Some companies seem to release a new product every month of every year just to stay in the forefront of everyone’s mind. Others take their time, maybe release 2-3 products per year, stay under the radar and let their products speak for themselves.
ANS Performance is the latter, so when a company like ANS releases a new product, it’s time to take notice.
They’ve now developed a brand new thermogenic fat-burner called Diablo Inferno, the hard-hitting follow-up to their original Diablo fat burner that hits all the right notes when it comes to more extreme lipocyte incineration.
Long story short
- Upgrade to Diablo: More aggressive on the thermogenic heat ingredients
- Proprietary blend: Higher than average caffeine but not disclosed
- New ingredients to see: AdiLase™ and eLMn8™
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Diablo Inferno Ingredients
Although we’re not fortunate enough to have a completely open label, ANS does include a whole host of proven fat burning and metabolic boosting ingredients in Diablo Inferno, and they’ve told us how much caffeine is in each capsule:
Diablo Inferno Complex (435mg)
Caffeine is the backbone of any fat burner worth the capsule it’s packaged in. It’s the most popular drug on the planet with a whole host benefits whether you’re looking to increase performance or boost your metabolism.
Too little and you won’t feeling anything. Too much, and you’ll feel jittery and probably have trouble sleeping, in addition to declined performance.[1,2] However, the right amount can increase your awareness, stamina, and fat-burning ability.[3,4,5]
It’s not on the label, but this formula is rumored to have a relatively high caffeine dose, especially when adding the other stims like Theacrine below.
This is why there’s a maximum of two caps per day.
As strong as two servings of the powder?
In fact, ANS is saying that Diablo Inferno has roughly the thermogenic strength of two scoops of the powder.
We hope ANS will choose to share the dose in the formula, but for now, let’s suspect that it’s greater than the standard 150/175mg doses we often see, and definitely higher than the lower-stim 100mg caps out there.
But hopefully it’s not too high… because we have several other ingredients left in the 435mg blend.
Higenamine, a.k.a. Norcoclaurine, is a beta agonist in the body that exerts and mild stimulatory effect, similar to other beta agonists, and as such has been referred to as the “weaker ephedrine.”
When paired with caffeine, and the host of stims to come, higenamine really shines. Higenamine increases the body’s production of noradrenaline, which drives the “fight or flight” response you feel in times of stress. Often times, this results in heightened focus and concentration as well as mobilizing stored fats for energy!
There seems to be an ongoing and unspoken “higenamine vs. synephrine” battle – the two stimulants work similarly. Synephrine’s been making a comeback, but we personally seem to get a better “feel” from the higenamine here.
Choline is a compound predominantly found in egg yolks and forms the backbone of the neurotransmitter acetylcholine in the body, a.k.a “the learning neurotransmitter.” Usually, choline supplements are used to improve focus and cognition during your workouts as well as the mind-muscle connection.
However, some interesting research shows that choline can actually help weight loss as well. A 2014 study on Tae Kwon Do athletes found that choline supplementation was able to help rapidly drop weight without any loss of strength. Note that the dose of choline used was far higher than what can be in here, though.
So, not only will you be feeling more “in the zone” while taking Diablo Inferno, you could possibly get a pleasant boost in weight loss as well – depending on the dose. Taking more choline is always a fine idea if you like it for focus.
Hordenine is one of several alkaloids found in Citrus Aurantium, a.k.a. bitter orange. Much like Synephrine and Octopamine (the other alkaloids in bitter orange), hordenine also operates as a beta-2 adrenergic agonist.
Furthermore, Hordenine also functions as a noradrenaline reuptake modulator in the body.[9,10] Basically this means hordenines helps noradrenaline stay around longer in your system, which leads to greater focus, energy, and alertness.
This is yet another feel-good ingredient that’s great to be paired with the other stimulants and cognitive boosters.
Evodia rutaecarpa is a Chinese berry that’s traditionally been used as a thermogenic to keep people warm. ANS has included the 98% standardization evodiamine in Diablo Inferno.
Evodiamine mimics capsaicin’s (red hot pepper extract) actions in the body by stimulating the vanilloids in your body, which helps reduce fat uptake by cells.[12,13]
It also suppresses circulating levels of caffeine in the body.[14,15] This helps smooth out caffeine’s effects and eliminate any “jitters” you may feeling taking high doses of stimulants. Lastly, evodiamine also functions as a mental booster helping to improve cognition.
But truth be told, evodiamine is all about the thermogenesis from heat – something “Diablo Inferno” is clearly trying to
Green Coffee Bean Extract
Of all the great ingredients included in Diablo Inferno, we have a weight loss dud in Green Coffee Bean Extract (GCBE). The “successful” studies proclaiming it a wonder weight loss ingredient were based on shady research that since has been retracted. This was due to the fact that the trials were heavily biased by supplement manufacturers and confounded with other ingredients that were already proven weight loss ingredients.
However, GCBE is high in chlorogenic acid, which is great for the heart and can lower blood pressure, but there’s no established link between this ingredient and fat loss.
Chalk this one up to marketing towards the Dr. Oz crowd (are they still searching for this ingredient?!)
AdiLase™ is patented, specialized extract of Hemerocallis fulva, exclusive to ANS. This ingredients is just beginning to show up in fat burners. It is extracted from the Orange Day Lily found predominantly in Asia.
Studies on the extract demonstrate it enhances lipolysis in animals, especially when paired with noradrenaline. It’s also been suggested that it could prevent the accumulation of future fat stores on the body as well
Alongside the other ingredients that increase noradrenaline levels in Diablo Inferno, the addition of Hemerocallis fulva should be boost in fat burning rarely seen with other products.
eLMn8™ is an extract of Alchemilla vulgaris, an herbaceous perennial plant in Europe and Greenland commonly referred to as Lady’s Mantle. Extracts of the plant contain high levels of various tannins that are able to increase metabolism, suppress appetite, and reduce caloric intake.
All of this adds up to a unique new ingredient that can shed weight when you’re having problems making the scale move.
Theacrine is a compound similar to caffeine and possesses many of the same benefits when consumed. The big difference between the two is that theacrine doesn’t have a tolerance build up like caffeine does.
This means that you won’t need to continually increase the dose to keep seeing the same effects of theacrine. Additionally, theacrine reduces oxidative stress in the body when used for at least seven days consecutively, and increasesdopamine levels in the brain, also seen with caffeine.
Adding this to the higher-than-average caffeine dose is pretty aggressive — this is going to make it last longer with less crash, but it’s also going to add to the hit that the caffeine gives you.
Typically L-Carnitine L-Tartrate (LCLT) supplements are used to help conserve muscle mass and speed recovery during workouts. However, this highly bioavailable form of L-Carnitine has been shown to increase a phenomenon known as “Fatty acid dumping.”
Here, fatty acids are excreted in the urine in the form of acylcarnitine and acetylcarnitine. What’s really interesting is that this phenomena is dramatically increased when used alongside choline and caffeine (both included in Diablo Inferno).
Olive Leaf Extract
Olive Leaf Extracts have widely been used as an all-natural thyroid hormone booster. Research using the extracts demonstrate that even minimal doses are effective at increasing thyroid levels.
The real benefit to olive leaf extract is its high oleuropein content. It helps to lower cholesterol as well as regulate blood pressure and glucose levels.[28,29,30]
6AM™ is the third proprietary extract included in Diablo Inferno. 6AM™ comes from Aframomum melegueta also known as “Grains of Paradise”. Clinical trials utilizing the extract found it significantly increases energy expenditure and loss of brown adipose (fat) tissue.[25,26]
Higher energy expenditure increases the amount of calories you burn each day, resulting in a marked reduction in visceral fat and overall weight loss.
Between this and the evodiamine (and the stims, of course), the thermogenic heat from Diablo Inferno is likely going to live up to its name. This ingredient definitely provides a warming sensation!
Start by taking 1 capsule in the morning with a glass of water for the first 2-3 days to assess tolerance. Once you’ve got a feel for how you respond, you can then proceed to consume 1 capsule in the morning, and 1 capsule again in the afternoon.
Per ANS’ recommendations, DO NOT exceed 1 capsule per serving, and DO NOT exceed 2 capsules in a 24-hour period. If you’re overly-sensitive to stims, do not take within 5 hours of bedtime to avoid sleeplessness.
Fat burners are one of the most over crowded categories on the market. Most of the offerings out there are little more than a serious overload of caffeine (which this one seems to have), with little in the way of true lipolytic action. Diablo Inferno is one of the exceptions that will boost your energy, metabolism, and mood all without sending you too far through the roof… but a good stimulant tolerance is needed here!
Should you need a little extra help shedding those holiday pounds this year, and you like a more serious dose of caffeine along with some heat, make sure to give Diablo Inferno a try!
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- Pasman, W; The effect of different dosages of caffeine on endurance performance time.; Department of Human Biology, University of Limburg; 1995
- Desbrow, B; The effects of different doses of caffeine on endurance cycling time trial performance.; School of Public Health, Research Centre for Clinical and Community Practice Innovation, Griffith Health Institute, Griffith University; 2012
- Bolton S., Null G.; Orthomolecular Psychiatry; “Caffeine: Psychological Effects, Use and Abuse;” 1981
- Kovacs, B; MedicineNet.com; “Caffeine;” 2013
- Westerterp-Plantenga, MS, et. al; Obesity Research; “Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation;” July 2005
- Frank M, et al; Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse; Equine Vet J. (1990)
- Barwell C.; School of Pharmacy; “Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat;” 1989
- Nedergaard O.; British Journal of Pharmacology; “Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig;” November 1968
- Pearce LV, et al; Evodiamine functions as an agonist for the vanilloid receptor TRPV1 . Org Biomol Chem. (2004)
- Noh K, et al; Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats . Arch Pharm Res. (2011)
- Tsai TH, Chang CH, Lin LC Effects of Evodia rutaecarpa and rutaecarpine on the pharmacokinetics of caffeine in rats . Planta Med. (2005)
- Watanabe, T; The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension.; Health Care Products Laboratories, Kao Corporation; 2006
- Cauli, O;Subchronic caffeine exposure induces sensitization to caffeine and cross-sensitization to amphetamine ipsilateral turning behavior independent from dopamine release.; Department of Toxicology and Centre of Excellence for Neurobiology of Dependence, University of Cagliari; 2008
- Li WX, et al.; “Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice.“; J Agric Food Chem.; 2013
- Feduccia A, et al.; “Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors.”; Pharmacol Biochem Behav; 2012
- Sachan DS, Hongu N; Increases in VO2max and metabolic markers of fat oxidation by caffeine, carnitine, and choline supplementation in rats . J Nutr Biochem. (2000)