Primeval Labs Vasogorge — Engorge Your Veins!

Primeval Labs Vasogorge

Primeval Labs Vasogorge is a stimulant free, nitric oxide enhancing supplement boosting pumps from every conceivable angle.

Primeval Labs has been one of the biggest movers and shakers in the supplement industry this year, and shows no sign of slowing down. Since the outset of 2017, they’ve continually been in the headlines whether it be with the release of a new product, or the acquisition of another brand (such as the BPS Nutrition takeover). Again, we find ourselves covering the brand, and this time it’s for one of their non-stim products.

Vasogorge is a stimulant-free, nitric oxide / cellular swelling pump pre workout that can be used on its own, or stacked with Primeval Labs stim-based pre workouts Ape Shit or Adrenal Rush V2 for maximum energy and pumps.

Note that this is a pre workout capsule product, which is good for those who don’t want the fuss or extra “inactive ingredients” that come with powders.

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Vasogorge Ingredients

Vasogorge enhances your pumps from every conceivable direction by stimulating the arginine and nitrate-nitrite pathways as well as increasings cellular swelling with the inclusion of HydroMax, which is where we’ll begin this ingredient breakdown.

  • HydroMax 65% (1,500mg)

    Primeval Labs Vasogorge Ingredients

    Vasogorge includes a straightforward collection of proven N.O. boosters to give you some truly epic pumps.

    HydroMax is the leading form of glycerol used in pre workouts these days. Compared to glycerol monostearate (GMS) which contains 25% glycerol at most, HydroMax contains 65% by weight, giving you significantly more glycerol per serving.

    Glycerol super soaks your muscles with water by transforming them into super-absorbent sponges. This additional water not only enhances intracellular hydration, but also aids endurance and helps prevent cramping and fatigue.[1,2]

  • Arginine AKG (750mg)

    Arginine was once the king of nitric oxide boosting compounds, that is until research showed it isn’t very effective due to poor bioavailability.[3] That gave birth to alternative forms of Arginine being created, including the anionic salt of arginine alpha-ketoglutarate (AAKG).

    This optimized form of arginine was believed to enhance the bioavailability and effectiveness of arginine in the body, helping it survive the stomach and enhance uptake in the intestines. Research is mixed at best, as some studies shows it increases plasma arginine levels, but other studies show it has no effect, or possibly decreases performance.[4,5,6]

    Our take is that this is an “ok” add-on pump booster, as part of a bigger formula, but it shouldn’t be the main NO-boosting compound in a pump pre workout given that its effectiveness is highly questionable.

    Good with nitrates!

    We do like seeing it next to nitrates, which is what we’ll get with the beet root powder. This is because arginine reduces the tolerance to nitrate,[11] an effect that could be more important for running this tub than the arginine itself!

  • Agmatine (750mg)

    Primeval Labs Vasogorge Pumped

    Want pumps but not the stims of other pre workouts? Vasogorge has you covered.

    Agmatine is one of our favorite NO-boosting compounds. Rather than directly boost nitric oxide production in the body, agmatine indirectly boosts it by inhibiting the enzyme that prohibits nitric oxide production, arginase.[7]

    With arginase out of the picture, your body is free to keep NO synthesis cranking full steam ahead, resulting in massive muscle pumps. Combined with the brands best-selling Adrenal Rush V2 pre workout, you’ll get 2.25g of Agmatine, making for some incredibly long-lasting pumps! Maybe even painful pumps – and in the good way!

  • Beet Root Powder (250mg)

    Similar to agmatine, beet root is another great “supporting” nitric oxide booster. It’s rich in nitrates[8], which stimulates nitric oxide production via a different pathway than citrulline/arginine/agmatine does.

    Nitrates are awesome, and not just for their NO-boosting potential. They’re also valuable performance enhancers as they increase blood flow, improve VO2 max, and reduce the oxygen cost of exercise, thereby making your body more efficient.[9,10]

    We’re big fans of beet root, but it will depend on how strong the extract truly is, and if it’s been standardized for enough nitrates. Thankfully, we also have the arginine to pair with it. Only one way to find out… subscribe to our YouTube channel to get the review when we have it in!

Dosing

Primeval Labs Vasogorge Stack

Stack Vasogorge with EAA Max, Adrenal Rush V2, and Tri-Andro for the ultimate mass-gaining stack.

Consume 5 capsules 15-20 minutes prior to training.

Takeaway

Vasogorge isn’t the same old pump pre workout supplement you’re used to seeing. It’s always handy to have a few extra pump pills hanging around, and while we’re not huge fans of arginine alone, we do love it with the nitrates from beetroot.

Combined with either of Primeval’s top-notch pre workouts, you’ll be in for some of the biggest, and longest-lasting, muscle pumps you’ve ever experienced – especially if you dig the agmatine!!

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References

  1. van Rosendal, S; Guidelines for glycerol use in hyperhydration and rehydration associated with exercise.; School of Human Movement Studies, The University of Queensland; 2010
  2. Wingo, J; Influence of a Pre-Exercise Glycerol Hydration Beverage on Performance and Physiologic Function During Mountain-Bike Races in the Heat; University of Connecticut, Department of Sport, Leisure, & Exercise Science; 2004
  3. Tangphao O, Grossmann M, Chalon S, Hoffman BB, Blaschke TF. Pharmacokinetics of intravenous and oral l-arginine in normal volunteers. British Journal of Clinical Pharmacology. 1999;47(3):261-266. doi:10.1046/j.1365-2125.1999.00883.x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014227/
  4. Willoughby DS, Boucher T, Reid J, Skelton G, Clark M. Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow,  plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. Int J Sport Nutr Exerc Metab. 2011;21(4):291-299. https://www.ncbi.nlm.nih.gov/pubmed/21813912
  5. Wax B, Kavazis AN, Webb HE, Brown SP. Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. Journal of the International Society of Sports Nutrition. 2012;9:17. doi:10.1186/1550-2783-9-17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428651/
  6. Greer, BK; BT Jones (Jul 2011). “Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training”. Journal of Strength and Conditioning Research. 25 (7): 1789–94. PMID 21399536. doi:10.1519/JSC.0b013e3181e07569. https://www.ncbi.nlm.nih.gov/pubmed/21399536
  7. Demady, D; Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme.; Department of Pharmacology, The University of Michigan Medical School; 2001
  8. Palmer RM, Ashton DS, Moncada S Vascular endothelial cells synthesize nitric oxide from L-arginine . Nature. (1988)
  9. Cosby K, et al; Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation . Nat Med. (2003)
  10. Modin A, et al; Nitrite-derived nitric oxide: a possible mediator of ‘acidic-metabolic’ vasodilation . Acta Physiol Scand. (2001)
  11. MacAllister, Raymond J. “Arginine and Nitrate Tolerance.” British Journal of Pharmacology 130.2 (2000): 209–210; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572089/
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