I Am Suprem3 Black Magic Pre Workout Takes the Reigns at Olympus Labs

Things have been crazy over at Olympus Labs in the fall of 2018!

Their recent launches of Superior Protein, the BloodShr3d Black Magic thermogenic fat burning powder, and estrogen-fighting Elim1nate have all brought interesting new ingredients to the market.

Olympus Labs I Am Suprem3 Black Magic

Were you a huge fan of RE1GN? Then we’ll save you some time: Olympus Labs I Am Suprem3 Black Magic edition is the same formula, only renamed and with improved flavor! But if you’ve never seen Re1gn, then buckle up, this formula is intense!

Today’s launch is a little bit different, because I Am Suprem3 Black Magic Edition is the same formula as the original Re1gn pre workout, just with a new name.

While Re1gn tubs will still be around for a while, the brand is using the name change to differentiate its products and versions:

What’s with the Olympus Labs Black Magic Products?

  • Black Magic Series supplements (like BloodShr3d Black Magic and I Am Suprem3 Black Magic) will have the “hardcore” stimulants like Re1gn did
  • The non Black Magic supplements will have internationally-compliant and Amazon-friendly ingredients such as Theacrine and Dynamine and no yohimbe

In this article, we are going to talk about I Am Suprem3 Black Magic Edition, but it’s really the same story as Re1gn — a crazy powerful pre workout (but with improved flavors here) that warrants an important disclaimer:

This pre workout does not contain yohimbe/yohimbine, but if you are sensitive to those ingredients then it’s recommended you start at a *very* light dose to assess strength. The Stimulant-X ingredient contains alkaloids similar to those from the yohimbe family.

With that disclaimed, let’s get ready to dive into one of the most hardcore formulas on the market, but first, let’s check prices and let you sign up for Olympus Labs news alerts:

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I Am Suprem3 Black Magic Ingredients

Note: The following doses come in two scoops. One scoop is suggested for beginners to assess tolerance.

  • L-Citrulline – 5g

    Olympus Labs I Am Suprem3 Ingredients

    Same as Re1gn, which we now realize was revolutionary when it launched! Due to placement on the bottle, gotta say this facts panel looks awesome

    Leading the Incredible Pump & Endurance Matrix (which is indeed incredible), Olympus Labs has a three-pronged pump attack starting with 5g of L-Citrulline, which is more than the entirety of many pre workouts on its own!

    Citrulline is the de-facto go-to nitric oxide booster, as it converts to arginine in the kidneys and that arginine then translates to more nitric oxide.[1] This induces a process known as vasodilation, where the blood vessels widen and blood flow increases. With that increase in blood flow, you get increase pumps, more nutrient and glucose delivery to the cells, performance enhancement, and reduced soreness!

    The performance enhancement gains often start at 3g citrulline,[2] but we have far more than that here. Note that some studies use citrulline malate, which is really just citrulline blended with malic acid in the supplement world. But don’t worry, I Am Suprem3 Black Magic does it proper by putting the malic acid in the other ingredients area of the label, so you have the best of both worlds here – a monster citrulline dose with the taste and texture benefits of the malic acid.

  • AGmass Agmatine Sulfate – 1g

    Agmatine Pathway

    The Agmatine Pathway is complex, but that’s because it’s really more of a neurotransmitter / neuromodulator than just a “nitric oxide booster”

    Citrulline was only the beginning. To keep those nitric oxide levels high, Olympus Labs added the popular nitric oxide extender in agmatine sulfate.

    We like to call agmatine more of an indirect NO booster since it prevents the breakdown of arginine by inhibiting the enzyme responsible for arginine’s breakdown, arginase.[3,4]

    This prolongs nitric oxide’s effects in the body, leading to longer and more “dense” pumps, as we’ve noticed. 500mg is usually a good starting point, and you get that in just one scoop of I Am Supreme Black Magic. Two scoops is where the magic starts to happen…

  • Pomegranate Powder Extract – 1g

    An incredibly healthy fruit in its own right, pomegranates and Pomegranate Extract provide several antioxidants that protect nitric oxide against oxidative destruction. Like agmatine (but in a far different manner), this results in a prolonged NO boost, which leads to longer performance gains and recovery capabilities.

    Research done in 2006 backed the theory and mechanism up with data,[5] so in 2014, it was put to the test at exactly this dose – 1g. Long story short? It worked![6]

    The researchers said it best themselves:

    Acute ingestion of Pomegranate Extract 30 min prior to exercise may enhance vessel diameter, blood flow, and delay fatigue during exercise. Results of the current study indicate that Pomegranate Extract is ergogenic for intermittent running, eliciting beneficial effects on blood flow.[6]

    We would expect to see it more often, but this is the kind of human-based research that Olympus Labs loves to find and put into action.

  • VASO-6

    Wow, was this brand ahead of the curve or what?! Re1gn was actually the initial launch of VASO-6, the epic six-constituent nitric oxide boosting ingredient extracted from green tea leaves!

    VASO-6 Vasodilation

    Charts like this always make us put our skeptical hat on, but after enough use, we’re believers!

    VASO-6™ goes beyond just an NO boost though, and also improves endurance and recovery through similar mechanisms as the ingredients discussed above.

    Initial studies noted that it yields endothelial-dependent relaxation (EDR) activity by 15% greater than placebo,[7,8] which could lead to even more epic vascularity and pumps on top of the ingredients above.

    On top of that, the compounds inside of VASO-6™ have been shown to increase blood flow[8], which then yielded enhanced glucose uptake and even muscle protein synthesis![9] Further, they could stimulate the endothelial nitric oxide synthase (eNOS) enzyme in order to also fight fatigue while improving recovery and perhaps even adding more strength![10,11,12,13]

    Re1gn was first to market with VASO-6, and now I Am Suprem3 carries the torch. Sometimes it’s awesome to revisit older articles about “new ingredients” and see what really took – this is definitely one of them!

    Olympus Labs’ original statements on VASO-6

    Olympus Labs even gave us some fantastic info about this ingredient right from the start, which we’re re-posting here:

    ”Vaso6 is a gallate-enhanced oligomer made up of dimers, trimers, tetramers and pentamers that is a powerful stimulator of nitric oxide production. It can be derived from the extracts of grape seed or green tea. Research has shown that extracts of grape seeds (GSE) causes endothelium dependent relaxation (EDR) activity in vitro. EDR activity involves the release of endothelial nitric oxide (NO) release and subsequent increase in cyclic guanosine monophosphate (GMP) levels in the vascular smooth muscle cells ultimately increasing vasodilation and blood flow.Isolation and characterization of GSE identified the extract was separated into seven fractions (A–G). Only fractions (D–G) were EDR-active so they were further separated into 25 individual compound peaks by high performance liquid chromatography (HPLC), 16 of which were EDR active. Analysis of these 16 peaks identified Procyanidin content, which are oligomeric compounds formed from catechin and epicatechin molecules. Peak G6, a trimeric procyanidin gallate, was identified as the peak that had the highest EDR activity. Vaso6 contains only the peaks and fractions of GSE with the highest EDR activity including peak G6, hence the name Vaso6.”

    –Olympus Labs

    Now it’s time to get into the stimulants!!

  • Caffeine – 300mg

    Olympus Labs

    Olympus Labs is back on PricePlow, and this is the kind of supplement we missed from them!

    In two scoops, 300mg is pretty much the “standard pre workout” dosage now. As the world’s most famous xanthine drug / supplement, this gets the engine started.

    But just because you can easily handle 300mg doesn’t mean you should jump right into a full two-scoop serving. Reason being, we still have three more stimulants at a very serious 378mg proprietary blend dosage.

    If you’re here, you should know what caffeine does for you. If you’re not a caffeine-user or aren’t familiar with its effects, hate to say it but Olympus Labs I Am Suprem3 Black Magic probably ain’t for you!

  • Eria Jarensis Extract

    The first of three ingredients in our 378mg mini-prop-blend, Eria Jarensis is often extracted for N-Phenethyldimethylamine, an “advanced” form of PEA.

    It’s also in the BloodShr3d Black Magic fat burner, and is a fast-acting, feel-good stimulant most often used to enhance mood and energy.[14] It works similarly to “regular” PEA, but due to it having two alkyl groups attached to its PEA backbone, it works a little bit longer in the system, since those alkyl groups prevent the monoamine oxidase (MAO) enzyme from breaking it down as quickly.

    You can compare PEA against the standard form of N-Phenethyldimethylamine below:

    PEA 2D Structure has no receptor protection

    The PEA molecule offers practically no physical protection for the amine (N), so MAO has no problem “cleaving” it into less relevant components. However….

    N-Phenethyldimethylamine 2D Receptor with Protection Highlighted

    N-Phenethyldimethylamine is like a PEA molecule, but with an N,N’ Alkyl section that also prevents MAO from cleaving it… meaning a longer-lasting euphoric ‘buzz’ than regular PEA

    This is the first of a two-pronged PEA-backboned attack to get dopamine going so that you’re amped up and ready to train hard. The second is next:

  • Juglans Regia Extract

    Olympus Labs Re1gn Supreme

    Remember, Olympus Labs was first to have J. Regia — and it was in Re1gn’s predecessor, Conqu3r Unleashed!

    If you’ll remember, Olympus Labs was the first company to bring Juglans Regia to dietary supplements (that was in the Conqu3r Unleashed pre workout, which has since been replaced by this formula). Also known as Persian walnut or English walnut, this is basically a walnut tree species found in Southwest China and the Himalayas. What’s interesting is that J. Regia contains several alkaloids,[15] but there’s one we’re most interested in.

    It’s often thought to be primarily extracted for 2-amino-5-methylheptane, which is the stronger (yet more expensive) form of “DMHA”.

    What we noticed from 2-amino-5 is that it’s far more euphoric than the regular 2-amino-6 form of DMHA, and seems to have a bit more zip and pop.

    Due to the proprietary blend here, we honestly don’t know how much we’re dealing with, but our best guess is that we have 250mg Eria Jarensis, 125mg Juglans Regia, and 3mg of this next beast:

  • STIM-X as C. Macroceras Extracted for Alkaloids

    Oh man, let’s do this but we gotta be real here. This is the ingredient where we got into a bit of a scuffle with Olympus Labs. We’re always excited for new ingredients, but we do need to have a serious disclaimer to those who are “Y-Sensitive” — This ingredient seems to be in the “yohimbe class” and caution is urged if you’re sensitive to yohimbe!

    Now on to some of our guesses as to what could be going on. Olympus Labs brought Stim-X to the market for RE1GN, it got a ton of attention, but they still won’t tell anyone what alkaloids have been extracted here!

    The full plant’s name is Coryanthe Macroceras, and the best guess is that it’s been standardized for something similar a yohimbine alkaloid of sorts, given the effects users get from it. But it’s not yohimbe, yohimbine, or even yohimbenine!

    Olympus Labs I Am Suprem3 Black Magic Benefits

    Get ready for it

    Macroceras definitely has some interesting alkaloids in it:

    • “False yohimbi bark, from C. macroceras, K. Schum, contains yohimbenine chiefly.”[16]
    • Yohimbine can also be found, as it’s listed in the “Normal” Yohimbine occurrences section on alkaloids.[17]
    • “A third yohimbi bark is derived from C. macroceras, which, however, contains but little of the active alkaloid yohimbine, and is therefor not so valuable as an aphrodisiac as the true drug, its chief constituent is the inactive yohimbenine.”[18]

    However, Olympus Labs has repeatedly stated that Re1gn does not contain yohimbine or yohimbenine.

    So what is it? The best we can do is shrug our shoulders at this point and consider it something similar, and if you’re like us and usually like these compounds, you should enjoy. But if you get anxious from them, then either start at a very light dose or pass until next time.

    Always a fun time researching these OL ingredients and herbs though. We’ll figure it out someday!

  • Tasteless TeaCrine – 100mg (yielding 40mg Theacrine)

    Not only was Olympus Labs first to launch VASO-6. Not only were the first to use Coryanthe Macroceras. Not only were they first to work with Juglans Regia…

    Teacrine

    Don’t forget, Olympus Labs brought Tasteless Teacrine to market!

    They were also first to use Tasteless Theacrine in the original Re1gn pre workout!

    This new-age xanthine compound provides long-lasting energy that seems to pair with whatever it’s paired with, but doesn’t have a tolerance build-up like caffeine does.[19]

    It’s a cool add-on, but the taste was downright terrible. Not anymore!!

    Olympus Labs was first to partner with Compound Solutions in developing “Tasteless Theacrine”, which comes at 40% of the weight but about 1% of the taste. It brings prolonged energy for hours on end, without the bitters!

  • KannaEase – 25mg (as Sceletium Tortuosum standardized for Alkaloids (Total Alkaloids ≥ 0.5%) & 0.2% Mesembrine)

    Also known as Kanna, Sceletium tortuosum works as a selective PDE-4 inhibitor, and thus increases cAMP levels, leading to an increase in energy.[20] In addition, the study cited above showed improved changes in mood and sleep! We really notice it in terms of improved mood!

    Superior Protein

    Olympus Labs’ Superior Protein nailed it, Velositol and all! With this one, the cereal bits are for real!

    On top of that, it is helpful when it comes to coping with stress and once again, sleep gets improved later on as well.[21]

    We usually feel the mood enhancement first and foremost, but Olympus Labs has possibly included it to help with performance if there is anything to be said with those cAMP levels. As you can guess from the trademarked name, KannaEase is marketing itself towards a reduction of anxiety, which is great given the high stimulant load in two scoops listed above!

    KannaEase is standardized to NLT 0.5% alkaloids and 0.2% mesembrine.

Same great formula, but now those new ingredients have been proven in a big way! But with that goes the same question – what are we really getting out of Stimulant-X here?!

Our old Re1gn Ingredient discussion still applies:

Don’t forget that Tim Muriello came on to PricePlow to discuss the Re1gn ingredients. You can still watch that video below!

Subscribe to PricePlow on YouTube

Flavors available at launch

Leave it to Olympus Labs to get creative with the flavor names, something they started with Re1gn as well (at least this time they tell us what to expect):

  • Olympus Labs I Am Suprem3 Black Magic Flavors

    I Am Suprem3 Black Magic launched at Natural Body Inc. with three flavors!

    Dark Magic (Black Cherry)
  • Lions Blood (Tropical Fusion)
  • Dragons Mist (Sour Blue Pop)

Not sure how sour to expect Dragon’s Mist to be, but when Olympus Labs does sour, they do it in a big way. Just watch the beginning of my review of BloodShr3d Black Magic, where I take down the Sucker Punch flavor. The DemiGods don’t mess around with flavor systems anymore!!

I am Supreme Black Magic reigns supreme in the hardcore pre workout space

If you want a non-DMAA, hardcore pre workout, this is about is intense as things are going to get right now. Re1gn was an epic launch that was a wild, wild ride for those who are Y-sensitive, so now that we have that disclaimer, we’re happy to recommend it to the right people – those who want to go all out and can handle everything listed above.

If it’s a bit too much or you’re in a country where you can’t get it, then you can check out our Olympus Labs page as there will be more news coming for you.

And if you miss the old flavors, see our original Re1gn post, which has those price comparisons. Otherwise, check out I Am Suprem3 Black Magic below and sign up for Olympus Labs news alerts, because this brand is busy:

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References

  1. Suzuki T, Morita M, Kobayashi Y, Kamimura A. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study. Journal of the International Society of Sports Nutrition. 2016;13:6; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759860/
  2. Sureda, A, et al; “L-citrulline-malate influence over branched chain amino acid utilization during exercise”; European Journal of Applied Physiology; 2010 Sep; 110(2):341-51 https://www.ncbi.nlm.nih.gov/pubmed/20499249
  3. Demady, D; “Agmatine Enhances the NADPH Oxidase Activity of Neuronal NO Synthase and Leads to Oxidative Inactivation of the Enzyme”; Molecular Pharmacology; January 2001, 59(1) 24-29; http://molpharm.aspetjournals.org/content/59/1/24.long
  4. Galea, E, “Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine”; Biochemical Journal May 15, 1996, 316 (1) 247-249; http://www.biochemj.org/content/316/1/247
  5. Ignarro, L, et al; “Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide”; Nitric Oxide; 2006; Sep; 15(2):93-102; https://www.ncbi.nlm.nih.gov/pubmed/16626982
  6. Trexler, Eric T et al; “Effects of pomegranate extract on blood flow and running time to exhaustion”; Applied physiology, nutrition, and metabolism; 39,9 (2014): 1038-42; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146683/
  7. Fitzpatrick DF, Fleming C, Bing B, Maggi DA, Malley MO; “Isolation and Characterization of Endothelium – Dependent Vaso relaxing Compounds from Grape Seeds”; J Agric Food Chem. 2000; 204:6384-6390; https://www.ncbi.nlm.nih.gov/pubmed/11312812
  8. Lorenz M, Wessler S, Follmann E, et al; “A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation”; J Biol Chem; 2004; 279(7):6190-6195; http://www.jbc.org/content/279/7/6190.full.pdf+html
  9. Kim JA, Formoso G, Li Y, et al; “Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn”; J Biol Chem. 2007; 282(18):13736-13745; http://www.jbc.org/content/282/18/13736.full.pdf+html
  10. Nogueira L, Ramirez-Sanchez I, Perkins GA, et al; “(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle”; J Physiol. 2011; 589(Pt 18):4615-4631; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208228/
  11. Myburgh KH, Kruger MJ, Smith C; “Accelerated skeletal muscle recovery after in vivo polyphenol administration”; J Nutr Biochem; 2012; 23(9):1072-1079; https://www.ncbi.nlm.nih.gov/pubmed/22079208
  12. Lee S, Leem Y, Go G, et al; “Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts”; 2017:1-14; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175271
  13. Kruger MJ, Smith C; “Postcontusion polyphenol treatment alters inflammation and muscle regeneration”; Med Sci Sports Exerc. 2012; 44(5):872-880; https://insights.ovid.com/crossref?an=00005768-201205000-00014
  14. Mesfioui, A., Math, F., Jmari, K., Hessni, A. E., Choulli, M. K., & Davrainville, J; “Effects of Amphetamine and Phenylethylamine on Catecholamine Release in the Glomerular Layer of the Rat Olfactory Bulb”; Neurosignals; 1998; 7(4), 235-243; https://www.karger.com/Article/Abstract/14548
  15. Ismet, Ara, et al; “Evaluation of Antimicrobial Properties of Two Different Extracts of Juglans regia Tree Bark and Search for Their Compounds Using Gas Chromatography-Mass Spectrum”; International Journal of Biology; Vol. 5, No. 2; 2013; Retrieved from http://www.ccsenet.org/journal/index.php/ijb/article/view/25651/15862
  16. “British Pharmaceutical Codex”; 1907; books.google.com
  17. R. H. F. Manske; “The Alkaloids: Chemistry and Physiology”; Elsevier; May 12, 2014; books.google.com
  18. Braithwaite, J.O.; “Year Book of Pharmacy”; 1908; books.google.com
  19. Cauli, O; “Subchronic caffeine exposure induces sensitization to caffeine and cross-sensitization to amphetamine ipsilateral turning behavior independent from dopamine release”; Department of Toxicology and Centre of Excellence for Neurobiology of Dependence, University of Cagliari; 2008; http://www.ncbi.nlm.nih.gov/pubmed/12865902
  20. Chiu, Simon et al; “Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium Tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia”; Evidence-based Complementary and Alternative Medicine: eCAM; 2014; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217361/
  21. Nell, Haylene, et al; “A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial of Extract Sceletium tortuosum (Zembrin) in Healthy Adults”; The Journal of Alternative and Complementary Medicine; Volume 19, Number 11, 2013, pp. 898-904; http://online.liebertpub.com/doi/pdf/10.1089/acm.2012.0185
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