Antaeus Labs TITAN: Meet the Newest Anabolic Ingredient

Antaeus Labs Titan

Titan is an all new natural muscle builder from Antaeus Labs, creators of BAIBA and the mental productivity supp PSyche.

Big news, folks! Antaeus Labs, creator of unique supplements like BAIBA and PSyche has come up with a brand new natural anabolic ingredient that’s never before been used – and is actually healthy to boot!

Ready to become a TITAN?

We all want to be bigger, stronger, and faster, but at what price? Some people are perfectly comfortable employing the edgier side of anabolics whether it be pro hormones or outright steroid use; others though prefer to keep it as natural as possible and steer away from products acting via hormonal pathways.

Here’s where the natties run into a problem, outside of creatine, phosphatidic acid, and betaine, there really aren’t a ton of proven all-natural products that bring about serious gains in strength and size.

However, Antaeus Labs has stumbled on a brand new ingredient that’s set to turn the world of natty muscle-builders on end. Titan is a cutting edge all natural anabolic ingredient that’s got the studies to back it up.

We’ve got all the info down below, but first, take a second to check the best deal and sign up for alerts from PricePlow:

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Titan Ingredients

Titan is loaded with a very new all-natural anabolic compound named Tomatidine. It’s a complex of two ingredients rarely encountered in any type of sports supplement. The best part of this new anabolic is that it’s NON-HORMONAL! That means there’s not need to cycle it, run PCT, or employ a liver support supplement. As a matter of fact, it’s actually healthy for you!

Hold on, and feast your eyes on the next revolutionary muscle builder!

  • Ultra-Tomatidine (250mg)

    Antaeus Labs Titan Ingredients

    Titan’s new natural anabolic is Tomatidine, a steroidal alkaloid derived from the green tomato plant.

    Ultra-Tomatidine is a brand new ingredient that you’ve never encountered previously in a supplement. It’s a complex consisting of tomatidine and shilajit that provides 50mg tomatidine and 200mg shilajit per capsule.

    What the heck is tomatidine?!

    This one’s so interesting that we’ve got a full-length blog post coming on Tomatidine real soon, but in the meantime, here are the basics on this novel ingredient:

    As you may have guessed, Tomatidine comes from the humble tomato plant which is also plentiful in the powerful antioxidant lycopene, which is already well-known to the science community as a strong combatant against oxidative stress and certain forms of cancer.[1,2]

    Tomatidine, on the other hand, is much newer on the scene, and science is just beginning to emerge on what this alkaloid can do.

    A steroidal alkaloid

    Tomatidine Study Figure 3

    Tomatidine stimulates anabolism in cultured skeletal myotubes from humans and mice..[3]

    First and foremost, tomatidine is classified as a steroidal alkaloid that’s derived from green tomatoes.[4] Although tomatidine has been identified as having similar cancer-fighting properties as lycopene[5], that’s not why we’re highlighting it here. In addition to warding off the spread of disease, tomatidine has been found to be a potent natural anabolic!

    Several research trials have demonstrated that not only is the naturally occurring alkaloid healthy for you, but it’s also amazingly effective at warding off muscular atrophy and weakness.[3,4] To further expound on the benefits of this newfound muscle builder, tomatidine has been shown to:

    • increase skeletal muscle mTORC1 signaling,
    • reduce skeletal muscle atrophy,
    • enhanced recovery,
    • stimulate skeletal muscle hypertrophy, and
    • increase strength and exercise capacity[3]

    On mTORC1 Signaling

    Tomatidine Study Figure 4

    Tomatidine stimulates mTORC1 activity in mouse skeletal muscle.[3]

    The reason mTORC1 signaling is so important is because mTORC1 signaling stimulates muscle growth (a.k.a. hypertrophy) and reduces muscle atrophy (a.k.a muscle wasting) via several different means including elevated protein synthesis, increased mitochondrial biogenesis, and greater expression of anabolic genes encoding insulin-like growth factor.[3]

    This is a huge home run for both natty and non-natty athletes. Increasing mTOR pathway signaling is one of the best ways to boost muscle-building when you are well-fed. Suffice it to say this stuff is very intriguing, and warrant much, MUCH more attention from us and other supplement manufacturers.

    It’s actually healthy!

    To put the proverbial “icing on the cake,” tomatidine is actually good for you, unlike some many other questionable “anabolics” on the market. A comprehensive review of the alkaloid found that it reduces both serum and LDL (bad) cholesterol, as well as a significant reduction in atherogenesis (formation of plaque on the interior lining of arteries).[6]

    We always knew that tomatoes were healthy – but now we’re seeing that when extracted properly, they can be anabolic as well!

    Why package with shilajit?

    Tomatidine Study Figure 7

    Tomatidine-induced muscle hypertrophy is accompanied by reduced adiposity.[3]

    Now that you’ve gotten somewhat of a grasp on what in the world tomatidine is, the next question you’re probably pondering is why in the world is it packaged alongside shilajit instead of being wrapped in a liposome, which have been shown to be amazing for improving the bioavailability of certain compounds.

    The main reason it’s here is that shilajit enhances the bioavailability of compounds its packaged with. The main bioactive of shilajit is Fulvic Acid which has been shown in a few trials to enhance the bioavailability of other poorly absorbed ingredients, namely furosemide.[9,10] No trials have yet been run with tomatidine, but we have a sneaking suspicion it’s just as effective at increasing absorption.

    But it also may increase testosterone!

    However, Shilajit may also have its own anabolic and pro-testosterone properties, in addition to its historical role in Ayurveda as a natural remedy for a number of maladies. Recent studies on the compound have shown that it increased both testosterone secretion and stimulation.[7] Furthermore, another clinical trial on shilajit showed that it “resulted in skeletal muscle adaptation through upregulation of ECM-related genes that control muscle mechanotransduction properties, elasticity, repair, and regeneration.”[8]

    In other words, shilajit positively affected the muscle’s pliability, and its ability to repair itself when subject to stress or damage. This is yet another pro-anabolic benefit to Titan!

Shilajit Study Table 2

Effect of PS (purified shilajit) on testosterone and its mediators with respect to placebo control.[8]

If you need more information, you can now read even more in-depth details on our main tomatidine article.

Dosing

For maximum benefit, take one capsule twice daily. For optimal absorption, Antaeus Labs recommends that you consume your servings of Titan with a meal.

Under no circumstances should you consume more than six capsules per day.

Takeaway

Antaeus Labs is once again rocking the boat of the natural supplement industry. You might not know this, but they were behind the release of the original epicatechin supplements, and still nobody else has BAIBA figured out.

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So uncovering novel natural ingredients isn’t anything new for Antaeus Labs, who often operate as a raw material supplier for some of these ingredients. But this time, they’ve got a product with it on their own, and Titan looks like it’s possibly the next big landmark in Antaeus’ quest to provide top quality supplements for the best natural gains possible.

If you’ve tried just about all the other natty products out there with no success, and don’t want to venture into the land of anabolics, take Titan for a ride and let the gains come a trucking!

We’re going to be testing this one out in January 2017, and if the reviews match the theory, then it just might be time to update our next-generation muscle building supplements guide!

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References

  1. Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. CMAJ: Canadian Medical Association Journal. 2000;163(6):739-744.
  2. Chen P, Zhang W, Wang X, et al. Lycopene and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Scott L, ed. Medicine. 2015;94(33):e1260. doi:10.1097/MD.0000000000001260.
  3. Dyle MC, Ebert SM, Cook DP, et al. Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy. The Journal of Biological Chemistry. 2014;289(21):14913-14924. doi:10.1074/jbc.M114.556241.
  4. Ebert SM, Dyle MC, Bullard SA, et al. Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. The Journal of Biological Chemistry. 2015;290(42):25497-25511. doi:10.1074/jbc.M115.681445.
  5. Friedman M. Anticarcinogenic, Cardioprotective, and Other Health Benefits of Tomato Compounds Lycopene, α-Tomatine, and Tomatidine in Pure Form and in Fresh and Processed Tomatoes. Journal of Agricultural and Food Chemistry 2013 61 (40), 9534-9550. DOI: 10.1021/jf402654e
  6. Fujuwara Y, Kiyota N, Tsurushima K, et al. Tomatidine, a Tomato Sapogenol, Ameliorates Hyperlipidemia and Atherosclerosis in ApoE-Deficient Mice by Inhibiting Acyl-CoA:cholesterol Acyl-transferase (ACAT). Journal of Agricultural and Food Chemistry 2012 60 (10), 2472-2479. DOI: 10.1021/jf204197r
  7. Pandit, S., Biswas, S., Jana, U., De, R. K., Mukhopadhyay, S. C. and Biswas, T. K. (2016), Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers. Andrologia, 48: 570–575. doi:10.1111/and.12482
  8. Das Amitava, Datta Soma, Rhea Brian, Sinha Mithun, Veeraragavan Muruganandam, Gordillo Gayle, and Roy Sashwati. The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation. Journal of Medicinal Food. July 2016, 19(7): 701-709. doi:10.1089/jmf.2016.0010.
  9. Mirza MA, Ahmad N, Agarwal SP, Mahmood D, Khalid Anwer M, Iqbal Z. Comparative evaluation of humic substances in oral drug delivery. Results in Pharma Sciences. 2011;1(1):16-26. doi:10.1016/j.rinphs.2011.06.001.
  10. Suraj Prakash Agarwal, Mohammad Khalid Anwer, and Mohammad Aqil. Complexation of Furosemide with Fulvic Acid Extracted from Shilajit: A Novel Approach. Drug Development And Industrial Pharmacy Vol. 34 , Iss. 5,2008
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