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Dr. Sergej M. Ostojic

Guanidinoacetic Acid (GAA): A Guide to Creatine's Precursor - Benefits, Risks, and Strategies with CreGAAtine

Guanidinoacetic Acid (GAA): A Guide to Creatine’s Precursor – Benefits, Risks, and Strategies with CreGAAtine

Guanidinoacetic acid (GAA) is creatine's immediate precursor that may enhance muscle creatine levels more effectively than creatine alone, but carries potential risks including elevated homocysteine and theoretical neurotoxicity concerns when used alone. These risks are largely mitigated by proper formulation and dosing, such as with CreGAAtine, which uses B-vitamin co-factors to mitigate homocysteine elevation.

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