Genius Heart & Cardiovascular Formula: Serious Ticker Support

Genius Heart Cardiovascular

Genius Heart & Cardiovascular is a supplement for EVERYONE, not just athletes, that supports heart and cardiovascular function.

Whenever The Genius Brand surfaces with a new product, you know it’s going to be an innovative, effective, and open formula. We’ve seen numerous examples of this since the brand debuted, and two of our personal favorites from the brand are Genius Joy and Genius Pre Workout.

Today, we feature the groundbreaking brand yet again with a supplement unlike any other you’ve likely used or encountered before. Unlike some of the other Genius supplements, it’s not for muscle growth, weight loss, sleep, or focus.

Genius Heart & Cardiovascular is designed to keep the engine of your body — your heart — in tip top shape for maximum health and function.

And as always with The Genius Brand, it’s full of patented or trademarked ingredients, so you’re far more likely to get the same exact, trusted ingredient in every bottle and every batch.

We’ve got more information down below, but first, take a moment to check the best deal and sign up for alerts from PricePlow:

The Genius Brand Heart & Cardiovascular Support – Deals and Price Drop Alerts

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Heart & Cardiovascular Ingredients

Genius Heart & Cardiovascular improves heart health, blood flow, and blood pressure to keep your engine running and promote superior function for the rest of your body.

Note: Doses listed below are based on one serving (i.e. two capsules).

  • Pantesin Pantethine (300mg)

    Genius Heart Cardiovascular Ingredients

    Genius Heart & Cardiovascular includes four clinically proven ingredients to boost heart health, improve blood flow, and reduce blood pressure for maximum cardiovascular health.

    Developed and distributed by Kyowa Pharma Chemical Co., Pantesin is a pharmaceutical-grade form of pantethine, better known as vitamin B5. In fact, pantethine is actually the active form of B5, making it a more direct, “effective” way to get your B5 in.

    Vitamin B5 has been studied for decades due to its effects on cardiovascular health as well as its ability to enhance activity of CoQ10 (one of the other ingredients in Genius Heart & Cardiovascular discussed below).[1] Research into the patented ingredient shows it lowers cardiovascular disease risk by decreasing LDL cholesterol by 11% compared to baseline measurements (note the placebo group saw a 3% increase in LDL cholesterol during the trial. Total cholesterol was also lower for the group receiving panethine.[2] That same study also noted increased CoQ10 enzyme activity, too.

    Another study found similar effects in regards to reducing LDL cholesterol.[3] Subjects consuming 600mg total (the same dose you’ll get with Genius Heart consuming two full servings per day) for a period of 16 weeks significantly lowered total cholesterol and LDL cholesterol more than individuals adopting a low cholesterol diet alone.[3]

    With regards to that study, realize that dietary cholesterol intake interventions often have little to do with actual cholesterol blood work — and other confines such as certain carbohydrates may play a role,[12] but the Pantesin ingredient still defeated the dietary ‘control’.

  • MegaNatural-BP Grape Seed Extract (150mg)

    Genius Heart Cardiovascular Four

    True to form, The Genius Brand is bringing only patented and trademarked ingredients backed by solid research to its formulas.

    MegaNatural-BP is new, proprietary grape seed extract made by the company Polyphenolics that’s derived from a unique seed blend of unfermented wine and juice grapes. The seeds are extracted using hot water, after which the extract is then purified, concentrated and spray dried. The end result is an extract chock full of polyphenols that serve to enhance cardiovascular health by lowering blood pressure.

    Several clinical trials have been conducted on MegaNatural-BP. In particular, one using the extract in patients diagnosed with metabolic syndrome, demonstrated blood pressure reductions averaging 12 mmHg for systolic and 8 mmHg for diastolic pressures.[4]

    A separate human trial had patients consume 300mg of MegaNatural-BP (the exact same dose included here if you consume two full servings, i.e. 4 capsules) once a day for eight weeks. Following the two month test, subjects consuming the extract experienced an average drop of 8 mmHg systolic and 5mmHg diastolic pressure.[5]

  • MicroActive CoQ10 26% (100mg)

    Genius Heart Cardiovascular Brain

    A healthy heart makes for a happy (and more productive) body and mind

    Developed by BioActives LLC and sold and distributed by MayPro, MicroActive CoQ10 is an enhanced form of supplemental CoQ10 that touts enhanced bioavailability. A common problem of most other CoQ10 supplements is their poor uptake and utilization in the body.[6]

    The geniuses at BioActives LLC solved the CoQ10 bioavailability issue by bonding each molecule of CoQ10 to beta-cyclodextrin, which improves its water solubility ensuring better transportation through your GI system and better uptake even when you’re not consuming some fats.

    Research shows that MicroActive touts 3x better absorption than crystalline (“regular”) CoQ10 and it also doubles users levels of the potent cofactor after 3 weeks.[7]

    Everyone should know about CoQ10!

    You’re probably wondering why CoQ10 is such a big deal anyway. Well, in case you’re not aware, CoQ10 is a powerful antioxidant used by virtually every cell in your body for energy production. It’s found in meat, fish, and whole grains and been heavily investigated for its benefits on cardiovascular health and athletic performance. In other words, you NEED this stuff!

  • MenaQ7 Vitamin K2 (60mcg)

    Genius Heart Cardiovascular Nitric Oxide

    Genius Heart supports greater nitric oxide production for better blood flow, leading to greater health, performance, and PUMPS

    Vitamin K2 is an essential fat-soluble vitamin crucial to bone and cardiovascular health. MenaQ7 is a trademarked form of the vitamin developed by Nattopharma that supplies an incredibly effective from of menaquinone-7 (MK-7).

    Deficiencies of Vitamin K have been associated with stiffening of the arteries, cardiovascular disease, tooth decay, and many other unpleasant things. Trials giving individuals MenaQ7 found that it reduced arterial stiffness, corrected K2 deficiencies, and improves bone health.[8,9,10,11]


Consume 1 capsule twice daily with a meal.

A unique take on heart health supplements

Genius Logo

The Genius Brand is a new company dedicated to providing high-quality, clinically dosed products using research-backed ingredients. Click the image to see all Genius Supps!

No joke, The Genius Brand is shaking up formulations in every category in the industry. For instance, Genius Joy is a mood booster unlike anything out there, and Genius Burn is a new way to get focused on your diet without stimulants.

PricePlow often writes articles about products for athletes, but this brand is too interesting to miss. Genius Heart & Cardiovascular is for everyone – especially high-risk individuals (who, of course, should only use this under the expressed written consent of their doctors).

On the athletic side, it’s far too often that athletes and lifters are concerned with improving their performance, but neglect things like joint, cardiovascular, and cognitive function. The Genius Brand aims to enhance all aspects of an individual (not just athletes) with their incredibly diverse range of supplements. Genius Heart supports your ticker to enable you to perform better in the gym or on the field… or simply in life in general.

The Genius Brand Heart & Cardiovascular Support – Deals and Price Drop Alerts

Get Price Alerts

No spam, no scams.

Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer.

Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public.

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  1. Gaddi, A., et al., Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia. Atherosclerosis, 1984. 50(1): p. 73-83.
  2. Evans M, Rumberger JA, Azumano I, Napolitano JJ, Citrolo D, Kamiya T. Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation. Vasc Health Risk Manag. 2014 Feb 27;10:89-100. doi: 10.2147/VHRM.S57116. eCollection 2014.
  3. Rumberger JA, Napolitano J, Azumano I, Kamiya T, Evans M. Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation. Nutr Res. 2011 Aug;31(8):608-15. doi: 10.1016/j.nutres.2011.08.001.
  4. Park, E., Edirisinghe, I., Choy, Y., Waterhouse, A., & Burton-Freeman, B. (2016). Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: A randomised, double-blinded, two-arm, parallel, placebo-controlled trial. British Journal of Nutrition, 115(2), 226-238. doi:10.1017/S0007114515004328
  5. Robinson M, Lu B, Kappagoda T., Effect of Grape Seed Extract on Blood Pressure in Subjects with Pre-Hypertension. Journal of Pharmacy and Nutrition Sciences, 2012, 2, 155-159.
  6. Bhagavan HN, Chopra RK. Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006;40(5):445-453. doi:10.1080/10715760600617843.
  7. Madhavi D, Kagan D. A Study on the Bioavailability of a Sustained-release Coenzyme Q 10 -β-Cyclodextrin Complex. 2010;9(1):20-24.
  8. Mansour AG et al. Vitamin K2 supplementation and arterial stiffness among renal transplant recipients – a single-arm, single-center clinical trial. J Am Soc Hypertens. 2017 Jul 13. Pii: S1933-1711(17)30255-3.
  9. Knapen MHJ, Braam LAJLM, Drummen NE, Bekers O, Hoeks APG, Vermeer C. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost. 2015;113(5):1135-1144. doi:10.1160/TH14-08-0675.
  10. Theuwissen E, Cranenburg EC, Knapen MH, et al. Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects. Br J Nutr. 2012;108(9):1652-1657. doi:10.1017/S0007114511007185.
  11. van Summeren MJH, Braam LAJLM, Lilien MR, Schurgers LJ, Kuis W, Vermeer C. The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. Br J Nutr. 2009;102(8):1171-1178. doi:10.1017/S0007114509382100.

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