PEScience Alphamine: The Athlete’s Energy Drink Reformulated for 2020

Since 2012, Alphamine has been a fan favorite energy drink powder to many. As the times and the industry changes, so do formulas. The newest version of Alphamine brings a few tweaks to improve its formula and widen its distribution and appeal to more consumers, while still maintaining itself as the best value cost per serving powder on the market (that 60 serving tub is dense!).

Alphamine PricePlow

Alphamine, the Athlete’s Energy Drink, is now sporting a new formula!

The 2020 Alphamine Formula Changes

The most notable change in the new Alphamine formula is the removal of L-Leucine and ferulic acid in order to add more choline and l-carnitine. PEScience also added in L-Ornithine, an amino acid that plays a role in the urea cycle. This new formula is upgraded to give you a greater boost in energy, along with more fatty acid oxidation.

The Athlete’s Energy Drink

Alphamine is an extremely versatile energy supplement, since its formula is simple, straightforward, and just feels good. You can use Alphamine to replace your morning coffee, as an afternoon pick me up, or even as a pre workout supplement. If you use it before training, we recommend adding in a serving or two of High Volume, PEScience’s non stim pump product!

No matter how you use it, Alphamine is a very affordable way to boost your energy, focus, and metabolism. If you’re used to paying $3-$5 dollars on an overpriced coffee or energy drink, make the switch to Alphamine to not only save money, but get extra benefits from all of the other ingredients it has to offer!

Before we get to the new label, take a moment to sign up for alerts from PricePlow and check our coupon-driven deals:

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Note: The formula discussed below is for the 60 serving tubs listed above.

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Alphamine 2020 vs. 2016 Label Comparison

Before getting into the research and synergy behind each ingredient, let’s first compare the formula changes, with the new 2020 formula on the left:

PEScience Alphamine Ingredients 2020

The New 2020 Alphamine Formula

Alphamine 2016 Formula

The old 2016 formula

Alphamine Ingredient Analysis

The new formula still features a proprietary blend, so we don’t know the exact dosages of each ingredient, however the 125mg of caffeine has still remained the same!

Here’s what one serving (2.9g) of Alphamine provides:

Alphamine Proprietary Blend (1,600mg)

  • Choline Bitartrate

    Alphamine Ingredients Updated

    Here’s a look at Alphamine’s new formula for 2020!

    More choline for more focus and fat burning support!

    Choline is a part of the B-vitamin complex and required for optimal body function. However, it’s one of the more difficult vitamins to consume in adequate amounts since it’s only present in significant quantities in a few specific foods such as eggs, chicken, and broccoli.[1]

    Choline helps mobilize fat and suppress appetite, but it really shines as a nootropic. It’s a powerful focus enhancer that supports and strengthens the neural communication pathways.[2,3]

    Specifically, choline increases the production of acetylcholine, the neurotransmitter that carries commands between the central nervous system and the skeletal muscle system.[4] This helps foster a stronger “mind-muscle” connection which is necessary if you want to reap as much benefit as possible from your workouts.

    Syenrgy with carnitine!

    As for its purpose in this formula, at doses achievable with 2 scoops if Alphamine meets the claims for a 2003 study done on women, showing the combination of choline and LCLT helps to mobilize (break down) fat.[5] Several studies have concluded that choline helps increase carnitine retention, resulting in a prolonged elevation in carnitine levels.[6-9]

    As you’ll see in the L-carnitine L-Tartrate section below, carnitine is crucial for fatty acid oxidation since it acts as a transporter for fatty acids to enter the mitochondria. Choline, carnitine, and caffeine are the triple threat for maximal thermogenesis.

  • L-Carnitine L-Tartrate

    L-Carnitine supplements have been around for years and years, and used by many. L-Carnitine L-Tartrate (LCLT) is a more bioavailable of the amino acid L-Carnitine.

    PEScience Alphamine Tropical Twist 2020

    Be swept away on a tropical paradise with Tropical Twist Alphamine!

    On top of the choline synergy research cited above,[5-9] LCLT has some strong research showing it’s effective for a more diverse population. LCLT improves endurance and blood flow while reducing damage to muscle fibers from exercise, as well as muscle soreness.[10-14]

    Lastly, LCLT increases the density of androgen receptors in muscle cells.[12,13] Basically, this means your anabolic hormones, like testosterone, work more efficiently which translates into more productive workouts.

    Ultimately, carnitine is incredible for any type of athlete, but it’s especially useful as a diet aid for those who are deficient, which is oftentimes vegans/vegetarians and vegans, as well as anyone simply not eating enough meat.

    LCLT is our preferred form of L-Carnitine for anyone building muscle, and it’s also usually dosed at 1g per day – which it appears you can get it with 2 scoops of Alphamine throughout your day.

    With leucine removed from the 2020 formula, we are extremely confident that you’re getting more carnitine and more choline. You can can always get added leucine from PEScience’s Amino IV, but truth be told, as much as we love it… leucine is an essential amino acid that you should already be getting plenty of from your diet (eat your steak!)

  • L-Ornithine

    The newest addition to Alphamine is none other than L-ornithine, a non-proteogenic amino acid that’s heavily involved in the urea cycle and is known for it’s ability to fight off fatigue! The urea cycle, also known as the ornithine cycle, is a metabolic process that helps remove toxic ammonia from the body by converting it into urea.

    PEScience Greens and Vegan Protein Powder

    PEScience launched Chocolate Peanut Butter Select Vegan Protein Powder along with Greens & Superfoods!

    Studies have shown that excessive amounts of ammonia can lead to decreased muscle functioning.[15] Fortunately, by supplementing with L-ornithine, you will be able to delay the build-up of ammonia since L-ornithine is capable of binding to ammonia, which ends up forming citrulline. Clinical trials have reported that L-ornithine can reduce feelings of fatigue.[16]

    As many of our readers already know, citrulline can help increase L-arginine levels, which gets converted into nitric oxide. As a result, your blood vessels will vasodilate, allowing more nutrient and oxygen rich blood to flow throughout the body. So not only are you decreasing ammonia levels, you’re also increasing citrulline levels, which is a win-win situation!

    Since Alphamine is mainly about giving you a nice boost of energy, L-ornithine is a great addition to the formula. A study published in Preventative Nutrition and Food Science food that the combination of caffeine and L-ornithine is capable of elevating your mood and that there was a unique synergistic effects between the two ingredients.[17] If this new version of Alphamine feels different than before, it’s probably because of this ingredient!

  • L-Theanine

    Theanine is a non-dietary amino acid predominantly found in tea leaves. However, looking around the pre workout and fat burner market, it’s found pretty frequently there as well. The reason is that theanine helps smooth out the jarring effects of stimulants, eliminating that “on edge” or jittery feeling.

    Additionally, theanine also enhances the cognitive focus effects of caffeine[18], and alleviates symptoms of stress, anxiety, and fatigue.[19,20]

    This is an ingredient the industry has been adding to supplements more and more lately, and it feels quite good to most users.

  • Caffeine Anhydrous – 125mg

    There’s not much to mention here that you probably don’t already know. Caffeine is as commonplace in energy drinks, fat burners, and pre workouts as just about anything. It’s a great energy booster, but also helps improve focus, alertness and even enhances fat burning a smidge.[21,22]

    PEScience Sour Green Apple Tropical Twist PricePlow

    New formula and new refreshing flavors!

    Caffeine expresses its effects via the inhibition adenosine and phosphodiesterase. Adenosine is a nucleoside that causes a decrease in neural activity when it binds to its receptor. Caffeine blocks this from occurring, causing a increase in energy and cognition.[21,22]

    Having more energy will definitely help you burn more calories throughout the day, but caffeine can also help increase your metabolism at rest! But how is that possible?

    Phosphodiesterase is an enzyme that breaks down a secondary messenger called cyclic adenosine monophosphate (cAMP), which is involved in lipid and carbohydrate metabolism.[22] Having sufficient levels of cAMP around is crucial for turning carbs and fats in usable forms of energy, rather than storing them for later.[22]

    Furthermore, caffeine can help suppress your appetite, which can be extremely beneficial if you suffer from intense cravings during dieting or exercise. PEScience is using the same dose here as they did in the previous version of Alphamine, which makes it easily scalable depending on how high your stim tolerance is.

Alphamine Flavors

The formula isn’t the only thing that’s changed for Alphamine, so have the flavor options! At one point in time, Alphamine was available in nearly seven flavors, however PEScience decided to dial it back and really perfect each flavor. The flavor list may be a bit smaller now, but they taste better than ever.

They recently added Tropical Twist and Sour Green Apple to the lineup and both were a homerun. We won’t be surprised if PEScience adds more flavors in the future, especially with the new formula, so check back on this post for any updates.

Alphamine Capsules

Rather take a pill than a powder? Then look at Alphamine Capsules, which bring PQQ to the fat burning party.

Here’s an updated list of all available Alphamine flavor variations:

    Also keep in mind that there’s an Alphamine Capsule based formula that harnesses the power of PQQ!

    Why a 60 serving tub?

    Alphamine used to come in a 84 serving tub, however if you took one scoop every day it would last you three months and that led to some issues with the stability of the powder. Some customers even reported clumping. Therefore, PEScience listened to the customer feedback and adjusted both the formula and serving size.

    Now Alphamine is available in a 60 serving tub, which still will last you at least two months if you take it daily — and it’ll have no clumping issues! Alphamine is still one of the most affordable “energy drinks” on the market, clocking in at just $0.66 per serving (that’s at full price, you can use code PricePlow to get save even more money).

    PEScience Keeps Getting Better

    Alphamine has undergone several formula changes since it was introduced to the supplement industry in 2012, but this new version may be the best one yet. Although Alphamine is known as “The Athlete’s Energy Drink”, it offers a lot more than just 125mg of caffeine. If you’re looking for a delicious and affordable drink to kick start the day and get your metabolism fired up, then Alphamine is the perfect choice.

    PEScience Prolific High Volume Dumbbells

    Crush your workouts with the help of PEScience!

    PEScience continues to evolve with the ever-changing supplement industry. It’s great to see that they are open to customer feedback and willing to make changes to improve their products. PEScience has always been dedicated to creating products with the highest quality ingredients backed by research. In addition to that, they have also mastered the flavoring game and now offer several unique, refreshing, and delicious product across their entire supplement lineup.

    In 2020 alone, PEScience has launched a new flavor of their fan favorite protein bar, along with an innovative greens powder, called Superfoods & Greens, and added several amazing flavors to their flavor menus, such as Chocolate Peanut Butter Select Vegan, Sour Green Apple Prolific, Amino VI, Alphamine, and High Volume, and Tropical Twist Alphamine.

    Needless to say, PEScience continues to deliver and their long-time fans are absolutely loving all the product drops. Subscribe down below for more PEScience news, deals, reviews, and interviews from PricePlow.

    PEScience Alphamine – Deals and Price Drop Alerts

    Get Price Alerts

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    Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

    Posts are sponsored in part by the retailers and/or brands listed on this page.

    PS: For a stroll down memory lane, you can see the href=”” rel=”noopener” target=”_blank”>original Alphamine label from when it included yohimbe!

    About the Author: Mike Roberto

    Mike Roberto

    Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

    Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

    4 Comments | Posted in , | Tagged , , , , , , , , , .


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    2. Poly, C, et. al; “The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort“; The American Journal of Clinical Nutrition; December 2011
    3. Diamond, I, et. al; “The relationship of choline acetyltransferase activity at the neuromuscular junction to changes in muscle mass and function“; The Journal of Physiology; January 1974
    4. Diamond, I, et. al; “The relationship of choline acetyltransferase activity at the neuromuscular junction to changes in muscle mass and function“; The Journal of Physiology; January 1974
    5. Carnitine and Choline Supplementation with Exercise Alter Carnitine Profiles, Biochemical Markers of Fat Metabolism and Serum Leptin Concentration in Healthy Women
    6. Elsawy G, Abdelrahman O, Hamza A. Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes. Journal of Human Kinetics. 2014;40:77-82. doi:10.2478/hukin-2014-0009.
    7. Dodson WL, Sachan DS. Choline supplementation reduces urinary carnitine excretion in humans. Am J Clin Nutr. 1996;63(6):904-910.
    8. Hongu N, Sachan DS. Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. J Nutr. 2003;133(1):84-89.
    9. Daily JW 3rd, Sachan DS. Choline supplementation alters carnitine homeostasis in humans and guinea pigs. J Nutr. 1995;125(7):1938-1944.
    10. Volek JS, Judelson DA, Silvestre R, Yamamoto LM, Spiering BA, Hatfield DL, Vingren JL, Quann EE, Anderson JM, Maresh CM, Kraemer WJ. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol,2008 Nov 15;102(10):1413-7
    11. Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, French DN, Silvestre R, Hatfield DL, Van Heest JL, Vingren JL, Judelson DA, Deschenes MR, Maresh CM.Androgenic responses to resistance exercise: effects of feeding and L-carnitine. Med Sci Sports Exerc, 2006 Jul;38(7):1288-96
    12. Ho JY, Kraemer WJ, Volek JS, Fragala MS, Thomas GA, Dunn-Lewis C, Coday M, Häkkinen K, Maresh CM.l-Carnitine l-tartrate supplementation favorably affects biochemical markers of recovery from physical exertion in middle-aged men and women. Metabolism, 2009 Dec 30
    13. Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, French DN, Silvestre R, Hatfield DL, Van Heest JL, Vingren JL, Judelson DA, Deschenes MR, Maresh CM. Androgenic responses to resistance exercise: effects of feeding and L-carnitine. Med Sci Sports Exerc. 2006 Jul;38(7):1288-96.
    14. Parandak K, Arazi H, Khoshkhahesh F, Nakhostin-Roohi B. The effect of two-week L-carnitine supplementation on exercise -induced oxidative stress and muscle damage. Asian J Sports Med. 2014 Jun;5(2):123-8.
    15. McDaniel, John et al; “Hyperammonemia results in reduced muscle function independent of muscle mass”; American journal of physiology: Gastrointestinal and liver physiology; vol. 310,3; 2015; G163-70;
    16. Sugino, T, et al; “L-Ornithine Supplementation Attenuates Physical Fatigue in Healthy Volunteers by Modulating Lipid and Amino Acid Metabolism.”; Current Neurology and Neuroscience Reports; U.S. National Library of Medicine; Nov. 2008;
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    19. Kimura K, et al.L-Theanine reduces psychological and physiological stress responses. Biol Psychol. (2007)
    20. Owen GN, et al.The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. (2008)
    21. Davis JK and Green JM; “Caffeine and anaerobic performance: ergogenic value and mechanisms of action;” Sports Med. 2009;39(10):813-32;
    22. Diepvens, K et al; “Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea;” American Journal of Physiology; 2007;

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