We live in an age of utter abundance when it comes to well-dosed pre workouts. The era of the “concentrated” micro-dosed pre workout reign is long gone, and pre workouts of today are a considerable step up in quality, scoop size, and overall effects.
One such company utilizing these mega-sized pre workouts is Muscle Building Nutrition, where we introduced them here in towards the end of 2016. In that post, we documented their commitment to fully-dosed, research-backed formulations – so now it’s time to find out how serious they are.
Today, we feature the brand’s flagship supplement in Dominate — a clinically dosed pre workout that will have you dominating in the gym like never before.
Before we get to the breakdown, you can get DOMINATE through their site Muscle-Building-Nutrition.com. If you want to check if it’s available on Amazon or any other stores, see below and sign up for alerts:
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Dominate packs a massive 28g per scoop (that’s like the size of a protein powder scoop!) and there are A LOT of actives here, all clinically dosed. One single scoop contains everything you’ll need to maximize your time in the gym and make some serious gains!
Citrulline Malate 2:1 (6g)
How about a nice hefty 6g dose of Citrulline Malate to get things rolling?!
This potent nitric oxide booster surpasses L-Arginine due to its superior bioavailability in the body, resulting in significantly greater N.O. production, vasodilation, and best of all, PUMPS!
CitMal offers plenty more than just swole guns though, it’s also a powerful ergogenic. Clinical trials demonstrate that it also boosts endurance, enhances ATP production, reduces fatigue, and improves lean body mass.[2,3,4]
This is how you start off a dominating pre workout!
Intense exercise is an incredibly catabolic (muscle-wasting) process. To ward off muscle breakdown during your workouts, it’s imperative to consume some form of amino acids before or during training. Lucky for you, MBN has included a monstrous 6g dose of 2:1:1 BCAAs! This dose is even greater than some BCAA-only supplements offer!
Each scoop packs 3g Leucine and 1.5g each of Isoleucine and Valine. Leucine is the primary stimulator of mTOR pathway in the body, responsible for driving muscle protein synthesis, and ultimately keeping you anabolic. Additionally, the 6g of BCAAs will kickstart the recovery process and combat DOMS[6,7] so you can keep coming back for more day after day.
Creapure® Creatine Monohydrate (5g)
Often times, companies resort to the more trendy forms of creatine, such as Creatine HCl or Magnesium Creatine Chelate (MCC); however, none have the research backing it quite like creatine monohydrate. For this reason, MBN has included the gold standard form of creatine so you can rest assured you’re getting all the benefits possible from this age-old muscle builder.
Creatine is well established in the world of athletics as an ergogenic. It enhances just about every aspect of athletic performance, from strength to power to growth.[8,9,10] Dominate contains a full 5g dose of the purest form of monohydrate in Creapure to make sure you get nothing but the best!
This ain’t no 3g dose either. While that’s the minimum clinical dose, those of us who’ve been in the game love to keep it real at the 5g dose that has even more research behind it. Yeah it adds bulk to the powder, but it’s welcomed bulk – Muscle Building Nutrition lives up to its name.
CarnoSyn® Beta Alanine (3.2g)
Ready for some serious tingles?!
Dominate’s next fully dosed ergogenic is the tingle-inducing endurance booster Beta Alanine. Once ingested, beta alanine binds to histidine in the muscle and forms carnosine, a mighty intracellular buffer. Carnosine helps prevent lactic acid buildup, which offsets the burn, enabling you to workout longer before succumbing to fatigue.
Beta alanine also improves power, strength, endurance, and time to exhaustion.[12,13,14] Just be warned, that if you’re not used to taking the full dose of BA all at once, you may be inline for a nasty bout of paresthesia (“tingles”).
At 3.2g, this is the clinical dose – which often gets spread out throughout the day, but here you’re knocking it down all at once.
Betaine Anhydrous (2.5g)
Betaine Anhydrous, also known as trimethylglycine or TMG, is yet another proven muscle build included in Dominate. Betaine is naturally occurring in sugar beets and has been documented over and over to amplify power, strength, and endurance.[15,16,17]
Furthermore, betaine helps reduce soreness and has even been linked to enhancing creatine production in the body. We’ve got plenty more info on this ergogenic, and you can see it all in our betaine mega-post.
Again, just like creatine, you get the full dose – that brings you to 7.5g of muscle-building ergogenics! Take this and you are done with your creatine and betaine needs for the day.
L-Tyrosine is an amino acid commonly used in pre workouts to improve focus and cognition. Tyrosine increases the production of two big neurotransmitters, noradrenaline and dopamine, which, in addition to heightening focus, also lowers stress and anxiety.[18,19]
This may be the one ingredient that is a bit on the lower side, but coupled with the next two stims, you should still feel a strong boost in focus when using Dominate.
Caffeine Anhydrous (200mg)
Muscle-builders out of the way, it’s now time to turn things up a notch with our next two ingredients. Our first stimulant is the granddaddy of all stimulants, caffeine anhydrous. Dominate includes an extremely appropriate amount of caffeine at 200mg per serving.
We’re seeing a bit of a comeback with the ~200mg caffeine doses, as shown on our top 10 pre workout supplements list. This is just enough to get you going without inducing a bunch of jitters or setting you up for a nasty crash.
But there’s another trick up Muscle Building Nutrition’s sleeve: Paired with our next stimulant, this 200mg will hit a bit stronger, last longer, and simply feel a whole lot better:
Theacrine is another xanthine-like compound similar to caffeine that offers many of the same stimulatory effects as its more well-known counterpart. Teacrine® is a trademarked ingredient that contains 98% concentrated theacrine.
The difference between theacrine and caffeine is that theacrine doesn’t come with caffeine’s nasty tolerance build up, which means you won’t need to continually “up the dose” to experience the same energized feelings. Furthermore, various clinical trials note that when used for at least seven days straight, theacrine reduces oxidative stress, and boosts dopamine levels, similar to caffeine.
The 100mg dose is the real key here. Other pre workouts include 25 to 50mg of theacrine, and aren’t really noticeable. Including 100mg is a considerable step up and you’ll most certainly feel theacrine’s long lasting energy boost here.
Now here’s the question – how will MBN Dominate taste?! Because the honest truth is that Teacrine is one of the worst-tasting stimulants on the market, and it takes some serious work to flavor on top of 100mg.
But for us experienced users, we don’t even care, because this dose seems to be where it’s at, and we fully expect the energy profile here to kick ass, even with just 200mg caffeine!
Dominate is currently only available in Blue Raspberry, so hopefully you’re a fan of this flavor. We do anticipate MBN expanding the flavor line up in the coming months though.
Muscle-Building Nutrition may only have one product currently in its lineup, but it sure is a workhorse of a pre workout! Dominate provides all of the daily essentials for muscle-building plus full doses of several ingredients that provide immediate benefit during your workout. The end result is pure domination of the weights and more gains for you!
MBN has more products in the the pipeline and if Dominate is any indication of what’s in store, we’re very excited about what’s next!
You can get DOMINATE through their site Muscle-Building-Nutrition.com. If you want to check if it’s available on Amazon or any other stores, see below and sign up for alerts:
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- Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
- Wilson GJ1, Layman DK, Moulton CJ, Norton LE, Anthony TG, Proud CG, Rupassara SI, Garlick PJ. Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats. Am J Physiol Endocrinol Metab. 2011 Dec;301(6):E1236-42
- Bailey SJ, Blackwell JR, Lord T, Vanhatalo A, Winyard PG, Jones AM. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans. J Appl Physiol (1985). 2015 Aug 15;119(4):385-95
- Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010 May;24(5):1215-22.
- Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr. 2006 Feb;136(2):533S-537S.
- Blomstrand E, Eliasson J, Karlsson HK, Köhnke R; Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise. J Nutr. 2006 Jan;136(1 Suppl):269S-73S
- Howatson G, Hoad M, Goodall S, Tallent J, Bell PG, French DN. Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study. J Int Soc Sports Nutr. 2012 Jul 12;9:20.
- Netreba, A; [Creatine as a metabolic controller of skeletal muscles structure and function in strength exercises in humans].; Ross Fiziol; 2006
- Bemben, M; The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.; Neuromuscular Lab, Dept. Health & Exercise Science, U. Oklahoma; 2010
- Chilibeck, P; Effect of creatine ingestion after exercise on muscle thickness in males and females.; College of Kinesiology, University of Saskatchewan; 2004
- Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
- Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training“
- Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
- Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
- Lee EC, et al. Ergogenic effects of betaine supplementation on strength and power performance. J Int Soc Sports Nutr. (2010)
- holewa, J; Effects of betaine on body composition, performance, and homocysteine thiolactone.; Department of Kinesiology, Recreation, and Sport Studies, Coastal Carolina University; 2013
- Effect of betaine supplementation on power performance and fatigue
- Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
- Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
- Cauli, O;Subchronic caffeine exposure induces sensitization to caffeine and cross-sensitization to amphetamine ipsilateral turning behavior independent from dopamine release.; Department of Toxicology and Centre of Excellence for Neurobiology of Dependence, University of Cagliari; 2008
- Li WX, et al.; “Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice.“; J Agric Food Chem.; 2013
- Feduccia A, et al.; “Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.”; Pharmacol Biochem Behav; 2012