We’ve been on top of the burgeoning energy aminos market for some time now. What started out as a niche category in the amino acid supplements market is now expanding into its own full blown category with entries from all the big players in the game.
Hi-Tech Pharmaceuticals is the latest industry giant to jump into the fray with an energized amino acid product, but theirs is much more interesting.
Off the Chain not only couples amino acids with caffeine, but also packs a special punch with the addition of a dash of DMAA! Don’t worry, there’s a non-DMAA option as well, but that one wouldn’t be as much fun.
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Our Off the Chain Review
CJ gave this to nearly everyone at the gym, and everyone concurred: this stuff is AWESOME!!
For whatever reason, we’re honestly liking this better as a pre workout than even Jack’d Up! The energy is just so perfectly blended. Read why below in our ingredient analysis:
Off the Chain Ingredients
As we mentioned before the break, Off the Chain comes in both a DMAA and DMAA-free option. The breakdown below is for the option that includes DMAA. Now, onto the goods!
Amino Blend (5g)
Off the Chain contains a blend of 13 amino acids, not just branched-chain amino acids (BCAAs).
Leading off the blend is Ajinomoto micronized L-Glutamine, followed by the three BCAAs (Leucine, Isoleucine, and Valine). Also included are a dash of Arginine, Citrulline, Tyrosine, Taurine, Histidine, Phenylalanine, Threonine, and Methionine.
Now, we’d prefer to really just have 5g dose of BCAAs, instead of a cavalcade of conditionally essential amino acids, to really drive muscle protein synthesis and recovery. [1,2] But, let’s be honest here. Anyone purchasing this product is probably getting it mainly for DMAA’s mood, focus, and performance enhancement, not the amino acid content. Fair is fair.
Energy Blend (160mg)
Here’s where Off the Chain makes its money, energy blend. Hi-Tech was kind enough to disclose just how much caffeine and DMAA are included in each serving of Off the Chain.
Caffeine Anhydrous (100mg)
Off the Chain includes the perfect amount of caffeine for a middle of the afternoon pick me up or a mild energy boost during a particularly intense workout. 100mg is right around how much you’d get in your standard 8 oz. cup of drip coffee.
Now, if you burnt out on drinking the flavorless swill in the office breakroom, simply mix up a serving of this, and you’ll be well on your way to avoiding the afternoon lull.
This right here is what separates Off the Chain from every other energy amino product on the market. Good old Methylhexanamine HCl, a.k.a. 1,3 dimethylamylamine, or DMAA.
DMAA is an aliphatic amine widely regarded for its stimulating and mood-elevating effects. It functions particularly well alongside caffeine. Anecdotally, DMAA also has a relatively decent appetite suppressant effect, which helps quash those hunger cravings hardcore dieters may get.
Should you not tolerate DMAA well, or want to avoid it entirely, don’t worry you can opt for the DMAA-free option and still enjoy the benefits of aminos and caffeine.
As to whether you’ll want to try DMAA, it’s really up to you. There is plenty of research showing its safety with healthy individuals using reasonable doses,[7,8,9,10,11,12,13] and many (if not all) accidents that occurred with it was due to misuse and not following the label.
DMAA’s legality is heading to court
In case this is your first time here, note that Hi-Tech Pharmaceuticals is practically the only company selling DMAA, as the FDA has discouraged its sales through warning letters.
Hi-Tech consistently argues that 1,3 is naturally-occurring in geranium stems,[14,15,16] and that the FDA’s warning letters are without legal merit and do not constitute as “final agency action”. Because of this, Hi-Tech is suing the FDA over DMAA, a case which we’re following closely and should head to court this year.
Until then, they are selling these products, and we encourage responsible use – don’t mix it with other stimulant-based products. The fact that Off the Chain is a light dose compared to other products makes it a great choice for anyone considering starting.
Our personal and safe sweet spot is around 35-50mg, so give one scoop a shot, and if you like it, you can max out at two and still be in a good range.
You can see all of Hi-Tech’s supplements with 1,3 on our DMAA Supplements page.
Green Tea Extract
The last bit of energy comes from Green Tea extract. Green tea has long been known for its beneficial effects on the cardiovascular system, due to its high polyphenol and catechin content, EGCG among those.
It’s also beneficial for fat burning in part thanks to EGCG’s role in promoting lipolytic actions in the body.[3,4] There’s also a mild energy boost from the small amount of caffeine included in green tea, but the majority of the energy you’ll feel from Off the Chain is due to the previous two ingredients.
Off the Chain is now up to four flavors!
- Blue Raspberry
- Pink Lemonade
- Rocket Pop
- Strawberry Kiwi
After Blue Raspberry and Pink Lemonade were released in March, Off the Chain flew off the shelves and Hi-Tech came through on their promise for more flavors. We’re excited to announce the new flavors in May, Rocket Pop and Strawberry Kiwi!
Rocket Pop is also often known as “blue bombsicle”, popular for the multi-colored red, white, and blue popsicles we used to get as kids!
Hey Hi-Tech – Bring on that rocket pop! (Update: MISSION ACCOMPLISHED)
We suspect a Watermelon flavor should be on the way at some point, as well as a Rocket Pop, since those are both incredibly popular in other Hi-Tech Family products like Jack’d Up and Mesomorph (both of which also have DMAA in disclosed doses).
Need a kick of energy but not a “kick-in-the-face’s” worth of energy? This is the perfect balance and just what we look for in an afternoon go-getter. No more needing to take a partial scoop of Jack’d Up to get some work done – turn your afternoon slump into an afternoon that’s Off the Chain!
Off the Chain ushers in a new and exciting twist on the standard energy amino supplement. Not only do you get a mild pick-me-up from the caffeine, but you also get the focus and mood-enhancing effects of DMAA.
The amino acid lineup may not be the best, but this will feel worlds better than any other product on the market. Next time you’re dragging on energy, skip the coffee maker, and serve us a helping of Off the Chain!
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- Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr. 2006 Feb;136(2):533S-537S.
- Sharp CP, Pearson DR. Amino acid supplements and recovery from high-intensity resistance training. J Strength Cond Res. 2010 Apr;24(4):1125-30.
- The Effects of Epigallocatechin-3-Gallate on Thermogenesis and Fat Oxidation in Obese Men: A Pilot Study
- Effects of the long term ingestion of tea catechins on Energy Expenditure and Dietary fat oxidation in healthy subjects
- Wang Y, Yang Z, Wei X; Sugar compositions, α-glucosidase inhibitory and amylase inhibitory activities of polysaccharides from leaves and flowers of Camellia sinensis obtained by different extraction methods . Int J Biol Macromol. (2010)
- Juhel C, et al; Green tea extract (AR25) inhibits lipolysis of triglycerides in gastric and duodenal medium in vitro . J Nutr Biochem. (2000)
- McCarthy CG, Farney TM, Canale RE et al; “A Finished Dietary Supplement Stimulates Lipolysis and Metabolic Rate in Young Men and Women”; Nutrition and Metabolic Insights 2012:5 23-31; Available athttps://blog.priceplow.com/wp-content/uploads/a-finished-dietary-supplement-stimulantes-lipolysis-and-metabolic-rate-in-young-men-and-women.pdf
- McCarthy CG, Canale RE, Alleman Jr. RJ et al; “Biochemical and Anthropometric Effects of a Weight Loss Dietary Supplement in Healthy Men and Women”; Nutrition and Metabolic Insights 2012:5 13-22; Available at https://blog.priceplow.com/wp-content/uploads/biochemical-and-anthropometric-effects-of-a-weight-loss-dietary-supplement-in-healthy-men-and-women.pdf
- Farney TM, McCarthy, CG, Canale R et al.; “Hemodynamic and Hematologic Profile of Healthy Adults Ingesting Dietary Supplements Containing 1,3-Dimethylamylamine and Caffeine”; Nutrition and Metabolic Insights; 2012:5 1-12; Available at https://blog.priceplow.com/wp-content/uploads/hemodynamic-and-hematologic-profile-of-healthy-adults-ingesting-dietary-supplements-containing-1-3-dimethylamylamine-and-caffeine.pdf
- Paul N. Whitehead, Brian K. Schilling, Tyler M. Farney, Richard J. Bloomer; “Impact of a Dietary Supplement Containing 1,3-Dimethylamylamine on Blood Pressure and Bloodborne Markers of Health: a 10-Week Intervention Study”; Nutrition and Metabolic Insights; 2012; Available athttps://blog.priceplow.com/wp-content/uploads/impact-of-a-dietary-supplement-containing-1-3-dimethylamylamine-on-blood-pressure-and-bloodborne-markers-of-health-a-10-week-intervention-study.pdf
- Bloomer RJ, Schilling BK, Whitehead PN et al. Safety profile of a dietary supplement containing 1,3-dimethylamylamine: a 10-week intervention study. Nutrition and Metabolic Insights (In Press).
- Bloomer RJ, McCarthy CG, Farney TM et al.; “Effect of caffeine and 1,3-dimethylamylamine on exercise performance and blood markers of lipolysis and oxidative stress in trained men and women.” J Caffeine Res (In Press); Retrieved from http://online.liebertpub.com/doi/abs/10.1089/jcr.2011.0019
- Schilling, Brian, et al.; “Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men”; BMC Pharmacology and Toxicology; 2013; Retrieved from http://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/2050-6511-14-52
- Li, J.S., M. Chen, and Z.C. Li. “Identification and Quantification of Dimethylamylamine in Geranium by Liquid Chromatography Tandem Mass Spectrometry.” Analytical Chemistry Insights 7 (2012): 47–58; Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422085/
- Ping et al. A study on the chemical constituents of geranium oil. Journal of Guizhou Institute of Technology. 1996. 25(1):82-85.
- Fleming, Heather L., Patricia L. Ranaivo, and Paul S. Simone. “Analysis and Confirmation of 1,3-DMAA and 1,4-DMAA in Geranium Plants Using High Performance Liquid Chromatography with Tandem Mass Spectrometry at Ng/g Concentrations.” Analytical Chemistry Insights 7 (2012): 59–78; Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512447/