Primeval Labs was once known only as an under-the-radar hardcore brand, popular for a bevy of well-dosed prohormones. Recently though, the brand has been crushing it with their newer supplements that appeal to a much more diverse consumer base.
But it’s not just about aggressive muscle builders and stimulants. Nowhere is this more evident than with their incredibly effective and non-habit forming, sleep aid BIOS3 Xanix. Primeval is now turning their creative genius on a category of supplements in dire need of an effective product — stimulant-free fat burners.
Pyretic is a novel stim-free fat burner that incorporates some new age lipolytic agents alongside some of the most proven commodities around.
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Pyretic contains some ingredients that are very familiar to you, but what really sets it apart, are two vastly underutilized ingredients for weight loss aids — C3G & ITTP.
Acetyl L-Carnitine (500mg)
Acetyl L-Carnitine (ALCAR) is one of the most effective forms of carnitine available and possess the rare ability to cross the blood brain barrier (BBB). Due to this, ALCAR is able to reduce mental fatigue, improve mood, and enhance learning and cognition.[4,5]
More to the point of a its inclusion in a fat burner, ALCAR can increase “fatty acid dumping.” Here, fatty acids are excreted by the body when cells enter “fat burning mode.
Green Tea Extract (250mg)
Green tea has been consumed for thousands of years and is well known supporter of heart health. In addition to improving cardiovascular function, green tea also improves fat burning, primarily due to the powerful catechin EGCG.
Pyretic’s green tea extract is standardized for 50% EGCG, which is great, as EGCG promotes lipolysis in the body.[7,8]
Olea Europaea Leaf Extract 20% (150mg)
Commonly known as “European Olive”, Olea Europaea is a smaller species of the olive family prevalent throughout the Mediterranean. Olive leaf extract is frequently used in fat burners as a proven non-stimulant weight loss aide.
It’s been shown to improve insulin sensitivity and defend against LDL cholesterol oxidation, due in part to its high oleuropein content. Additionally, olive leaf extract elevates thyroid hormone, which is extremely beneficial during dieting.
In the clinical setting, even small doses of the extract have been shown to boost thyroid levels, leading to increased energy expenditure as well as improved markers of metabolic disorders like diabetes or obesity.
Coleus Forskohlii 20% (125mg)
When formulating an effective stimulant-free fat burner, including Coleus Forskohlii is a no-brainer. Forskolin is well documented in research to induce fat loss while simultaneously preserving, and even increasing, muscle mass in dieters.[11,12,13]
Forskolin works via increasing cAMP (cyclic adenosine monophosphate) levels in the body. Greater cAMP mimics the effects of exercise in terms of the action of mitochondrial enzymes in the body — elevating muscle protein synthesis in the body, which is great whether you’re cutting or recomping.
Cyanidin-3-Glucoside, C3G, is an ingredient rarely seen or even heard of in fat burners… until now.
C3G is an anthocyanidin found primarily in the skins and dark-colored regions of dark purple fruits and berries such as blackberries, blueberries and a few others. C3G helps to mobilize fatty acids (i.e. FAT) to be used as energy, while sparing glycogen.
On top of that, C3G has also been studied for its effects as an alpha-amylase inhibitor, one of the salivary enzymes in humans that assists with starch digestion. Basically, C3G will allow you to enjoy some carbs while dieting but your body won’t necessarily absorb all of the calories from them. (Don’t get out of control though, these things never work so well that you can eat an entire pizza…)
C3G is one of the primary reasons Pyretic sets itself apart from all the other non-stim fat burners on the market. It’ll support your performance in the gym and in the kitchen to maximize fat loss, build a slim physique, and reach your goals all without the use of stimulants.
Bacopa Monnieri (100mg)
Bacopa is nootropic herb frequently used for its mood-elevating effects on the body. Additionally, Bacopa improves cognitive function and helps combats feelings of stress and anxiety.[18,19]
Yes, you’ll no doubt feel a bit cranky and foggy-headed while dieting, and bacopa will help with that, but there’s another reason Bacopa is included in Pyretic.
Bacopa monnieri may enhance your weight loss efforts by helping boost production of the thyroid hormone T4. Increased thyroid hormones help raise metabolic rate which means you’re burning more calories each day — helping shed weight that much faster!
Myo-inositol-trispyrophosphate (ITPP) is another ingredient that’s new to many of you and another reason Pyretic is a game changer for stim-free burners.
ITTP can increase oxygen delivery to skeletal muscle, yielding significantly better performance in the gym and maximum calorie burn during workouts. Greater oxygen to working muscles improves cardiovascular performance, which translates over to better strength and performance.
Oxygenation is key – as we’ve noted in the past, when you lose weight, you lose it through your breath. Could there possibly be a connection with respect to improved oxygen delivery and overall improved metabolism? It’s possible, and can at least be a secondary effect of ITPP.
When it comes to losing weight, it’s always boils down to burning more calories each day than you require. Working out with greater intensity with increases caloric expenditure, leading to faster weight loss and better workouts.
Chromium Picolinate (200mcg)
Chromium Picolinate is very underused, and underappreciated, ingredient in fat burners that can assist with regulating blood sugar levels — which will help keep hunger cravings at bay. Stable blood sugars keep you more “even keeled” and less likely to ravenous periods where you can completely blow your diet.
Take 2 capsules in the morning and 2 capsules in the evening for a total of 4 capsules daily.
Stim-free fat burners are tough, and often ineffective, so we’re always on the lookout for new and exciting ingredients to power them up without getting you too powered up with stims.
Pyretic represents the next generation of stimulant free weight loss aids. It’s an advanced fat burner, performance booster, and endurance enhancer unlike anything released before. Primeval has been on a roll lately with their newer, more “mainstream” releases, and frankly we can’t wait to see what’s next!
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- Vermeulen RC, Scholte HR; Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. Psychosom Med. (2004)
- Parnetti L, et al; Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type . Eur J Clin Pharmacol. (1992)
- Soczynska JK, et al; Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders . Expert Opin Investig Drugs. (2008)
- Ando S, et al; Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats . J Neurosci Res. (2001)
- Sano M, et al; Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer’s disease . Arch Neurol. (1992)
- Sachan DS, Hongu N; Increases in VO2max and metabolic markers of fat oxidation by caffeine, carnitine, and choline supplementation in rats . J Nutr Biochem. (2000)
- The Effects of Epigallocatechin-3-Gallate on Thermogenesis and Fat Oxidation in Obese Men: A Pilot Study
- Effects of the long term ingestion of tea catechins on Energy Expenditure and Dietary fat oxidation in healthy subjects
- Costford SR, et al. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab. (2010)
- Tsuda T, et al. Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes. Biochem Biophys Res Commun. (2004) https://www.ncbi.nlm.nih.gov/pubmed/15003523
- Stough C, Lloyd J, Clarke J, Downey LA, Hutchison CW, Rodgers T, & Nathan PJ. (2001). The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology. 156(4), 481-4. https://www.ncbi.nlm.nih.gov/pubmed/11498727
- Rai D, Bhatia G, Palit G, Pal R, Singh S, & Singh HK. (2003). Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacology, Biochemistry, and Behavior. 75(4), 823-30. https://www.ncbi.nlm.nih.gov/pubmed/12957224
- Kar A, Panda S, & Bharti S. (2002). Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Journal of Ethnopharmacology. 81(2), 281-5. https://www.ncbi.nlm.nih.gov/pubmed/12065164
- Biolo A, Greferath R, Siwik DA, et al. Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(6):1926-1929. doi:10.1073/pnas.0812381106. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644140/
- Meerman, Ruben & Brown, Andrew; “When somebody loses weight, where does the fat go?”; Gastroenterological Tracts; November 2014; http://www.bmj.com/content/349/bmj.g7257