For health-conscious adults seeking to maintain their vitality and active lifestyle as they age, understanding the role of nitric oxide (NO) in the body has become increasingly important. Often referred to as the “miracle molecule” in published research,[1,2] nitric oxide plays a crucial role in supporting cardiovascular health, cognitive function, and overall well-being.
As the science behind nitric oxide continues to advance, Nutrition21’s Nitrosigine® has emerged as The Superior Nitric Oxide Booster, offering a breakthrough option for those looking to support their body’s NO production effectively.
Understanding Nitric Oxide’s Critical Role in Health
Nitric oxide is a signaling molecule produced naturally within the body that serves as a key messenger in various physiological processes.[3] Its primary function involves promoting vasodilation – the relaxation of blood vessels that allows for optimal blood flow throughout the body.[4]
Through this mechanism, nitric oxide supports cardiovascular health and circulation while facilitating the delivery of oxygen and nutrients to working muscles.[4] Beyond its vascular effects, nitric oxide plays a vital role in supporting cognitive function and brain health,[5] promoting men’s sexual health and vitality,[6] and supporting overall cellular energy production throughout the body.[7]
The Challenge: Declining NO Production with Age
As we age, our body’s ability to produce nitric oxide naturally declines – a change that typically begins in our thirties. Research indicates that by age 40-50, we may produce only half the nitric oxide we did in early adulthood.[8,9] This significant decrease can impact various aspects of health and vitality. Reduced nitric oxide levels can affect blood flow,[10] impacting the circulatory system and potentially influencing physical performance and recovery. Given the important role of NO, a natural decline in production may even affect cognitive performance and perceived energy levels.
Furthermore, factors such as poor diet, sedentary lifestyle, and various health conditions can compound this decline, making it even more challenging for the body to maintain optimal nitric oxide levels.[11]
This creates a pressing need for effective practices and ingredients to support healthy NO production as we age. Nutrition21 has the industry-leading answer:
Nitrosigine®: A Superior Solution for NO Support
Nitrosigine, a patented complex of bonded arginine silicate,[12,13] provides a unique and bioavailable form of arginine – the most important precursor nutrient the body uses to produce nitric oxide. While traditional L-arginine supplements have shown limited effectiveness due to poor bioavailability,[14-17] Nitrosigine offers several distinct advantages:[18-24]
- Enhanced bioavailability compared to standard L-arginine
- Rapid absorption (within 30 minutes)
- Sustained elevation of blood arginine levels for up to 6 hours
- Effective at a lower dose (1.5 grams) compared to other NO boosters like citrulline
Clinical Evidence: Improved Flow-Mediated Dilation
A landmark study published in the Journal of the International Society of Sports Nutrition demonstrated Nitrosigine’s superior efficacy using flow-mediated dilation (FMD) – the gold standard method for measuring nitric oxide-dependent vascular function. The research showed that a single 1.5-gram dose of Nitrosigine significantly increased vasodilation by nearly 25% compared to baseline, outperforming the placebo group (increased by 0.60%).[20]
This improvement in FMD response indicates Nitrosigine’s ability to effectively boost nitric oxide production and support healthy blood flow – achieving these results at just one-fifth the dose of comparable ingredients. These findings underscore why Nitrosigine has earned its position as The Superior Nitric Oxide Booster.
Comprehensive Benefits for Healthy Aging
By supporting the body’s nitric oxide production, Nitrosigine delivers a comprehensive range of benefits. For cardiovascular health, it supports healthy blood flow and circulation while helping maintain flexible, healthy blood vessels. This improved circulation promotes optimal nutrient delivery throughout the body, supporting overall cardiovascular function.
In terms of physical performance, Nitrosigine enhances oxygen and nutrient delivery to working muscles during activity. This support helps maintain energy levels and vitality, allowing adults to stay active and energetic throughout their day. This is evidenced by a recent study showing that Nitrosigine enhances blood flow to working muscles (as measured by increased hyperemia) and increases perceived energy levels when taken over multiple days.[21]
Cognitive function also benefits from Nitrosigine’s NO-boosting effects.[22-24] By supporting healthy blood flow to the brain, it promotes mental sharpness and focus while helping maintain cognitive performance. This cognitive support becomes increasingly important as we age and seek to maintain our mental acuity.
The overall impact on vitality can be quite substantial. Nitrosigine helps support natural energy levels through improved circulation throughout the body, promoting the maintenance of an active lifestyle and helping adults feel their best at any age.
Nitrosigine: The Superior Choice for Nitric Oxide Support
Over the years, we’ve covered Nitrosigine numerous times, often in workout supplements. Fueled by its early success in athletic applications, Nutrition21 is taking its flagship ingredient to greater heights and a broader consumer base, giving it a new slogan of “The Superior Nitric Oxide Booster” in 2024.
As a clinically-studied, patented ingredient, Nitrosigine represents the next generation in nitric oxide support. Its unique formulation provides superior bioavailability and effectiveness at a lower dose than traditional options, making it an ideal choice for health-conscious adults looking to support their vitality and maintain an active lifestyle as they age.
Supported by multiple clinical studies and protected by patents, Nitrosigine offers a safe, effective way to promote healthy nitric oxide production and support overall well-being. For those seeking to maintain their vitality and support healthy aging, Nitrosigine stands as the superior solution for enhancing nitric oxide production and promoting optimal health.
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