Engorge Yourself with Primeval Labs VasoGorge

VasoGorge Get Ready For Pre-Workout Pumps

Get ready for massive Nitrosigine-based pumps!

Bodybuilders and athletes have been known to chase the “pump,” the maximization of blood flow to muscles during and after a workout. At times, our enthusiasm for The Pump has seemingly verged on ridiculous, but there’s a very good reason for it: a bigger pump is better across the board.

Today we’re talking about VasoGorge, a powerful and elegant supplement from Primeval Labs that’s formulated to pump you up to the max.

VasoGorge is back, and this time it’s bringing Nitrosigine

VasoGorge is designed around Nitrosigine, a designer form of arginine from one of our favorite industry innovators, Nutrition21.

Watching Primeval Labs team up with Nutrition21 is a sight to see, since both companies always coming up with something new — combining patented and tested ingredients with Primeval’s formulation expertise means you’re going to get something powerful. When we first heard about Nitrosigine a few years ago, the science was very promising, and it’s only gotten better as more data’s been released.

It’s all covered below, but if you want to read more about Primeval Labs’ transformative work, see our Primeval Labs news page, check PricePlow’s coupon-powered prices below, and get ready to get pumped:

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Ingredients

VasoGorge Product Ingredients Label

Get GORGED on nitric oxide

In a five-capsule dose of VasoGorge, you get the following:

  • Inositol-Stabilized Arginine Silicate (as Nitrosigine) – 1500 mg

    The primary target for anyone looking to increase their pump is the nitric oxide system. Nitric oxide (NO) is the molecule that causes smooth muscle surrounding your blood vessels to relax, leading to vasodilation. It’s a common phenomenon where your veins and arteries grow in diameter.[1] This, in turn, improves blood circulation, especially through small capillaries and veins. When your circulation is better, it improves fuel and nutrient delivery to cells.[2] That means better performance during a workout, and faster, more effective recovery after a workout. It means lower blood pressure, and less strain on your heart and blood vessels as you push yourself to your limit.

    Primeval Labs VasoGorge Vasodilation

    A blood vessel before (L) and after (R) undergoing vasodilation

    Maximizing nitric oxide production is key to achieving an awesome pump. Back in the day, people tried to achieve this with arginine supplementation, but it proved to be largely ineffective. That’s because when arginine is ingested, it is broken down in the gut by the “first pass” effect, meaning that very little of it actually makes it into the bloodstream where it can be biologically active.[3] Put simply, the bioavailability of arginine is low.[3]

    That’s where Nitrosigine from Nutrition 21 comes in. Nutrition 21 solved the problem of low arginine bioavailability by synthesizing a stabilized form of arginine called Nitrosigine.

    Introducing Nitrosigine: A better arginine

    Nitrosigine Benefits

    Nitrosigine is research-backed and “gym backed” — Image courtesy Nutrition21

    Nitrosigine is a complex of arginine, inositol, and potassium silicate.[4] When bonded with these other two molecules, arginine becomes significantly more bioavailable compared to regular arginine.[5] Moreover, the complex of these three molecules outperforms the combination of the individual ingredients in equivalent doses,[5] suggesting that the arginine part of the complex is somehow protected from breaking down thanks to its chemical bonds with inositol and potassium silicate. It probably does this by inhibiting arginase, the enzyme responsible for breaking down arginine in the gut.[6]

    This makes for an arginine supplement that’s both fast-acting and long-lasting: research on the effects of Nitrosigine has shown that it is biologically active half an hour after ingestion, with the duration of the effect being somewhere between 1.5 hours and 6 hours.[7,8]

    One of the many amazing things about the arginine-inositol-potassium silicate complex (ASI) is that it has benefits beyond physical performance. This compound has been shown in a research setting to improve cognition across multiple domains in athletes,[9] preventing the temporary cognitive decline that follows intense exercise, and enabling users to complete cognitive tests faster compared to those who did not receive Nitrosigine.

    And if you’re not an athlete, take note anyways: in young men who weren’t acutely fatigued from exercise, Nitrosigine improved the speed of task switching, which is a measure of cognitive flexibility.[10]

    If you’re looking for a good sound bite to sum up the benefits of Nitrosigine, here it is: subjects who were given 1,500 milligrams of Nitrosigine daily experienced increased perceived energy after 72 hours of supplementation.[7] Feeling energetic is fundamental to accomplishing any task, mental or physical. And these results aren’t surprising, considering how fundamental blood flow is to the body’s energy supply.

    If you want an even longer, more in-depth discussion of what makes Nitrosigine so awesome, check out our long-form article on the subject, Nitrosigine: The Nitric Oxide Booster That Enhances Brain Function.”

  • Pine Bark Extract (Pinus massoniana) – 250 mg

    Primeval Labs ApeSht Untamed RTD

    When Primeval Labs enters a niche, they enter explosively. Get ready to go Ape – no shaker cup needed. Stack it with VasoGorge!

    Just like Nitrosigine, pine bark extract increases vasodilation by escalating the nitric oxide (NO) production of the body. Chock full of antioxidant phenolic compounds,[11,12] pine bark extract stimulates endothelial nitric oxide synthase, also known as eNOS,[11,12] the enzyme responsible for creating nitric oxide. Theoretically, activating eNOS should result in greater nitric oxide production.

    Partly because of its effect on NO production, partly because of its inherent antioxidant properties, pine bark extract has been used for many years as an herbal treatment for various diseases of the cardiovascular system,[11,12] on which it has been shown to have broad protective effects.[11,12]

    It has been suggested by limited research that pine bark extract can help prevent chronic inflammation and neurological problems.[12]

  • Pink Himalayan Salt – 250 mg

    You might be surprised to see salt here, since sodium intake is typically associated with vasoconstriction and higher blood pressure. But that’s no concern, because the amount of sodium included here is minuscule — the idea behind including pink Himalayan salt is that this particular salt contains magnesium, potassium, and calcium in addition to sodium, making it the perfect ingredient for comprehensive electrolyte support.

    primeval-labs-vasogorge-himalayan-pink-salt

    Himalayan pink salt in its coarse form

    Electrolyte support is important because ultimately, the point of a pump is to help us work out harder. And if your muscles don’t have enough of these crucial electrolyte minerals, they will function below their optimal capacity.

    Sodium in particular, despite its bad rap, is needed for muscles to contract.[13] If you’re working-out hard, you should always be sure to replace the sodium your body inevitably loses through sweat. Otherwise, your performance and recovery will be impaired.[14] If you’re feeling like your performance has been subpar lately, adding more salt to your diet is one of the first easy fixes you should try.

    If you’re interested in learning more about sodium supplementation, check out our long-form reference on the subject, “The Importance of Salt in the Athlete’s Diet”[14].

Conclusion

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The most effective supplements often have the simplest and most elegant formulas, and that’s exactly what we have with VasoGorge. Nitrosigine is doing the heavy lifting here, which is fine because it’s a powerful ingredient, one of the absolute best and most direct methods to raise blood arginine levels that we know of.

Pine pollen is a very smart choice to stack with Nitrosigine — a perfect synergy since Nitrosigine provides raw materials for the production of nitric oxide while pine pollen stimulates the synthesis of those raw materials into nitric oxide.

Given the unbelievable importance of nitric oxide for whole-body fitness, we recommend this supplement for anyone who’s active, or just wants to improve their cardiovascular health.

Primeval Labs Vasogorge – Deals and Price Drop Alerts

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Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Nick Andrews

Nick Andrews
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References

  1. Schwedhelm, Edzard et al.; “Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.”; British journal of clinical pharmacology vol. 65,1 (2008): 51-9.; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291275/
  2. Vijaya Juturu V., Komorowski, JR. 2002. US7576132B2 – “Arginine Silicate Inositol Complex and use Thereof.” The United States Patent and Trademark Office. https://patents.google.com/patent/US7576132
  3. Sandler, D., et al. June 2016. “Absorption of Bonded Arginine Silicate Compared to Individual Arginine and Silicon Components.” Journal of the International Society of Sports Nutrition vol. 13. https://jissn.biomedcentral.com/articles/10.1186/s12970-016-0144-9
  4. Rood-Ojalvo, S. et al. Sep. 2015. “The Benefits of Inositol-Stabilized Arginine Silicate as a Workout Ingredient.” Journal of the International Society of Sports Nutrition vol. 12(S1). https://jissn.biomedcentral.com/articles/10.1186/1550-2783-12-S1-P14
  5. Kalman, D. et al. June 2018. “An Evaluation of the Effects of Inositol-Stabilized Arginine Silicate (ASI; Nitrosigine) On Cognitive Flexibility.” Nutrients https://blog.priceplow.com/wp-content/uploads/nitrosigine-cognitive-flexibility-issn-2018.pdf
  6. Helms CC, Gladwin MT and Kim-Shapiro DB (2018) Erythrocytes and Vascular Function: Oxygen and Nitric Oxide. Front. Physiol. 9:125. doi: 10.3389/fphys.2018.00125 https://www.frontiersin.org/articles/10.3389/fphys.2018.00125/full
  7. Stryer, Lubert (1995). Biochemistry, 4th Edition. W.H. Freeman and Company. p. 732
  8. Evans, M., et al., June 2018. “An Evaluation of the Effects of Inositol-Stabilized Arginine Silicate (ASI; Nitrosigine) in Preventing the Decline of Cognitive Function Caused by Strenuous Exercise.” International Society of Sports Nutrition 2018 Conference. https://blog.priceplow.com/wp-content/uploads/nitrosigine-preventing-cognitive-decline-caused-by-strenuous-exercise.pdf
  9. Kalman, D., Hewlings, S., Sylla, S., Ojalvo, S., & Komorrowski, J; “An evaluation of the effects of inositol-stabilized arginine silicate (ASI; Nitrosigine) on cognitive flexibility”; Nutrients; 2016; https://blog.priceplow.com/wp-content/uploads/nitrosigine-cognitive-flexibility-issn-2018.pdf
  10. Komorowski, J., Perez, S., & Sylla, S; “Arginase Inhibition by Inositol-stabilized Arginine Silicate (ASI; Nitrosigine); A Novel Mechanism by which ASI Enhances Arginine Bioavailability”; Poster Presentation. Retrieved from https://www.eventscribe.com/2018/Nutrition2018/ajaxcalls/PosterInfo.asp?efp=UlhTRFpZVVI0ODYw&PosterID=146640&rnd=0.1401379
  11. Iravani, S. et al. June 2011. “Pharmaceutical and Nutraceutical Effects of Pinus Pinaster Bark Extract.” Research in Pharmaceutical Sciences vol. 6,1; 1-11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203267/
  12. Li, Y. et al. Apr. 2015. “Pine Bark Extracts: Nutraceutical, Pharmacological, and Toxicological Evaluation.” The Journal of Pharmacology and Experimental Therapeutics vol. 353,1; 9–16. https://pubmed.ncbi.nlm.nih.gov/25597308/
  13. Strazzullo P., Leclercq C.; “Sodium.” Advanced Nutrition; March 2014; 5(2) 188-190; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951800/
  14. Valentine, V. 2007. “The Importance of Salt in the Athlete’s Diet.” Current Sports Medicine Reports vol. 6,4 (2007): 237-40. https://pubmed.ncbi.nlm.nih.gov/17617999/

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