As wildfire season approaches, respiratory health becomes crucial. Life Extension Healthy Lungs with AlvioLife delivers clinically-proven support with 16% improvement in lung function and 30% increase in capacity in just 6 weeks.
As wildfire season approaches and environmental air quality concerns continue to rise, the importance of respiratory health has never been more apparent. We often take breathing for granted… until it becomes difficult. Maintaining lung function becomes increasingly vital as we age, especially in today’s world of urban pollution, seasonal allergens, pets, and indoor air contaminants.
Healthy Lungs, with PLT Health’s AlvioLife
Anchored by PLT Health’s AlvioLife lung health ingredient, Life Extension Healthy Lungs delivers a science-backed approach to respiratory wellness, combining four clinically-studied ingredients that work synergistically to support lung function, promote healthy airways, and protect against environmental stressors. Life Extension has built their reputation on creating comprehensive, research-driven formulas, and this lung support supplement continues that tradition with a focused approach to breathing easier.
Respiratory health declines naturally with age, but this process can be accelerated by poor air quality, whether from urban environments, wildfire smoke, or indoor pollutants. The compounds in Life Extension Healthy Lungs target multiple aspects of respiratory wellness, from supporting healthy inflammation responses in lung tissue to promoting bronchial relaxation and protecting against oxidative stress.
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Life Extension Healthy Lungs Ingredients
Each vegetarian capsule of Life Extension Healthy Lungs provides the following:
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AlvioLife – 200mg
AlvioLife is a patented composition combining two powerful botanical extracts: Boswellia serrata gum resin standardized to 15% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) and Aegle marmelos (bael) fruit extract standardized to 0.3% imperatorin. This synergistic 1:1 ratio creates a unique respiratory support ingredient that’s backed by compelling clinical research.
Boswellia serrata has been used for thousands of years in Ayurvedic medicine for its powerful anti-inflammatory properties. Modern research has identified AKBA as the most potent active compound, with a unique ability to inhibit 5-lipoxygenase (5-LOX), a key enzyme in the inflammatory process.[1] Unlike common antioxidants that work through general redox mechanisms, AKBA specifically targets and blocks 5-LOX activity, preventing the production of inflammatory leukotrienes that can trigger bronchoconstriction and airway inflammation.
Aegle marmelos, commonly known as bael fruit, has been revered in Indian traditional medicine for over 5000 years and provides the perfect complement to Boswellia’s actions. The fruit contains bioactive compounds including imperatorin, marmelosin, and flavonoids with demonstrated antioxidant and anti-inflammatory properties.[2]
Clinical Evidence for Respiratory Support
In a 2023 randomized, double-blind, placebo-controlled study with 105 healthy adults who reported sensitivity to air pollution, participants taking 200mg of AlvioLife daily (exactly the dose in Healthy Lungs here) experienced remarkable improvements after just 6 weeks:[3]
- 16% improvement in lung function (FEV1)
- 30% increase in lung capacity (FVC)
- 7% greater aerobic exercise capacity in the six-minute walk test
- 39% reduction in upper respiratory symptoms
- 18% improvement in psychological well-being
Even better, the benefits began appearing after just 3 weeks, with participants already showing 10% improvement in lung function and 13% improvement in lung capacity at this early stage.
An earlier clinical trial on subjects with mild to moderate asthma also demonstrated that AlvioLife significantly improved quality of life scores, with emotional function and asthma symptom scores improving in as little as 14 days compared to placebo.[4]
A respiratory support ingredient AlvioLife from PLT Health pairs Boswellia serrata with Aegle marmelos, showing 16% improved lung function and 39% fewer symptoms in clinical studies.
Advanced Mechanisms of Action
The power of AlvioLife comes from its multifaceted approach to respiratory health. Recent research has revealed that AKBA not only blocks pro-inflammatory leukotrienes but also promotes the production of anti-inflammatory compounds.[5]
AlvioLife can also inhibit human leukocyte elastase (HLE), an enzyme involved in the pathogenesis of emphysema, chronic bronchitis, and acute respiratory distress syndrome.[1] This dual inhibitory action on the inflammatory process is unique to boswellic acids and provides comprehensive support for respiratory health.
Studies also show that AlvioLife positively modulates immune markers, including increasing CD4+ T helper cells and interferon-γ while decreasing inflammatory cytokines like IL-4 and IL-8, suggesting an improved immune balance that supports healthy respiratory function.[3]
This is a very unique and interesting ingredient, and there’s more to it! For a deeper dive into AlvioLife’s mechanisms and research, check out our comprehensive AlvioLife ingredient analysis.
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Saffron Extract – 100mg
Next, Life Extension includes 100mg of saffron extract in their Healthy Lungs formula, leveraging this ancient spice’s remarkable respiratory benefits. Derived from the dried stigmas of Crocus sativus L., saffron has been treasured for millennia not just for its culinary uses but for its medicinal properties.
While we’re oftentimes used to seeing saffron in weight loss aids as an appetite suppressant (see PLT Health’s Supresa for more information on that), it can do so much more, thanks to its antioxidant properties.
Need help taming those snack attacks? Supresa is clinically validated saffron extract reduces snacking by 55% while working with your body’s natural satiety signals. No stimulants, just science backed satisfaction.
Modern research has identified several bioactive compounds in saffron that contribute to respiratory health, with the carotenoids crocin and crocetin, along with the unique compound safranal, being the primary active constituents.[6]
Clinical Evidence for Respiratory Support
Clinical studies have demonstrated saffron’s significant benefits for those with respiratory concerns. In one double-blind, randomized, placebo-controlled trial on patients with mild to moderate allergic asthma, 8 weeks of 100mg of saffron supplementation significantly improved multiple clinical symptoms, including:[7]
- Reduced frequency of shortness of breath (both day and night)
- Decreased need for rescue inhalers (salbutamol spray)
- Fewer sleep disruptions due to asthma symptoms
- Reduced activity limitations caused by breathing difficulties
Another study showed that saffron supplementation significantly improved lung function parameters, with increases in FEV1 (forced expiratory volume), FVC (forced vital capacity), and the FEV1/FVC ratio.[8]
Mechanisms of Action
Saffron’s respiratory benefits stem from several complementary mechanisms:
- Anti-inflammatory effects: Saffron significantly reduces inflammatory markers, with studies showing decreased levels of hs-CRP, IL-6, and TNF-α.[9]
- Antioxidant properties: Saffron increases total antioxidant capacity and neutralizes oxidative stress, protecting lung tissue from damage.[10]
- Bronchodilatory action: Safranal, one of saffron’s key compounds, has shown incredible bronchodilatory effects, helping to relax constricted airways.[11]
- iNOS inhibition: Research has shown that saffron inhibits inducible nitric oxide synthase (iNOS), reducing airway inflammation and hyper-responsiveness.[11] iNOS is what we consider the “bad” nitric oxide.
This multi-faceted approach makes saffron extract an ideal complement to AlvioLife in this lung/respiratory support formula.
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Andrographis Extract – 110mg
Native to South and Southeast Asia, Andrographis paniculata (commonly known as “King of Bitters”) has become one of the most promising herbal supplements for immune support and respiratory health. This traditional medicinal herb has been used for centuries in Ayurvedic, Chinese, and Thai medicine systems to treat fever, inflammation, and respiratory infections.[12]
How It Works
The primary bioactive compounds in Andrographis are diterpene lactones called andrographolides, which have demonstrated anti-inflammatory, antipyretic, antiviral, and immunostimulatory properties.[13] Andrographolide works by inhibiting pro-inflammatory pathways, reducing the production of cytokines like TNF-α and IL-6, and suppressing NF-κB activity.[14]
Benefits for Respiratory Health
Multiple randomized controlled trials have demonstrated that Andrographis significantly reduces the severity and duration of upper respiratory tract infection symptoms. A comprehensive meta-analysis involving 33 randomized controlled trials with 7,175 patients found that Andrographis provides statistically significant improvements in cough, sore throat, and overall symptoms compared to placebo.[14]
Beyond just symptom relief, Andrographis appears to shorten illness duration. Studies show it can reduce sick leave time and accelerate recovery from respiratory infections.[15]
Andrographis demonstrates an excellent safety profile at recommended doses. A systematic review and meta-analysis of safety data found that serious adverse events are extremely rare (0.02 per 1,000 patients).[16]
For those looking to strengthen their respiratory defense system naturally, Andrographis offers a science-backed option with minimal risk of side effects, and is a great way to finish this AlvioLife-powered health supplement.
Dosage and Usage
One vegetarian capsule daily, with or without food, or as recommended by a healthcare practitioner.
Breathe Easier: AlvioLife Brings Support For Healthy Lungs
With environmental challenges to respiratory health becoming increasingly common — from urban pollution and seasonal allergens to wildfire smoke and indoor air quality issues (and yes, even your lovely cats) — supporting optimal lung function has become a top priority for many health-conscious individuals. Nobody thinks about breathing until it becomes difficult to do, after all. Life Extension Healthy Lungs delivers a science-based approach with clinically-validated ingredients that address multiple aspects of respiratory wellness simultaneously.
The cornerstone of this formula is AlvioLife, with its impressive clinical data showing improvements in lung function and capacity in as little as three weeks. When combined with saffron‘s ability to relax airways and reduce inflammatory markers, along with andrographis‘ immune-modulating and protective properties, the result is a well-rounded formula that supports respiratory health from multiple angles.
Preparing for Wildfire Season?
PLT Health Solutions: Growth Through Innovation
This formula is also beneficial for those facing seasonal air quality challenges, as we know wildfire season is either here, just behind us, or coming right back up. Individuals in urban environments, those experiencing age-related respiratory changes, and anyone looking to maintain optimal breathing capacity during physical activity. The 200mg clinical dose of AlvioLife ensures you’re getting the exact amount shown to deliver significant benefits in human studies.
While no supplement can replace clean air or substitute for medical treatment when needed, Healthy Lungs provides valuable support for those looking to maintain respiratory wellness proactively. With consistent use, these ingredients work synergistically to help you breathe easier, regardless of the environmental challenges you may face.
Stay ahead of respiratory challenges and support your lung health with Life Extension Healthy Lungs. Check prices and availability with PricePlow:
Life Extension Healthy Lungs – Deals and Price Drop Alerts
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