PWO-MAX: Prime Nutrition’s MONSTER Reformulation

Prime Nutrition PWO-MAX 2016

Prime Nutrition is returning to greatness with Hi-Tech at the helm and it’s first re-release is a charged up version of its pre workout PWO-MAX.

It’s been a wild year for Prime Nutrition, which went through some ownership turnover between Aaron Singerman and PJ Braun, but after Jared Wheat of Hi-Tech Pharma recently bought shares of Prime, things appear to be settling down now and the product line is moving forward.

The new tag-team of RedCon1‘s frontman Aaron Singerman and Wheat have wasted no time in completely overhauling the once fiery-hot brand, giving it a completely new look with cleaner labels for starters.

PWO-MAX: The first reformulated supplement from the new Prime Nutrition

On the supplement side of things, it was time to see what the newfound Prime Nutrition would bring us. The first reformulation is of the pre workout supplement, PWO-MAX, and let us tell you, Singerman and Wheat are coming out with a bang.

PWO-MAX with comes with two forms of caffeine and a whopping 75mg DMAA! As a bonus, the new pre is naturally flavored by stevia, and 100% free of all artificial colors, dyes, and artificial flavors! This is a mix of two worlds many haven’t seen before.

You can view the reformulation ingredients panel below, but first, take a moment to check the best deal and sign up for alerts from PricePlow:

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Note: In the price comparisons above, some of the old stock may still be in place. You’ll need to find the new formula of PWO-MAX, which has 75mg 1,3-Dimethylamylamine at the end of the label. Check each store for availability.

PWO-MAX 2016 Ingredients

Prime may be undergoing a massive rebrand, but the company’s previous commitment to full transparency on the label is still continuing as evidenced by the revamped PWO-MAX label, which looks to be packing a very well-dosed profiled, and a heaping 75mg DMAA!

  • Beta Alanine (3.2g)

    Prime Nutrition PWO-MAX 2016 Ingredients

    The 2016 version of PWO-MAX has been considerably upgraded from its predecessor and now boasts a powerful 75mg of DMAA along with 2 forms of caffeine!

    Beta Alanine is the well-known tingle-inducing amino acid used by athletes for of all sorts to improve endurance and stamina. Once ingested, beta alanine binds to histidine to form the powerful intracellular buffer carnosine.[1]

    In skeletal muscle, carnosine helps prevent lactic acid accumulation, which offsets the burning sensation that builds during extended working sets. This results in greater stamina, endurance, power and strength output for athletes, no matter their specialty.[2,3,4]

    The tingle factor may be strong with this one!

    Yes, this is the full clinical dose of BA in one sitting. While most studies split those doses across the day, PWO-MAX brings it all at once. We’re unsure if this is going to lead to the same results that were had in those studies, but one thing is for sure – if you’re susceptible to the beta alanine tingles, this may definitely bring a serious amount!

    One way to reduce the amount of tingles is to take this after eating a lot of carbs – but some who enjoy fasted training may not like that and will just need to dive into the tingles head-first.

  • Agmatine (2g)

    Agmatine and Arginine

    Agmatine is similar to arginine, but WAY better for our purposes.

    The first of two pump boosters included in PWO-MAX, Agmatine is a powerful indirect booster of nitric oxide. (N.O.). Basically, agmatine indirectly boosts N.O. levels by inhibiting arginase, the enzyme that breaks down Arginine.[5]

    Agmatine seems to be making a big comeback lately, and nothing says that more than a serious 2g dose. Most pre workouts show 500mg, and we typically enjoy 1-1.5g. A full 2g dose though is serious business, and it’s not even the only pump ingredient!

    The end results from this are “sharper”, longer-lasting pumps and more prolonged nitric oxide increases from our next ingredient which is…

  • Sodium Nitrate (1g)

    Nitrates are one of the most powerful nitric oxide boosters on the market, and have seen a significant increase in use in pre workouts over the last year and a half. The reason they’re so popular is the fact that they act as potent vasodilators[6,7], which improves blood flow and results in one hell of a pump. Additionally, they also support cardiovascular health by lowering blood pressure and protecting against endothelial dysfunction.[8,9]

    From a pure performance point of view, nitrates increase athletic exercise performance by lowering the oxygen cost of exercise and boosting energy efficiency during workouts.[10,11]

    There’s another great reason for nitrate: it helps lower blood pressure through the above mechanisms. While you may not always want that, we must admit that 75mg of DMAA has been shown to increase blood pressure[26] — and since that’s what is here in PWO-MAX, it’s wise to include something that seriously negates the one drawback of this dose of DMAA.

    Not to be mixed with certain prescription drugs!

    It goes without saying that this is a supplement that you do not take if you’re using erectile dysfunction medication or any other prescription drugs. Nitrates, when combined with certain ED drugs, can lower blood pressure so much that it’s absolutely hazardous.[25] The effect across these two is that strong.

    But when nitrates are used alone in an pre workout on healthy individuals, the pumps are out of this world.

  • N-Acetyl L-Tyrosine (750mg)

    Prime Nutrition Tweet Update

    Direct from the horse’s mouth, Prime will be testing all supplements and providing the proof to YOU, the valued consumer!

    N-Acetyl L-Tyrosine is a more stable and water-soluble form of the non-essential amino acid L-Tyrosine. This non-essential amino acid enhances production of two critical neurotransmitters in the body, dopamine and noradrenaline.[12] This tandem of neurotransmitters improves focus, cognition, and overall mood.

    Additional benefits from the increased production of these two neurotransmitters is decreased levels of stress and anxiety.[13,14] Not only does this help reduce feelings of “edginess” from stim overloads and stressful jobs (or families), but it provides for more focused, productive working sessions.

    When you have as much DMAA and agmatine as we have here, this is really the only focus compound you’d need, but PWO-MAX isn’t done yet:

  • Choline Bitartrate (500mg)

    Another staple cognitive enhancer is Choline which are much beloved for their ability to effectively increase focus and the always important “mind-muscle” connection.[15] The bitartrate form is one of the cheaper forms of choline due to its poorer bioavailability and absorption compared to more potent choline forms such as CDP Choline or Alpha GPC, meaning you’ll usually need a higher dose of bitartrate than either of the other two forms to feel the same effects.

    500mg is decent amount when used alongside another nootropic like NALT, but we feel this ingredient really stand out when we get closer to the 1g level.

  • Caffeine Citrate (200mg)

    The first form of caffeine included in PWO-MAX is one of the quickest acting forms of caffeine, caffeine citrate. Also known as CafCit, caffeine citrate only contains about 50% caffeine by mass[16], which yields 100mg of caffeine out of the 200mg dose included in the formula. This form of caffeine is most notably used for sleep apnea in preterm infants[17], we’re not entirely sure why it’s used in pre workouts though to be honest…

  • Caffeine Anhydrous (100mg)

    Our second form of caffeine is the much more common, and more beloved form, caffeine anhydrous. This is the fast-acting, hard hitting form we’re all familiar with from the scores of pre workouts and fat burners we’ve experimented with over the years. There’s not much to be said about this ingredient that you don’t already know, so suffice to say that we know you know what it is, and love it. All we’ll say is that the total amount of caffeine in each serving of PWO-MAX is 200mg.

  • DMAA (75mg)

    Hi-Tech Pharmaceuticals

    Hi-Tech’s role in Prime’s relaunch is no more evident than through the heaping dose of DMAA that’s been added to the new version of PWO-MAX.

    Displayed on the label as 1,3-Dimethylamylamine, DMAA is front and center on this profile in an incredibly potent 75mg per scoop! This is a heaping helping of the world’s best known aliphatic amine. It functions particularly well alongside caffeine, and according to various anecdotal reports also has a relatively noticeable appetite suppressant effect.

    If you’re one that typically is a bit wary of DMAA and it’s safety, that’s ultimately a personal decision, but just realize that there is plenty of research showing its safety with healthy individuals using reasonable doses[18,19,20,21,22,23,24] and many (if not all) accidents that occurred with it was due to abuse (i.e. “misuse) or not following the label.

    Combined with sodium nitrate = success

    Of course, it has to be mentioned that this dosage of DMAA has been shown to increase blood pressure[26] – but that’s why we’re so excited to see such a great dose of agmatine and nitrate to help negate that.

    This is yet another new or revamped Hi-Tech Family supplement that contains the controversial stim, to see all of Hi-Tech’s supplements with 1,3 head on over to our DMAA Supplements page.

Flavors Available

So far, the only flavor confirmed for the PWO-Max relaunch is Kiwi-Strawberry. We do expect a few other flavors to be added to the lineup once an exact release day, week, or month is confirmed by Prime and Hi-Tech. Until then, we just left to speculate on the possibilities!

No artificial colors, sweeteners, or flavors!

PWO-MAX

Out with the old, in with the new. The new PWO-MAX is not only hardcore with DMAA and nitrates, but it’s also ‘hardcore’ with stevia and no artificial sweeteners, flavors, or colors!

Interestingly, we’re seeing Prime Nutrition jump on a new trend here that was kicked into high gear with non-DMAA pre workouts like Transparent Labs Pre-Series BULK: no artificial sweeteners! This mean no sucralose, no aspartame, and no acesulfame potassium (ace-k)! To add to this, the flavors are also purely natural – so include no artificial flavors in that list as well.

We’ve seen many products that have no artificial colors (such as the entire RedCon1 line), but not as many are using only stevia as their sweetener like PWO-MAX here. This is a welcomed addition to the Jared Wheat line of products, and one thing we’re sure he’ll be monitoring to see if he wants to bring it to other product lines.

But the honest truth is we’d drink this stuff unflavored and unsweetened. We’re that excited about this profile. Having stevia just sweetens the pot.

Takeaway: The one we’ve been waiting for

Legit doses of Nitrates combined with DMAA – that alone is literally all we’ve wanted from these guys. But the new Prime Nutrition PWO-MAX has so much more than that.

Prime Nutrition

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PWO-MAX is a hard-hitting, incredibly potent energy and performance-based pre workout. Should you be able to handle the full 75mg of DMAA per scoop, you’ll be handsomely rewarded will some truly next-level focus and pumps during your workout. The 200mg dose of the caffeine may not seem impressive or even “hardcore” enough for some of you stim-fiends out there, but when paired alongside the power of 1,3, you’ll have all the energy you need (and then some) to really get after it in the weight room.

Meanwhile, this is the first naturally-sweetened product we’ve seen from the Hi-Tech / Jared Wheat family, and we’re excited to see how it works out. It’s an interesting mix of two different kinds of hardcore crowds – and those are two crowds that we are a part of and enjoy following.

This is a very intriguing first supplement for Prime’s relaunch, we’ll keep our eyes peeled to see what else is up for the brand in the coming weeks and months ahead. But in the meantime, this one we gotta try.

PWO-Max - Best Deals and Price Drop Notifications

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Note: In the price comparisons above, some of the old stock may still be in place. You’ll need to find the new formula of PWO-MAX, which has 75mg 1,3-Dimethylamylamine at the end of the label. Check each store for availability.

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References

  1. Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
  2. Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training
  3. Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
  4. Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
  5. Demady, D; Agmatine enhances the NADPH oxidase activity of neuronal NO synthase and leads to oxidative inactivation of the enzyme.; Department of Pharmacology, The University of Michigan Medical School; 2001
  6. Kukovetz, W; “Mechanism of vasodilation by nitrates: role of cyclic GMP.”; Cardiology; 1987; 74 Suppl 1:12-9; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/2886220
  7. Cosby, Kenyatta; “Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation”; Nature Medicine  9, 1498 – 1505; 2003; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/14595407
  8. Coles, Leah T, and Peter M Clifton; “Effect of Beetroot Juice on Lowering Blood Pressure in Free-Living, Disease-Free Adults: A Randomized, Placebo-Controlled Trial”; Nutrition Journal 11; 2012: 106; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/23231777
  9. Sindler, Amy L. et al; “Nitrite Supplementation Reverses Vascular Endothelial Dysfunction and Large Elastic Artery Stiffness with Aging”; Aging cell 10.3 429–437; 2011; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21276184
  10. Larsen, F; “Effects of dietary nitrate on oxygen cost during exercise”; Acta Physiol (Oxf). 2007 Sep;191(1):59-66; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17635415
  11. Lansley, K; “Dietary nitrate supplementation reduces the O2 cost of walking and running: a placebo-controlled study”; J Appl Physiol (1985). 2011 Mar;110(3):591-600; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21071588
  12. Yeghiayan SK, et al; Tyrosine improves behavioral and neurochemical deficits caused by cold exposure . Physiol Behav. (2001)
  13. Deijen JB, Orlebeke JF; Effect of tyrosine on cognitive function and blood pressure under stress . Brain Res Bull. (1994)
  14. Dollins AB, et al; L-tyrosine ameliorates some effects of lower body negative pressure stress . Physiol Behav. (1995)
  15. E. McGlade, A. Locatelli, J. Hardy, T. Kamiya, M. Morita, K. Morishita, Y. Sugimura and D. Yurgelun-Todd, “Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women,” Food and Nutrition Sciences, Vol. 3 No. 6, 2012, pp. 769-773. doi: 10.4236/fns.2012.36103. http://file.scirp.org/Html/8-2700397_19921.htm
  16. http://www.accessdata.fda.gov/drugsatfda_docs/label/2000/20793s1lbl.pdf
  17. Abdel-Hady H, Nasef N, Shabaan AE, Nour I. Caffeine therapy in preterm infants. World Journal of Clinical Pediatrics. 2015;4(4):81-93. doi:10.5409/wjcp.v4.i4.81. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637812/
  18. McCarthy CG, Farney TM, Canale RE et al; “A Finished Dietary Supplement Stimulates Lipolysis and Metabolic Rate in Young Men and Women”; Nutrition and Metabolic Insights 2012:5 23-31; Available athttps://blog.priceplow.com/wp-content/uploads/a-finished-dietary-supplement-stimulantes-lipolysis-and-metabolic-rate-in-young-men-and-women.pdf
  19. McCarthy CG, Canale RE, Alleman Jr. RJ et al; “Biochemical and Anthropometric Effects of a Weight Loss Dietary Supplement in Healthy Men and Women”; Nutrition and Metabolic Insights 2012:5 13-22; Available at https://blog.priceplow.com/wp-content/uploads/biochemical-and-anthropometric-effects-of-a-weight-loss-dietary-supplement-in-healthy-men-and-women.pdf
  20. Farney TM, McCarthy, CG, Canale R et al.; “Hemodynamic and Hematologic Profile of Healthy Adults Ingesting Dietary Supplements Containing 1,3-Dimethylamylamine and Caffeine”; Nutrition and Metabolic Insights; 2012:5 1-12; Available at https://blog.priceplow.com/wp-content/uploads/hemodynamic-and-hematologic-profile-of-healthy-adults-ingesting-dietary-supplements-containing-1-3-dimethylamylamine-and-caffeine.pdf
  21. Paul N. Whitehead, Brian K. Schilling, Tyler M. Farney, Richard J. Bloomer; “Impact of a Dietary Supplement Containing 1,3-Dimethylamylamine on Blood Pressure and Bloodborne Markers of Health: a 10-Week Intervention Study”; Nutrition and Metabolic Insights; 2012; Available at https://blog.priceplow.com/wp-content/uploads/impact-of-a-dietary-supplement-containing-1-3-dimethylamylamine-on-blood-pressure-and-bloodborne-markers-of-health-a-10-week-intervention-study.pdf
  22. Bloomer RJ, Schilling BK, Whitehead PN et al. Safety profile of a dietary supplement containing 1,3-dimethylamylamine: a 10-week intervention study. Nutrition and Metabolic Insights (In Press).
  23. Bloomer RJ, McCarthy CG, Farney TM et al.; “Effect of caffeine and 1,3-dimethylamylamine on exercise performance and blood markers of lipolysis and oxidative stress in trained men and women.” J Caffeine Res (In Press); Retrieved from http://online.liebertpub.com/doi/abs/10.1089/jcr.2011.0019
  24. Schilling, Brian, et al.; “Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men”; BMC Pharmacology and Toxicology; 2013; Retrieved from http://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/2050-6511-14-52
  25. Kloner, R; “Time course of the interaction between tadalafil and nitrates”; Journal of the American College of Cardiology; Volume 42, Issue 10, 19 November 2003, Pages 1855–1860; Retrieved from http://www.sciencedirect.com/science/article/pii/S0735109703012932
  26. Bloomer RJ, Harvey IC, Farney TM et al; “Effects of 1,3-dimethylamylamine and caffeine alone or in combination on heart rate and blood pressure in healthy men and women.”; Phys Sportsmed. 2011 Oct;39(3):111-120; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22030947 (original article archived at https://web.archive.org/web/20111102174432/http://www.physsportsmed.org/doi/10.3810/psm.2011.09.1927)
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