Innovative Labs Wicked Pre Workout: 70mg DMAA!!

Innovative Labs Wicked

DMAA is back with a vengeance in Wicked from Innovative Labs. 70mg DMAA + 300mg Caffeine will give you ALL the energy you can stand!

Even though there’s a breakout new stimulant in DHMA in 2016, an old stalwart is seeing a grand rebirth among supplement companies and consumers. Yep, you’ve guessed it…

DMAA, or 1,3 Dimethylamylamine, is back with a vengeance and it’s showing up in all sorts of pre workouts and fat burners be released, or re-released, to the masses.

Wicked from Innovative Labs is a DMAA-powered pre workout containing the largest dose of DMAA we’ve yet to see in a pre workout, and that’s not the only stim in there either!

Thankfully, Innovative Labs is allowing to disclose the main doses to you here:

The Wicked Pre Workout TL;DR

  • 300mg Caffeine (per two-scoop serving)
  • 70mg 1,3 Dimethylamylamine (DMAA) (per two-scoop serving)
  • Silicate-based pump ingredients
  • Large dose of creatine nitrate

Need we really say more?

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Wicked Ingredients

Unfortunately, Wicked’s ingredient breakdown is shrouded behind a prop blend. However, we do have confirmation that each serving (two scoops!) contains 300mg of caffeine and 70mg of DMAA. If you’re a stim junkie, this is right up your alley!

Let’s see what else awaits…

  • N.O. Amplification Matrix (5,000mg)

    • Beta Alanine

      Innovative Labs Wicked Ingredients

      If you’re interested in pumps, energy, and focus, you’ve come to the right place!

      Beta alanine is a staple ingredient that no athlete or weight lifter should really be without. Once it binds to histidine in the body, it forms the potent intracellular buffer carnosine.[1]

      Carnosine prevents lactic acid from accumulating in your muscles during physical activity. Aside from giving you a deep “burning” sensation in your muscles, lactic acid build up also induces fatigue and impairs performance. Buffering this build up increases your endurance, work capacity and strength levels.[2,3,4]

      The clinical dose is 3.2g to get the most of BA. If you’re not getting that here, then you’re probably getting a very close amount. We’d venture a guess you’re getting at least 2.5g worth.

      Note that in a similarly labeled product, APS Mesomorph (our top pre workout, which is a tad lighter than this with 65mg DMAA in a full scoop), the team does provide a full 3.2g beta alanine. So… this really might be the only BA you need.

    • Citrulline Silicate

      Citrulline Silicate is proprietary combination of L-Citrulline and silicate widely regarded to be a powerful nitric oxide booster. Citrulline has been shown to not only be absorbed by the body better than arginine, but it’s also a better N.O. booster than arginine.[5]

      Increased nitric oxide production lends a number of benefits to your workout including better athletic performance, strength, endurance, and best of all, PUMPS![6,7]

    • Red Wine Extract

      Red Wine

      Who knew red wine could be a pump enhancer? Wicked’s red wine extract is standardized for 30% glycerol. Hydration and pumps!
      Image courtesy WikiCommons

      You may be wondering why Red Wine Extract is included in a Nitric Oxide boosting complex. Well, Innovative Labs has interestingly standardized their Red Wine Extract 30% glycerol. This is slightly higher than glycerol monostearate (GMS) which usually contains at most 25% glycerol, with the remainder being made of saturated fats.

      Glycerol acts as strong cell volumizer in skeletal muscle helping pull additional water and nutrients into it, creating a state of “hyper-hydration.”[8] Additionally, the increased hydration results in greater endurance, fuller more rounded muscles, and “water-based” pumps.[9]

      The most popular extract in red wine – resveratrol – is also quite healthy, but we’re not sure if it’s what’s leftover in here. Either way, this ingredient a new addition to pre workout and we’re very interested to see how it plays out.

  • Anabolic Cell Volumizer (4,010mg)

    • Creatine Nitrate

      Here we have another cell-swelling, pump-inducing ingredient due to the nitrate content. We all know creatine is great for improving strength, lean mass, and cell volumization,[10,11,12] but let’s look at the nitrate part a little more.

      Nitrates are strong vasodilators in the body[13,14], leading to greater blood flow and nutrient delivery to your muscles. More blood flow means bigger, badder, and longer lasting pumps. As if that’s not enough, nitrates also increase athletic performance by reducing the body’s consumption of oxygen during bouts of intense exercise[16]

      Lastly, nitrate supplementation is heart-healthy as it helps to lower blood pressure[15] – which is especially useful because the DMAA can admittedly elevate it.

    • Taurine

      Taurine Molecule

      Taurine is one of the most abundant amino acids that helps draw water and nutrients into muscles that helps with endurance.

      Taurine, chemically shown as 2-aminoethanesulfonic acid, is a conditionally essential amino acid found mostly in the heart, brain, and skeletal muscle of the body.

      Taurine is another cell volumizing ingredient that draws water into your muscles,[17] giving them a more rounded look and compounding on the “water-based” pumps we mentioned with glycerol.

      Aside from greater endurance and stronger pumps, taurine also helps to reduce signs of DOMS[18] and may even improve focus, since large amounts of the amino acid reside in the brain.[19]

    • Agmatine Silicate

      Whereas Citrulline Silicate can be thought of as a nitric oxide booster, agmatine is a nitric oxide extender. Agmatine inhibits arginase[20], the enzyme responsible for arginine’s breakdown in the body. Less arginine means less nitric oxide, so agmatine indirectly boosts N.O. levels by prolonging the length of time arginine stays active.

      When used alongside pump inducers like Citrulline, agmatine helps provide stronger, denser, and longer-lasting pumps.

      Lastly, agmatine may also improve focus and cognition since it functions as a neuromodulator / neurotransmitter in the brain.[21]

    • N-(aminoiminomethyl)-beta-alanine

      More commonly known as Guanidinopropionic Acid, N-(aminoiminomethyl)-beta-alanine is an analogue of creatine monohydrate.

      Guanidinopropionic acid performs numerous benefits including:

      • improved insulin function,
      • greater weight loss,
      • better muscle contraction, and
      • enhanced creatine uptake.[22,23]

    Perhaps the coolest thing about this ingredient is that it makes muscles appear more prominent even if you don’t spend hours curling in the squat rack![24]

    • D-Ribose

      Nitric Oxide - Vasodilation During Training

      Hypothesized response of arteries to increased flow and shear stress following varying durations of exercise training

      Ribose is produced in the body from glucose. When D-Ribose is ingested it combines with adenine to form ATP, the main component of cellular energy. During exercise, ATP levels are rapidly drained due to the intense physical demands placed on the body.

      D-Ribose has been shown to be effective in quickly replenishing ATP stores after exhaustive bouts of exercise.[25,26]

      However, you’ll generally need greater amounts (5-15g) of D-Ribose than are contained in Wicked to see any appreciable effects from supplementation.

    • Creatinol-O-Phosphate

      In our opinion, Creatinol-O-Phosphate (COP) is a vastly underutilized ingredient throughout the supplement industry. Much like beta alanine, COP prevents the blood pH level in the muscle from dropping too low, thus creating an acidic environment which impairs muscle contraction.[27,28]

      Maintaining a more neutral pH level means your muscles keep firing on all cylinders allowing you to really push the envelop during your workouts.

      We’ve noticed an appreciable increase in strength when using other pre workouts that contain COP. We just wish more research was published on it…

  • Neurogenic Energizers (390mg)

    This is a downright serious product. We highly recommend you start at ½ serving (which is 1 scoop), and never more than one scoop in a 24-hour period!

    • Caffeine Anhydrous (300mg)

      Not much needs to be explained about caffeine. It’s the most heavily consumed drug in the world whether it be through coffee, tea, sodas, or pre workouts, caffeine is everywhere!!!

      Although the energy blend isn’t fully disclosed, we do have confirmation that each serving of Wicked contains 300mg of caffeine. This is a sizeable dose for most users, but if you can handle the heat, it’ll do wonders for your energy, focus, and endurance.[29,30]

    • DMAA (70mg)

      720px-Health_effects_of_caffeine

      Also known as methylhexanamine, DMAA is an aliphatic amine, a group of compounds widely regarded for their stimulating effects. It functions especially well when put alongside caffeine!

      The dose included here is a giant 70mg! We haven’t come across many other products that venture this high in doses, and this is for highly experienced, advanced users only. While DMAA may be a great focus and mood elevator, when dosed at 75mg, it’s been shown to actually increase blood pressure.[31]

      Based on this, we’d STRONGLY recommend you start with just a half serving of Wicked (one scoop) unless you are a seasoned DMAA user and regular high-stim user.

    • Histidine

      Histidine is the amino acid the joins with beta alanine to form the lactic acid buffer carnosine that we mentioned up top. Low levels of Histidine negatively impact plasma levels of carnosine, meaning you won’t be “buffering” lactic acid efficiently.

      To make sure your endurance and strength levels keep up, it’s important to have both histidine and beta alanine present in sufficient amounts so carnosine can be generated and replaced as needed.[32]

    • Rauwolfia Serpentina Extract

      Rauwolfia serpentina is most likely included as a source of rauwolscine, sometimes known as alpha-yohimbine. This is yet another potent stimulant used in small doses.

      While there isn’t much research on alpha-Y, most of it is on regular yohimbine, it is known to be a strong alpha-2 antagonist[33,34], which helps prevents fat storage.

Flavors Available

Innovative Labs

Click the image to see all Innovative Labs supplements on PricePlow – they also bring us the high-powered ephedra-based fat burners, HellFire EPH 150 and Black Mamba HyperRush!

Should you feel up to tackling the energy behemoth that is Wicked, you’ll be able to choose between two flavors: Grueling Grape and Punishing Punch.

Sure the flavors seem tame, but there’s nothing tame about the energy you’ll get from even one scoop of this product… let alone the max dose of two!

Takeaway

DMAA is definitely back – at least while Hi-Tech Pharma and the FDA settle their dispute, and it’s bringing all sorts of carnage with it. If you’ve tried a bunch of other high stim products and still not found that one that gets your motor running, Wicked from Innovative Labs may just be your answer.

70mg of DMAA along with 300mg of Caffeine and a sprinkling of Alpha Yohimbe adds up to one serious energy punch – this Wicked Pre Workout is no joke!

Again, it’s worth mentioning that you should start with ½ serving of this as it’s VERY strong. But, suffice to say, the energy blend is intriguing and should provide for some insane energy and focus during workouts.

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References

  1. Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
  2. Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
  3. Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training
  4. Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
  5. Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
  6. http://www.ncbi.nlm.nih.gov/pubmed/20386132
  7. http://www.ncbi.nlm.nih.gov/pubmed/22251130
  8. van Rosendal, S; Guidelines for glycerol use in hyperhydration and rehydration associated with exercise.; School of Human Movement Studies, The University of Queensland; 2010
  9. Wingo, J; Influence of a Pre-Exercise Glycerol Hydration Beverage on Performance and Physiologic Function During Mountain-Bike Races in the Heat; University of Connecticut, Department of Sport, Leisure, & Exercise Science; 2004
  10. Bemben, M; The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.; Neuromuscular Lab, Dept. Health & Exercise Science, U. Oklahoma; 2010
  11. Chilibeck, P; Effect of creatine ingestion after exercise on muscle thickness in males and females.; College of Kinesiology, University of Saskatchewan; 2004
  12. Hoffman, J; Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes.; Dept. of Health and Exercise Science, The College of New Jersey; 2006
  13. Cardiology. 1987;74 Suppl 1:12-9.
  14. Nat Med. 2003 Dec;9(12):1498-505. Epub 2003 Nov 2.
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  16. Acta Physiol (Oxf). 2007 Sep;191(1):59-66. Epub 2007 Jul 17
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  18. http://www.ncbi.nlm.nih.gov/pubmed/24383513
  19. Alford, C., H. Cox, and R. Wescott, The effects of red bull energy drink on human performance and mood. Amino Acids, 2001. 21(2)
  20. http://www.ncbi.nlm.nih.gov/pubmed/11125020
  21. Lu Y, Christian K, Lu B; BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory . Neurobiol Learn Mem. (2008)
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  23. Vaillancourt VA, Larsen SD, Tanis SP, Burr JE, Connell MA, Cudahy MM, Evans BR, Fisher PV, May PD, Meglasson MD, Robinson DD, Stevens FC, Tucker JA, Vidmar TJ, Yu JH. Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid. J Med Chem. 2001 Apr 12;44(8):1231-48.
  24. Ohira Y, Kawano F, Roy RR, Edgerton VR. Metabolic modulation of muscle fiber properties unrelated to mechanical stimuli. Jpn J Physiol. 2003 Dec;53(6):389-400.
  25. Hellsten Y1, Skadhauge L, Bangsbo J; Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans . Am J Physiol Regul Integr Comp Physiol. (2004)
  26. Brault JJ1, Terjung RL; Purine salvage to adenine nucleotides in different skeletal muscle fiber types . J Appl Physiol (1985). (2001)
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  34. http://www.ncbi.nlm.nih.gov/pubmed/8517875
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