (NOS) enzymes to generate NO, and NOS activity declines roughly 50% after age 40.[18] N.O.V8™ delivers pre-formed nitrite, a downstream NO metabolite that activates in the stomach without enzymatic conversion, using the sGC-cGMP-PKG pathway to support vascular relaxation.[19] A randomized controlled trial in healthy adults found that fermented garlic extract containing NO metabolites produced significant increases in carotid artery blood flow and regional cerebral blood flow.[20]

    The acute timeline is also worth noting: A 2025 observational study in hypertension patients found that a single oral dose of fermented garlic extract containing NO produced significant reductions in both systolic and diastolic blood pressure within 15 minutes, along with measurable improvements in arterial stiffness markers including the radial augmentation index.[21] That rapid onset makes N.O.V8™ a natural fit for pre-workout timing. The fermented lettuce and cabbage components broaden the nitrite pool beyond garlic alone, with fermented lettuce extract also shown to support a healthy inflammatory response in preclinical models.[22]

    At 20mg, the dose seems small by pre-workout standards, but remember that this is nitrate, not citrulline or nitrate, and the low dose required works perfectly in the capsule format. N.O.V8™ also pairs well with Shoden here: Shoden addresses the hormonal side of vascular health through cortisol regulation, while N.O.V8™ handles direct vasodilation through a complementary, enzyme-independent route.

  • Pyrroloquinoline Quinone (PQQ) - 20mg

    Bucked Up Flow

    Rounding it out, PQQ (pyrroloquinoline quinone) is a redox-active quinone that supports mitochondrial health by promoting mitochondrial biogenesis via PGC-1α activation and cycling through antioxidant reactions without degrading.[23][24] A 2023 study further demonstrated that PQQ drives ATP synthesis directly, increasing ATP content in neural tissue both in vitro and in vivo.[25]

    In human trials using 20mg daily, researchers measured increases in prefrontal cortex blood flow and oxygen metabolism alongside improvements in memory and cognitive flexibility.[26][27] Supplementation at that dose also decreased C-reactive protein and IL-6 in a crossover study, consistent with supporting a healthy inflammatory response in metabolically active tissue.[24]

    The 20mg dose in Flow matches the clinical standard. PQQ's cellular energy support and neuroprotective antioxidant activity layer naturally with the cognitive work L-theanine and Rhodiola do elsewhere in the formula.

How to Use Bucked Up Flow

Take two capsules daily with food and 6 to 8 oz of water. Flow has no stimulants, so timing is flexible. Pre-workout use stacks it cleanly with your performance ingredients. For the adaptogens (Shoden and Rhodiola) to deliver their full benefit, consistent daily use at a regular time is ideal, including on off days.

Stacks Well With

Arjuna Natural Logo

  • Bucked Up Pre-Workout or Bucked Up Black Ant: Flow contains no stimulants and no overlapping ingredients with Bucked Up's pre-workout line, so it layers cleanly regardless of which formula you're running.
  • On rest days: Take it at a consistent daily time on its own to keep the vascular and adaptogenic support working between training sessions.

Who It's For

  • Athletes who want to add stimulant-free pump support on top of their existing pre-workout
  • Anyone past 35 who wants NO support that doesn't rely on declining NOS enzyme activity
  • Cardiovascular health-conscious users looking for a daily formula combining adaptogens, antioxidants, and next-generation vasodilation in a clean two-capsule serving

Flow Fills a Real Gap, and Does it in New Ways

What a unique concept here.

Bucked Up Drive Hydration: Focused Hydration Built for the Long Game

50mg caffeine. Nootropics. Electrolytes. Zero sugar. Bucked Up Drive Hydration is a hydration RTD built with PGA Tour star Bryson DeChambeau for focus and fluid balance without the stim overload.

Bucked Up's pre-workout catalog is thorough, but a stim-free capsule for pure pump and circulation support has been missing. Flow answers it with an ingredient list that goes beyond the typical pump pill to cover HPA axis support, mitochondrial health, cognitive focus, and a genuinely new mechanism for nitric oxide delivery in N.O.V8™.

Shoden® holds it all together and brings the experience to new levels. At 35% withanolide glycosides in a 60mg dose, it's an ingredient that belongs in a formula like this, but is rarely ever used in that fashion. It's not a token adaptogen on a label but a meaningful contributor to the whole-body environment where vascular support works best. If you're new to it, start with our Shoden ingredient deep dive for the full context.

Between Flow and Bucked Up Drive Hydration, Bucked Up is building out a more complete cardiovascular performance stack across formats. Flow handles the stim-free capsule side of that equation. Check PricePlow for pricing and availability as it rolls out.

Bucked Up Flow – Deals and Price Drop Alerts

Get Price Alerts

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Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

Posts are sponsored in part by the retailers and/or brands listed on this page.

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About the Author: PricePlow Staff

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PricePlow is a team of supplement industry veterans that include medical students, competitive strength athletes, and scientific researchers who all became involved with dieting and supplements out of personal need.

The team's collective experiences and research target athletic performance and body composition goals, relying on low-toxicity meat-based diets.

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References

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  23. Yan, Tingdong, et al. "Pyrroloquinoline Quinone (PQQ): Its Impact on Human Health and Potential Benefits: PQQ: Human Health Impacts and Benefits." Current Research in Food Science, vol. 9, 22 Oct. 2024, p. 100889, doi:10.1016/j.crfs.2024.100889. https://pmc.ncbi.nlm.nih.gov/articles/PMC11541945/
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  27. Ikemoto, Kazuto, et al. "The Effects of Pyrroloquinoline Quinone Disodium Salt on Brain Function and Physiological Processes." The Journal of Medical Investigation, vol. 71, no. 1.2, 2024, pp. 23–28, doi:10.2152/jmi.71.23. https://pubmed.ncbi.nlm.nih.gov/38735721/

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