Disclosure - This is a sponsored post:

Adaptogen Science Night Flight: Take Off to Dreamland

Adaptogen Science Night Flight

Night Flight is a new immune system booster and sleep aid from strong upstart Adaptogen Science.

If you’ve been paying attention to the PricePlow blog and our YouTube channel the past few weeks, you’ve seen a relatively new company popping up pretty frequently. The company we’re referring to is none other than Adaptogen Science, and so far we’re loving their style.

Previously, we’ve covered the brand’s new intra workout amino / hydration supplement Intra Amino Sport and their hydrolyzed whey protein Tasty ISO. Today, we’re focusing on a new sleep aid designed to improve sleep quality as well as joint health and immune system function, titled Night Flight.

We’ve got more details ahead on this new nighttime formula, but first, take a moment to check the best deal and sign up for alerts from PricePlow:

Adaptogen Science Night Flight - Deals and Price Drop Alerts

Get Price Alerts

Also get hot deal alerts

No spam, no scams.

Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer on your own.

Posts are sponsored in part by the retailers and/or brands listed on this page.

Night Flight Ingredients

Night Flight definitely takes a unique spin on the conventional nighttime recovery supplement. Included you’ll find several common ingredients to enhance sleep, joint function, and immunity, but the issue is that everything is wrapped in a massive prop blend, so we have no clue how much of each ingredient we’re getting, which is a big problem.

  • Joint Support Blend (2,580mg)

    • Glucosamine Sulfate

      Adaptogen Science Night Flight Ingredients

      Night Flight brings some much needed joint and immune system support to its novel sleep aid formula.

      One of the most commonly used joint supplements is glucosamine, a naturally occurring compound found in the human body. Research has shown that supplementing with the compound can lower levels of CTX‑II, a biomarker for collagen degradation.[1] Additionally,  glucosamine supplementation has also been shown to improve joint mobility, especially knee flexion and extension.[2]

      Glucosamine often gets a bad rap because users are not patient enough with it. It takes high doses (1500mg/day) and a good amount of time (up to six months!) to really start to work. So knowing that, we appreciate it and recommend it for long-term use for those with joint pain, but urge you never to expect overnight miracles with the ingredient.

    • Chondroitin Sulfate

      Another naturally-occurring compound in the human body, chondroitin is present in cartilage around the joints. Chondroitin is frequently used alongside glucosamine in joint formulas because preliminary studies using the duo showed they were mildly effective in improving joint mobility and function.[3,4]

      However, more recent research has found little to no benefit from chondroitin or the studies noting its benefits were poorly designed and subject to statistical error (attributed to small test groups).[5,6]

    • Hyaluronic Acid

      Adaptogen Science Night Flight Sleep

      In bed or on the sofa, Night Flight can help you fall soundly asleep.

      Hyaluronic acid (HA) is readily found in synovial fluid which helps lubricate joints allowing for ease of movement. Oral supplementation of HA, to the tune of 200mg per day, has been shown to improve symptoms of knee osteoarthristis, especially in younger patients.[7] The question is, how much of hyaluronic acid are we getting here? We just don’t know, and that’s the big problem with prop blends…

    • Bromelain 2400

      Typically found in digestive enzyme blends, bromelain also finds use as an effective pain relief supplement too. Bromelain 2400 is a premium form of the enzyme manufactured by Pure Encapsulations.

      Found prevalently in pineapple, bromelain has a long history of use as an all-natural anti inflammatory to reduce swelling and redness.[8] On top of that, bromelain also has been used as a treatment for the aches and pains associated with the aches and pains brought on by osteoarthritis.[9,10,11]

    • MSM

      MSM Benefits

      Competitive athlete/lifter who needs to get back to full-strength ASAP? One of the MSM Benefits is that it can get you there sooner… and with less pain!

      Another popular joint health supplement is MSM, an organic sulfur-containing molecule found in the body as well as nature. MSM supplies the body with sulfur which it uses for protein synthesis, connective tissue formation, and nutrient absorption.[12]

      MSM helps accelerate recovery from injury[13], improve mobility[14,15], and reduce inflammation.[16] However, that’s only when consuming 3g/day, which you’re definitely not getting here.

      MSM is a great supplement, and we’ve discussed it in great detail before, so check our MSM supplement guide for more info on it. Consider any MSM from Night Flight as “bonus”.

  • Immune Blend (2,100mg)

    • Vitamin C

      Everyone’s favorite vitamin to mega-dose when cold season stops by, vitamin C really needs no introduction. It’s an essential water-soluble vitamin that plays a key role in immune system function. You might be surprised to learn it also bolsters collagen formation and absorption of nonheme iron.[17]

    • L-Glutamine

      The most plentiful amino acid in your muscles, Glutamine is a well-known amino commonly used for its recovery boosting benefits. But, that’s not why it’s here. Glutamine actually plays a key role in boosting gut health and immune system function.[18]

    • Colostrum 30% IgG

      Bovine Colostrum

      Colostrum is rich in numerous compounds, including immunoglobulins, which bolster the immune system and can help fight off the yearly flu.

      Derived from bovine (cow’s), colostrum is a food supplement that contains proteins, immunoglobulins (Ig), growth factors, and other assorted vitamins. Adaptogen includes a form of colostrum delivering 30% IgG — the most common type of antibody found in circulation.[19] IgG binds to pathogens and various other antibodies (bacteria, fungi, etc.) preventing their ability to harm you.

      Better than the flu shot?!

      Here’s a study that many people don’t see a lot: a mere 400mg colostrum outperformed the flu shot,30] and given that this year’s flu shot is estimated to have a dismal 10% success rate,[31] Night Flight could be something really worth adding.

      Unfortunately, due to the prop blend, we’re not sure if we’re getting that 400mg of colostrum here or not.

  • Sleep, Relaxation, & Recovery Blend (530mg)

    • GABA

      GABA is the primary “downer” neurotransmitter in the body frequently supplemented to improve sleep quality.[20] Research notes that GABA increases alpha waves and decreases beta waves[21], which helps prime your body for a productive night’s rest. Alpha waves are the “deep relaxation” waves of the brain, while beta waves are more related to alertness and reasoning.

    • L-Tryptophan & 5-HTP

      Adaptogen Science Night Flight Bed

      Snuggle in for a great night’s sleep with Night Flight by your side.

      We’ve combined these two ingredients for a specific purpose. 5-HTP is a compound derived from L-Tryptophan, which is used to produce serotonin. These two compounds help reduce stress and lessen anxiety, which improve sleep quality.[22,23]

      As a result of the increased serotonin production, you’ll also notice better mood too.

    • Melatonin

      No sleep aid is complete without a dash of melatonin, the hormone that helps regulate sleep patterns. This is the most powerful sleep inducer in Night Flight as various trials have shown successful in treating insomnia.[24,25]

      The issue with melatonin is figuring out the ideal dose for YOU, as research shows benefit with doses ranging for 0.5mg up to 10mg![23,24] There’s even been safety research in to the hundreds of milligrams!

      But more isn’t always better, as a few of the the “best” studies seem to show 2-3mg to be the “sweet spot” for most.[25,26] Again, since this is wrapped in a huge prop blend, we’d guess there’s between 3-5mg melatonin, which is the amount contained in most sleep aids on the market.

Flavors Available

Adaptogen Science Night Flight Flavors

Night Flight is available in two extremely unique flavors to help you slip into a fast, restorative sleep.

Adaptogen Science has released Night Flight in two all-natural, stevia-sweetened flavors which you’re unlikely to find in any other sleep formula (or ANY supplement) for that matter: Passion fruit Tea and Chamomile Lime Tea.

Time to Take the Night Flight

Night Flight is definitely intriguing, but we unfortunately can’t just look at the label and definitively state that it will put you to sleep immediately. Given the ingredients inside, we’re confident there will definitely be long-term health benefits, especially with joints and immune system – but the sleep side of things itself is honestly the biggest question mark!

This one’s going to need to get reviewed. We’ve got a couple tubs of the product on their way, so once we put it to the test (stay tuned to our Supplement Reviews YouTube playlist), we’ll be able to see if our sleep and recovery truly is better with Night Flight.

Adaptogen Science Night Flight - Deals and Price Drop Alerts

Get Price Alerts

Also get hot deal alerts

No spam, no scams.

Disclosure: PricePlow relies on pricing from stores with which we have a business relationship. We work hard to keep pricing current, but you may find a better offer on your own.

Posts are sponsored in part by the retailers and/or brands listed on this page.

Like this Post? We have more on the way...

PricePlow is a price comparison site that asks one simple question: is this worth it?

The honest truth lives here. Follow us on social media below:

References

  1. Duclos ME, et al; Significance of the serum CTX-II level in an osteoarthritis animal model: a 5-month longitudinal study. Osteoarthritis Cartilage. (2010)
  2. Ostojic SM, et al; Glucosamine administration in athletes: effects on recovery of acute knee injury. Res Sports Med. (2007)
  3. Deal CL, Moskowitz RW. Nutraceuticals as therapeutic agents in osteoarthritis. The role of glucosamine, chondroitin sulfate, and collagen hydrolysate. Rheum Dis Clin North Am. (1999)
  4. Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. Drugs Aging. (2007)
  5. Wandel S, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ. (2010)
  6. Reichenbach S, et al. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. Ann Intern Med. (2007)
  7. Tashiro T, Seino S, Sato T, Matsuoka R, Masuda Y, Fukui N. Oral Administration of Polymer Hyaluronic Acid Alleviates Symptoms of Knee Osteoarthritis: A Double-Blind, Placebo-Controlled Study over a 12-Month Period. The Scientific World Journal. 2012;2012:167928. doi:10.1100/2012/167928. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512263/
  8. Zatuchni GI, Colombi DJ. Bromelains therapy for the prevention of episiotomy pain. Obstet Gynecol. 1967 Feb;29(2):275-8.
  9. Brien S, Lewith G, Walker AF, Middleton R, Prescott P, Bundy R. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM. 2006 Dec;99(12):841-50.
  10. Brien S, Lewith G, Walker A, Hicks SM, Middleton D. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies. Evid Based Complement Alternat Med. 2004 Dec;1(3):251-257. Epub 2004 Oct 6.
  11. Hale LP, Chichlowski M, Trinh CT, Greer PK. Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis. Inflamm Bowel Dis. 2010 Dec;16(12):2012-21. doi: 10.1002/ibd.21320.
  12. Brosnan JT, Brosnan ME. The Sulfur-Containing Amino Acids: An Overview. J Nutr. 2006;136(6):1636S-1640. http://jn.nutrition.org/cgi/content/long/136/6/1636S
  13. Peel S. et al. The Effects of MSM Supplementation on Knee Kinetics during Running, Muscle Strength, and Muscle Soreness following Eccentric Exercise- Induced Quadriceps Damage. Presented at American Society for Biomechanics Conference Aug, 2015. https://www.docdroid.net/a3czJbh/peel-2015.pdf.html
  14. Pagonis TA, Givissis PK, Kritis AC, Christodoulou AC. The Effect of Methylsulfonylmethane on Osteoarthritic Large Joints and Mobility. International Journal of Orthopaedics 2014; 1(1): 19-24. http://www.ghrnet.org/index.php/ijo/article/view/745
  15. Kim et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. OsteoArthritis and Cartilage 2006, 14:286-294. http://www.oarsijournal.com/article/S1063-4584(05)00285-2/fulltext (Full PDF available at http://www.ghrnet.org/index.php/ijo/article/download/745/857
  16. Usha, P.R. & Naidu, M.U.R. Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfonylmethane and their Combination in Osteoarthritis. Clin. Drug Investig. (2004) 24: 353. doi:10.2165/00044011-200424060-00005. http://docdro.id/84iXcMd
  17. Gershoff SN. Vitamin C (ascorbic acid): new roles, new requirements? Nutr Rev 1993;51:313-26. https://www.ncbi.nlm.nih.gov/pubmed/8108031
  18. Castell LM, Bevan SJ, Calder P, Newsholme EA. The role of glutamine in the immune system and in intestinal function in catabolic states. Amino Acids. 1994;7(3):231-243. doi:10.1007/BF00807699. https://www.ncbi.nlm.nih.gov/pubmed/24186121
  19. Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill
  20. https://books.google.com/books?id=N7zds_HN9r4C&pg=PA102&lpg=PA102&dq=3-oh-gaba+study&source=bl&ots=eiIojy_m7g&sig=mj2mLyef7cUOitm0M_-8xu-MwO4&hl=en&sa=X&ved=0ahUKEwjy4bPupazWAhXiyFQKHUo6C0cQ6AEIPzAD#v=onepage&q=3-oh-gaba%20study&f=false
  21. Abdou, A; Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.; Department of Research and Development, Pharma Foods International Co. Ltd.; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16971751
  22. Shell W, et al; A randomized, placebo-controlled trial of an amino acid preparation on timing and quality of sleep . Am J Ther. (2010)
  23. Emanuele E, et al; An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress . Neuro Endocrinol Lett. (2010)
  24. Van Geijlswijk, Ingeborg M. et al. “Evaluation of Sleep, Puberty and Mental Health in Children with Long-Term Melatonin Treatment for Chronic Idiopathic Childhood Sleep Onset Insomnia.” Psychopharmacology 216.1 (2011): 111–120. PMC; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21340475
  25. Lemoine, P; Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. Journal of Sleep Research, 16: 372–380 (2007); Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2869.2007.00613.x/full
  26. Hack, L; The Effects of Low-Dose 0.5-mg Melatonin on the Free-Running Circadian Rhythms of Blind Subjects; J Biol Rhythms October 2003 18: 420-429; Retrieved from http://jbr.sagepub.com/cgi/pmidlookup?view=long&pmid=14582858
  27. Robert L. Sack; Entrainment of Free-Running Circadian Rhythms by Melatonin in Blind People; N Engl J Med 2000; 343:1070-1077 October 12, 2000 DOI: 10.1056/NEJM200010123431503; Retrieved from http://www.nejm.org/doi/full/10.1056/NEJM200010123431503#t=article
  28. Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database of Systematic Reviews 2002, Issue 2. Art. No.: CD001520. DOI: 10.1002/14651858.CD001520; Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12076414
  29. Van Geijlswijk, Ingeborg M. et al. “Evaluation of Sleep, Puberty and Mental Health in Children with Long-Term Melatonin Treatment for Chronic Idiopathic Childhood Sleep Onset Insomnia.” Psychopharmacology 216.1 (2011): 111–120; Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111733/
  30. http://journals.sagepub.com/doi/abs/10.1177/1076029606295957
  31. https://www.cbsnews.com/news/this-years-flu-vaccine-may-only-be-10-effective-experts-warn/
Posted in , by Mike | Tagged , , , , , , , , , , , , , . | No Comments

Comments and Discussion (Powered by the PricePlow Forum)