Innovative Labs Wicked Pre Workout: 70mg DMAA!!

Innovative Labs Wicked

DMAA is back with a vengeance in Wicked from Innovative Labs. 70mg DMAA + 300mg Caffeine will give you ALL the energy you can stand!

Even though there’s a breakout new stimulant in DHMA in 2016, an old stalwart is seeing a grand rebirth among supplement companies and consumers. Yep, you’ve guessed it…

DMAA, or 1,3 Dimethylamylamine, is back with a vengeance and it’s showing up in all sorts of pre workouts and fat burners be released, or re-released, to the masses.

Wicked from Innovative Labs is a DMAA-powered pre workout containing the largest dose of DMAA we’ve yet to see in a pre workout, and that’s not the only stim in there either!

Thankfully, Innovative Labs is allowing to disclose the main doses to you here:

The Wicked Pre Workout TL;DR

  • 300mg Caffeine (per two-scoop serving)
  • 70mg 1,3 Dimethylamylamine (DMAA) (per two-scoop serving)
  • Silicate-based pump ingredients
  • Large dose of creatine nitrate

Need we really say more?

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Wicked Ingredients

Unfortunately, Wicked’s ingredient breakdown is shrouded behind a prop blend. However, we do have confirmation that each serving (two scoops!) contains 300mg of caffeine and 70mg of DMAA. If you’re a stim junkie, this is right up your alley!

Let’s see what else awaits…

  • N.O. Amplification Matrix (5,000mg)

    • Beta Alanine

      Innovative Labs Wicked Ingredients

      If you’re interested in pumps, energy, and focus, you’ve come to the right place!

      Beta alanine is a staple ingredient that no athlete or weight lifter should really be without. Once it binds to histidine in the body, it forms the potent intracellular buffer carnosine.[1]

      Carnosine prevents lactic acid from accumulating in your muscles during physical activity. Aside from giving you a deep “burning” sensation in your muscles, lactic acid build up also induces fatigue and impairs performance. Buffering this build up increases your endurance, work capacity and strength levels.[2,3,4]

      The clinical dose is 3.2g to get the most of BA. If you’re not getting that here, then you’re probably getting a very close amount. We’d venture a guess you’re getting at least 2.5g worth.

      Note that in a similarly labeled product, APS Mesomorph (our top pre workout, which is a tad lighter than this with 65mg DMAA in a full scoop), the team does provide a full 3.2g beta alanine. So… this really might be the only BA you need.

    • Citrulline Silicate

      Citrulline Silicate is proprietary combination of L-Citrulline and silicate widely regarded to be a powerful nitric oxide booster. Citrulline has been shown to not only be absorbed by the body better than arginine, but it’s also a better N.O. booster than arginine.[5]

      Increased nitric oxide production lends a number of benefits to your workout including better athletic performance, strength, endurance, and best of all, PUMPS![6,7]

    • Red Wine Extract

      Red Wine

      Who knew red wine could be a pump enhancer? Wicked’s red wine extract is standardized for 30% glycerol. Hydration and pumps!
      Image courtesy WikiCommons

      You may be wondering why Red Wine Extract is included in a Nitric Oxide boosting complex. Well, Innovative Labs has interestingly standardized their Red Wine Extract 30% glycerol. This is slightly higher than glycerol monostearate (GMS) which usually contains at most 25% glycerol, with the remainder being made of saturated fats.

      Glycerol acts as strong cell volumizer in skeletal muscle helping pull additional water and nutrients into it, creating a state of “hyper-hydration.”[8] Additionally, the increased hydration results in greater endurance, fuller more rounded muscles, and “water-based” pumps.[9]

      The most popular extract in red wine – resveratrol – is also quite healthy, but we’re not sure if it’s what’s leftover in here. Either way, this ingredient a new addition to pre workout and we’re very interested to see how it plays out.

  • Anabolic Cell Volumizer (4,010mg)

    • Creatine Nitrate

      Here we have another cell-swelling, pump-inducing ingredient due to the nitrate content. We all know creatine is great for improving strength, lean mass, and cell volumization,[10,11,12] but let’s look at the nitrate part a little more.

      Nitrates are strong vasodilators in the body[13,14], leading to greater blood flow and nutrient delivery to your muscles. More blood flow means bigger, badder, and longer lasting pumps. As if that’s not enough, nitrates also increase athletic performance by reducing the body’s consumption of oxygen during bouts of intense exercise[16]

      Lastly, nitrate supplementation is heart-healthy as it helps to lower blood pressure[15] – which is especially useful because the DMAA can admittedly elevate it.

    • Taurine

      Taurine Molecule

      Taurine is one of the most abundant amino acids that helps draw water and nutrients into muscles that helps with endurance.

      Taurine, chemically shown as 2-aminoethanesulfonic acid, is a conditionally essential amino acid found mostly in the heart, brain, and skeletal muscle of the body.

      Taurine is another cell volumizing ingredient that draws water into your muscles,[17] giving them a more rounded look and compounding on the “water-based” pumps we mentioned with glycerol.

      Aside from greater endurance and stronger pumps, taurine also helps to reduce signs of DOMS[18] and may even improve focus, since large amounts of the amino acid reside in the brain.[19]

    • Agmatine Silicate

      Whereas Citrulline Silicate can be thought of as a nitric oxide booster, agmatine is a nitric oxide extender. Agmatine inhibits arginase[20], the enzyme responsible for arginine’s breakdown in the body. Less arginine means less nitric oxide, so agmatine indirectly boosts N.O. levels by prolonging the length of time arginine stays active.

      When used alongside pump inducers like Citrulline, agmatine helps provide stronger, denser, and longer-lasting pumps.

      Lastly, agmatine may also improve focus and cognition since it functions as a neuromodulator / neurotransmitter in the brain.[21]

    • N-(aminoiminomethyl)-beta-alanine

      More commonly known as Guanidinopropionic Acid, N-(aminoiminomethyl)-beta-alanine is an analogue of creatine monohydrate.

      Guanidinopropionic acid performs numerous benefits including:

      • improved insulin function,
      • greater weight loss,
      • better muscle contraction, and
      • enhanced creatine uptake.[22,23]

    Perhaps the coolest thing about this ingredient is that it makes muscles appear more prominent even if you don’t spend hours curling in the squat rack![24]

    • D-Ribose

      Nitric Oxide - Vasodilation During Training

      Hypothesized response of arteries to increased flow and shear stress following varying durations of exercise training

      Ribose is produced in the body from glucose. When D-Ribose is ingested it combines with adenine to form ATP, the main component of cellular energy. During exercise, ATP levels are rapidly drained due to the intense physical demands placed on the body.

      D-Ribose has been shown to be effective in quickly replenishing ATP stores after exhaustive bouts of exercise.[25,26]

      However, you’ll generally need greater amounts (5-15g) of D-Ribose than are contained in Wicked to see any appreciable effects from supplementation.

    • Creatinol-O-Phosphate

      In our opinion, Creatinol-O-Phosphate (COP) is a vastly underutilized ingredient throughout the supplement industry. Much like beta alanine, COP prevents the blood pH level in the muscle from dropping too low, thus creating an acidic environment which impairs muscle contraction.[27,28]

      Maintaining a more neutral pH level means your muscles keep firing on all cylinders allowing you to really push the envelop during your workouts.

      We’ve noticed an appreciable increase in strength when using other pre workouts that contain COP. We just wish more research was published on it…

  • Neurogenic Energizers (390mg)

    This is a downright serious product. We highly recommend you start at ½ serving (which is 1 scoop), and never more than one scoop in a 24-hour period!

    • Caffeine Anhydrous (300mg)

      Not much needs to be explained about caffeine. It’s the most heavily consumed drug in the world whether it be through coffee, tea, sodas, or pre workouts, caffeine is everywhere!!!

      Although the energy blend isn’t fully disclosed, we do have confirmation that each serving of Wicked contains 300mg of caffeine. This is a sizeable dose for most users, but if you can handle the heat, it’ll do wonders for your energy, focus, and endurance.[29,30]

    • DMAA (70mg)

      720px-Health_effects_of_caffeine

      Also known as methylhexanamine, DMAA is an aliphatic amine, a group of compounds widely regarded for their stimulating effects. It functions especially well when put alongside caffeine!

      The dose included here is a giant 70mg! We haven’t come across many other products that venture this high in doses, and this is for highly experienced, advanced users only. While DMAA may be a great focus and mood elevator, when dosed at 75mg, it’s been shown to actually increase blood pressure.[31]

      Based on this, we’d STRONGLY recommend you start with just a half serving of Wicked (one scoop) unless you are a seasoned DMAA user and regular high-stim user.

    • Histidine

      Histidine is the amino acid the joins with beta alanine to form the lactic acid buffer carnosine that we mentioned up top. Low levels of Histidine negatively impact plasma levels of carnosine, meaning you won’t be “buffering” lactic acid efficiently.

      To make sure your endurance and strength levels keep up, it’s important to have both histidine and beta alanine present in sufficient amounts so carnosine can be generated and replaced as needed.[32]

    • Rauwolfia Serpentina Extract

      Rauwolfia serpentina is most likely included as a source of rauwolscine, sometimes known as alpha-yohimbine. This is yet another potent stimulant used in small doses.

      While there isn’t much research on alpha-Y, most of it is on regular yohimbine, it is known to be a strong alpha-2 antagonist[33,34], which helps prevents fat storage.

Flavors Available

Innovative Labs

Click the image to see all Innovative Labs supplements on PricePlow – they also bring us the high-powered ephedra-based fat burners, HellFire EPH 150 and Black Mamba HyperRush!

Should you feel up to tackling the energy behemoth that is Wicked, you’ll be able to choose between two flavors: Grueling Grape and Punishing Punch.

Sure the flavors seem tame, but there’s nothing tame about the energy you’ll get from even one scoop of this product… let alone the max dose of two!

Takeaway

DMAA is definitely back – at least while Hi-Tech Pharma and the FDA settle their dispute, and it’s bringing all sorts of carnage with it. If you’ve tried a bunch of other high stim products and still not found that one that gets your motor running, Wicked from Innovative Labs may just be your answer.

70mg of DMAA along with 300mg of Caffeine and a sprinkling of Alpha Yohimbe adds up to one serious energy punch – this Wicked Pre Workout is no joke!

Again, it’s worth mentioning that you should start with ½ serving of this as it’s VERY strong. But, suffice to say, the energy blend is intriguing and should provide for some insane energy and focus during workouts.

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References

  1. Hill, CA et al.; Amino Acids; “Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity ;” February 2007
  2. Baguet, A et al.; Journal of Applied Physiology; “Important role of muscle carnosine in rowing performance;” July 2010;” 2005
  3. Roger C. Harris; et al.; “The effect of a supplement containing β-alanine on muscle carnosine synthesis, ventilatory threshold and exercise capacity in Korean cyclists, during 12 weeks combined endurance and weight training
  4. Kendrick IP, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids. (2008)
  5. Curis E., et. al; “Citrulline and the gut;”; Current Opinion in Clinical Nutrition and Metabolic Care; September 2007
  6. http://www.ncbi.nlm.nih.gov/pubmed/20386132
  7. http://www.ncbi.nlm.nih.gov/pubmed/22251130
  8. van Rosendal, S; Guidelines for glycerol use in hyperhydration and rehydration associated with exercise.; School of Human Movement Studies, The University of Queensland; 2010
  9. Wingo, J; Influence of a Pre-Exercise Glycerol Hydration Beverage on Performance and Physiologic Function During Mountain-Bike Races in the Heat; University of Connecticut, Department of Sport, Leisure, & Exercise Science; 2004
  10. Bemben, M; The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.; Neuromuscular Lab, Dept. Health & Exercise Science, U. Oklahoma; 2010
  11. Chilibeck, P; Effect of creatine ingestion after exercise on muscle thickness in males and females.; College of Kinesiology, University of Saskatchewan; 2004
  12. Hoffman, J; Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes.; Dept. of Health and Exercise Science, The College of New Jersey; 2006
  13. Cardiology. 1987;74 Suppl 1:12-9.
  14. Nat Med. 2003 Dec;9(12):1498-505. Epub 2003 Nov 2.
  15. Nutr J. 2012 Dec 11;11:106. doi: 10.1186/1475-2891-11-106.
  16. Acta Physiol (Oxf). 2007 Sep;191(1):59-66. Epub 2007 Jul 17
  17. Hoffmann, E.K., I.H. Lambert, and S.F. Pedersen, Physiology of cell volume regulation in vertebrates. Physiol Rev, 2009. 89(1)
  18. http://www.ncbi.nlm.nih.gov/pubmed/24383513
  19. Alford, C., H. Cox, and R. Wescott, The effects of red bull energy drink on human performance and mood. Amino Acids, 2001. 21(2)
  20. http://www.ncbi.nlm.nih.gov/pubmed/11125020
  21. Lu Y, Christian K, Lu B; BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory . Neurobiol Learn Mem. (2008)
  22. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052879
  23. Vaillancourt VA, Larsen SD, Tanis SP, Burr JE, Connell MA, Cudahy MM, Evans BR, Fisher PV, May PD, Meglasson MD, Robinson DD, Stevens FC, Tucker JA, Vidmar TJ, Yu JH. Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid. J Med Chem. 2001 Apr 12;44(8):1231-48.
  24. Ohira Y, Kawano F, Roy RR, Edgerton VR. Metabolic modulation of muscle fiber properties unrelated to mechanical stimuli. Jpn J Physiol. 2003 Dec;53(6):389-400.
  25. Hellsten Y1, Skadhauge L, Bangsbo J; Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans . Am J Physiol Regul Integr Comp Physiol. (2004)
  26. Brault JJ1, Terjung RL; Purine salvage to adenine nucleotides in different skeletal muscle fiber types . J Appl Physiol (1985). (2001)
  27. Gaggino R, Delfino C, Menichetti G, Odaglia G, Metabolic aspects of anaerobic lactaid maximal sport performances. Effect of treatment with Creatinol O-Phosphate. Medicina dello sport. 1984; 37: 85-92.
  28. De Gasperi R, Giusti V, Rapelli S, Matriadonna C. Influenza del creatinolo o-fosfato sulla contrazione muscolare aspettin biochimica. Archivio Medicina interna. 1981; 3: 351-358
  29. http://www.ncbi.nlm.nih.gov/pubmed/22124354
  30. http://www.ncbi.nlm.nih.gov/pubmed/23899750
  31. Bloomer, RJ, et. al; “Effects of 1,3-dimethylamylamine and caffeine alone or in combination on heart rate and blood pressure in healthy men and women“; The Physician and Sportsmedicine; September 2011
  32. Salah, E, Garbilla, Alan j. Sinclair, Carnosine: physiological properties and therapeutic potential. Age and Ageing; 2000; 29: 207-210
  33. http://www.ncbi.nlm.nih.gov/pubmed/6276200
  34. http://www.ncbi.nlm.nih.gov/pubmed/8517875
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  • Truth Speaker

    DMAA is illegal to sell as a dietary supplement, period. Regardless of whether synthetic DMAA meets the definition of a dietary ingredient, there has been no ndi notification filed and worse, DMAA is an approved drug, which makes it illegal to sell as a dietary supplement.

    It is prohibited under section 301(ll) of the Act (21 U.S.C. 331(ll)) to introduce or deliver for introduction into interstate commerce any food to which a drug approved under section 505 of the Act (21 U.S.C. 355) has been added, unless the added drug was marketed in food before being approved under section 505. DMAA was approved as a drug in 1948 under section 505 of the Act, and DMAA was not marketed in food prior to its approval as a drug. Any product containing DMAA is in violation of section 301(ll) of the Act and is illegal to sell as a dietary supplement.

    • jared wheat

      The “half Truth Speaker” RK is wrong as usual. First and foremost, however, DMAA is not an “illegal” ingredient as stated by the Patent Troll (RK). The Food and Drug Administation C’FDA”) has a comprehensive regulatory scheme, which includes procedures by which the Agency can take a dietary supplement ingredient off of the market. The banning of ephedrine alkaloids is a well-known example of the FDA’S exercise of this procedure. The FDA, however, has not followed such a procedure with respect to DMAA,rendering it a legal, albeit apparently controversial, ingredient. Hi-Tech is currently engaged in litigation with the FDA over this issue, to include the FDA’s failure to follow its own procedure.The FDA has taken the position that it need not follow its procedure for banning dietary supplement ingredients, arguing that DMAA is not subject to dietary supplement regulation.Specifically, the FDA argues that DMAA does not occur in nature and, therefore, is not subject
      to procedures applicable to dietary supplemen8. DMAA, however, can be found in the Geranium plant, as has been shown through scientific studies, and the concentration of DMAA in Geranium is irrelevant to the analysis of this issue under the Dietary Supplement Health and Education Act of 1994.
      Hi-Tech is confident it has taken the correct position and that it will prevail in this litigation. Given the fact that DMAA is nor “illegal,” and in light of the post by a very untrustworthy/biased source (RK) Hi-Tech felt the need to set the record straight.

      • Truth Speaker

        As usual the uninformed are wrong again. It is not even relevant in the case of DMAA whether or not it is found in geranium. The FDA is correct that it is not subject to dietary supplement regulation because it is a DRUG. DMAA was approved as a drug in 1948 under section 505 of the Act. This FACT alone makes DMAA ILLEGAL to sell as a dietary supplement.

        Show me any evidence where DMAA was marketed in food prior to its approval as a drug in 1948? You can’t because it never happened!

        How many drugs are going to continually be illegally sold as dietary supplements? Want to talk about BMPEA too? Also illegal, since it does not meet the definition of being a dietary ingredient. BMPEA is NOT found in any plant anywhere – there is not a single scientific reference to support it.

      • jared wheat

        Sounds like a company/ person who was unsuccessful with the Thermolife brand who has now turned into an unsuccessful patent troll as well! Be glad to talk about any herbal extract including beta-Methylphenylethylamine as it is found in many plants including Acacia species. However, would be more interesting to talk about you being a rat and “working your little fingers to the bone” as an informant…..want to open that up for discussion half truth speaker?

      • Truth Speaker

        You have failed to address any of the facts regarding DMAA being approved as a drug. Typical actions of the ignorant.

        Beta-Methyl PEA is not found in any species of Acacia, period. There is not a single scientific reference anywhere that shows Beta-Methyl in any species of Acacia or being found in any other botanical source. It is not a natural compound. Every reference EVER given shows N-Methyl PEA and NOT Beta-Methyl PEA. Do you even understand the different positions of the methyl group?? There is not a single reference anywhere that shows Beta-Methyl as naturally occurring.

        The truth does not cease to exist just because it’s ignored.

      • jared wheat

        I certainly understand the difference in the different positions of the methyl groups and I am very informed on the science of all PEA alkaloids as we were the first to bring them to market in 2003. You obviously are misinformed as you have been the multiple times we invalidated your bogus patents….. Speaking of— truth does not cease to exist just because it’s ignored—it seems you sidestepped the informant/rat fact. You should just embrace it as you are the Truth Speaker and people would respect you more.

      • Truth Speaker

        Again you fail to address the fact that DMAA was approved as a drug in 1948 which makes it illegal to sell as a dietary supplement. Prove me wrong. You can’t!

        Show me the reference where Beta-Methyl PEA is naturally found in any species of Acacia. You can’t!

        The truth will ultimately prevail where there is pains taken to bring it to light!

      • jared wheat

        With your logic ephedrine alkaloids found in Mahuang would have never been legal….The manufacture of ephedrine began in the 1920s, when Merck began marketing and selling the drug. In the 1940s, doctors began to prescribe it more aggressively for asthma—synephrine was “advertised as an antihistaminic to be used in the treatment of the common cold as far back as the 1930’s by Boehringer — surely you are not suggesting it is illegal also. And as for Yohimbine it is certainly illegal by your interpretation…. You sound like the quack Dr. Pieter Cohen from Harvard who would have all supplements banned. You may want to back off that stance as then your Patent racket would be shut down. In any event there are many other examples such as: In 1911, the U.S. government initiated United States V. Forty Barrels and Twenty Kegs of Coca-Cola, hoping to force Coca-Cola to remove caffeine from its formula. The case was decided in favor of Coca-Cola. The end result will be the same for Hi-Tech and DMAA will not be banned much like caffeine was saved from the Gestapo. I did notice you sidestepped the informant issue.

      • Truth Speaker

        Ha ha, ignorance is bliss at Lo-Tech! The FDA already sent a Warning Letter regarding Synephrine:

        “To the best of FDA’s knowledge, there is no information demonstrating that Bitter Orange Extract (synephrine 30%) was lawfully marketed as a dietary ingredient in the United States before October 15, 1994, nor is there information demonstrating that this ingredient has been present in the food supply as an article used for human food in a form in which the food has not been chemically altered.”

        If a 30% Synephrine Extract requires an ndi notification in order to be legally sold as a dietary supplement, then it’s a sure bet that synthetic Synephrine requires an ndi notification too!

        You are still ignoring the FACT that BMPEA is not found in any species of Acacia even though you would be glad to talk about it earlier. As soon as you found out that the fraudulent method of using references that show N-Methyl PEA in plants is not the same as Beta-Methyl PEA (which is not found in plants!) would not pass mustard here – crickets!

        The truth is the truth is the truth!

      • jared wheat

        Hate to prove the rat wrong…..again! We had a shipment of citrus aurantium 30% detained at customs 9 months ago with the same nonsensical argument. However, we challenged FDA and Department of Justice stating that we had been importing synephrine alkaloids since 1997 and if they wanted another fight like the one on DMAA we would gladly take up that fight. Luckily the powers to be in Washington “saw the light” and released our goods and we have since imported the material half a dozen times. I know the “half truth speaker” has never fought a case in his life and would rather “cooperate with the government” rather than put them to task when they are wrong……but sometimes you must stand your ground and do not let bullies or patent troll like RK win. AND IN NO CASE IS IT RIGHT TO BECOME AN INFORMANT AND TELL ON OTHER PEOPLE TO LESSEN THE JAIL TIME FOR A BAD DECISION MADE….YOU EITHER SHOULD FIGHT IF WRONGLY ACCUSED OR TAKE YOU MEDICINE, WHICH IS SOMETHING RK/THERMOLIFE HAS NEVER DONE IN THEIR EXISTENCE.