PES ERGONINE – The Once-Per-Day Muscle Supplement

DISCONTINUATION NOTICE: This supplement was discontinued and is now out of stock. We’re leaving this article up because we loved the product so much.

Can one supplement handle all of your muscle-building needs at just $1/day? See what we think about Ergonine below

PES Ergonine is the workout enthusiast’s “one-a-day” supplement promised to take care of all of your basic needs in regards to enhancing performance and building muscle.

Rather than opening 9 different tubs or combining multiple pills, powders, and other potions to cover all your bases, PEScience has taken the complication and hassle out of the equation; bringing everything you need in 1 all-encompassing tasty scoop.

Originally launched under the brand Athletix (which was acquired by PEScience), a no-fuss, direct-to-user supplement vendor with no-middleman to markup the price, Ergonine has been moved back to the PES product line.

Ergonine’s proposed benefits include:

• Increases in lean body mass
• Reduced fatigue
• Enhanced recovery

The key word here is “ergogenic” — this is a product geared towards muscle building.

What’s in it and are these ingredients really proven to work?Is it truly a $1/day catch-all supplement worth investing in? Let’s find out below as we delve into the ingredient list!

PES Ergonine Ingredients

• Creatine Anhydrous (3g)

  

  The ingredients / supplement facts

  We all know what creatine is by now, it’s one of the foundational bodybuilding supplements with countless studies to prove it’s benefits in regards to:

  • Increased Power and Strength^[1,2]
  • Lean Mass / Body Composition^[3-5]
  • Cell Hydration^[6]
  • Reduced Fatigue^[7]

  PEScience breaks away from the tried and true creatine monohydrate or Creatine HCl and uses a novel form that is 100% pure, unadulterated creatine. Creatine anhydrous contains 12% more creatine by weight than creatine mono does.^[8]

  What about the dosage?

  Research has shown that the efficacious dosage of creatine is 3-5g per day and we get 3g of 100% pure creatine. Looks like Ergonine is 1 for 1 – Good start!

• Betaine Anhydrous (2.5g)

  

  Image Egregiously Stolen from PES

  Betaine, aka trimethylglycine, is an the amino acid glycine with 3 methyl groups bonded (tri-methyl) to it. Betaine is a great partner to creatine and provides many of the same benefits when the two are paired together:

  • Increased Power Output^[9]
  • Reduced Soreness^[10]
  • Cell Hydration^[11]
  • Cortisol Level Reduction^[12]

  What about the dosage?

  The dosage administered in all of the studies on betaine indicated 2.5g was needed to reap the research-backed benefits of its supplementation.As you can see, PEScience has used that exact amount in Ergonine.2 ingredients down, 7 more to go!

• SynerGlut Blend (2.5g)

  Ergonine’s SynerGlut Blend is a combination of 2 amino acids, L-Alanine and L-Glutamine.Now, you may be wondering why are these two paired together?

  Glutamine is well-known to have muscle recovery benefits^[13], but the problem is when taken alone, it is completely absorbed in the stomach and never makes its way to the muscle tissue. Enter Alanine!!!

  Research has shown that when Glutamine is consumed in tandem with Alanine, Glutamine makes its way to your muscle cells supplying the much needed recovery benefits your body needs after each and every training session.^[14,15]

  What about the dosage?

  The studies used a dosage varying between 1g – 2g of the Glutamine/Alanine combo. There was no significant difference in the outcomes between the 1g dose and the 2g dose. PES appears to be going the safer route here and going on the higher end for dosing, thus ensuring maximum absorption is achieved.

• L-Carnitine-L-Tartrate (LCLT) (2g)

  

  LCLT is the form of L-Carnitine that you want if you’re into building muscle

  Similar to L-Glutamine, the mythos of the bodybuilding world have long touted the benefits of L-Carnitine supplementation.However, studies on pure L-carnitine supplementation continually showed no results unless you’re carnitine deficient (which is primarily reserved for vegetarians and the elderly).

  But enter the L-Carnitine-L-Tartrate (LCLT) form and things change.

  When administered is a 2g dose, LCLT supplementation demonstrated:

  • Increased Fat Oxidation^[16,17]
  • Improved Recovery^[18]
  • Reduced Soreness^[19]

  What about the dosage?

  Ergonine comes fully loaded with the clinically backed 2g dosage of LCLT, so no need to go buying a tub to top off your needs for carnitine supplementation.

• Hydroxy-Isocaproic Acid (HICA) (1.5g)

  

  PES’ Alphamine, which we currently rank as the best fat burner, is one of the few weight loss products to include HICA

  HICA, also known as Leucic Acid, is a metabolite of the BCAA Leucine. Leucine is the most studied of the BCAAs and provides the catalyst for the mTOR pathway in the body. This is crucial because the mTOR pathway stimulates muscle protein systhesis, so…no leucine, no muscle-building.

  HICA supplementation has been noted to provide numerous benefits including:

  • Increased Lean Mass^[20]
  • Improved Performance^[20]
  • Reduced Soreness^[20]
  • Decreased Fat Mass^[20]

  What about the dosage?

  The dosage required to extoll the numerous benefits of HICA was 1.5g. PES doesn’t cut any corners again and includes a full 1.5g clinically-backed dose in Ergonine.

• PerformaLean Blend (1.1g)

  Ergonine’s PerformaLean Blend is comprised of a proprietary blend of Choline Bitartrate, Glycerol 65% (HydroMAX), and Ferula Asafoetida (Root) Extract (95% Ferulic Acid).

  This is primarily a support blend for the other ingredients (for instance, the choline boosts the carnitine).

  Let’s look at the primary and secondary benefits of each one:

  • Choline Bitartrate

    Choline has long been touted for its benefits in improving mood and focus during workouts, but it also offers so much more! Choline has been shown to aid in fat loss and exercise endurance.^[21,22]

    But the real reason it’s here is because it’s been shown to increase the muscle’s absorption of carnitine!^[23]

    Furthermore, strenuous and repeated bouts of exercise deplete the body of its choline stores and reducing the amount of neurotransmitters circulating in the body. This leads to a decline in mood, energy, and focus. So, to keep bringing it everyday in the gym, you’re going to want to be topping of your choline reserves daily!

  • Glycerol 65% (HydroMAX)

    

    We LOVE this ingredient

    Glycerol has long been known as a key ingredient in many of the “pump” products on the market. The main reason it’s here, however, is to provide for fluid balance in your system.

    The problem is, most other products use glycerol monostearate (GMS), which is glycerol attached to a bunch of saturated fatty acid chains. You’ll notice these as those pesky clumps that never seem to dissolve in your shaker bottle…

    Ergonine instead uses HydroMAX which is 65% glycerol by weight, while GMS is roughly ¼ glycerol by weight. This also solves the problem of those clumps in your pre-workout and makes for easy dissolving.

  • Ferula Asafoetida (Root) Extract (95% Ferulic Acid)

    Ferulic Acid is a relative newcomer to the supplement world and more than likely hasn’t been included in any supplement you’ve tried before.PEScience opted to include this novel ingredient in Ergonine because research has shown that in as little as 30mg/day, there were noticeable improvements in recovery, strength, endurance, and muscle mass!^[24,25]

  What about the dosage?

  Seeing that this is a proprietary blend, we have no way of knowing if Ergonine contains the efficacious doses of these 3 ingredients. Based on all of the other ingredients being dosed at clinically proven levels, leads us to believe that PES won’t short change us here, but as always buyer beware of proprietary blends.

  We’ll just say this: with choline on top of of a three-ingredient blend at 1.1g, that means you’re getting a minimum of 367mg choline. That’s more than a lot of “focus” supplements use, and this isn’t even marketed towards that!

Available Flavors

So far in early 2015… (see the PricePlow widgets above and below to have an updated list)

• Blue Ice
• Nanaberry (an amalgamation of banana and strawberry!)

Recommended Dosage:

On training days, mix 1 scoop in 10-12 oz of water and consume 30-60 minutes prior to exercise.This is within the timeframe you’ll be guzzling your pre-workout anyway, so what’s one more powder to throw in the old shaker bottle?!

On non-training days, take your serving in the morning with or without food

The General Consensus / Pre-Review

In one word: Finally!

PES promised a $1/day supplement to take care of all of your basic needs as an exercise enthusiast. It’s retailing for $29.99 for a 30 serving tub and should you choose to buy more than one, there are some volume discounts.

On the surface, it appears Ergonine will be a worthwhile addition to your supplement stack as it uses scientifically proven ingredients dosed in research-backed amounts.Seeing as it’s just released, there aren’t any substantial reviews to validate its effectiveness, but it goes without saying that this is going to work well for nearly everyone.

Cover the gap that your other supplements don’t

With tons and tons of underdosed pre workouts out there (we rant about this in our recent “Creatine is Broken” article), this is the product that will cover your gaps – on workout days and off days – once and for all!

Time will tell, but the arrow is pointing up and you can be sure once we’ve had the chance to test it out, we’ll have our thoughts posted up ASAP!

Where to buy Ergonine

Ergonine was originally not going to be at major retailers – this is a direct-to-consumer product with free shipping that will keep the costs low for you: