Anatabloc Slammed by Jon Stewart – Here’s the REAL Truth

Recently, an episode of The Daily Show With Jon Stewart made fun of a new supplement called Anatabloc.

In this article, you will learn the real truth behind Anatabloc, including what it is and whether or not it’s worth your time and money.


The supplement industry is full of bizarre products. Some of them have turned out to be incredible, while others get swept under the rug and forgotten about due to their lackluster results.

Recently, one of these strange supplements has come into the limelight as the butt end of more than one joke, from none other than Comedy Central’s own Jon Stewart[1].

Jon Stewart - Anatabloc

Jon Stewart makes it hard to take Anatabloc serious. Is it even worth taking serious though?

Click image to play the clip

The strange supplement he was poking fun at was Anatabloc.

If you’ve had a chance to hear him talk about Anatabloc, it might be hard for you to take the supplement serious.

All jokes aside though, this article is going to take an in depth look into the supplement.

I’m going to discuss the science behind it, and whether or not it’s worth your hard earned cash.

What is Anatabloc?

Anatabloc is an anti-inflammatory supplement. Its main component and active ingredient is anatabine.

What makes it so strange, is that anatabine is an alkaloid derived from tobacco. It’s not every day that you come across a health supplement based off of tobacco.

Initially, the company made many wild claims about Anatabloc.

However, the product description has been toned down a notch, now only claiming to help prevent and reduce inflammation.

Does it actually work?

Does Anatabloc Work?

Does it even work? Short answer: No… at least not at these dosages.

The short answer: No… at least, not at the dosages we’re seeing.

That’s not to say that anatabine doesn’t help with inflammation. It still needs to be researched further, however it does appear to work to some degree.[2,3]

Dosage is the problem

That problem is, the dose in Anatabloc isn’t sufficient enough to bring about any benefits.

The lowest effective dose for humans is somewhere between 70 – 100 mgs for a 150 lb adult. You would need to consume about 50 servings of Anatabloc to reach the required amount, which could potentially open the door to all sorts of side effects.

Obviously, it’s been severely under-dosed as is, and effects will be negligible according to current research.

Where can I find Anatabloc?

Here’s what’s even funnier – when this video aired, it was in stock at GNC for a cool $99.99. Now, it’s nowhere to be found there!

Did Jon Stewart’s humor actually grab the attention of GNC’s heads and get this product removed from the shelves?

Either way, that is the only PricePlow-based store where it was available, and it no longer is. If you want, you can go to our official Anatabloc page and sign up for product updates, but


Perhaps in the future anatabine will have more research in it’s favor. For now though, the research is limited.

The only evidence that does support it, suggests that much higher doses are needed than what’s available in Anatabloc.

The bottom line: Anatabloc Product

When it comes to anti-inflammatory supplements, you can do much better than Anatabloc.

There are plenty of anti-inflammation products on the market that are more affordable, with more research backing them.

You can find some of them here, on our joint supplements page.

For now though, we suggest that you stay away from Anatabloc.


  1. Comedy Central; “The Daily Show With Jon Stewart 8-7-14;” August 2014

  2. Jenkins N., et al.; Journal of the International Society of Sports Nutrition; “The effects of anatabine on non-invasive indicators of muscle damage: a randomized, double-blind, placebo-controlled, crossover study;” July 2013

  3. Paris D., et al.; European journal of pharmacology; “Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation;” November 2012

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  • PECB

    P { margin-bottom: 0.08in; }

    effective product/substance/discovery
    (anatabine citrate — which can be extracted from tobacco, peppers,
    tomatoes, eggplant and any other member of the nightshade family)
    that has proven helpful, if not downright completely effective in the
    treatment of pain and the amelioration of underlying health issues
    that are caused by, or have chronic inflamation as a cofactor (be it
    joint pain, arthritis, alzhimers, multiple sclerosis, etc…).

    [note: it may not “cure” ,
    but at this point all clinical research, as well as many reports from
    product users indicates that in a majority of cases it sure does

    In my case I suffered from debilitating
    joint pain in my feet, ankles, and knees (reason unknown despite
    seeing several doctors and undergoing a variety of tests) which made
    it difficult and extremely painful to walk. Nothing helped much,
    until I tried anatabloc. I am now completely pain free 99% of the
    time — anatabloc essentially gave me my life back.

    As of this writing, Rock Creek
    Pharmaceuticals has been forced to pull anatabloc from the market due
    to a disingenuous FDA that doesn’t follow its own rules/guidelines
    (anatabine based products were originally released under a certain
    set of rules/guidlines that the FDA has decided to ignore — wonder
    whose profits/power anatabine based products threaten). Hopefully
    Rock Creek Pharmaceuticals can figure out how to pacify the
    government thugs &/or who is pulling their strings and bring the
    product back to market soon. In the meantime, I’m buying up all I can
    and hopefully it’ll tide me over till it comes back to market.

    If by chance it’s kept suppressed, I’ll
    even go so far as to setup my own chem lab (I have the background to
    figure it out) to make the stuff — it’s that effective and

    • Lynn

      If you are making it for yourself , could you please share your expertise with me so that I can continue giving it to my son with autism for whom it is highly effective too.
      all the best

  • Kulabacsi

    Did it work for me ? The short answer is: yes. Even at the low doses the product was completely eliminating my chronic prostatitis symptoms. I don’t think it is a miracle drug, but the average feedback on Amazon/GNC was good, the facebook page had many success stories. Obviously with a publicly traded company there is always the short interest. It was a particularly bad management move to involve politics with the product/company (McDonnell scandal).
    AFAIC, the FDA did the same thing with anatabine-citrate as they did with red yeast rice. After lovastatin was synthetized by Merck, the FDA forced the red yeast rice producers to remove the naturally occuring statins from the nutraceutical. Guess who made a killing by patenting the synthesized variations of the naturally occurring statins ? In 2005, statin based drug variations brought an estimated $18.7 billion to big pharma. I understand GMP, validation and all, but I don’t understand why can’t people decide whether to buy cheap, red yeast rice with uncontrolled ANI (active nutraceutical ingredient) vs patented statins with controlled API.
    The interesting link between anatabine and the statins: by now quite a few doctors believe that low grade inflammation of the artery walls is a bigger issue than elevated LDL cholesterol levels. Without inflammation, cholesterol wouldn’t deposit on the artery walls. I guess, with gaining popularity, someone started to worry about Anatabine citrate. Was it a mistake to compare the anti-inflammatory effect of Anatabine to lipitor ?
    Also, if you are type 1 or insulin dependent type 2 diabetic, you may want to ask a question from your doctor or government representative: how is it possible that they discovered insulin 90 years ago, still there is no low cost generic version available in the USA ?

  • RogerDane

    It helped greatly with inflammation issues for me. I cannot even begin to explain the relapse that I experienced when this went off the market. Terrible pain. People like Stewart have no understanding. I used a little over five tabs daily and the quality of life was so improved. I wish the worst to people (the short sellers and folks like Stewart) who could not see far enough ahead.

  • JDKeg

    John Stewart is bought and paid for. He is a talking head for the establishment, a politically correct guy that has no balls left of his own.
    I used this product for two years and it was fantastic. Anatabloc has a short half-life as dosages are weight appropriate. I needed the largest dosage, two small lozenges (that are like a tick-tack), 6 times a day because I’m a bigger guy. But I could always sense when it was wearing off and if I didn’t take another dosage, I would be in pain soon after that. I had an Auto-Immune disease and this product gave me much of my life back. Shame on John Steward for being a Nazi.

    The active ingredient Anatibine is found in tobacco but is also in many, many plants, tomatoes and red peppers and so on. The FDA had first decided since Anatibine was a natural compound the product Anatabloc didn’t need FDA clearance but after the product worked so well the FDA decided to reign it in and make the company, Rock Creek Pharmaceuticals a division of Star Scientific go through the regular clearance tests with the FDA. Essentially it seems the government wanted it’s billions and could get it. So the company, Star Scientific had to stop sales of Anatabloc and start with the tests, which it is doing now. I’m pretty sure this will be a blockbuster once it’s FDA cleared. And Star Scientific will have pharmaceutical status and the product itself will become much more expensive than $100.00 for a months supply because it does work. And to John Stewart > You are an idiot!

  • morning_in_america

    My wife has a thyroid condition and it worked wonders for her. Clearer mind, also reduced arthritis pain. I used it to reduce inflammation from gout. virtually no side effects. Too bad the dirty democrats got it banned…I guess they got a big check from the pharmaceutical cos.

  • Debbie Focht

    I think neither Jon Stewart nor the author of this article know what they’re talking about. According to Izabella Wentz, pharmacist and author of “Root Cause,” anatabine has been shown to reduce antibodies in people suffering from Hashimoto’s autoimmune thyroid disease at dosages of 5 mg – 12 mg per day for a 100-pound woman. Now because of the paid shillings, I can’t find it anywhere? Thanks. It’s great to know there are folks out there who have the backs of people suffering from autoimmune disease.