EndoFlo XT: SNS Optimizes Aura Scientific’s Blood Flow Complex

SNS (Serious Nutrition Solutions) has partnered with Aura Scientific to launch EndoFlo XT, an enhanced version of the clinically-studied EndoFlo formula that’s engineered for superior absorption and effectiveness. By combining EndoFlo with Bioperine black pepper extract, SNS has created a formula that may provide improved bioavailability of the four key botanical ingredients within.

The Best Way to Try Aura Scientific’s 4-Part EndoFlo Ingredient

SNS launches EndoFlo XT, featuring 300mg EndoFlo plus Bioperine for enhanced absorption. Perfect for trying Aura Scientific’s 4-part EndoFlo vascular health formula on its own.

EndoFlo has already made waves in the sports nutrition industry due to its innovative combination of mango fruit extract, black ginger, ginkgo biloba, and pine bark extract – each selected for their specific vascular health benefits. SNS has taken this formula to another level by adding the absorption enhancer, Bioperine. If you’ve been wanting to try the new ingredient on its own or with your energy drink or pre-workout, this is your chance.

For those familiar with SNS’s history of innovation, this product comes as no surprise. The brand has consistently stayed ahead of market trends, developing science-backed formulas that prioritize effectiveness over marketing hype. EndoFlo XT continues this tradition, offering the full clinical 300 milligram dose of EndoFlo paired with the research-backed 5 milligram dose of Bioperine.

SNS: The Scientific Brand That Sees The Future

Remember, SNS launched Focus XT in the 2000s — before nootropics were a known thing. When they see something big, they jump on it fast.

This launch is part of SNS’s ambitious rollout of twelve new products in early 2025, many of which feature novel ingredients from Aura Scientific. EndoFlo XT stands out among them as a straightforward yet sophisticated formula that focuses on maximizing the benefits of a single, brilliantly-created ingredient complex through enhanced delivery.

In this article, we’ll explore how EndoFlo XT works, analyzing each of its constituents and explaining how Bioperine may amplify their effects. We’ll also discuss proper dosing strategies for both pre-workout and daily health supplementation purposes.

EndoFlo XT Ingredients

Let’s look at what makes this formula work:

• EndoFlo™ (Mango [Magnifera indica] Fruit Extract, Black Ginger [Kaempferia parviflora] Root Extract, Ginkgo [Ginkgo biloba] Leaf Extract, Pine [Pinus massoniana] Bark Extract) – 300mg

  Aura Scientific’s EndoFlo is a blend of four ingredients:

  

  • Mango Fruit Extract
  • Black Ginger Root Extract
  • Ginkgo Biloba Leaf Extract
  • Pine Bark Extract

  Let’s dig into each one separately:

  • Mango [Magnifera indica] Fruit Extract

    The first constituent of EndoFlo is an extract from Mangifera indica, better known as mango fruit extract. While many know mango for its delicious tropical flavor, its extract – especially mangiferin – has emerged as one of the most promising natural compounds for supporting cardiovascular health and blood flow.

    Mangiferin, the primary bioactive compound in mango extract, is a unique polyphenol known as a “xanthone” that’s found in both the fruit and leaves of the mango tree. What makes this compound interesting is its specialized catechol structure, which provides it with powerful antioxidant properties.^[1]

    Research has shown that mangiferin works through multiple complementary mechanisms. At a cellular level, it helps protect mitochondrial function and supports healthy cellular energy production.^[2] This is important for blood vessel health, as the endothelial cells lining our blood vessels require significant energy to function optimally.

    

    This blood flow-boosting ingredient, EndoFlo, consists of four key constituents: Mangifera indica (mango fruit extract), Kaempferia parviflora (black ginger), Ginkgo biloba, and Pinus massoniana (pine bark extract).

    One of mangiferin’s most impressive attributes is its ability to support healthy inflammatory response through activation of an important cellular pathway called heme oxygenase-1 (HO-1).^[3] This pathway plays a crucial role in maintaining healthy blood vessel function and protecting against oxidative stress.

    Beyond its vascular benefits, mango extract has demonstrated impressive effects on cognitive function. Clinical research has shown that mangiferin can cross the blood-brain barrier and support healthy brain function, suggesting it may provide both immediate and long-term cognitive benefits.^[4]

    The inclusion of Mangifera indica extract in EndoFlo is clever because it works synergistically with the formula’s other ingredients. While many ingredients in the supplement industry work in isolation, mangiferin appears to enhance the effectiveness of other compounds while providing its own unique benefits.

    This powerful extract stands as a testament to the incredible potential of natural compounds – transforming a fruit we typically think of as just a healthy snack into a sophisticated tool for supporting cardiovascular health and performance.

  • Black Ginger [Kaempferia parviflora] Root Extract

    Among EndoFlo’s four powerful ingredients, Kaempferia parviflora — more commonly known as black ginger — stands out for its remarkable effects on blood flow and athletic performance. Traditional Thai medicine has long valued this dark rhizome for promoting vitality and physical performance.^[5]

    

    For now, let’s file this Kaempferia Parviflora Extract (KPE) rodent study under the “interesting” category, where it “markedly increased the muscle fiber size, muscle volume, and muscle mass, resulting in the enhancement of muscle function, such as exercise endurance and grip strength”.^[6]

    While modern science continues validating these traditional uses, recent research shows that black ginger’s benefits extend far beyond what ancient healers understood. A groundbreaking clinical study demonstrated that athletes supplementing with black ginger experienced significant improvements in grip strength and physical performance measures.^[7]

    The key to Black Ginger’s effectiveness lies in its unique profile of methoxyflavones, especially 5,7-dimethoxyflavone (DMF). These specialized compounds work through multiple pathways to enhance blood flow and support muscle function.^[8]

    Research shows that Black Ginger’s methoxyflavones can help:

    • Support healthy blood flow to working muscles^[9]
    • Enhance muscle strength and performance^[7]
    • Increase energy expenditure through improved cellular metabolism^[10]
    • Support healthy inflammatory response in muscle tissue^[8]

    Black ginger is interesting because of its ability to work synergistically with EndoFlo’s other ingredients. When combined with mango fruit extract, ginkgo, and pine bark extract, black ginger’s blood flow-enhancing properties are complemented and amplified, creating a comprehensive approach to supporting optimal circulation and performance.

    This is why we’re excited about the inclusion of black ginger in EndoFlo, and consider it an unsung hero in all of dietary supplements. Its clinically-validated benefits, combined with its long history of safe use in traditional medicine, make it an ideal component for athletes and fitness enthusiasts looking to optimize their performance naturally.

  • Ginkgo [Ginkgo biloba] Leaf Extract

    When it comes to enhancing blood flow, few botanical ingredients have as much clinical research behind them as Ginkgo biloba. While most consumers know ginkgo for its cognitive benefits, its cardiovascular effects are equally impressive and well-documented. This unique ingredient has been shown to significantly improve blood flow in both young and elderly populations.^[11]

    

    Animal models show that ginkgo biloba increases dopamine and noradrenaline levels over time,^[12] an interesting effect not commonly discussed.

    Research has demonstrated that standardized ginkgo extract can increase forearm blood flow by over 50% in healthy subjects within just a few weeks of supplementation.^[13] This remarkable improvement in circulation comes from ginkgo’s ability to promote healthy vascular function through multiple complementary mechanisms.^[14]

    The vasodilating effects of ginkgo come primarily from two classes of compounds: terpenoids (including ginkgolides A, B, C and bilobalide) and flavonoids (such as quercetin glycosides). These compounds work together synergistically – while each component shows some ability to promote blood flow individually, the combined effect is greater than the sum of its parts.^[15]

    What makes ginkgo so valuable in EndoFlo’s formula is its ability to enhance blood flow throughout the entire body. Studies have shown improved circulation not just in major arteries, but also in smaller vessels and capillaries.^[11] This systemic effect on circulation makes it an ideal complement to EndoFlo’s other blood flow enhancers.

    While many ingredients can theoretically improve blood flow in laboratory settings, ginkgo has repeatedly proven its effectiveness in real-world human studies. In clinical research, supplementation with standardized ginkgo extract has been shown to improve blood flow metrics within 3-6 weeks of consistent use.^[13]

    

    The ginkgo extract in EndoFlo is standardized to contain the research-backed levels of both terpenoids and flavonoids needed to achieve these impressive circulatory benefits. By including this time-tested botanical alongside newer innovative ingredients, EndoFlo delivers comprehensive support for healthy blood flow through multiple complementary pathways.

    And EndoFlo’s not done yet…

  • Pine [Pinus massoniana] Bark Extract

    The fourth and final constituent of EndoFlo is an extract from Pinus massoniana bark, also known as Masson’s pine — pine bark extract. This species of pine bark is rich in proanthocyanidins (PACs), which are condensed tannins with potent antioxidant properties.^[16]

    Pine bark extracts have a fascinating history in traditional medicine, where they’ve been used for centuries to treat various conditions related to cardiovascular health.^[17] Modern research has validated many of these traditional uses, especially in the realm of vascular health support.

    The oligomeric proanthocyanidins (OPCs) found in pine bark extract have demonstrated powerful effects on blood vessel function. These compounds help promote relaxation of blood vessels by supporting healthy endothelial function.^[18] Pine bark’s OPCs are great thanks to their ability to work through multiple complementary pathways to support vascular health.

    Clinical research has shown that pine bark extract can help maintain healthy blood pressure levels when they’re already in the normal range.^[19] This effect appears to be related to the extract’s ability to support proper endothelial function.^[20]

    The OPCs from pine bark have also demonstrated significant benefits for vascular health through their ability to promote healthy blood vessel function.^[16] Research has shown that these compounds can help protect against oxidative damage to blood vessel walls while supporting normal endothelial function.^[17]

    

    When combined with the other three ingredients in EndoFlo (mango fruit extract, black ginger, and ginkgo biloba), pine bark extract appears to work synergistically to support optimal vascular function. Each ingredient brings its own unique mechanisms of action, with pine bark extract contributing primarily through its rich OPC content and powerful antioxidant properties.

    In EndoFlo XT, the pine bark extract component helps round out the formula by providing complementary support to the other ingredients’ vascular-enhancing effects. The combined action of all four botanicals creates a comprehensive approach to supporting healthy blood flow and vascular function.

  You can read more details about this phenomenal ingredient in our article, “EndoFlo: Enhancing Vascular Health, Pumps, and Workout Performance“.

• Bioperine® (Black Pepper Fruit Extract [Piper nigrum]) – 5mg

  EndoFlo XT includes Bioperine, a patented black pepper extract standardized to 95% piperine.^[21-24] It’s not just for its direct metabolic effects – it’s actually included as a potent bioavailability enhancer for the formula’s other ingredients.

  Research shows that piperine can dramatically improve the absorption of various nutrients by inhibiting drug metabolizing enzymes and increasing gastrointestinal absorption. In a landmark human study, just 20mg of piperine increased the bioavailability of curcumin by an astounding 2000% compared to curcumin alone.^[25] While we don’t have curcumin here, we can learn how it worked and hypothesize how it can work with EndoFlo.

  

  Just one capsule brings some solid stimulant-free bolt-on pump effects

  The enhancement occurs through multiple mechanisms: piperine inhibits both the liver’s and intestinal wall’s glucuronidation processes, while also potentially enhancing absorption through increased blood supply to the digestive tract.^[25,26]

  By including Bioperine, EndoFlo XT aims to maximize the absorption and effectiveness of its premium ingredient blend. This strategic addition helps ensure you get the most out of every serving.

Dosage and Instructions

Take 1-2 capsules of EndoFlo XT daily. For best results, take it 30-45 minutes before exercise or physical activity. Due to its blood flow enhancement properties, this can also be used as a daily health supplement.

Conclusion: SNS Stays Ahead of the Curve

EndoFlo XT represents a forward-thinking approach to ingredient optimization, demonstrating SNS’s continued commitment to science-based supplement innovation. By combining the clinically-validated EndoFlo complex with Bioperine’s absorption-enhancing properties, SNS has created a straightforward yet sophisticated formula that may help users get more out of each dose.

What makes EndoFlo XT awesome is its versatility. Whether used as a pre-workout supplement to enhance training performance or as a daily health supplement, the formula delivers the full 300 milligram dose of EndoFlo alongside Bioperine for optimal absorption. This dual-purpose functionality, combined with SNS’s reputation for quality and value, makes EndoFlo XT an attractive option for those seeking to support their vascular health goals.

As part of SNS’s ambitious 2025 product launches featuring Aura Scientific ingredients, EndoFlo XT stands out for its focused approach. Rather than creating a complex formula with multiple ingredients, SNS chose to perfect the delivery of a single, well-researched ingredient complex. This strategic decision aligns with their long-standing philosophy of developing effective, science-based supplements that deliver real results without unnecessary additions.

For those interested in trying EndoFlo, this enhanced version from SNS offers an efficient way to experience its benefits. With twice the typical pre-workout dose and improved absorption potential, EndoFlo XT continues SNS’s tradition of staying ahead of the curve while maintaining their commitment to quality and value.