Black Magic Supply Dusk to Dawn: A Sleep Aid Like Never Before

When the Black Magic Supply team releases a product, they’re either going all in on high-intensity formulation strategies or bringing us something incredibly new from “beyond the ether” as it were originally prophesied in their momentous launch years ago.

We’ve been excited about the new Black Magic Villain pre-workout supplement, which brings a new high-energy twist compared to their famous BZRK formula, but there’s more to fitness life than just energy. There’s also sleep.

Black Magic Supply Dusk to Dawn

Black Magic Supply presents Dusk to Dawn, a wildly unique sleep aid featuring a new ingredient in Cocculus laurifolius and an older, repurposed one in theacrine! We discuss how it all works here.

Dusk to Dawn: A wildly unique sleep aid from Black Magic Supply

For today’s formula coverage, Black Magic Supply brings us Dusk to Dawn, a novel capsule-based sleep aid. Inside, we’re seeing a few novel takes: the appearance of a promising new ingredient in Cocculus laurifolius as well as a unique inclusion of theacrine, which isn’t commonly found in sleep aids… but perhaps should be!

Dusk to Dawn relies on both herbal ingredients (like Cocculus and valerian) as well as single-molecule compounds like 5-HTP and a small hit of melatonin (2 milligrams). Beyond that, we get a decent hit of magnesium glycinate, which we’ll basically never turn down before bed!

If you want to learn more, read on – but first, let’s check the PricePlow news and deals:

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Black Magic Supply Dusk to Dawn Ingredients

In a single, 3-capsule serving of Dusk to Dawn from Black Magic Supply, you get the following:

  • Cocculus Laurifolius (Cocculus Laurifolius DC) (leaf) – 1,034 mg

    Black Magic Supply Dusk to Dawn Sleep Aid Ingredients

    We’ve got some new stuff in here, and an ingredient in theacrine that’s often used in pre-workouts – this article explores it all!

    Cocculus laurifolius is a plant that’s been studied for its anticonvulsant and anxiolytic properties.[1,2]

    The basic mechanism of action behind Cocculus is its ability to act on the central nervous system’s GABAergic pathways.[1,2] This is a mechanism of action shared by many popular anti-anxiety supplements like theanine, magnesium, and glycine.

    Another way of putting it is that these supplements are anti-excitotoxic. Thanks to their upregulation of GABA, or downregulation of GABA’s antagonist glutamate, they help prevent excitotoxicity, which is the uncontrolled, sporadic neuronal firing that can produce neuroinflammation, seizures, and even permanent brain damage.[3,4] In its milder forms, excitotoxicity manifests as irritability, hyperactivity, or anxiety.[5-7]

    The GABAergic activity of Cocculus was shown in a study where researchers gave rats strychnine, which is a GABA antagonist and induces excitotoxic seizures that can be fatal. As it turns out, rats who got Cocculus showed significantly delayed seizure onset, longer survival times, and a higher survival rate than rats who got a placebo.[1] This implies that Cocculus is GABAergic enough to preserve GABA function in the face of strychnine exposure. The flavonoids in Cocculus appear to play a part in stabilizing neurons as well.[1]

    The anti-anxiety effects of Cocculus were shown in a mouse study in which researchers compared the behavior of Cocculus-treated mice with controls.[2] There was also a group that got diazepam, a powerful anti-anxiety drug that’s also sold under the name Valium.

    Anxiety was assessed by the light-dark box test and the open field paradigm. In these tests, mice who spend more time in the dark, or less time in the open, are thought to exhibit signs of anxiety.

    Cocculus Laurifolius Light-Dark Test

    Mice administered ethanolic extracts of Cocculus (ECL) showed significant reductions in anxious behavior, compared to the control group. The Cocculus mice spent more time in lighted or open areas than they did in dark or sheltered spaces.[2] Blue bars are the control group, red bars are for the diazepam group, green bars are for the 200 mg/kg ECL group, and black bars are for the 400 mg/kg ECL group.[2] D) percentage number of entries, E) percentage time spent and F) total number of rearing in light area in light-dark box test; G) number of center square crossings, (H) number of peripheral square crossings and I) total number of rearings in open-field paradigm.[2]

    Compared to the control mice, those who got diazepam exhibited far less avoidant and more exploratory behavior, spending more time in open and lighted areas than controls. That’s not terribly surprising. What is surprising is that the ECL extract did almost as well as the diazepam at improving certain behavior indicators.[2]

    For example, mice who got ECL spent almost as much time in lighted areas as mice who got diazepam (this is shown in figure E).[2] They also showed significantly more rearings (standing on their hind legs to survey the environment) in both lighted areas and open areas (figures F and I, respectively).[2]

    In addition, Cocculus laurifolius contains constituents that may function as muscle relaxants,[8] which is fitting for a sports nutrition brand like Black Magic Supply, whose customers are generally the type that train quite hard (as evidenced by their BZRK and Villain pre-workouts).

  • 5-HTP (5-hydroxytryptophan)(from Griffonia simplicifolia Extract) (Seed) – 250 mg

    Synthesis of the neurotransmitter serotonin requires 5-HTP as a precursor — and serotonin is a natural precursor to melatonin. Since serotonin and melatonin help regulate the circadian rhythm,[9] this makes 5-HTP a potentially useful supplement for improving sleep quality.

    Tryptophan to 5-HTP to Serotonin

    The Tryptophan to 5-HTP to Serotonin conversion. Image courtesy Wikimedia Commons

    At least one double-blind, randomized, placebo-controlled study has borne this out. Older adults who took 5-HTP for three months had about a 14% better global sleep score (GSS) by the end of the study period, compared to the placebo group.[9] The kicker is that this study only used a 100-milligram daily dose of 5-HTP – that’s less than half the amount in Dusk to Dawn!

    One study on 5-HTP supplementation in children suffering from chronic night terrors found that 93.5% of participants saw improvement in their condition.[10] The children were prescribed 2 mg/kg per day – that’s in the same ballpark as a 250-milligram dose for an adult.

    Black Magic Supply Dusk to Dawn Teaser

    Tomorrow — and the most unique sleep aid we’ve seen in years — has come!

    We often see 50-100 milligram doses of 5-HTP in sleep aids, so this is impressive. We often consider it a nice way of creating a “time-released” serotonin and melatonin, since it can help promote their synthesis downstream.

  • Valerian Root Extract (Valeriana officinalis) (.08% valerenic acids) – 175 mg

    Valerian root, known officially as Valeriana officinalis, is an herb that grows in Europe, Asia, and North America. It’s used to manage symptoms of anxiety and insomnia.[11] The root of valerian is rich in antioxidants, particularly valerenic acid and isovaleric acid, its primary bioactive constituents.[11] Both compounds have been found to upregulate GABA, leading to feelings of increased relaxation and decreased feelings of perceived stress and anxiety.[11]

    Valerian doesn’t necessarily help you fall asleep faster – research on its ability to improve time to onset of sleep is a mixed bag[12-15] – but it does seem to significantly improve sleep quality.[12,15]

  • Theacrine – 16.6 mg

    Theacrine as a sedative is an interesting subject in the supplement industry. There’s been a fair amount of controversy over whether theacrine is stimulating or sedative, but, as it turns out, the answer is… both. It’s stimulating in high doses, and sedating in low doses![16]

    Black Magic Dusk to Dawn Benefits

    Animal research indicates that theacrine, when co-administered with the depressant phenobarbital, can increase the duration of sleep induced by phenobarbital. Caffeine, the famous stimulant, has the opposite effect when given with phenobarbital![17]

    This makes theacrine a very interesting play in a sleep aid. Some users anecdotally feel very sleepy when using it – even in pre-workout supplements next to caffeine – so to them, it makes sense here. But for those who like its effects next to stimulants, a low-dose like this in a sleep aid may just surprise them.

    We’d love to specify the mechanism of action here, but nobody knows yet! It remains to be elucidated by science.[16] Theacrine is known to help optimize 5-HTP production, though, so regulating circadian function through serotonin probably has something to do with it.

    Overall, we have been waiting quite a while for someone to give this a shot – and we’re happy Black Magic Supply did it with Dusk to Dawn. They definitely didn’t put a boring product together here!

  • Melatonin – 2 mg

    The hormone melatonin plays a central role in governing the body’s circadian rhythm. Its secretion is a signal that it’s time to sleep,[18] and repeated melatonin exposures, at a particular time of day, can be used to set your body’s natural bedtime, which is why the hormone is often used to manage jet lag.[19]

    Melatonin’s interaction with blue light

    Black Magic Supply Dusk to Dawn Label Side / Dosage

    Melatonin sets your body’s internal clock for waking and sleeping[18] by interacting with light in your environment. This happens because arylalkylamine N-acetyltransferase, the enzyme responsible for producing melatonin, is downregulated when light hits your eyes. In nature, this happens while the sun is up.[20] Morning light helps wake us up partly by suppressing melatonin production.[21]

    The color (or, more technically, wavelength) of light that’s primarily responsible for suppressing melatonin is blue light.[22] This should make intuitive sense, as blue skies are what we usually see in the middle of the day.

    The tricky, and unfortunate, thing is that not only natural light does this. Blue light from technological sources like TV screens, computer monitors, and, most troublingly, cell phones can also downregulate the enzyme.[23]

    Fortunately, when taken at the right time before bed, melatonin supplements can help correct this problem. Melatonin has been shown to significantly increase sleep quality without significant adverse effects, particularly in older adults.[24]

    Other studies have found that melatonin supplementation can help mitigate sleep disturbances like migraines and insomnia.[25,26]

    Because it has persistent effects on the circadian clock, it’s important to only take melatonin at your intended regular bedtime, and combine it with good sleep hygiene practices like avoiding blue light exposure in the evening.[27]

  • Magnesium (as Magnesium Glycinate) – 75 mg (18% DV)

    Magnesium is an essential mineral with many metabolic benefits. Restoring magnesium levels, even in cases of mild or subclinical deficiency, can have significant positive effects on crucial aspects of health, like blood sugar, insulin production, and insulin sensitivity.[28-34]

    Black Magic Supply Dusk to Dawn

    Again, even mild deficiencies in magnesium can lead to or worsen stress and anxiety,[35-37] which obviously isn’t great for sleep quality. One study in seniors found improvements in sleep EEGs (brain wave recordings) from magnesium supplementation.[38]

    Why magnesium glycinate?

    Magnesium glycinate, which is a magnesium molecule bound to the amino acid glycine, is our favorite form of magnesium thanks to its very high bioavailability, and the fact that we love glycine. It’s far more bioavailable than cheaper, more common forms like magnesium oxide.[39]

    As glycine is GABAergic,[40] supplementing with glycine itself can also reduce stress and decrease time to sleep onset. However, the doses used are typically much larger than what’s in Dusk to Dawn, usually on the order of at least 3 grams per day.[41-51]

    Still though, we have some glycine, so it should help a bit.

    The prevalence of magnesium deficiency

    Black Magic Supply VILLAIN Announced

    Are you ready for the new Black Magic Supply VILLAIN pre-workout

    Because magnesium is involved in so many different processes, magnesium deficiency is tough to diagnose, but usually takes the form of fatigue, insulin resistance, and suboptimal cardiovascular function.[52,53]

    It seems like many (if not most) of us are dealing with these symptoms today. So how common is magnesium deficiency?

    The first thing to know is that Americans used to get a lot more magnesium from our food than we do today. This is because the magnesium content of soil and,hence, the food we produce on our soil, has declined precipitously in the last 100 years.[52,54-58]

    Another challenge is that the diagnostic threshold for magnesium deficiency may not be adequate – 0.75 mmol/L serum magnesium is considered sufficient, but some research shows that levels below 0.863 mmol/L increase risk of diabetes by more than 300%.[59] This means there are probably lots of undiagnosed magnesium deficiency cases out there.

    One study points out that magnesium deficiency prevalence is probably getting worse. As of 2006, only 48% of the U.S. population was consuming the recommended amount of magnesium, down from 56% in 2002.[60]

    Long story short: this is a solid boost of magnesium and glycine… but check your diet — you may actually want more!

Dosage and Timing

Take 1-3 capsules 30 minutes before bed. Since Dusk to Dawn contains a new ingredient in Cocculus, it’s not a bad idea to start light. Additionally, melatonin tolerances vary, so that could help drive the dosage here – if 2 milligrams of melatonin is too much, 1-2 capsules could support a more refreshed wakeup.

Dusk to Dawn: A new and unique sleep aid

This is an extraordinarily interesting formula, with more departures from the norm than usual. Cocculus is an ingredient we’ve never covered in a sleep formula before – the research is promising (yet we definitely want more), so we’re excited to hear feedback from consumers and industry professionals on this formula’s effectiveness.

Black Magic Supply Dusk to Dawn Benefits

Using low-dose theacrine is a very savvy move we’ve long been waiting for someone to take a stab at. Partisans have spilled a lot of ink denying that theacrine has sedative effects despite compelling evidence that it does, so it’s ironic and refreshing to see the low-dose application being embraced here.

The dose of 5-HTP is also awesome – way beyond the 50-100 milligrams typically used. Valerian also has a well-researched track record — you can definitely use a couple extra botanicals when using capsules.

Finally, magnesium is a great ingredient for this application, too, and it’s especially nice that Black Magic has opted for one of the best (if not the best) forms of this mineral, which is magnesium glycinate. We normally recommend higher doses, but this is a capsule-based product and quality forms of magnesium take up a lot of space. So if you need more magnesium, and you very well may, you can always add more separately.

With that said, this is a phenomenally unique product and we’re excited to give it a whirl.

Black Magic Dusk To Dawn – Deals and Price Drop Alerts

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Posts are sponsored in part by the retailers and/or brands listed on this page.

About the Author: Mike Roberto

Mike Roberto

Mike Roberto is a research scientist and water sports athlete who founded PricePlow. He is an n=1 diet experimenter with extensive experience in supplementation and dietary modification, whose personal expertise stems from several experiments done on himself while sharing lab tests.

Mike's goal is to bridge the gap between nutritional research scientists and non-academics who seek to better their health in a system that has catastrophically failed the public. Mike is currently experimenting with a low Vitamin A diet.

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  1. Maqbool, Sidra et al. “Neuro-pharmacological evaluation of anticonvulsant and neuroprotective activity of Cocculus laurifolius leaves in wistar rats.” Metabolic brain disease vol. 34,4 (2019): 991-999. doi:10.1007/s11011-019-00414-3;
  2. Maqbool, Sidra, and Ishrat Younus. “Anxiolytic and Hypnotic Effects of Cocculus Laurifolius Leaf Extract in Mice.” Bangladesh Journal of Pharmacology, vol. 14, no. 1, 21 Feb. 2019, pp. 45–53, doi:10.3329/bjp.v14i1.38093;
  3. Johanssen, Timothy et al. “PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning.” Neurobiology of disease vol. 81 (2015): 176-85. doi:10.1016/j.nbd.2015.02.008;
  4. Olloquequi, Jordi et al. “Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications.” Journal of psychopharmacology (Oxford, England) vol. 32,3 (2018): 265-275. doi:10.1177/0269881118754680;
  5. Dos Santos, Tiago Marcon et al. “Mild Hyperhomocysteinemia Causes Anxiety-like Behavior and Brain Hyperactivity in Rodents: Are ATPase and Excitotoxicity by NMDA Receptor Overstimulation Involved in this Effect?.” Cellular and molecular neurobiology vol. 42,8 (2022): 2697-2714. doi:10.1007/s10571-021-01132-0
  6. Nasir, Madeeha et al. “Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA Psychopharmacology.” Frontiers in psychiatry vol. 11 548505. 19 Nov. 2020, doi:10.3389/fpsyt.2020.548505;
  7. Onaolapo, Adejoke Yetunde, and Olakunle James Onaolapo. “Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule.” World journal of psychiatry vol. 11,7 297-315. 19 Jul. 2021, doi:10.5498/wjp.v11.i7.297;
  8. Mukherjee, K. C., et al. “Mechanism of Neuromuscular Blocking Action of Isocorydine Methochloride, a New Quaternary Alkaloid from Cocculus Laurifolius DC.” Indian Journal of Experimental Biology, vol. 22, no. 1, 1 Jan. 1984, pp. 54–56;
  9. Sutanto, Clarinda et al. “The Impact of 5-Hydroxytryptophan Supplementation on Sleep Quality of Older Adults in Singapore: A Randomized Controlled Trial.” Current Developments in Nutrition vol. 5,Suppl 2 372. 7 Jun. 2021, doi:10.1093/cdn/nzab037_082;
  10. Bruni, Oliviero et al. “L -5-Hydroxytryptophan treatment of sleep terrors in children.” European journal of pediatrics vol. 163,7 (2004): 402-7. doi:10.1007/s00431-004-1444-7
  11. Benke D. et al; “GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts”; Neuropharmacology. 2009 Jan;56(1):174-81;
  12. Barton, Debra L. et al. “The Use of Valeriana Officinalis (Valerian) in Improving Sleep in Patients Who Are Undergoing Treatment for Cancer: A Phase III Randomized, Placebo-Controlled, Double-Blind Study: NCCTG Trial, N01C5.”; The journal of supportive oncology 9.1 (2011): 24–31;
  13. Leathwood, P; “Aqueous Extract of Valerian Reduces Latency to Fall Asleep in Man;” Planta Med 1985; 51(2): 144-148;
  14. Fernandez-San-Martin, M; “Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials;” Sleep Med. 2010 Jun;11(6):505-11;
  15. Taavoni, S; “Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial.”; Menopause. 2011 Sep;18(9):951-5;
  16. Sheng, Yue-Yue et al. “Theacrine From Camellia kucha and Its Health Beneficial Effects.” Frontiers in nutrition vol. 7 596823. 17 Dec. 2020, doi:10.3389/fnut.2020.596823;
  17. Xu, Jie-Kun et al. “Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice.” Journal of Asian natural products research vol. 9,6-8 (2007): 665-72. doi:10.1080/10286020601103155
  18. Tordjman, Sylvie et al. “Melatonin: Pharmacology, Functions and Therapeutic Benefits.” Current neuropharmacology vol. 15,3 (2017): 434-443. doi:10.2174/1570159X14666161228122115
  19. Herxheimer, A, and K J Petrie. “Melatonin for the prevention and treatment of jet lag.” The Cochrane database of systematic reviews ,2 (2002): CD001520. doi:10.1002/14651858.CD001520
  20. Hardeland, R. “Melatonin, hormone of darkness and more: occurrence, control mechanisms, actions and bioactive metabolites.” Cellular and molecular life sciences : CMLS vol. 65,13 (2008): 2001-18. doi:10.1007/s00018-008-8001-x.
  21. Gooley, Joshua J et al. “Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans.” The Journal of clinical endocrinology and metabolism vol. 96,3 (2011): E463-72. doi:10.1210/jc.2010-2098.
  22. Tähkämö, Leena et al. “Systematic review of light exposure impact on human circadian rhythm.” Chronobiology international vol. 36,2 (2019): 151-170. doi:10.1080/07420528.2018.1527773
  23. Tähkämö, Leena et al. “Systematic review of light exposure impact on human circadian rhythm.” Chronobiology international vol. 36,2 (2019): 151-170. doi:10.1080/07420528.2018.1527773.
  24. Lemoine, Patrick, et al. “Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects.” Journal of Sleep Research vol 16,4 (2007): 372-80. doi:10.111/j.1365-2869.2007.00613.x
  25. Alstadhaug, K. B., et al. “Prophylaxis of Migraine with Melatonin: A Randomized Controlled Trial.” Neurology, vol. 75, no. 17, 25 Oct. 2010, pp. 1527–1532, 10.1212/wnl.0b013e3181f9618c;
  26. Luthringer, Remy, et al. “The Effect of Prolonged-Release Melatonin on Sleep Measures and Psychomotor Performance in Elderly Patients with Insomnia.” International Clinical Psychopharmacology, vol. 24, no. 5, Sept. 2009, pp. 239–249, 10.1097/yic.0b013e32832e9b08;
  27. van Geijlswijk, Ingeborg M et al. “Evaluation of sleep, puberty and mental health in children with long-term melatonin treatment for chronic idiopathic childhood sleep onset insomnia.” Psychopharmacology vol. 216,1 (2011): 111-20. doi:10.1007/s00213-011-2202-y;
  28. Guerrero-Romero, Fernando, and Martha Rodríguez-Morán. “Magnesium Improves the Beta-Cell Function to Compensate Variation of Insulin Sensitivity: Double-Blind, Randomized Clinical Trial.” European Journal of Clinical Investigation, vol. 41, no. 4, 17 Jan. 2011, pp. 405–410, 10.1111/j.1365-2362.2010.02422.x;
  29. Hatzistavri, L. S., et al. “Oral Magnesium Supplementation Reduces Ambulatory Blood Pressure in Patients with Mild Hypertension.” American Journal of Hypertension, vol. 22, no. 10, 1 Oct. 2009, pp. 1070–1075, 10.1038/ajh.2009.126;
  30. Kawano, Yuhei, et al. “Effects of Magnesium Supplementation in Hypertensive Patients.” Hypertension, vol. 32, no. 2, Aug. 1998, pp. 260–265, 10.1161/01.hyp.32.2.260;
  31. Guerrero-Romero, F, and M Rodríguez-Morán. “The Effect of Lowering Blood Pressure by Magnesium Supplementation in Diabetic Hypertensive Adults with Low Serum Magnesium Levels: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.” Journal of Human Hypertension, vol. 23, no. 4, 20 Nov. 2008, pp. 245–251, 10.1038/jhh.2008.129;
  32. Rodriguez-Moran, M., and F. Guerrero-Romero. “Oral Magnesium Supplementation Improves Insulin Sensitivity and Metabolic Control in Type 2 Diabetic Subjects: A Randomized Double-Blind Controlled Trial.” Diabetes Care, vol. 26, no. 4, 1 Apr. 2003, pp. 1147–1152, 10.2337/diacare.26.4.1147;
  33. Mooren, F. C., et al. “Oral Magnesium Supplementation Reduces Insulin Resistance in Non-Diabetic Subjects – a Double-Blind, Placebo-Controlled, Randomized Trial.” Diabetes, Obesity and Metabolism, vol. 13, no. 3, 24 Jan. 2011, pp. 281–284, 10.1111/j.1463-1326.2010.01332.x;
  34. Golf, S.W., et al. Cardiovascular Drugs and Therapy, vol. 12, no. 2suppl, 1998, pp. 197–202, 10.1023/a:1007708918683;
  35. Cuciureanu MD, Vink R; “Magnesium and stress”; Magnesium in the Central Nervous System;
  36. Ebrahimi, Elham, et al. “Effects of Magnesium and Vitamin B6 on the Severity of Premenstrual Syndrome Symptoms.” Journal of Caring Sciences, vol. 2012, no. 4, pp. 183–189, 10.5681/jcs.2012.026;
  37. L, Barragán-Rodríguez, et al. “Efficacy and Safety of Oral Magnesium Supplementation in the Treatment of Depression in the Elderly with Type 2 Diabetes: A Randomized, Equivalent Trial.” Magnesium Research, 1 Dec. 2008;
  38. Held, Katja, et al. “Oral Mg(2+) Supplementation Reverses Age-Related Neuroendocrine and Sleep EEG Changes in Humans.” Pharmacopsychiatry, vol. 35, no. 4, 1 July 2002, pp. 135–143, 10.1055/s-2002-33195;
  39. Schuette, S A et al. “Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection.” JPEN. Journal of parenteral and enteral nutrition vol. 18,5 (1994): 430-5. doi:10.1177/0148607194018005430
  40. Bowery, N G, and T G Smart. “GABA and glycine as neurotransmitters: a brief history.” British journal of pharmacology vol. 147 Suppl 1,Suppl 1 (2006): S109-19. doi:10.1038/sj.bjp.0706443
  41. Inagawa, K; Subjective effects of glycine ingestion before bedtime on sleep quality; Sleep and Biological Rhythms, 4: 75–77; 2006;
  42. Yamadera, Wataru, et al. “Glycine Ingestion Improves Subjective Sleep Quality in Human Volunteers, Correlating with Polysomnographic Changes.” Sleep and Biological Rhythms, vol. 5, no. 2, 27 Mar. 2007, pp. 126–131, 10.1111/j.1479-8425.2007.00262.x.
  43. Bannai, Makoto, et al. “The Effects of Glycine on Subjective Daytime Performance in Partially Sleep-Restricted Healthy Volunteers.” Frontiers in Neurology, vol. 3, 2012, 10.3389/fneur.2012.00061;
  44. Berger, Albert J. “What Causes Muscle Atonia in REM?” Sleep, vol. 31, no. 11, 2008, pp. 1477–8;
  45. Chase, MH, et al. “Evidence That Glycine Mediates the Postsynaptic Potentials That Inhibit Lumbar Motoneurons during the Atonia of Active Sleep.” The Journal of Neuroscience, vol. 9, no. 3, 1 Mar. 1989, pp. 743–751, 10.1523/JNEUROSCI.09-03-00743.1989;
  46. Brooks, Patricia L., and John H. Peever. “Unraveling the Mechanisms of REM Sleep Atonia.” Sleep, vol. 31, no. 11, 1 Nov. 2008, pp. 1492–1497;
  47. Brooks, P. L., and J. H. Peever. “Identification of the Transmitter and Receptor Mechanisms Responsible for REM Sleep Paralysis.” Journal of Neuroscience, vol. 32, no. 29, 18 July 2012, pp. 9785–9795, 10.1523/jneurosci.0482-12.2012;
  48. Cummings, Kirstie A., and Gabriela K. Popescu. “Glycine-Dependent Activation of NMDA Receptors.” The Journal of General Physiology, vol. 145, no. 6, 11 May 2015, pp. 513–527, 10.1085/jgp.201411302.
  49. Kawai, Nobuhiro, et al. “The Sleep-Promoting and Hypothermic Effects of Glycine Are Mediated by NMDA Receptors in the Suprachiasmatic Nucleus.” Neuropsychopharmacology, vol. 40, no. 6, 1 May 2015, pp. 1405–1416, 10.1038/npp.2014.326;
  50. Inagawa, K; Subjective effects of glycine ingestion before bedtime on sleep quality; Sleep and Biological Rhythms, 4: 75–77; 2006;
  51. Yamadera, Wataru, et al. “Glycine Ingestion Improves Subjective Sleep Quality in Human Volunteers, Correlating with Polysomnographic Changes.” Sleep and Biological Rhythms, vol. 5, no. 2, 27 Mar. 2007, pp. 126–131, 10.1111/j.1479-8425.2007.00262.x.
  52. Workinger, Jayme, et al. “Challenges in the Diagnosis of Magnesium Status.” Nutrients, vol. 10, no. 9, 1 Sept. 2018, p. 1202, 10.3390/nu10091202;
  53. DiNicolantonio, James J, et al. “Subclinical Magnesium Deficiency: A Principal Driver of Cardiovascular Disease and a Public Health Crisis.” Open Heart, vol. 5, no. 1, Jan. 2018, p. e000668, 10.1136/openhrt-2017-000668;
  54. USDA, Agricultural Research Service USDA National Nutrient Database for Standard Reference, Release 28;
  55. Beeson K.C. The Mineral Composition of Crops with Particular Reference to the Soils in Which They Were Grown: A Review and Compilation. U.S. Department of Agriculture; Washington, DC, USA: 1941;
  56. Firman B. Ash and Mineral Cation Content of Vegetables. Soil Sci. Soc. Am. Proc. 1948;13:380–384;
  57. Lindlahr H. Nature Cure. Volume I The Nature Cure Publishing Co.; Chicago, IL, USA: 1914. (Philosophy and Practice Based on the Unity of Disease and Cure; The Nature Cure Series);
  58. USDA, Agricultural Research Service USDA National Nutrient Database for Standard Reference, Release 13;
  59. Wang, Jui-Line et al. “Magnesium status and association with diabetes in the Taiwanese elderly.” Asia Pacific journal of clinical nutrition vol. 14,3 (2005): 263-9.
  60. Rosanoff, Andrea et al. “Suboptimal magnesium status in the United States: are the health consequences underestimated?.” Nutrition reviews vol. 70,3 (2012): 153-64. doi:10.1111/j.1753-4887.2011.00465.x

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