Athletics are usually dominated by those who are bigger, faster, and stronger than the competition. However, to succeed in the business and academic worlds, it’s often those who are the strongest and most productive mentally that take home the big pay day.
Due to this, the use and study of nootropics has exploded in recent years by those looking to get a mental leg up on the competition. Sure, you’ve maybe tried some basic cognitive enhancers, but nothing like what we have in store for you today.
OmniMind takes things to the next level. The magic behind it lies in its ability to enhance long term potentiation (LTP).
LTP is defined as “a persistent strengthening of synapses based on recent patterns of activity.” In layman’s terms you create a long-lasting enhancement of the signal transmission between neurons. This can lead to better all around memory formation, storage, and retrieval.
Where to find it
OmniMind isn’t listed in any PricePlow price comparisons, but you can see it directly on their website at GetOmniMind.com.
But first, read through our ingredient analysis to see the research behind the artichoke extract and other nootropic compounds:
OmniMind’s label is a rarity in the mental productivity booster market. Most times, we see bloated prop blends of varying amalgamations of nootropics and stimulants. Here, however, you have a fully transparent label that details how much of each ingredient is included in each serving.
Additionally, don’t think this is your same old, same old everyday assortment of mental enhancers. There are plenty of familiar faces in OmniMind, but there’s also quite a few surprises as well!
Note: Doses listed below are for 3 capsules (one full serving).
Artichoke Extract (Cynara Scolymus) [1000mg]
Artichoke extract?! Really?
Yes, OmniMind’s first ingredient and most by weight is an extract from the famous bulb vegetable. This is really why we’re excited about this nootropic – we love promising new ingredients and are always looking for new research behind them.
LTP enhancement works off a particular combination of ingredients, the first of which is a Phosphodiesterase 4 (PDE-4) inhibitor.
It just so happens that artichoke extract is a rich source of Luteolin, a safe and all-natural inhibitor of PDE-4. The reason we want to block PDE-4 is that it (PDE-4) blocks cAMP, a powerful intracellular molecules that relay signals in the brain.
So, by blocking the compounds that can block signal relay, we’re effectively enhancing signal transmission in the brain. This leads to heightened focus, optimal brain function, and better long-term memory.
Seems worth a try… and leads us to wonder if there might be some workout enhancement for the athletes here as well!
Phenylalanine is an essential amino acid used by the body in the production of tyrosine, and the second part of the LTP equation. Following this conversion, the body uses tyrosine to synthesize several important “feel good” chemicals in the brain including epinephrine, norepinephrine, and dopamine.
As a dopamine enhancer, phenylalanine helps give users a slight euphoric feeling. Due to this, it’s no wonder, this amino acid has been used in the treatment of diseases such as depression.
Forslean™ Forskolin [250mg]
We’ve covered the first two components of LTP, now it’s time to address our final component of the equation, cAMP maximization!
Remember that the artichoke extract is inhibiting PDE-4, which frees up the normal amount of cAMP usually present. The body can actually get even more cAMP by supplementing with Forskolin.[6,7] This, once again, can lead to more focus and memory[24,25] – and it makes great sense, even though we’ve never seen forskolin marketed in this fashion (see below).
Also great for weight loss!
As an added bonus, Forskolin is also great when it comes to preserving lean muscle mass while losing weight![8,9] This is how we typically see forskolin marketed, but increased levels of cAMP do more than burn more fat — the process gets the brain moving faster too, and could responsible for both a better focus and memory because of it.
So that’s why it’s here in OmniMind… but we won’t complain about burning some extra fat either.
Caffeine Anhydrous [150mg]
Caffeine really needs no introduction or explanation. It’s the most studied and used supplement of all time and its benefits go on and on and on. In the body, it acts as a potent stimulant of the central nervous system (CNS) that helps to increase energy and alertness.[10,11].
There’s plenty more though, caffeine also reduces fatigue, improves short-term memory, and enhances problem solving ability. It’s hard to imagine how included a moderate dose of this wouldn’t benefit you in some way. Including it in OmniMind really helps bolster the other nootropics included.
Those of you that get a little edgy or jittery even from moderate amounts of caffeine, pay attention, this ingredient is for you! Theanine is an amino acid predominantly found in tea leaves that helps to smooth out the harsh stimulant kick of caffeine.
Additionally, Theanine also improves the cognitive focus effects of caffeine, and helps alleviate stress, anxiety and fatigue.[14,15] This ingredient has become a favorite of Mike’s and has been showing up in a number of our Top Pre Workouts as of late.
Tyrosine supplements are one of the most frequently used compounds for improving memory and cognition. It boosts the production of two big-time neurotransmitters in the body, dopamine and noradrenaline. Elevated levels of these neurotransmitters increase overall mood and focus, while simultaneously reducing symptoms of stress and anxiety.[16,17]
Acetyl L-Carnitine [100mg]
Acetyl L-Carnitine (ALCAR) is a unique form of the amino acid L-Carnitine than has the ability to cross the blood-brain barrier. ALCAR can reduce mental fatigue, improve mood, and boost Nitric Oxide levels.
One last nugget of knowledge is that ALCAR works synergistically with caffeine to increase “fatty acid dumping”, a condition where fatty acids are excreted by the body when its cells are engaged in fat burning.
Note that we’ve definitely seen larger doses of L-Tyrosine and ALCAR, but these are merely supporting ingredients for the star players listed above with higher doses. You can add more of these relatively cheaply if you know you’re a big fan of them (and we suggest doing so after running OmniMind standalone first).
Essential Vitamins & Minerals
In addition to all the nootropic boosters and cognitive enhancers in OmniMind, the developers have also included several essential vitamins and minerals required by the body for optimal functioning of the brain and energy production systems of the body. Included are:
- Iron [14mg]
- Vitamin B3 (nicotinamide) [6mg]
- Vitamin B6 (pyridoxine hydrochloride) [4.2mg]
- Vitamin B5 (calcium-d-pantothenate) [3mg]
- Zinc [3mg]
OmniMind is a once-daily regimen. Take three capsules just once per day alongside of breakfast.
Note that there’s 150mg caffeine here, so you may need to ditch the morning coffee routine if you have one – or move down to a small half-cup (say 4oz) just to get the warmth in.
The concept of Long Term Potentiation (LTP) may seem a little far out there for some of you, but as the saying goes, “don’t knock it till you try it.” Artichokes are underrated fat and antioxidant sources, and there’s some pretty interesting research to back it up, so this is something a nootropic fan has to check out at some point!
A quick search on Google shows that LTP is a major topic of discussion on several prominent nootropic-centered websites and message boards.
While it may not give you the powers Bradley Cooper had in Limitless, any means of enhancing your mental processing speed, learning capacity, and memory (both short and long term) should be of interest to everyone. In an era of increasing neurodegenerative mental diseases, all-natural supplements that can counteract any deleterious mental effects of aging is a huge win in our book!
OmniMind is a comprehensive product that enhances all aspects of the brain’s unlimited power, and it’s got a hot new ingredient we want to try. So whether you’re reaching the top levels in sports, academics or business, OmniMind gives you the mental clarity and determined focus to get the job done successfully. One of these supplements you don’t want to share with your direct competition.
Where to find it
You can find it directly on their website at GetOmniMind.com. We’ll see if it ever comes to any of PricePlow’s stores in the meantime.
Like this Post? We have more on the way...
PricePlow is a price comparison site that asks one simple question: is this worth it?
The honest truth lives here. Follow us on social media below:
- Houslay MD, Adams DR. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochemical Journal. 2003;370(Pt 1):1-18. doi:10.1042/BJ20021698.
- Bei Xu, et al. Luteolin promotes long-term potentiation and improves cognitive functions in chronic cerebral hypoperfused rats . European Journal of Pharmacology Volume 627, Issues 1–3, 10 February 2010, Pages 99–105
- Roise, J. et al. (2005). The Subjective and Cognitive Effects of Acute Phenylalanine and Tyrosine Depletion in Patients Recovered from Depression. Neuropsychopharmacology. Volume 30, Issue 4. (pp. 775-85)
- Bristow, M. R., R. Ginsburg, W. M. Strosberg & W. (1984) Minobe: Pharmacology and inotropic potential of forskolin in the human heart. J. Clin. Invest., 74, 212-223. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC425203/
- Alasbahi, R. H., & Melzig, M. F. (2012). Forskolin and derivatives as tools for studying the role of cAMP. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 67(1), 5-13. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22393824
- Godard MP, Johnson BA, Richmond SR. (2005) Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res, 13(8):1335-43. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16129715
- Srivasta SK, Khatoon CS, Mehrotra SR (2002). Pharmacognostic evaluation of coleus forskohlii. Pharmaceutical Biology 40, 129-134. Retrieved from http://www.tandfonline.com/doi/abs/10.1076/phbi.126.96.36.19942
- Zwyghuizen-Doorenbos A e.(1990) Effects of caffeine on alertness. Psychopharmacology (Berl). 1990;100(1):36-9.
- Smith A. Effects of caffeine on human behavior. Food Chem Toxicol. 2002;40(9):1243-1255.
- Glade, M. (2010). Caffeine—Not just a stimulant. Nutrition, 26(10), 932-938. doi:10.1016/j.nut.2010.08.004
- Giesbrecht, Timo, et al; “The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness”; Nutritional Neuroscience; 2010
- Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. (2007)
- Owen GN, et al. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. (2008)
- Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
- Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
- Vermeulen RC, Scholte HR; Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome . Psychosom Med. (2004)
- Parnetti L, et al; Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type . Eur J Clin Pharmacol. (1992)
- Soczynska JK, et al; Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders . Expert Opin Investig Drugs. (2008)
- Bloomer RJ, Tschume LC, Smith WA; Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects . Int J Vitam Nutr Res. (2009)
- Sachan DS, Hongu N; Increases in VO2max and metabolic markers of fat oxidation by caffeine, carnitine, and choline supplementation in rats . J Nutr Biochem. (2000)
- Vauzour, David et al. “The Neuroprotective Potential of Flavonoids: A Multiplicity of Effects.” Genes & Nutrition 3.3-4 (2008): 115–126; Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593006/
- PW, L. Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus. Neuroscience. 1999 Jan;88(1):69-78.
- Otmakhov, N. (2004). Forskolin-Induced LTP in the CA1 Hippocampal Region Is NMDA Receptor Dependent. Journal Of Neurophysiology, 91(5), 1955-1962. doi:10.1152/jn.00941.2003