The amount of times we’ve discussed New Zealand on the blog can probably be counted on one hand. Dubbed “Paradise of the Pacific”, most probably know of the country for its breathtaking and picturesque landscapes which served as the filming locations for the famed Lord of the Rings motion picture trilogy.
As it turns out, there’s much more than a collection of pretty landscapes and sightseeing in NZ. They also happen to have a solid dietary supplement industry down there, much of it stemming from the top-notch protein that comes from their prized cows. Today’s blog highlights a little known company, Pumped Sports, that’s doing big things down there.
Pumped Sports Loaded is a comprehensive pre workout that’ll check all the boxes you’re looking for in a top of the line pre workout.
See the massive label below:
It doesn’t matter if you’re looking for energy, focus, pumps, or endurance. Loaded delivers on all fronts.
Hang on boys and girls because we’ve got a lot of ground to cover!
CarnoSyn® Beta Alanine (2.5g)
Loaded gets things rolling with the ingredient most well known for its endurance boosting capabilities: Beta Alanine. CarnoSyn® is the highest quality form of BA at that.
When ingested, BA hooks up with another amino acid, histidine, to form carnosine in the body. This new molecule acts as a powerful intracellular buffer that helps remove lactic acid buildup in the muscle. Less lactic acid leads to all sorts of benefits including: improved endurance, greater power and strength, and reduced fatigue.[2,3,4]
Betaine Anhydrous (1.25g)
Betaine is a metabolite of choline as well as a component of beetroot. It is a strong player in methylation in the body as well as an osmoregulator of creatine. What’s this got to do with workout performance?
Well, betaine supplementation has found to increase power, reduce soreness, boost muscle protein synthesis, and enhance the body’s production of creatine![5,6,7,8]
The clinical dose recommended to fully see these benefits is 2.5g, but this gets us halfway there.
Agmapure™ Agmatine Sulfate (1g)
We’re huge fans of agmatine in pre workouts for its ability to “prolong” pumps. This neurotransmitter/neuromodulator prevents the breakdown of L-Arginine by inhibiting the enzyme Arginase. L-Arginine is the amino acid responsible for nitric oxide production in the body.
Basically, you want arginine active as long as possible because it translates to greater N.O. production resulting in significantly more vasodilation and blood flow. The end result are some killer pumps!
Most pre workouts only contain around 500mg, but not here, Loaded packs in a solid 1g dose that’ll will make for some very fun and “painful” pumps.
Taurine is a conditionally essential amino acid predominantly located in the brain, heart, and skeletal muscle of the body. However during intense workouts, it gets depleted rather quickly and needs to be replenished quickly.
The real benefit to taurine is its ability to act as a cell volumizer, helping to draw water into the muscle belly. This enhances “water based pumps” as well as endurance. Additionally, taurine may also reduce symptoms of delayed onset muscle soreness (DOMS) as well as boost focus.
Nitrosigine® can be thought of as a “revamped” version of the old pump booster Arginine. This newer form, developed by Nutrition21, comes by way of combining arginine with inositol and potassium silicate. The bioavailability of arginine and silicate is vastly improved by this new patented form.
Nitrosigine’s will increase N.O. production in the body, leading to increased vascularity and most important of all…PUMPS!!
N-Acetyl L-Tyrosine (500mg)
L-Tyrosine is another favorite focus booster in pre workouts. N-Acetyl L-Tyrosine (NALT) is the acetylated form of the amino acid that offers improved bioavailability over the standard “L-” form.
Tyrosine enhances focus by increasing the production of two key neurotransmitters in the body, noradrenaline and dopamine in the body. This duo supports healthy mood and reduces symptoms of stress and anxiety,[15,16] aside from the focus enhancement seen during workouts.
Choline Bitartrate (300mg)
Choline supplements are another one of our favorite focus enhancing agents. It helps give a more centered or “locked in” feel during your workouts. Additionally, it also helps establish a strong “mind-muscle” connection while lifting.
Usually we’d prefer to see between 500-1000mg of choline bitartrate in a pre workout, when it’s the sole focus boosting agent in a product. However, in combination with NALT and the other brain boosters ahead, this is plenty.
Caffeine Anhydrous (200mg)
We’re not going to waste a lot of time here with caffeine. Except to say that it’s the first of TWO forms of caffeine contained in Loaded. 200mg is a great amount for most users as it’s not too much, and it’s not too low.
It’s great for improving alertness, focus, and energy levels and will work wonders alongside the other stims still to come.
Theobromine comes from the Theobroma cacao plant. It’s most well known for lending the “feel-good” sensation you get when eating chocolate, particularly the really dark kind.
Theobromine is a xanthine-like molecule much like caffeine, and is sometimes dubbed caffeine’s younger brother. Similar to caffeine, theobromine acts as a mild stimulant in the body, though not to the extent that caffeine does. But, theobromine’s energy kick is much smoother and longer-lasting than it’s more famous brother.
Infinergy™ Dicaffeine Malate (75mg)
Our second form of caffeine comes in the form of dicaffeine malate, a combination of caffeine and malic acid that contains 73% caffeine by mass. This brings our total caffeine content to ~254.75mg, right in our personal “sweet spot.”
Infinergy is a buffered form of caffeine that eases the digestive effects of caffeine on the stomach, thanks to malic acid (malate). Additionally, it provides a much more sustained, and smoother ride up and down the caffeine high you get, which helps offset any potential crash some users may feel from high caffeine doses.
Hordenine HCl (50mg)
Hordenine is one of the many bioactive alkaloids (along with synephrine and octopamine) contained in the plant Citrus Aurantium (a.k.a. bitter orange). Like the other components found in the plant, hordenine functions as a beta-2 adrenergic agonist in the body which helps relax bronchial passages and increase vasodilation.
More importantly though, Hordenine also acts as a noradrenaline reuptake modulator.[21,22] Without getting too heavy into the science, hordenine helps noradrenaline stay active longer in your body which translates into increased energy, focus, and alertness.
N-Methyltyramine HCl (50mg)
N-Methyltyramine (NMT) is another beta-2 adrenergic agonist in the body. Basically, it stimulates the “fight or flight” response that helps harvest fatty acids for energy and increases adrenaline production.
Research has even shown that NMT is approximately 1/140th as potent as adrenaline, so you’ll definitely be riding “high” with all of the stims contained in Loaded, and we’re still not done!
Higenamine HCl (25mg)
Higenamine is yet another beta adrenergic like our previous 2 ingredients. Similar to the others, higenamine increases production of noradrenaline, which further strengthens “fight or flight” response. This all leads to heightened focus, greater concentration, and the drive to just want to “DO WORK!”
Given the cavalcade of stimulants, focus boosters, pump enhancers and endurance maximizers you’ll be consuming at one time, it’d help to ensure your body actually absorbs every last bit.
Black pepper extracts like Bioperine enhance the bioavailability and absorption of other ingredients in supplements due to its ability to prolong the duration these compounds stay intact in your body.d
Huperzine Serrata Extract (100mcg)
Our final ingredient is also a potent cognitive boosters Huperzine Serrate Extract, a.k.a.Toothed Clubmoss, standardized to 1% Huperzine A. Huperzine indirectly increases the body’s levels of the all-too-important neurotransmitter acetylcholine, as opposed to other nootropics that directly increase its production.
Huperzine inhibits the enzyme responsible for degrading acetylcholine in the body, acetylcholinesterase, which indirectly increases circulating levels of the potent focus aid.
Huperzine also supports overall brain health by preventing premature cell death caused by the neurotoxin glutamine and may potentially even help create new brain cells.[26,27]
At this time, there is only one flavor of Loaded available: Pineapple. So, if you’re intrigued by this product you better like tropical flavors!
Pumped Sports may be relatively unknown to the vast majority of our readers at this current time, but should they continue to release solid offerings like this, they’ll gain a foothold in the industry in short order.
Loaded packs quite a punch from the looks of it and will make for some rather impressive workouts. We’ve been lucky enough to get a hold of some and will be back in a while to give a full review. Stay Tuned!
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- Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
- Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
- Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training“
- Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
- Lee EC, et al. Ergogenic effects of betaine supplementation on strength and power performance. J Int Soc Sports Nutr. (2010)
- holewa, J; Effects of betaine on body composition, performance, and homocysteine thiolactone.; Department of Kinesiology, Recreation, and Sport Studies, Coastal Carolina University; 2013
- del Favero S, et al Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance . Amino Acids. (2012)
- Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise.
- Demady DR, et al. “Agmatine Enhances The NADPH Oxidase Activity Of Neuronal NO Synthase And Leads To Oxidative Inactivation Of The Enzyme. – Pubmed – NCBI”. Ncbi.nlm.nih.gov. N.p., 2016. Web. 28 Mar. 2016.
- Hoffmann, E.K., I.H. Lambert, and S.F. Pedersen, Physiology of cell volume regulation in vertebrates. Physiol Rev, 2009. 89(1)
- Proctor SD, Kelly SE, Russell JC. A novel complex of arginine-silicate improves micro- and macrovascular function and inhibits glomerular sclerosis in insulin-resistant JCR:LA-cp rats.Diabetologia. 2005 Sep;48(9):1925-32.
- Kalman D, Feldman S, Samson A, Krieger D. A clinical evaluation to determine the safety, pharmacokinetics and pharmacodynamics of an inositol-stabilized arginine silicate dietary supplement in healthy adult males. The FASEB Journal 2014;28(1):SLB418.
- Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
- Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
- Frank M, et al; Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse; Equine Vet J. (1990)
- Barwell C.; School of Pharmacy; “Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat;” 1989
- Nedergaard O.; British Journal of Pharmacology; “Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig;” November 1968
- Zhao, Q; Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; 2002