Anastasis Konnect — The Professional’s Nootropic

Anastasis Konnect

Check out the super nootropic supplement from Anastasis Nutraceuticals. Konnect will ignite your productivity and focus.

A few weeks back, we introduced Anastasis Nutraceuticals, a biohacking company founded by the owner of Inspired Nutraceuticals. Back when we first discussed Anastasis, we had a glimpse of its first two products, but didn’t know much in the way of the final profile.

Well, the company has officially launched its IndieGoGo campaign and revealed the full formulas, and all we can say is if you’re a nootropics fiend, you will want to check this out!

We’re talking about doses like 1200mg Alpha GPC here!!!

Anastasis Konnect is a focus / productivity formula designed for anyone from college students to high-level CEOs looking to increase alertness, energy, concentration, and memory while reducing mental fatigue.

We’ve got all the details ahead, but first, make sure to sign up for PricePlow alerts and check the best deal:

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Konnect Ingredients

Konnect is a mental elixir that in the words of Anastasis Nutra “aims to elevate, not over stimulate.” In line with that, you’ll see some whopping doses of some very prominent nootropics coupled with a very moderate dose of caffeine.

  • Alpha GPC (1,200mg)

    Anastasis Konnect Ingredients

    Konnect is packing a monstrous 1,200mg dose per full serving to spark acetylcholine production and focus.

    Holy freaking choline! This is as massive of a dose of Alpha GPC as we’ve ever encountered in a supplement!

    Alpha GPC is an extremely bioavailable form of choline, and one of our favorites alongside CDP-choline, that supports increased acetylcholine production in the body. Increased levels of the “learning neurotransmitter” bolster communication between cells enhancing your focus, concentration, and learning.[1,2,3]

    Moreover, choline also enhances overall health and supports optimal liver function. Deficiencies in choline can affect CNS development, cell differentiation, and muscle tissue.[4,5,6] Konnect delivers 1,200mg per 2-scoop serving supporting your cognitive function and health.

    Right off the bat, you know this one won’t be cheap, but it’s going to be damn effective.

  • KSM-66 (600mg)

    KSM-66 is one of the premier forms of Ashwagandha extract on the market. Used heavily in Ayurveda, this potent herb helps combat stress and reduce mental fatigue, which can accumulate after a rough day at work.[7,8] Improving your stress response, enhances your cognitive performance and reaction time, key features for an “on the go” business exec.[9,10]

  • TeaCrine 40% (400mg)

    Anastasis Konnect Coffee

    1 can of Konnect is equal to roughly 40 cups of coffee. The difference is you’ll get a whole lot more for your money!

    Konnect includes 400mg of tasteless teacrine, which yields a total of 160mg pure theacrine. This caffeine relative imparts long-lasting energy, without the tolerance buildup,[11,12] ensuring each dose of Konnect hits exactly the same each and every time.

    Wehn paired with caffeine, as it is here, theacrine enhances focus and concentration. You’ll also get a nice boost in mood due to the increase in dopamine that theacrine gives.[13]

  • DMAE (250mg)

    Not to be confused with DMAA, Dimethylaminoethanol (DMAE), is a precursor to choline that boosts acetylcholine production.[14] Adding it on top of the massive Alpha GPC dose listed above provides a two-pronged attack, ensuring your acetylcholine production is never lacking.

  • Natural Caffeine (175mg)

    Konnect includes 175mg natural caffeine per full 2-scoop serving. Derived from green tea, natural caffeine provides a “smooth and calm” awakening to your CNS, absent the harsh kick in the teeth reticent of caffeine anhydrous. There’s also a smoother “let down” in energy from natural caffeine as opposed to anhydrous which can oftentimes “bottom you out.”

    Caffeine does more than just supply energy though, it can also potentiate the effects of choline in the body, and inhibit acetylcholinesterase (the enzyme that degrades acetylcholine). This means more acetylcholine production that lasts longer too.[15,16] And don’t forget that caffeine increases dopamine levels, focus, and memory all while reducing mental fatigue.[17,18]

  • Eria Jarensis (150mg)

    Anastasis Konnect Features

    Better focus, concentration, alertness, memory and energy — you get it all with Konnect.

    The sole exotic stim that seems to have any chance of surviving these days is Eria Jarensis, a unique plant containing several different PEA alkaloids, most notably N-phenethyl dimethylamine.[19] Eria provides long-lasting mood enhancement, unlike regular PEA that lasts all of 15 minutes, if that.

  • Theobromine (25mg)

    Theobromine is an alkaloid structurally similar to caffeine, that’s derived from cacao. While caffeine provides a more aggressive, acute hit of energy, theobromine provides smoother, more sustained energy to the body.[20]

    As for cognitive-boosting effects, theobromine increases blood flow and oxygenation to the brain (much like Vinpocetine) and provides antioxidant protection too. Adding theobromine to Konnect offsets the potential restricted blood flow and reduced gray matter that comes as a byproduct of daily caffeine usage.[21] FYI, cerebral blood flow is an important metric for concentration, cognition, and focus.  

  • N-Methyl Tyramine (20mg)

    N-Methyl Tyramine (NMT) is a stimulant that doesn’t get used as frequently these days, but is indeed fairly potent. It increases production of several catecholamines including dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline).[23,24] This cascade of dopaminergic, adrenergic, and serotonergic neurotransmitters heightens focus, motivation and alertness, and is a nice “topper” to the rest of Konnect.

Flavors Available

Anastasis Konnect Bottle

Are you ready to Konnect?

Konnect is launching in two flavors — Strawberry Citrus and Peach Mango. Having beta-tested the samples of Konnect, we can attest the flavoring is just what you’d come to expect from Anastasis / Inspired Nutra — top notch.

Takeaway

All we can say is WOW, this sucker is definitely going to turn some heads out there. And really, we should have known something pretty epic was coming since the founder of Anastasis is the same as Inspired Nutraceuticals, creators of one of our favorite pre workouts in DVST8.

Konnect will ignite your neurons and have your brain whizzing away at warp speed. The launch is underway, and if you’re looking for a cognitive booster, you owe it to yourself to try this one.

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References

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  2. Michel V, Yuan Z, Ramsubir S, Bakovic M. Choline transport for phospholipid synthesis. Exp Biol Med (Maywood). 2006;231(5):490-504. https://www.ncbi.nlm.nih.gov/pubmed/16636297
  3. Armah CN, Sharp P, Mellon FA, et al. L-alpha-glycerophosphocholine contributes to meat’s enhancement of nonheme iron absorption. J Nutr. 2008;138(5):873-877. https://www.ncbi.nlm.nih.gov/pubmed/18424594
  4. De Jesus Moreno Moreno M. Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: A multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther. 2017;25(1):178-193. doi:10.1016/S0149-2918(03)90023-3. http://www.clinicaltherapeutics.com/article/S0149-2918(03)90023-3/abstract
  5. Canal N, Franceschi M, Alberoni M, Castiglioni C, De Moliner P, Longoni A. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol. 1991;29(3):103-107. https://www.ncbi.nlm.nih.gov/pubmed/2071257
  6. Tayebati SK, Tomassoni D, Nwankwo IE, et al. Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain. CNS Neurol Disord Drug Targets. 2013;12(1):94-103. https://www.ncbi.nlm.nih.gov/pubmed/23244432
  7. Singh, N., Nath, R., Lata, A., Singh, S., Kohli, R., & Bhargava, K. (1982). Withania Somnifera (Ashwagandha), a Rejuvenating Herbal Drug Which Enhances Survival During Stress (an Adaptogen). International Journal of Crude Drug Research, 20(1): 29-35. Retrieved from http://www.tandfonline.com/doi/abs/10.3109/13880208209083282
  8. Mishra, L., Singh, B., & Dagenais, S. (2000). Scientific basis for the therapeutic use of Withania Somnifera (AShwagandha): A review. Alternative Medicine Review, 5(4): 334 – 346. Retrieved from http://www.altmedrev.com/publications/5/4/334.pdf
  9. Pingali U, Pilli R, Fatima N. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants. Pharmacognosy Res. 2014;6(1):12-18. http://www.naturalmedicinejournal.com/journal/2014-05/effect-ashwagandha-tests-cognitive-and-psychomotor-performance
  10. Karnick CR. A double-blind, placebo-controlled clinical studies on the effects of Withania somnifera and Panax Ginseng extracts on psychomotor performance in healthy Indian volunteers. Indian Med. 1991;3:1–5
  11. Cauli, O;Subchronic caffeine exposure induces sensitization to caffeine and cross-sensitization to amphetamine ipsilateral turning behavior independent from dopamine release.; Department of Toxicology and Centre of Excellence for Neurobiology of Dependence, University of Cagliari; 2008 http://www.ncbi.nlm.nih.gov/pubmed/12865902
  12. Li WX, et al.; “Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice.“; J Agric Food Chem.; 2013. http://www.ncbi.nlm.nih.gov/pubmed/23678853
  13. Feduccia A, et al.; “Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.”; Pharmacol Biochem Behav; 2012. http://www.ncbi.nlm.nih.gov/pubmed/22579816
  14. Dubois B, Zaim M, Touchon J, et al. Effect of six months of treatment with V0191 in patients with suspected prodromal Alzheimer’s disease. J Alzheimers Dis. 2012;29(3):527-535. doi:10.3233/JAD-2012-111370. https://www.ncbi.nlm.nih.gov/pubmed/22330824
  15. Johnson DA, Ulus IH, Wurtman RJ. Caffeine potentiates the enhancement by choline of striatal acetylcholine release. Life Sci. 1992;51(20):1597-1601. https://www.ncbi.nlm.nih.gov/pubmed/1435067
  16. Pohanka M, Dobes P. Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase. International Journal of Molecular Sciences. 2013;14(5):9873-9882. doi:10.3390/ijms14059873. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676818/
  17. Loke WH. Effects of caffeine on mood and memory. Physiol Behav. 1988;44(3):367-372. https://www.ncbi.nlm.nih.gov/pubmed/3222359
  18. Sherman SM, Buckley TP, Baena E, Ryan L. Caffeine Enhances Memory Performance in Young Adults during Their Non-optimal Time of Day. Frontiers in Psychology. 2016;7:1764. doi:10.3389/fpsyg.2016.01764. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107567/
  19. Hedman, K; Phenethylamines from Eria Jarensis Ames; Acta Chemica Scandinavica, Volume 23; 1969; Retrieved from http://actachemscand.org/pdf/acta_vol_23_p3261.pdf
  20. Nehlig A. The neuroprotective effects of cocoa flavanol and its influence on cognitive performance. British Journal of Clinical Pharmacology. 2013;75(3):716-727. doi:10.1111/j.1365-2125.2012.04378.x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575938/
  21. Rusconi M, Conti A. Theobroma cacao L., the Food of the Gods: a scientific approach beyond myths and  claims. Pharmacol Res. 2010;61(1):5-13. doi:10.1016/j.phrs.2009.08.008. https://www.ncbi.nlm.nih.gov/pubmed/19735732
  22. Franco R, Oñatibia-Astibia A, Martínez-Pinilla E. Health Benefits of Methylxanthines in Cacao and Chocolate. Nutrients. 2013;5(10):4159-4173. doi:10.3390/nu5104159. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820066/
  23. Tsutsumi E, Kanai S, Ohta M, Suwa Y, Miyasaka K. Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats. Alcohol Clin Exp Res. 2010;34 Suppl 1:S14-7. doi:10.1111/j.1530-0277.2009.00893.x. https://www.ncbi.nlm.nih.gov/pubmed/19298333
  24. Stohs SJ, Hartman MJ. A review of the receptor binding and pharmacological effects of N-methyltyramine. Phytother Res. 2015;29(1):14-16. doi:10.1002/ptr.5231. https://www.ncbi.nlm.nih.gov/pubmed/25274429
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