Nutrex Research NIOX: Reformulated For Enhanced Pumps, Performance, and Gains!

Some people go to the gym to relieve stress, work up a sweat, and enhance their cardiovascular endurance. But others are on a mission to get an epic pump while lifting maximal amounts of weight and building maximal amounts of muscle!

Nutrex NIOX

NIOX is a non-stim pump enhancer that can be taken on it’s own or stacked with other pre workouts!

The “pump”, is what the bros in your gym are referring to when the muscle swells from being filled with excessive amounts of blood. This occurs because as the muscle approaches exhaustion, the body is doing everything it can to meet the demand of the physical stressor placed upon it. More blood flow will be directed towards the working muscles to deliver a greater amount of oxygen, nutrients, and help shuttle away metabolites, such as lactic acid.

The scientific term for the pump is called “hyperemia” – it’s been shown to be an important factor for maximal hypertrophy.[1] Over the years, researchers have been able to identify three primary mechanisms that cause a muscle to grow bigger and stronger – metabolic stress, mechanical tension, and muscular damage. Metabolic stress is the primary mechanism responsible for getting a pump and it’s strongly correlated with stimulating several growth factors.[1]

Now that you know the importance and science behind the pump, what’s the best way to obtain it?

There are many things you can do to increase the likelihood of getting a massive pump, such as being hydrated, consuming enough electrolytes, eating a carb-dense meal pre workout, and lifting in a higher rep range with lighter loads. There’s also various supplements that can help increase blood flow and give you a bigger pump. If you’re looking to get the best results, look no further than NIOX from Nutrex Research to deliver!

NIOX: Extreme Pumps & Vascularity

NIOX is another upgraded product from the Warrior Series – it’s one of the first capsule based pre workout supplements from Nutrex! NIOX is a non-stimulant vascularity, pump, and endurance booster that can be taken on its own or stacked with several other pre workouts that Nutrex offers. Nutrex formulated NIOX to enhance blood flow to the working muscles, resulting in more oxygen and nutrients being shuttled to the area. Not only does it give you mind-blowing pumps, it also boosts performance by increasing your work capacity.

We have everything you need to know about NIOX down below, but before we dive into the details, sign up for Nutrex news and deal alerts to make sure you never pay full price for high quality supplements!

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Nutrex’s Pre Workout Packages

Nutrex Warrior Pre Graphic

Stack NIOX with Warrior Pre Workout for intense training sessions!

Nutrex Research is known for producing some pretty stimulant heavy pre workouts, such as OutLift Amped, Warrior Pre Workout, and Lipo-6 Black Training. Although they are very well formulated, sometimes you may want to tone the stimulants down a little, therefore having a stim-free option to stack with these intense pre workouts is a brilliant idea.

Before Nutrex came out with NIOX, the only other non-stim pre workout they had was Alpha Pump, which quickly became a bestseller. However, Alpha Pump also contains nootropics, making it more difficult to stack with comprehensive pre workouts. NIOX was reformulated to increase your pump and that’s it. NIOX is a more simple product, but that makes it very effective and versatile.

NIOX Ingredient Analysis

NIOX is not a new product from Nutrex, however it did get a massive upgrade with a completely revamped formula!

The original NIOX featured a combination of L-Arginine ethyl ester, glycerine, AgmaPure Agmatine Sulfate, and CarnoSyn Beta-Alanine. Although that’s a pretty solid mix of ingredients, newer ingredients have hit the market, which fit the purpose of this product better. After looking at the upgraded formula and seeing the reviews online, we would say Nutrex crushed this product!

Nutrex recommends taking one serving (4 capsules) of NIOX two times a day and on training days, take one serving an hour prior to hitting the gym. Unlike several other pre workout products on the market, it’s best to take NIOX daily for optimal results.

Now that you know a good amount of information about NIOX, let’s see what this thing is made of! Here’s what one serving of NIOX has to offer:

  • Glycerol Monostearate – 1g

    The first ingredient included in NIOX is Glycerol Monostearate (GMS) and it’s here to make sure your muscle cells are hyperhydrated! You’ve likely seen glycerol in several pre workouts that come in powdered form, however there’s one main issue that almost always comes up – clumping.

    Nutrex NIOX Ingredients

    NIOX features a combination of three potent pump inducing ingredients along with BioPerine to increase absorption!

    If you’ve bought a pre workout that ends up clumping and turning in a hard rock, you can blame it all on glycerol. But how can you solve this issue – by putting it into a capsule instead! Beyond the dreaded clumping and grittness that comes from drinking glycerol powder, it’s a phenomenal pump and endurance booster, which is why we’re happy to see Nutrex including it in this product.

    Glycerol is classified as a naturally occuring sugar alcohol, which has a similar structure as the sugar alcohols that are added to various foods,[2] however glycerol works much differently when ingested. Glycerol is known for its ability to attract water, meaning it can accumulate fluid into the cells, resulting in a state of hyperhydration.[2-6]

    This is very advantageous for not only getting a pump, but also increasing performance. As we mentioned in the intro, being hydrated is one of the best things you can do to obtain a massive pump, thus taking glycerol along with a good amount of water can really amplify the effects. On the PricePlow blog, we like to call this the “water-based pump” since the cells are swollen with fluid!

    Studies have shown that supplementing with glycerol along with a sufficient amount of water can keep you hydrated throughout the training session, resulting in decreased risk of heat exhaustion, significantly greater endurance capacity, and aerobic power![4-6]

    Stearic acid: a saturated fat worth looking into

    Glycerol monostearate is glycerol bound to stearic acid. Few talk about it, but we’ve become fans of this saturated fatty acid, as it is found in animal fats and seems to promote fullness. If you’re not eating meat or beef tallow or butter/ghee (or cocoa butter for plant-based sources), there’s a good chance you’re not getting much of this saturated fat.

    It’s important to note that glycerol uses different mechanisms to induce a pump then any other pump ingredient, which means it will work synergistically and may result in more profound effects.

  • Green Tea Extract (leaf) (as VASO6®) – 300mg

    VASO6® comes from an industry leading ingredient developer, Compound Solutions. It features a blend of six different compounds derived from green tea leaves that work synergistically to vasodilate (expand) the blood vessels, which is what it’s named after! It’s obvious that Nutrex is a big fan of VASO6®, as you can also find it in Alpha Pump.

    Nutrex Research Swole Boys

    Want to get jacked? Then you better be getting a good pump in the gym!

    VASO6® is one of the newer ingredients in the sports supplement industry, but it caught on fast since at the end of the last decade it’s been shown to be a potent nitric oxide booster.[7-9] Nitric oxide (NO) is produced by endothelial cells within the walls of your blood vessels and it essentially tells them to expand, allowing more blood flow, nutrients, and oxygen into the area.

    Research has found that VASO6® supplementation significantly enhances blood flow, improves glucose uptake into muscle cells, and has a positive effect on muscle protein synthesis.[7,8] It carries out these effects by interacting with the enzyme that naturally produces NO, known as nitric oxide synthase.[8] VASO6® naturally increases nitric oxide levels by boosting nitric oxide synthase activity.

    Furthermore, other studies have reported that VASO6® is capable of inducing relaxation of the vasculature by up to 15%.[9] This is attributed to it’s high content of epicatechin from the green tea leaves.[9]

    300mg is a great dose for VASO6®, so expect to get some massive pumps in no time!

  • Grape Seed Extract (Vitis Vinifera) – 50mg

    Next up on our list of pump enhancing ingredients is grape seed extract (GSE), also known as vitis vinifera. GSE is produced by removing the seeds from grapes, drying, and crushing them into a powder. They are rich in antioxidants, such as flavonoids, anthocyanins, and phenolic acids that all provide various health benefits!

    Nutrex Research Alpha Pump Updated

    Alpha Pump is Nutrex’s flagship non stim pre workout!

    Studies show that GSE supplementation can improve blood flow, lower blood pressure, decrease oxidative damage, improve brain, kidney, and liver health, and may even support greater levels of bone density.[10-16]

    Beyond the incredible health benefits that GSE has to offer, it’s ability to induce vasodilation of the blood vessels increases the ability for oxygen rich blood to get delivered to the working muscles.

    We’ve already explained the importance of getting enough blood flow into the area to obtain a massive pump, but it’s also crucial for increasing the amount of reps you can do. Without oxygen, the muscles will quickly run out of gas. Overall, this should lead to more muscle growth in the long run.

    The combination of glycerol, VASO6®, and GSE is almost guaranteed to give you an insane pump and we still have one more ingredient to cover!

  • BioPerine® [Black Pepper (Piper nigrum) Extract (fruit)] – 5mg

    You could almost consider BioPerine® from Sabinsa Corp. a flagship ingredient in the Warrior Series, because every product we’ve covered thus far includes 5mg to round out the formula. BioPerine® is the trademarked name for black pepper fruit extract that’s standardized to contain 95% of the bioactive constituent, piperine.[17]

    Nutrex Male Athlete Gym

    Maximize your training sessions with NIOX from Nutrex.

    Some research has shown that BioPerine® is able to enhance thermogenesis by stimulating the release of catecholamine neurotransmitters, which is quite interesting on its own.[18] However, the main reason why BioPerine® is making an appearance on several supplements’ ingredient lists is because of its ability to boost the bioavailability and absorption of a wide variety of nutrients.[17,18]

    But what does that even mean?

    Some ingredients, especially specific minerals, have a very difficult time getting absorbed by the small intestine for one reason or another. Fortunately, ingredient developers have discovered a way to solve this problem and one of them is by adding an efficacious dosage of BioPerine® into the mixture.

    Although more research is warranted, it’s theorized that piperine is able to alter key enzymes involved in metabolism and inhibit a protein that actively transports drugs out of a cell called P-glycoprotein.[18] P-glycoprotein is known for modulating intestinal absorption, therefore if piperine is able to inhibit it, then more nutrients will be able to enter into circulation.

    Needless to say, BioPerine® is very unique – it makes your supplements work that much better by reducing the percentage of ingredients that end up being excreted rather than utilized!

Watch this video to learn more about NIOX

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Add NIOX To Your Supplement Stack For A Sick PUMP!

NIOX is a very solid stand alone pump product that can be easily added to your supplement stack. It’s affordable, simple, and downright effective, which is just what you need to get a great workout without breaking the bank. If you’re serious about making the most amount of gains possible, then taking a solid pump product can definitely give you an extra boost.

Nutrex Research The Warrior Series

Warrior Pre Workout is one of nine products in the complete Warrior Series line-up.

Besides making you feel like a professional bodybuilder inside the gym, getting a good pump can significantly enhance your mind to muscle connection, in addition to improving your endurance capacity. NIOX is all about maximizing your potential to build muscle and it’s a must-try if that’s your primary goal!

Nutrex told us that the Warrior Series was formulated for the more serious consumer and NIOX is one that really stands out. It’s great to see a legacy brand that’s been around for over 20 years, continue to adapt, grow, and innovative within the supplement industry. There are far too many companies that reach a certain level and decide to just sit back.

With how many new brands are entering the supplement scene each year, the “industry veterans” are starting to get buried and left behind. Fortunately, Nutrex isn’t ready to let anyone get in the way of their legacy, so you can count on more innovative products coming from them in the near future! If you want to follow along with their journey, make sure to subscribe down below!

Nutrex NioX - Deals and Price Drop Alerts

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Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Heather Jacques

Heather Jacques

Heather Jacques, AT, ATC, has a Bachelors of Science in Exercise Science with an emphasis in Athletic Training. She is a researcher, athletic trainer, and fitness enthusiast who is PricePlow’s Digital Content Manager. Heather constantly stays up to date with the latest scientific literature in order to provide the best information for the readers.

Heather’s goal is to educate, empower, and give people the tools to reach their fitness and health related goals. There are far too many myths out there and Heather is here to provide the truth.

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References

  1. Schoenfeld, BJ.; “The Mechanisms of Muscle Hypertrophy and Their Application to Resistance Training.”; Journal of Strength and Conditioning Research; 2010; 24(10); 2857-2872; doi: 10.1519/JSC.0b013e3181e840f3; https://journals.lww.com/nsca-jscr/fulltext/2010/10000/the_mechanisms_of_muscle_hypertrophy_and_their.40.aspx
  2. “Glycerol.”; National Center for Biotechnology Information; PubChem Compound Database; U.S. National Library of Medicine; https://pubchem.ncbi.nlm.nih.gov/compound/753
  3. Nelson, Jeff L, and Robert A Robergs; “Exploring the Potential Ergogenic Effects of Glycerol Hyperhydration.”; Sports Medicine (Auckland, N.Z.); U.S. National Library of Medicine; 2007; https://pubmed.ncbi.nlm.nih.gov/17953468
  4. An Rosendal, Simon Piet, et al; “Guidelines for Glycerol Use in Hyperhydration and Rehydration Associated with Exercise.”; Sports Medicine (Auckland, N.Z.); U.S. National Library of Medicine; 1 Feb. 2010; https://pubmed.ncbi.nlm.nih.gov/20092365
  5. Lyons, T P, et al; “Effects of Glycerol-Induced Hyperhydration Prior to Exercise in the Heat on Sweating and Core Temperature.”; Medicine and Science in Sports and Exercise; U.S. National Library of Medicine; Aug. 1990; https://pubmed.ncbi.nlm.nih.gov/2402207
  6. Patlar, Suleyman et al.;”The effect of glycerol supplements on aerobic and anaerobic performance of athletes and sedentary subjects.”; Journal of human kinetics; vol. 34; 2012; 69-79; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590833/
  7. Lorenz M, Wessler S, Follmann E, et al; “A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation”; J Biol Chem; 2004; 279(7):6190-6195; https://www.jbc.org/content/279/7/6190.full.pdf+html
  8. Kim JA, Formoso G, Li Y, et al; “Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn”; J Biol Chem; 2007; 282(18):13736-13745; https://www.jbc.org/content/282/18/13736.full.pdf+html
  9. Fitzpatrick DF, Fleming C, Bing B, Maggi DA, Malley MO; “Isolation and Characterization of Endothelium – Dependent Vaso relaxing Compounds from Grape Seeds”; J Agric Food Chem; 2000; 204:6384-6390; https://pubmed.ncbi.nlm.nih.gov/11312812
  10. Zhang, Haili et al.; “The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials.”; Medicine vol. 95,33 (2016): e4247. doi:10.1097/MD.0000000000004247; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370781/
  11. Shenoy SF et al; “Effects of grape seed extract consumption on platelet function in postmenopausal women.”; Thromb Res. 2007;121(3):431‐432. doi:10.1016/j.thromres.2007.09.004; https://pubmed.ncbi.nlm.nih.gov/17950783/
  12. Aloui F, et al; “Grape seed and skin extract reduces pancreas lipotoxicity, oxidative stress and inflammation in high fat diet fed rats”; Biomed Pharmacother. 2016;84:2020‐2028. doi:10.1016/j.biopha.2016.11.017; https://pubmed.ncbi.nlm.nih.gov/27847215/
  13. Calapai G, et al.; “A Randomized, Double-Blinded, Clinical Trial on Effects of a Vitis vinifera Extract on Cognitive Function in Healthy Older Adults.”; Front Pharmacol. 2017;8:776. Published 2017 Oct 31. doi:10.3389/fphar.2017.00776; https://pubmed.ncbi.nlm.nih.gov/29163162/
  14. Khoshbaten M, et al.; “Grape seed extract to improve liver function in patients with nonalcoholic fatty liver change.”; Saudi J Gastroenterol. 2010;16(3):194‐197. doi:10.4103/1319-3767.65197; https://pubmed.ncbi.nlm.nih.gov/20616415/
  15. Turki K, et al.; “Grape seed powder improves renal failure of chronic kidney disease patients.”; EXCLI J. 2016;15:424‐433. Published 2016 Jun 27. doi:10.17179/excli2016-363; https://pubmed.ncbi.nlm.nih.gov/27822171/
  16. Ishikawa M, et al.; “Grape seed proanthocyanidins extract promotes bone formation in rat’s mandibular condyle.”; Eur J Oral Sci. 2005;113(1):47‐52. doi:10.1111/j.1600-0722.2004.00176.x; https://pubmed.ncbi.nlm.nih.gov/15693829/
  17. Sabinsa Corp; BioPerine Research Information; 2020; https://www.bioperine.com/index.php/researchhighlight
  18. Sabinsa Corp; BioPerine Mechanisms of Action; 2020; https://www.bioperine.com/index.php/mechanismsofactions

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