Lemme GLP-1 Daily: Supresa-Based GLP-1 Support from Kourtney Kardashian

Kourtney Kardashian’s Lemme launches GLP-1 Daily, featuring clinically-studied Supresa saffron extract shown to reduce snacking by 55% in research. Not a GLP-1 drug, but a natural supplement designed to support appetite control.

The weight loss supplement industry has seen dramatic shifts over the past year, driven largely by the popularity of GLP-1 receptor agonist medications. Now, reality TV star and entrepreneur Kourtney Kardashian’s supplement brand Lemme is entering the conversation with Lemme GLP-1 Daily, a natural supplement designed to support the body’s own GLP-1 production and appetite control mechanisms.

Lemme GLP-1 Daily: A GLP-1 Supporting, and Appetite-Supressing Weight Loss Supplement

To be clear upfront – this is not a GLP-1 receptor agonist medication like Ozempic or Wegovy. Instead, Lemme GLP-1 Daily takes a different approach, using three clinically-studied ingredients that may help support the body’s natural hormone production and appetite signaling pathways.

The star of the show is Supresa, a novel saffron extract from PLT Health Solutions that’s been clinically shown to help reduce snacking frequency and support healthy appetite levels. But there’s also a lot to talk about in the other two ingredients, Eriomin and Morosil.

Kardashian states that she spent five years collaborating with doctors and scientists to develop her supplement line using clinically-backed ingredients. While celebrity-endorsed supplements often warrant skepticism, the formulation of Lemme GLP-1 Daily is actually both powerful and novel, combining the appetite-supporting effects of Supresa with two other ingredients that target different aspects of metabolic health.

Let’s examine how this formula works, with a particular focus on the clinical research behind its key ingredients — but first, check availability on PricePlow, and then we’ll get into the science:

Lemme GLP-1 Daily Ingredients

• Supresa® Saffron Extract (Crocus sativus (stigma)) – 176.5 mg (std. to 0.3% safranal)

  Supresa is a novel, patented^[1-4] saffron extract developed by PLT Health Solutions that’s engineered specifically for appetite control and weight management support.^[5] This unique ingredient stands out from generic saffron extracts thanks to its precise standardization and clinically-validated effects on satiety.

  A Background on Saffron

  The story of Supresa begins with Crocus sativus L., commonly known as saffron crocus. The crimson stigmas of this flower have been harvested by hand for over 3,500 years, requiring roughly 150 flowers to produce just one gram of saffron.^[6] These delicate threads contain unique compounds including safranal, crocin, and picrocrocin – natural molecules that research suggests can influence our relationship with food.^[7]

  A Special Form of Saffron – Targeting Appetite

  The development of Supresa marks an important shift in appetite management supplementation – moving away from stimulant-based approaches toward working with the body’s natural satiety mechanisms. Rather than forcing appetite suppression through artificial means, Supresa appears to help regulate the neurotransmitters involved in hunger and satisfaction.^[5]

  

  While saffron extracts have been studied for various health benefits, Supresa is specifically optimized and standardized for appetite control. The extract contains a precise ratio of active compounds that research suggests can help reduce snacking frequency and increase feelings of fullness when taken regularly.^[5]

  This science-based approach, combined with saffron’s long history of culinary and medicinal use, positions Supresa as a unique player in the growing market for natural appetite management solutions. Let’s take a closer look at the study on Supresa, which used the same 176.5mg dose we have here in Lemme GLP-1:

  The Science Behind Supresa

  The efficacy of Supresa was demonstrated in a groundbreaking randomized, double-blind, placebo-controlled study involving 60 healthy women with mild-to-moderate weight concerns.^[5]

  • Study Design: Clever Focus on “Snackers”

    What makes this clinical trial design so useful was its careful participant selection and monitoring methods. The researchers implemented a clever 2-week run-in period before randomization, which helped identify true “snackers” – people who regularly engaged in unplanned eating between meals. This pre-screening ensured they were studying the right population to evaluate Supresa’s effects on snacking behavior.

  • The Protocol

    

    Need help taming those snack attacks? Supresa is clinically validated saffron extract reduces snacking by 55% while working with your body’s natural satiety signals. No stimulants, just science backed satisfaction.

    The intervention itself was straightforward but precisely controlled. Women aged 25-45 with BMIs between 25-28 kg/m² were randomly assigned to one of two groups:^[5]

    • Supresa group: 176.5 mg of standardized saffron extract daily (split into two doses)
    • Placebo group: Identical-looking capsules with no active ingredients

    A key point that differentiates this study from many weight loss trials is that participants were not placed on any caloric restrictions. They were free to eat as they normally would, allowing researchers to isolate the effects of Supresa itself on natural eating patterns.

  • Remarkable Results

    The findings revealed several significant outcomes that demonstrate Supresa’s effectiveness:^[5]

    1. Snacking Reduction: The most dramatic result was a 55% decrease in snacking episodes in the Supresa group compared to just a 28% reduction in the placebo group.
    2. Appetite Control: By the end of the study, 100% of the women in the Supresa group reported decreased hunger sensations. Even more notably, about a quarter of these women described their appetite reduction as “significant.”
    3. Weight Management: While modest, the Supresa group showed statistically significant weight loss compared to placebo, losing 2.12 pounds over the 8-week period without any dietary restrictions.

  

  • Key Learnings

    This pivotal study revealed several important insights about Supresa:^[5]

    1. The extract works through appetite regulation rather than forced suppression – participants felt naturally more satisfied rather than artificially restricted.
    2. The effects appear cumulative, with benefits building over the 8-week period, suggesting Supresa works best as part of a consistent supplementation routine.
    3. Most importantly, it demonstrated that Supresa can help reduce snacking behavior without requiring strict dieting – a major advantage for real-world application.

    The study showed that Supresa offers a unique approach to weight management by targeting one of the most common obstacles to healthy eating: uncontrolled snacking. Rather than forcing changes through stimulants or blocking nutrient absorption, it appears to work by helping regulate the body’s natural satiety mechanisms.^[5]

  Kredit to Kourtney Kardashian on Choosing Supresa!

  We have to give credit where it’s due – while celebrity supplement brands often warrant skepticism, Kourtney Kardashian’s team clearly did their homework in selecting Supresa. Using the clinically-validated 176.5mg dose shows a commitment to evidence-based formulation rather than just marketing hype.

  

  To learn more about the fascinating science behind saffron for appetite control, including its mechanisms of action and complete safety data, check out our full article titled “Supresa: PLT Health’s Science-Backed Saffron Extract That Fights Food Cravings“.

  Better yet, Supresa is just one part of Lemme GLP-1 Daily’s innovative formula. Next, we’ll look at Eriomin, a specialized lemon extract that may help support the body’s natural GLP-1 production – the same hormone targeted by popular prescription weight loss medications. The combination of appetite control from Supresa with GLP-1 support from Eriomin creates an intriguing natural approach to weight management.

• Eriomin® Lemon Fruit Extract (Citrus limon) – 200 mg (std. to 70% eriocitrin)

  After Supresa’s appetite control benefits, Lemme GLP-1 takes an innovative turn by including Eriomin, a specialized lemon extract that supports the body’s natural GLP-1 production. This isn’t just any citrus extract – Eriomin is a patented nutraceutical standardized to contain 70% eriocitrin (eriodictyol-7-O-rutinoside), alongside beneficial compounds like hesperidin and naringin.^[8]

  

  While lemon flavonoids have long been studied for their antioxidant properties, Eriomin stands out by targeting multiple pathways involved in healthy glucose metabolism.^[8-10] Research has shown that it can boost GLP-1 levels by up to 22% – the same hormone targeted by popular prescription weight loss medications, but through natural means.^[9]

  The inclusion of this research-backed ingredient at its clinically-studied 200mg dose shows Lemme’s commitment to evidence-based formulation. When combined with Supresa’s appetite control benefits, this creates a multi-faceted approach to supporting healthy weight management through natural pathways.

  Let’s briefly dig into the research:

  Three Clinical Studies Supporting Eriomin’s Benefits

  The effectiveness of Eriomin has been validated through a series of groundbreaking clinical trials. Published in 2019, the first major human study demonstrated that Eriomin could help support healthy blood sugar levels and metabolic function – with 24% of participants showing significant improvements in glycemic markers over a 12-week period.^[10]

  • Blood Sugar and Metabolic Support

    Later research published in 2022 would show that 200mg of daily Eriomin supplementation increased GLP-1 levels by an average of 17.5% compared to placebo across multiple studies, with one trial showing increases as high as 22%.^[9]

    

    Lemme GLP-1 Daily is powered by a clnical dose of Supresa

    In this randomized, double-blind study, participants taking Eriomin showed significant improvements in several key markers on top of the 22% GLP-1 elevation:^[9]

    • 6% decrease in blood glucose levels
    • 11% reduction in insulin resistance markers
    • 13% decrease in glucagon levels
    • Improved inflammatory markers including IL-6 and TNF-α

    These results were achieved without any changes to diet or exercise routines.^[9]

  • Gut Health Connection

    A recent 2023 study revealed another fascinating aspect of Eriomin’s mechanism – its ability to positively influence gut bacteria associated with metabolic health. The research showed that Eriomin helped increase beneficial bacteria while reducing problematic strains linked to metabolic dysfunction.^[8]

  • Safety and Dosing

    Across multiple studies, Eriomin has demonstrated an excellent safety profile at the 200mg daily dose used in Lemme GLP-1 Daily. This consistent dosing strategy, backed by multiple clinical trials, provides confidence in both its effectiveness and safety profile.^[8-10]

    

    The research supports Eriomin as a multi-faceted ingredient that works through several complementary pathways – increasing GLP-1 production, supporting healthy blood sugar levels, and promoting beneficial gut bacteria. This makes it an ideal complement to Supresa in the Lemme GLP-1 formula, creating a comprehensive approach to metabolic support and weight management.

• Morosil™ Red Orange Fruit Extract (Citrus sinensis (L.) Osbeck) – 400 mg (std. to 0.8% anthocyanins)

  Rounding out Lemme GLP-1’s formula is Morosil, a standardized extract of Moro blood oranges that brings unique metabolic benefits to the table. This isn’t your average orange extract – Moro blood oranges are known for their deep red pigmentation, which comes from their rich anthocyanin content not found in standard citrus fruits.^[11]

  The clinical research behind Morosil is compelling. In a double-blind, placebo-controlled study, overweight participants taking 400mg of Morosil daily – the exact dose in Lemme GLP-1 Daily – showed significant reductions in body weight, BMI, and waist circumference over 12 weeks.^[12]

  Support through multiple pathways

  

  What makes Morosil so effective? Recent research has revealed it works through multiple pathways. The extract has demonstrated both anti-adipogenic (preventing fat cell formation) and antioxidant effects during the differentiation of fat cells.^[13]

  When fat cells were exposed to Morosil during development, researchers observed decreased triglyceride accumulation and reduced expression of key genes involved in fat storage. The extract also helped maintain healthy oxidative stress levels in these cells.^[13]

  While anthocyanins like cyanidin-3-glucoside play a major role in these benefits, research suggests it’s the synergistic effect of all compounds in Moro blood oranges – including hydroxycinnamic acids, flavanones, and vitamin C – that makes Morosil so effective.^[12]

  In Lemme GLP-1, Morosil complements both Supresa’s appetite control and Eriomin’s metabolic support by targeting fat cell development and oxidative balance. This multi-pathway approach helps explain why the formula shows promise for comprehensive weight management support.

Dosage and Directions

Users should take two capsules daily before meals for optimal effects. Lemme recommends consistent daily use for 3-6 months to experience the best results. For those taking blood sugar medications, always consult with your healthcare practitioner before beginning any new supplement regimen.

Conclusion: Safe Satiety Support from Lemme GLP-1

PLT Health Solutions: Growth Through Innovation

Lemme GLP-1 Daily represents a significant advancement in natural appetite management supplementation, particularly through its use of clinically-validated Supresa saffron extract at its studied 176.5mg dose. While celebrity supplement brands often warrant skepticism, Kourtney Kardashian’s team clearly did their homework in selecting three well-researched ingredients. The combination of appetite control from Supresa with two other metabolic support ingredients creates an intriguing natural approach to weight management support.