Dynagenix from PLT Health Solutions brings Boswellia to beverages with water solubility, neutral taste, and clinically effective doses of just 40-60mg. New research shows joint health improvements in 5 days and faster post-workout recovery.
Boswellia serrata extracts have delivered joint health benefits for years, but they've been limited to capsules and tablets. The reason? Traditional Boswellia is completely insoluble in water, tastes bitter, and requires doses of 100-250mg or higher. For brands looking to create functional beverages, shots, gummies, or ready-to-mix powders, these characteristics have made Boswellia a non-starter.
Dynagenix: A Low-Dose Beverage-Stable Boswellia from PLT Health Solutions
PLT Health Solutions' Dynagenix Muscle+Joint Formula changes that equation. This water-soluble Boswellia extract delivers clinically validated benefits at just 40-60mg per serving, with a neutral taste profile that works in any format. This is part of the growing PLT Health Beverage-Stable Platform.
New Research Showing Significant Joint Improvements... Fast
Two clinical trials -- including a new one recently announced in 2025 -- demonstrate its efficacy across different populations: adults 40-70 with joint discomfort saw significant improvements within 5 days, while recreationally active adults 25-40 experienced faster recovery from exercise-induced muscle and joint soreness.
The formulation flexibility opens doors for brands in sports nutrition, active aging, and functional beverages to create science-backed products in consumer-preferred formats. The science is covered below, but first, sign up for PricePlow's PLT Health news so you don't miss future research coverage:
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Boswellia Basics: The Challenge of Traditional Extracts
Boswellia serrata, also known as Indian frankincense, produces a gum resin used in Ayurvedic medicine for joint and inflammatory conditions. The bioactive compounds responsible for its effects are boswellic acids, with AKBA (3-O-acetyl-11-keto-β-boswellic acid) being the most potent.[1]
Formulators face major hurdles with traditional Boswellia extracts. They're hydrophobic, making them unsuitable for aqueous systems. Making things worse, they impart bitter, resinous flavors that are difficult to mask. In addition, they typically require doses of 100-250mg or higher to show clinical benefits. These limitations have effectively confined Boswellia to capsules, restricting its potential in modern supplement formats.
What Makes Dynagenix Different
Thankfully, PLT Health Solutions has the solution:
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Water-Soluble Technology
Dynagenix uses proprietary processing to create a water-soluble Boswellia extract standardized to 78% total boswellic acids, with a minimum 30% AKBA. Technical analysis shows complete solubility across pH ranges of 4.0-8.0, making it compatible with beverages, sports drinks, functional shots, and ready-to-mix powders.
The extract remains stable under both high-temperature short-time (HTST) and low-temperature long-time (LTLT) pasteurization conditions, though some gelling may occur under more extreme sterilization temperatures above 121°C.
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Neutral Taste Profile
Unlike traditional Boswellia extracts that require heavy flavoring to mask their bitter, resinous notes, Dynagenix has a neutral taste profile. This allows brands to develop clean-tasting products without compromising on flavor or requiring excessive sweeteners and masking agents.
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Low-Dose Efficacy
Clinical validation demonstrates efficacy at 40mg for joint health and 60mg for sports recovery applications. This low dose point enables cost-effective formulations while maintaining therapeutic benefits. The improved bioavailability from the water-soluble format allows these lower doses to deliver results comparable to higher doses of standard Boswellia extracts.
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Delivery System Applications
The water-soluble, neutral-tasting nature of Dynagenix enables formulation in:
- Ready-to-mix powders
- Gummies and chews
- Functional shots
- Stick packs
- Effervescent tablets
- Sports beverages
- Soft gels and capsules
This formulation flexibility allows brands to meet consumers where they prefer to take their supplements, rather than forcing them into traditional capsule formats.
Let's take a look at the two studies. We'll first focus on the newest one just announced:
Clinical Evidence Part 1: Fast-Acting Joint Health (Upadhyay, 2025)
The combined WOMAC assessment measuring pain, stiffness, and physical function showed dramatic reductions in joint discomfort, with benefits emerging as early as 5 days into supplementation.[2]
Study Overview
A 2025 randomized, double-blind, placebo-controlled trial evaluated 72 men and women (ages 40-70, mean age 53) with Grade II osteoarthritis.[2] Subjects received either 40mg/day Dynagenix or placebo for 30 days, with assessments at baseline, 5, 15, and 30 days.
The study used validated outcome measures including the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for pain, stiffness, and physical function, Visual Analog Scale (VAS) for pain intensity, functional mobility tests (6-Minute Walk Test, 30-Second Chair Stand Test, Stair Climb Test), range of motion measurements, and inflammatory biomarkers (hs-CRP, TNF-α).
Statistically Significant Benefits at Just 5 Days
The most striking finding was the speed of onset. Subjects taking Dynagenix experienced statistically significant improvements in joint comfort, stiffness, and physical function within 5 days of starting supplementation.[2] This rapid onset differentiates Dynagenix from many joint health ingredients that require weeks to show benefits.
Subjects taking Dynagenix walked farther in the same amount of time compared to placebo, demonstrating real-world functional mobility gains that translate to easier shopping trips, errands, and daily activities.[2]
30-Day Results: Comprehensive Improvements
By day 30, the Dynagenix group showed remarkable improvements across all WOMAC parameters compared to placebo:[2]
- 47% reduction in joint pain (WOMAC Pain)
- 47% reduction in joint stiffness (WOMAC Stiffness)
- 45% improvement in physical function (WOMAC Function)
- 46% improvement in overall joint health (Total WOMAC Score)
The VAS pain assessment corroborated these findings, with a 41% reduction in pain intensity at day 30.
Functional Mobility Improvements
Beyond subjective pain and stiffness measures, Dynagenix delivered measurable improvements in real-world functional capacity:[2]
The ability to stand up from a seated position improved substantially with Dynagenix supplementation, indicating better lower-body strength for everyday movements like getting out of chairs, cars, or off the toilet.[2]
- 6-Minute Walk Test: Subjects improved their walking distance by 47 meters (15% improvement), translating to a walking speed increase of 8 meters per minute. This enhancement in walking endurance has direct implications for daily activities like shopping, running errands, or recreational walking.
- 30-Second Chair Stand Test: A 25% improvement in the number of chair stands completed. This test measures the strength and power needed for common movements like standing from a seated position, getting out of a car, or rising from a toilet. The improvement indicates easier transitions and reduced fall risk.
- Stair Climb Test: A 25% improvement in stair climbing speed and pace, with subjects completing the test an average of 4 seconds faster. Stair negotiation is a key indicator of lower body function and independence in daily living.
Flexibility and Range of Motion
Dynagenix subjects showed significant improvements in knee flexibility and range of motion, with statistically significant benefits appearing by week 2 and continuing through day 30:[2]
Negotiating stairs became easier and faster for subjects using Dynagenix, shaving off several seconds by day 30 and demonstrating enhanced lower-body function critical for maintaining independence.[2]
- 14% improvement in total knee range of motion
- 51.5% improvement in knee extension (straightening the leg)
- 3.8% improvement in knee flexion (bending the leg)
The substantial improvement in knee extension has particular relevance for walking efficiency. Normal walking requires approximately 0-10 degrees of knee extension, while climbing stairs needs 0-20 degrees. The enhanced extension capacity supports easier, more efficient movement patterns.
Biomarker Validation
Clinical improvements were accompanied by reductions in key inflammatory markers. Subjects taking Dynagenix showed statistically significant decreases in high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, and tumor necrosis factor-alpha (TNF-α), a pro-inflammatory cytokine implicated in joint degradation.[2] These biomarker changes validate the anti-inflammatory mechanisms underlying the symptomatic improvements.
Clinical Evidence Part 2: Post-Exercise Recovery
Study Overview
A 2019 clinical trial, published in 2025 in Frontiers in Sports and Active Living, evaluated Dynagenix in 50 recreationally active men (ages 25-40, mean age 28).[3]
Subjects received 60mg/day Dynagenix or placebo for 10 days. On day 7, researchers induced delayed-onset muscle soreness (DOMS) through a downhill running protocol consisting of three 15-minute episodes on a 10% declined treadmill. Recovery was assessed at 24, 48, and 72 hours post-exercise using Visual Analog Scale (VAS) scores for muscle and joint soreness, one-repetition maximum leg extension (1RM-LE) for strength recovery, rating of perceived exertion (RPE), and inflammatory biomarkers.
Reduced Muscle Soreness
Muscle discomfort following eccentric exercise was noticeably lower in the Dynagenix group at every recovery checkpoint, with the most dramatic difference appearing three days after the workout.[3]
Subjects taking Dynagenix reported significantly less muscle soreness at all recovery timepoints compared to placebo:[3]
- 13% less muscle soreness at 24 hours post-exercise
- 15% less muscle soreness at 48 hours
- 47% less muscle soreness at 72 hours (during squats)
- 47% less muscle soreness descending stairs at 72 hours
The progressive improvement through the 72-hour recovery window shows that Dynagenix doesn't just mask pain but supports the underlying recovery process.
Reduced Joint Soreness
After intense downhill running, recreationally active men taking Dynagenix experienced substantially less joint discomfort during squatting movements throughout the 72-hour recovery window.[3]
Joint soreness followed a similar pattern of progressive improvement:
- 16% less joint soreness at 24 hours
- 15% less joint soreness at 48 hours
- 31% less joint soreness at 72 hours (during squats)
- 54% less joint soreness descending stairs at 72 hours
The substantial reduction in stair-descent soreness has practical implications for athletes and active individuals who need to navigate stairs after intense training sessions.
Faster Strength Recovery
Nearly all Dynagenix subjects (24 of 25) regained their full baseline strength by day 3, while less than half the placebo group achieved complete recovery, demonstrating accelerated neuromuscular restoration.[3]
The most compelling finding was the dramatic difference in full strength recovery. By day 3 post-exercise, 96% of Dynagenix subjects (24 out of 25) had recovered full baseline strength in the leg extension test, compared to only 40% (10 out of 25) in the placebo group.[3] This represents a 2.4-fold improvement in the proportion of subjects achieving complete strength recovery.
This finding has significant implications for training frequency and progression. Athletes who recover strength faster can return to training sooner without compromising performance or increasing injury risk.
Reduced Perceived Exertion
Using the Borg RPE scale, subjects taking Dynagenix consistently reported that exercise felt easier during recovery compared to placebo, suggesting improved tissue repair and reduced systemic stress.[3]
Dynagenix subjects found exercise significantly easier at all recovery timepoints based on the Borg Rating of Perceived Exertion (RPE) scale:[3]
- 22% easier at 24 hours post-workout
- 16% easier at 48 hours
- 27% easier at 72 hours
Notably, 64% of Dynagenix subjects found exercise at 72 hours to be as easy as baseline, compared to a much smaller proportion in the placebo group.
Reduced Overall Stiffness
Three days after intense eccentric exercise, subjects using Dynagenix reported markedly lower overall stiffness compared to placebo, indicating better tissue recovery and reduced residual inflammation.
At 72 hours post-exercise, Dynagenix subjects reported 37% less overall stiffness compared to placebo, indicating improved tissue recovery and reduced residual inflammation.
Inflammation Biomarker Reductions
Blood analysis revealed significant reductions in exercise-induced inflammatory markers:[3]
- Significantly reduced C-reactive protein (CRP) at 48 and 72 hours
- Significantly reduced interleukin-6 (IL-6) at 72 hours
These biomarker changes demonstrate that Dynagenix modulates the inflammatory response to eccentric exercise, creating a more favorable environment for tissue repair and recovery.
Mechanisms of Action
So how does it work? In the same fashion as AprèsFlex, PLT Health's other Boswellia ingredient that works best in capsule applications, thanks to both having AKBA inside:
Close-up view of Boswellia serrata bark showing resin collection area.
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5-Lipoxygenase Inhibition
AKBA, the primary bioactive compound in Dynagenix, is a potent inhibitor of 5-lipoxygenase (5-LOX), the enzyme responsible for synthesizing pro-inflammatory leukotrienes.[1] Unlike NSAIDs that inhibit cyclooxygenase (COX) enzymes, AKBA targets the leukotriene pathway, offering a complementary mechanism for managing inflammation without the gastric side effects associated with COX inhibition.
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Matrix Metalloproteinase Reduction
Boswellic acids reduce the activity of matrix metalloproteinases (MMPs), enzymes that degrade cartilage matrix components.[1] By inhibiting MMPs, Dynagenix helps protect the structural integrity of joint cartilage.
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Multi-Target Anti-Inflammatory Effects
Clinical biomarker data from both studies demonstrate Dynagenix's ability to reduce multiple inflammatory mediators including CRP, TNF-α, and IL-6. This multi-target approach addresses inflammation through several pathways simultaneously, potentially explaining the rapid onset and comprehensive benefits observed in both joint health and recovery applications.
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Enhanced Bioavailability
The water-soluble formulation of Dynagenix improves absorption compared to standard Boswellia extracts. This enhanced bioavailability allows lower doses to achieve therapeutic concentrations, explaining the efficacy at 40-60mg compared to the 100-250mg typically required for traditional Boswellia products.
Versatility: One Ingredient, Multiple Applications
Dynagenix's dual clinical validation positions it uniquely in the musculoskeletal health category. Few ingredients can credibly claim benefits for both aging populations managing joint discomfort and active populations seeking recovery support.
Active Aging Products
For adults 40 and older dealing with joint discomfort, Dynagenix offers:
- Rapid onset of benefits (statistically significant improvements at 5 days)
- Sustained improvements in comfort, stiffness, and function
- Enhanced mobility and walking performance
- Improved range of motion and flexibility
- Reduced inflammatory biomarkers
The low-dose, water-soluble format enables delivery in convenient, palatable formats like functional beverages, shots, and gummies that may be easier for older adults to consume than large capsules.
Sports Nutrition & Recovery
Boswellia serrata: The Indian Frankincense Tree
For active adults and athletes, Dynagenix provides:
- Reduced post-workout muscle and joint soreness
- Faster return to full strength (2.4x more subjects at baseline by day 3)
- Lower perceived exertion during recovery
- Reduced exercise-induced inflammation
- Support for more frequent training
The 60mg effective dose fits easily into ready-to-mix recovery formulas, intra-workout beverages, and post-exercise shots without adding significant bulk or affecting taste.
Daily Wellness & Functional Beverages
For proactive consumers looking to support musculoskeletal health before problems arise, Dynagenix offers an ideal ingredient for daily-use functional beverages and supplements. The water-soluble, neutral-tasting profile makes it suitable for:
- Daily wellness shots
- Functional waters and sports drinks
- Morning or evening routine gummies
- Convenience formats like stick packs
This positions Dynagenix alongside AprèsFlex, another PLT Health Boswellia ingredient designed for capsule applications. While AprèsFlex targets the traditional capsule market, Dynagenix opens entirely new product categories through its water solubility and lower dose requirements. Together, these ingredients give brands comprehensive options across the PLT Health beverage-stable ingredient platform.
Safety Profile
Clinical Safety Data
The 30-day joint health study reported zero product-related adverse events, with blood work remaining within normal ranges throughout the study period. The 10-day sports recovery study similarly showed no safety concerns, with Dynagenix demonstrating good tolerability in active populations undergoing intense exercise protocols.
Category Safety Profile
Boswellia serrata has an extensive history of safe use. A comprehensive toxicology evaluation of a related Boswellia extract demonstrated a No Observed Adverse Effect Level (NOAEL) in animal studies far exceeding human equivalent doses.[4] The water-soluble processing used to create Dynagenix does not alter the fundamental safety profile of the source material.
These factors make Dynagenix suitable for long-term daily use in both general wellness and targeted musculoskeletal support applications.
Sourcing & Sustainability
Sustainable Sourcing Practices
PLT Health Solutions sources Dynagenix's Boswellia serrata resin from Andhra Pradesh and Madhya Pradesh in India through a long-standing partnership with Laila Nutraceuticals spanning over 25 years. This relationship ensures consistent quality and supply while supporting local communities.
A third-party sustainability audit by Botanical Liaisons verified fair treatment of tribal communities involved in resin collection, appropriate compensation practices, and responsible harvesting methods that don't damage source trees. Every batch of Dynagenix includes traceability documentation connecting it to specific geographic regions and collection sites.
Quality Control
Each batch of Dynagenix undergoes comprehensive testing by multi-disciplinary teams covering:
- Botanical identification
- Chemical analysis and standardization
- Microbiology testing
- Heavy metals and contaminants screening
This rigorous quality control ensures consistency across production batches and verifies the absence of adulterants or contaminants.
Formulation Considerations
Dosing Recommendations
Clinical validation supports two distinct dose levels:
6-month study shows AprèsFlex delivers MRI-verified cartilage regeneration at just 100mg daily. Not just pain relief -- actual structural improvement. STROM UK's Rick Foster explains why this sets it apart from typical joint supplements.
- 40mg/day for joint health applications (validated in adults 40-70 with Grade II OA)
- 60mg/day for sports recovery applications (validated in recreationally active adults 25-40)
Formulators can select the appropriate dose based on their target application and audience. Both doses fit comfortably within single-serving formats across multiple delivery systems.
Compatibility and Stability
Dynagenix demonstrates excellent stability across a wide range of formulation conditions:
- pH stability: 4.0-8.0 (covers most beverage and supplement applications)
- Thermal stability: Stable under HTST and LTLT pasteurization
- Solubility: Complete dissolution in aqueous systems
- Taste: Neutral profile requiring minimal flavoring
Formulators should note that some gelling may occur under extreme sterilization temperatures above 121°C, though this is not an issue for most commercial beverage and supplement processing conditions.
Synergistic Combinations
Dynagenix pairs well with complementary musculoskeletal support ingredients:
PLT Health Solutions: Growth Through Innovation
- Curcumin extracts (such as HydroCurc) for enhanced anti-inflammatory effects through complementary mechanisms
- Collagen peptides for structural support of joints, tendons, and connective tissue
- Magnesium for muscle function, relaxation, and recovery
- Glucosamine / Chondroitin / MSM for additional joint comfort support
These combinations allow brands to create comprehensive formulas addressing multiple aspects of musculoskeletal health.
The Bottom Line: Beverage-Stable Boswellia
Dynagenix solves a fundamental formulation problem that has limited Boswellia's potential for years. By creating a water-soluble, neutral-tasting extract effective at low doses, PLT Health Solutions has opened Boswellia supplementation to modern delivery formats that consumers prefer.
Are you ready for a shake-up in the beverage space? PLT Health Solutions has worked hard to create several beverage-stable ingredients, so that we can avoid all of the me-too RTD formulas.
The clinical validation is robust: two well-designed human studies demonstrate statistically significant benefits for both joint health in older adults and post-exercise recovery in active populations. The speed of onset (5 days for joint benefits), magnitude of effects (up to 47% improvements), and functional relevance (walking performance, strength recovery) give brands compelling claims backed by solid science.
For formulators, Dynagenix offers flexibility previously unavailable in the Boswellia category. The 40-60mg effective dose, neutral taste, and water solubility enable product development across shots, gummies, ready-to-mix powders, beverages, and stick packs. The sustainable sourcing, comprehensive quality control, and established safety profile provide additional confidence for brands building long-term product lines.
Whether targeting active aging, sports nutrition, or daily wellness categories, Dynagenix delivers clinically validated musculoskeletal support in formats that fit modern consumer preferences. For brands seeking to differentiate in competitive categories with science-backed innovation, Dynagenix warrants serious consideration.
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